Page last updated: 2024-11-02

pioglitazone and Acromegaly

pioglitazone has been researched along with Acromegaly in 4 studies

Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.

Acromegaly: A condition caused by prolonged exposure to excessive HUMAN GROWTH HORMONE in adults. It is characterized by bony enlargement of the FACE; lower jaw (PROGNATHISM); hands; FEET; HEAD; and THORAX. The most common etiology is a GROWTH HORMONE-SECRETING PITUITARY ADENOMA. (From Joynt, Clinical Neurology, 1992, Ch36, pp79-80)

Research Excerpts

ExcerptRelevanceReference
"Short-term treatment with conventional doses of pioglitazone did not improve biochemical measures of disease activity in acromegaly."7.78Pioglitazone in acromegaly - an open-label, prospective study. ( Gamble, G; Goh, J; Grey, A; Holdaway, I; Kim, DD; Panossian, Z, 2012)
"Pioglitazone treatment might be considered as a choice for similar cases of diabetes secondary to acromegaly."7.72A case of secondary diabetes mellitus with acromegaly improved by pioglitazone. ( Aiba, N; Arakawa, Y; Kamoshida, S; Kanou, M; Komine, F; Nabe, K; Nakamura, S; Nirei, K; Okubo, H; Otsuka, M; Sawada, S; Tamura, K; Uchiyama, T; Watanabe, A, 2004)
"Short-term treatment with conventional doses of pioglitazone did not improve biochemical measures of disease activity in acromegaly."3.78Pioglitazone in acromegaly - an open-label, prospective study. ( Gamble, G; Goh, J; Grey, A; Holdaway, I; Kim, DD; Panossian, Z, 2012)
"Sixteen patients with acromegaly undergoing pituitary surgery (and 16 patients with type 2 diabetes treated with pioglitazone) were included."3.73Effect of pituitary surgery in patients with acromegaly on adiponectin serum concentrations and alanine aminotransferase activity. ( A Spinas, G; Bernays, R; Brändle, M; Schmid, C; Seiler, H; Wiesli, P; Zapf, J; Zwimpfer, C, 2005)
"Pioglitazone treatment might be considered as a choice for similar cases of diabetes secondary to acromegaly."3.72A case of secondary diabetes mellitus with acromegaly improved by pioglitazone. ( Aiba, N; Arakawa, Y; Kamoshida, S; Kanou, M; Komine, F; Nabe, K; Nakamura, S; Nirei, K; Okubo, H; Otsuka, M; Sawada, S; Tamura, K; Uchiyama, T; Watanabe, A, 2004)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Grasso, LF1
Pivonello, R1
Colao, A1
Kim, DD1
Goh, J1
Panossian, Z1
Gamble, G1
Holdaway, I1
Grey, A1
Watanabe, A1
Komine, F1
Nirei, K1
Tamura, K1
Nabe, K1
Aiba, N1
Kamoshida, S1
Otsuka, M1
Okubo, H1
Kanou, M1
Sawada, S1
Uchiyama, T1
Nakamura, S1
Arakawa, Y1
Wiesli, P1
Bernays, R1
Brändle, M1
Zwimpfer, C1
Seiler, H1
Zapf, J1
A Spinas, G1
Schmid, C1

Reviews

1 review available for pioglitazone and Acromegaly

ArticleYear
Investigational therapies for acromegaly.
    Expert opinion on investigational drugs, 2013, Volume: 22, Issue:8

    Topics: Acromegaly; Dacarbazine; Drugs, Investigational; Human Growth Hormone; Humans; Octreotide; Pioglitaz

2013

Other Studies

3 other studies available for pioglitazone and Acromegaly

ArticleYear
Pioglitazone in acromegaly - an open-label, prospective study.
    Clinical endocrinology, 2012, Volume: 77, Issue:4

    Topics: Acromegaly; Adult; Female; Human Growth Hormone; Humans; Insulin-Like Growth Factor I; Male; Middle

2012
A case of secondary diabetes mellitus with acromegaly improved by pioglitazone.
    Diabetic medicine : a journal of the British Diabetic Association, 2004, Volume: 21, Issue:9

    Topics: Acromegaly; Blood Glucose; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Humans; Hypoglycemi

2004
Effect of pituitary surgery in patients with acromegaly on adiponectin serum concentrations and alanine aminotransferase activity.
    Clinica chimica acta; international journal of clinical chemistry, 2005, Volume: 352, Issue:1-2

    Topics: Acromegaly; Adiponectin; Adult; Aged; Alanine Transaminase; Diabetes Mellitus, Type 2; Female; Human

2005