pioglitazone has been researched along with Absence Status in 2 studies
Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of the present study was to determine if modulation by PPAR-γ could attenuate pilocarpine-induced seizures and decrease neuronal excitability." | 3.91 | The Protective Role of Peroxisome Proliferator-Activated Receptor-Gamma in Seizure and Neuronal Excitotoxicity. ( Chu, FL; Huang, CW; Hung, TY; Wu, DC; Wu, SN, 2019) |
| " The present study investigated the effect of the PPAR-γ agonist, pioglitazone, on the mammalian target of rapamycin (mTOR) signaling pathway in a rat model of pentylenetetrazol (PTZ)-induced status epilepticus (SE)." | 3.81 | Peroxisome proliferator-activated receptor-γ agonist inhibits the mammalian target of rapamycin signaling pathway and has a protective effect in a rat model of status epilepticus. ( Liu, Y; San, YZ; Shi, PP; Zhang, Y; Zhu, YL, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hung, TY | 1 |
| Chu, FL | 1 |
| Wu, DC | 1 |
| Wu, SN | 1 |
| Huang, CW | 1 |
| San, YZ | 1 |
| Liu, Y | 1 |
| Zhang, Y | 1 |
| Shi, PP | 1 |
| Zhu, YL | 1 |
2 other studies available for pioglitazone and Absence Status
| Article | Year |
|---|---|
The Protective Role of Peroxisome Proliferator-Activated Receptor-Gamma in Seizure and Neuronal Excitotoxicity.
Topics: Animals; Blood Glucose; Blood-Brain Barrier; Hippocampus; Ion Channel Gating; Mice, Inbred C57BL; Ne | 2019 |
Peroxisome proliferator-activated receptor-γ agonist inhibits the mammalian target of rapamycin signaling pathway and has a protective effect in a rat model of status epilepticus.
Topics: Animals; CA3 Region, Hippocampal; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Immunoh | 2015 |