pioglitazone has been researched along with Acute Edematous Pancreatitis in 8 studies
Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study investigated the therapeutic effect and potential mechanism of pioglitazone in rats with severe acute pancreatitis (SAP)." | 7.85 | Therapeutic effect and potential mechanism of pioglitazone in rats with severe acute pancreatitis. ( Chun, Z; Hai, W; Ping, X; Zhi-Wen, Y, 2017) |
| "To determine the effect of pioglitazone, a specific peroxisome proliferator-activated receptor-gamma (PPARgamma) ligand, on development of severe acute pancreatitis (SAP) and expression of nuclear factor-kappa B (NF-kappaB) and intercellular adhesion molecule-1 (ICAM-1) in the pancreas." | 7.74 | Pioglitazone attenuates the severity of sodium taurocholate-induced severe acute pancreatitis. ( Chen, J; Chen, LQ; Hou, XH; Lv, LH; Xie, Y; Xu, P; Zhou, XJ, 2007) |
| "To determine the effect of pioglitazone, a specific peroxisome proliferator-activated receptor-gamma (PPARgamma) ligand, on the development of acute pancreatitis (AP) and on the expression of heat shock protein 70 (HSP70) in the pancreas." | 7.73 | Pioglitazone, a specific ligand of peroxisome proliferator-activated receptor-gamma, protects pancreas against acute cerulein-induced pancreatitis. ( Burnat, G; Ceranowicz, P; Dembinski, A; Dembinski, M; Hahn, EG; Konturek, PC; Konturek, SJ; Tomaszewska, R; Warzecha, Z, 2005) |
| "Pioglitazone was administered prophylactically and pancreatic inflammation was assessed." | 5.38 | Pioglitazone, a PPAR-γ activator, attenuates the severity of cerulein-induced acute pancreatitis by modulating early growth response-1 transcription factor. ( Chen, G; Liu, J; Wan, H; Yuan, Y, 2012) |
| " This study investigated the therapeutic effect and potential mechanism of pioglitazone in rats with severe acute pancreatitis (SAP)." | 3.85 | Therapeutic effect and potential mechanism of pioglitazone in rats with severe acute pancreatitis. ( Chun, Z; Hai, W; Ping, X; Zhi-Wen, Y, 2017) |
| "AR42j cells pretreated with the peroxisome proliferator-activated receptor-γ agonist pioglitazone were activated by cerulein as an in vitro model of acute pancreatitis." | 3.83 | Apoptotic Mechanisms of Peroxisome Proliferator-Activated Receptor-γ Activation in Acinar Cells During Acute Pancreatitis. ( Chen, C; Lou, XL; Xu, P, 2016) |
| "Severe acute pancreatitis (SAP) and mild acute pancreatitis (MAP) were induced and pre-treated with pioglitazone, which is a ligand of PPAR-γ." | 3.79 | Effects of peroxisome proliferator-activated receptor-γ activation on apoptosis in rats with acute pancreatitis. ( Chen, C; Lou, XL; Xu, P; Yang, ZW, 2013) |
| "To determine the effect of pioglitazone, a specific peroxisome proliferator-activated receptor-gamma (PPARgamma) ligand, on development of severe acute pancreatitis (SAP) and expression of nuclear factor-kappa B (NF-kappaB) and intercellular adhesion molecule-1 (ICAM-1) in the pancreas." | 3.74 | Pioglitazone attenuates the severity of sodium taurocholate-induced severe acute pancreatitis. ( Chen, J; Chen, LQ; Hou, XH; Lv, LH; Xie, Y; Xu, P; Zhou, XJ, 2007) |
| "To determine the effect of pioglitazone, a specific peroxisome proliferator-activated receptor-gamma (PPARgamma) ligand, on the development of acute pancreatitis (AP) and on the expression of heat shock protein 70 (HSP70) in the pancreas." | 3.73 | Pioglitazone, a specific ligand of peroxisome proliferator-activated receptor-gamma, protects pancreas against acute cerulein-induced pancreatitis. ( Burnat, G; Ceranowicz, P; Dembinski, A; Dembinski, M; Hahn, EG; Konturek, PC; Konturek, SJ; Tomaszewska, R; Warzecha, Z, 2005) |
| "Pioglitazone was administered prophylactically and pancreatic inflammation was assessed." | 1.38 | Pioglitazone, a PPAR-γ activator, attenuates the severity of cerulein-induced acute pancreatitis by modulating early growth response-1 transcription factor. ( Chen, G; Liu, J; Wan, H; Yuan, Y, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 6 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yamada, T | 1 |
| Hiraoka, E | 1 |
| Miyazaki, T | 1 |
| Sato, J | 1 |
| Ban, N | 1 |
| Hai, W | 1 |
| Ping, X | 1 |
| Zhi-Wen, Y | 1 |
| Chun, Z | 1 |
| Xu, P | 3 |
| Lou, XL | 2 |
| Chen, C | 2 |
| Yang, ZW | 1 |
| Nicolau Ramis, J | 1 |
| Masmiquel Comas, L | 1 |
| Wan, H | 1 |
| Yuan, Y | 1 |
| Liu, J | 1 |
| Chen, G | 1 |
| Konturek, PC | 1 |
| Dembinski, A | 1 |
| Warzecha, Z | 1 |
| Burnat, G | 1 |
| Ceranowicz, P | 1 |
| Hahn, EG | 1 |
| Dembinski, M | 1 |
| Tomaszewska, R | 1 |
| Konturek, SJ | 1 |
| Zhou, XJ | 1 |
| Chen, LQ | 1 |
| Chen, J | 1 |
| Xie, Y | 1 |
| Lv, LH | 1 |
| Hou, XH | 1 |
8 other studies available for pioglitazone and Acute Edematous Pancreatitis
| Article | Year |
|---|---|
Diabetes as First Manifestation of Autoimmune Pancreatitis.
Topics: Adrenal Cortex Hormones; Aged; Autoimmune Diseases; Diabetes Complications; Diabetes Mellitus; Dysli | 2017 |
Therapeutic effect and potential mechanism of pioglitazone in rats with severe acute pancreatitis.
Topics: Amylases; Animals; Anti-Inflammatory Agents; Blotting, Western; CARD Signaling Adaptor Proteins; Cyt | 2017 |
Effects of peroxisome proliferator-activated receptor-γ activation on apoptosis in rats with acute pancreatitis.
Topics: Animals; Apoptosis; Caspase 3; Hypoglycemic Agents; Male; Pancreatitis; Phosphorylation; Pioglitazon | 2013 |
Apoptotic Mechanisms of Peroxisome Proliferator-Activated Receptor-γ Activation in Acinar Cells During Acute Pancreatitis.
Topics: Acinar Cells; Acute Disease; Amylases; Anilides; Animals; Apoptosis; bcl-2-Associated X Protein; Blo | 2016 |
[The new antidiabetic agents in the firing line.... safety reasons or witch hunt?].
Topics: Animals; Breast Neoplasms; Calcitonin; Carcinoma, Medullary; Clinical Trials as Topic; Comorbidity; | 2012 |
Pioglitazone, a PPAR-γ activator, attenuates the severity of cerulein-induced acute pancreatitis by modulating early growth response-1 transcription factor.
Topics: Acinar Cells; Acute Disease; Anilides; Animals; Cell Line, Tumor; Ceruletide; Chemokine CCL2; Chemok | 2012 |
Pioglitazone, a specific ligand of peroxisome proliferator-activated receptor-gamma, protects pancreas against acute cerulein-induced pancreatitis.
Topics: Animals; Ceruletide; DNA; Dose-Response Relationship, Drug; HSP70 Heat-Shock Proteins; Interleukin-1 | 2005 |
Pioglitazone attenuates the severity of sodium taurocholate-induced severe acute pancreatitis.
Topics: Acute Disease; Animals; Cholagogues and Choleretics; Hypoglycemic Agents; Intercellular Adhesion Mol | 2007 |