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pioglitazone and Acute Edematous Pancreatitis

pioglitazone has been researched along with Acute Edematous Pancreatitis in 8 studies

Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.

Research Excerpts

ExcerptRelevanceReference
" This study investigated the therapeutic effect and potential mechanism of pioglitazone in rats with severe acute pancreatitis (SAP)."7.85Therapeutic effect and potential mechanism of pioglitazone in rats with severe acute pancreatitis. ( Chun, Z; Hai, W; Ping, X; Zhi-Wen, Y, 2017)
"To determine the effect of pioglitazone, a specific peroxisome proliferator-activated receptor-gamma (PPARgamma) ligand, on development of severe acute pancreatitis (SAP) and expression of nuclear factor-kappa B (NF-kappaB) and intercellular adhesion molecule-1 (ICAM-1) in the pancreas."7.74Pioglitazone attenuates the severity of sodium taurocholate-induced severe acute pancreatitis. ( Chen, J; Chen, LQ; Hou, XH; Lv, LH; Xie, Y; Xu, P; Zhou, XJ, 2007)
"To determine the effect of pioglitazone, a specific peroxisome proliferator-activated receptor-gamma (PPARgamma) ligand, on the development of acute pancreatitis (AP) and on the expression of heat shock protein 70 (HSP70) in the pancreas."7.73Pioglitazone, a specific ligand of peroxisome proliferator-activated receptor-gamma, protects pancreas against acute cerulein-induced pancreatitis. ( Burnat, G; Ceranowicz, P; Dembinski, A; Dembinski, M; Hahn, EG; Konturek, PC; Konturek, SJ; Tomaszewska, R; Warzecha, Z, 2005)
"Pioglitazone was administered prophylactically and pancreatic inflammation was assessed."5.38Pioglitazone, a PPAR-γ activator, attenuates the severity of cerulein-induced acute pancreatitis by modulating early growth response-1 transcription factor. ( Chen, G; Liu, J; Wan, H; Yuan, Y, 2012)
" This study investigated the therapeutic effect and potential mechanism of pioglitazone in rats with severe acute pancreatitis (SAP)."3.85Therapeutic effect and potential mechanism of pioglitazone in rats with severe acute pancreatitis. ( Chun, Z; Hai, W; Ping, X; Zhi-Wen, Y, 2017)
"AR42j cells pretreated with the peroxisome proliferator-activated receptor-γ agonist pioglitazone were activated by cerulein as an in vitro model of acute pancreatitis."3.83Apoptotic Mechanisms of Peroxisome Proliferator-Activated Receptor-γ Activation in Acinar Cells During Acute Pancreatitis. ( Chen, C; Lou, XL; Xu, P, 2016)
"Severe acute pancreatitis (SAP) and mild acute pancreatitis (MAP) were induced and pre-treated with pioglitazone, which is a ligand of PPAR-γ."3.79Effects of peroxisome proliferator-activated receptor-γ activation on apoptosis in rats with acute pancreatitis. ( Chen, C; Lou, XL; Xu, P; Yang, ZW, 2013)
"To determine the effect of pioglitazone, a specific peroxisome proliferator-activated receptor-gamma (PPARgamma) ligand, on development of severe acute pancreatitis (SAP) and expression of nuclear factor-kappa B (NF-kappaB) and intercellular adhesion molecule-1 (ICAM-1) in the pancreas."3.74Pioglitazone attenuates the severity of sodium taurocholate-induced severe acute pancreatitis. ( Chen, J; Chen, LQ; Hou, XH; Lv, LH; Xie, Y; Xu, P; Zhou, XJ, 2007)
"To determine the effect of pioglitazone, a specific peroxisome proliferator-activated receptor-gamma (PPARgamma) ligand, on the development of acute pancreatitis (AP) and on the expression of heat shock protein 70 (HSP70) in the pancreas."3.73Pioglitazone, a specific ligand of peroxisome proliferator-activated receptor-gamma, protects pancreas against acute cerulein-induced pancreatitis. ( Burnat, G; Ceranowicz, P; Dembinski, A; Dembinski, M; Hahn, EG; Konturek, PC; Konturek, SJ; Tomaszewska, R; Warzecha, Z, 2005)
"Pioglitazone was administered prophylactically and pancreatic inflammation was assessed."1.38Pioglitazone, a PPAR-γ activator, attenuates the severity of cerulein-induced acute pancreatitis by modulating early growth response-1 transcription factor. ( Chen, G; Liu, J; Wan, H; Yuan, Y, 2012)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's6 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yamada, T1
Hiraoka, E1
Miyazaki, T1
Sato, J1
Ban, N1
Hai, W1
Ping, X1
Zhi-Wen, Y1
Chun, Z1
Xu, P3
Lou, XL2
Chen, C2
Yang, ZW1
Nicolau Ramis, J1
Masmiquel Comas, L1
Wan, H1
Yuan, Y1
Liu, J1
Chen, G1
Konturek, PC1
Dembinski, A1
Warzecha, Z1
Burnat, G1
Ceranowicz, P1
Hahn, EG1
Dembinski, M1
Tomaszewska, R1
Konturek, SJ1
Zhou, XJ1
Chen, LQ1
Chen, J1
Xie, Y1
Lv, LH1
Hou, XH1

Other Studies

8 other studies available for pioglitazone and Acute Edematous Pancreatitis

ArticleYear
Diabetes as First Manifestation of Autoimmune Pancreatitis.
    The American journal of the medical sciences, 2017, Volume: 353, Issue:5

    Topics: Adrenal Cortex Hormones; Aged; Autoimmune Diseases; Diabetes Complications; Diabetes Mellitus; Dysli

2017
Therapeutic effect and potential mechanism of pioglitazone in rats with severe acute pancreatitis.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2017, Dec-11, Volume: 51, Issue:2

    Topics: Amylases; Animals; Anti-Inflammatory Agents; Blotting, Western; CARD Signaling Adaptor Proteins; Cyt

2017
Effects of peroxisome proliferator-activated receptor-γ activation on apoptosis in rats with acute pancreatitis.
    Digestive diseases and sciences, 2013, Volume: 58, Issue:12

    Topics: Animals; Apoptosis; Caspase 3; Hypoglycemic Agents; Male; Pancreatitis; Phosphorylation; Pioglitazon

2013
Apoptotic Mechanisms of Peroxisome Proliferator-Activated Receptor-γ Activation in Acinar Cells During Acute Pancreatitis.
    Pancreas, 2016, Volume: 45, Issue:2

    Topics: Acinar Cells; Acute Disease; Amylases; Anilides; Animals; Apoptosis; bcl-2-Associated X Protein; Blo

2016
[The new antidiabetic agents in the firing line.... safety reasons or witch hunt?].
    Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2012, Volume: 59, Issue:1

    Topics: Animals; Breast Neoplasms; Calcitonin; Carcinoma, Medullary; Clinical Trials as Topic; Comorbidity;

2012
Pioglitazone, a PPAR-γ activator, attenuates the severity of cerulein-induced acute pancreatitis by modulating early growth response-1 transcription factor.
    Translational research : the journal of laboratory and clinical medicine, 2012, Volume: 160, Issue:2

    Topics: Acinar Cells; Acute Disease; Anilides; Animals; Cell Line, Tumor; Ceruletide; Chemokine CCL2; Chemok

2012
Pioglitazone, a specific ligand of peroxisome proliferator-activated receptor-gamma, protects pancreas against acute cerulein-induced pancreatitis.
    World journal of gastroenterology, 2005, Oct-28, Volume: 11, Issue:40

    Topics: Animals; Ceruletide; DNA; Dose-Response Relationship, Drug; HSP70 Heat-Shock Proteins; Interleukin-1

2005
Pioglitazone attenuates the severity of sodium taurocholate-induced severe acute pancreatitis.
    World journal of gastroenterology, 2007, Apr-07, Volume: 13, Issue:13

    Topics: Acute Disease; Animals; Cholagogues and Choleretics; Hypoglycemic Agents; Intercellular Adhesion Mol

2007