Page last updated: 2024-08-24

pinocembrin and Disease Models, Animal

pinocembrin has been researched along with Disease Models, Animal in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (4.55)29.6817
2010's12 (54.55)24.3611
2020's9 (40.91)2.80

Authors

AuthorsStudies
Chen, X; Fo, Y; Guo, Y; Qu, C; Sun, Y; Wan, W; Yang, B; Ye, T; Zhang, C1
Cumming, A; Derseh, HB; Goodger, JQD; Palombo, EA; Samuel, CS; Scheerlinck, JY; Snibson, K; Woodrow, IE1
Feng, N; Han, G; Hou, X; Li, Y; Liu, W; Wu, H; Xing, B; Zhang, J1
Hu, T; Jiang, CL; Li, JM; Wang, W1
Chen, X; Liu, Z; Wan, W; Yang, B; Ye, T; Yu, Y; Zhang, C1
Bo, Y; Cui, Z; Tianxin, Y; Weiguo, W; Yi, Y; Zhangchi, L1
Habtemariam, S1
Gu, X; Tu, J; Wang, W; Xu, L; Zheng, L1
Dou, W; Luo, X; Mani, S; Ren, J; Ren, Y; Wang, Z; Yu, Z; Yue, B; Zhang, J1
Chen, X; Guo, Y; Liang, J; Liu, X; Qu, C; Shi, S; Sun, Y; Yang, B; Ye, T; Zhang, C1
Ahmed, LA; El-Maraghy, SA; Rizk, SM1
Du, Q; Gu, X; Shen, H; Zhang, Q; Zhu, Z1
Chang, J; Du, G; Kong, L; Li, L; Ma, Y; Song, J; Zhang, W; Zhu, Z1
Bai, X; Hu, W; Xu, J; Yu, D; Zhang, P1
Chen, W; Shen, C; Sun, Y; Tao, J; Yan, G1
Du, GH; Fang, LH; Gao, M; Pang, XB; Wang, SB1
Bai, XY; Du, GH; Huang, C; Li, JZ; Li, L; Li, YJ; Liu, R; Song, JK; Wu, CX; Xie, T; Zhang, L; Zhang, TT; Zhang, X; Zhou, D1
Du, G; Li, L; Wu, S; Zhang, W; Zhao, G1
Chen, BN; Du, GH; Gao, M; Li, YJ; Shi, LL; Wang, L; Zhang, HA1
Du, G; Gao, M; Liu, R; Meng, F; Sun, J; Wang, Y; Wu, C; Xuan, Z; Yang, F; Yu, X1
Du, GH; Liu, R; Tian, S; Wu, CX; Yang, F; Zhang, L; Zhang, TT; Zhou, D1
Chen, CS; Chen, HM; Chen, LC; Chen, RJ; Ho, YS; Lai, YC; Lee, WS; Wang, YJ; Wu, CH1

Reviews

1 review(s) available for pinocembrin and Disease Models, Animal

ArticleYear
The Nrf2/HO-1 Axis as Targets for Flavanones: Neuroprotection by Pinocembrin, Naringenin, and Eriodictyol.
    Oxidative medicine and cellular longevity, 2019, Volume: 2019

    Topics: Animals; Disease Models, Animal; Flavanones; NF-E2-Related Factor 2; Rats; Reactive Oxygen Species

2019

Other Studies

21 other study(ies) available for pinocembrin and Disease Models, Animal

ArticleYear
Pinocembrin ameliorates post-infarct heart failure through activation of Nrf2/HO-1 signaling pathway.
    Molecular medicine (Cambridge, Mass.), 2021, 09-06, Volume: 27, Issue:1

    Topics: Animals; Antioxidants; Biomarkers; Disease Management; Disease Models, Animal; Disease Susceptibility; Echocardiography; Flavanones; Heart Failure; Heme Oxygenase-1; Immunohistochemistry; Male; Myocardial Infarction; Myocytes, Cardiac; Myofibroblasts; NF-E2-Related Factor 2; Oxidative Stress; Rats; Reactive Oxygen Species; Signal Transduction

2021
The efficacy and safety of pinocembrin in a sheep model of bleomycin-induced pulmonary fibrosis.
    PloS one, 2021, Volume: 16, Issue:12

    Topics: Animals; Antifibrotic Agents; Bleomycin; Bronchoalveolar Lavage Fluid; CD4-Positive T-Lymphocytes; Disease Models, Animal; Eucalyptus; Flavanones; Lung; Neutrophils; Pulmonary Fibrosis; Respiratory Function Tests; Severity of Illness Index; Sheep; Treatment Outcome

2021
Pinocembrin relieves hip fracture-induced pain by repressing spinal substance P signaling in aged rats.
    Journal of neurophysiology, 2022, 02-01, Volume: 127, Issue:2

    Topics: Aging; Animals; Disease Models, Animal; Flavanones; Hip Fractures; Indoles; Male; Neurokinin-1 Receptor Antagonists; Nociceptive Pain; Pain; Piperidines; Rats; Rats, Sprague-Dawley; Signal Transduction; Substance P

2022
Pinocembrin ameliorates depressive-like behaviors by regulating P2X7/TRL4 receptors expression in mouse hippocampus.
    Behavioural pharmacology, 2022, 08-01, Volume: 33, Issue:5

    Topics: Animals; Behavior, Animal; Cytokines; Depression; Depressive Disorder, Major; Disease Models, Animal; Flavanones; Hippocampus; Humans; Male; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Receptors, Purinergic P2X7; Stress, Psychological; Toll-Like Receptor 4

2022
Pinocembrin alleviates the susceptibility to atrial fibrillation in isoproterenol-induced rats.
    Biochemical and biophysical research communications, 2022, 12-25, Volume: 636, Issue:Pt 1

    Topics: Animals; Atrial Fibrillation; Atrial Remodeling; Caspase 1; Collagen Type I; Connexins; Disease Models, Animal; Fibrosis; Heart Atria; Inflammation; Ion Channels; Isoproterenol; NLR Family, Pyrin Domain-Containing 3 Protein; Rats; Rats, Sprague-Dawley

2022
Pinocembrin attenuates susceptibility to atrial fibrillation in rats with pulmonary arterial hypertension.
    European journal of pharmacology, 2023, Dec-05, Volume: 960

    Topics: Animals; Atrial Fibrillation; Disease Models, Animal; Familial Primary Pulmonary Hypertension; Fibrosis; Monocrotaline; Pulmonary Arterial Hypertension; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Vascular Remodeling

2023
Pinocembrin mitigates depressive-like behaviors induced by chronic unpredictable mild stress through ameliorating neuroinflammation and apoptosis.
    Molecular medicine (Cambridge, Mass.), 2020, 05-27, Volume: 26, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Apoptosis; Behavior, Animal; Cytokines; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Flavanones; Hippocampus; Male; Mice; Oxidative Stress; Reactive Oxygen Species; Signal Transduction; Stress, Psychological

2020
Pinocembrin alleviates ulcerative colitis in mice via regulating gut microbiota, suppressing TLR4/MD2/NF-κB pathway and promoting intestinal barrier.
    Bioscience reports, 2020, 07-31, Volume: 40, Issue:7

    Topics: Animals; Caco-2 Cells; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Dose-Response Relationship, Drug; Dysbiosis; Flavanones; Gastrointestinal Microbiome; Humans; Intestinal Mucosa; Lymphocyte Antigen 96; Mice; NF-kappa B; RAW 264.7 Cells; Signal Transduction; Tight Junctions; Toll-Like Receptor 4

2020
Pinocembrin ameliorates arrhythmias in rats with chronic ischaemic heart failure.
    Annals of medicine, 2021, Volume: 53, Issue:1

    Topics: Animals; Arrhythmias, Cardiac; Disease Models, Animal; Flavanones; Heart Failure; Humans; Myocardial Infarction; Nerve Growth Factor; Rats

2021
Pinocembrin ex vivo preconditioning improves the therapeutic efficacy of endothelial progenitor cells in monocrotaline-induced pulmonary hypertension in rats.
    Biochemical pharmacology, 2017, 08-15, Volume: 138

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Biomarkers; Bone Marrow Cells; Bone Marrow Transplantation; Cells, Cultured; Cytokines; Disease Models, Animal; Endothelial Progenitor Cells; Endothelium, Vascular; Flavanones; Graft Rejection; Heart Ventricles; Hypertension, Pulmonary; Lung; Male; Pulmonary Artery; Random Allocation; Rats, Wistar

2017
Pinocembrin attenuates allergic airway inflammation via inhibition of NF-κB pathway in mice.
    International immunopharmacology, 2017, Volume: 53

    Topics: Animals; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Female; Flavanones; Humans; Immunoglobulin E; Inflammation; Lung; Mice; Mice, Inbred BALB C; NF-kappa B; Ovalbumin; Signal Transduction; Th2 Cells

2017
Pinocembrin Protects Blood-Brain Barrier Function and Expands the Therapeutic Time Window for Tissue-Type Plasminogen Activator Treatment in a Rat Thromboembolic Stroke Model.
    BioMed research international, 2018, Volume: 2018

    Topics: Animals; Behavior, Animal; Blood-Brain Barrier; Brain Ischemia; Disease Models, Animal; Disease Progression; Embolism; Flavanones; Humans; Lymphokines; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neuroprotective Agents; Permeability; Platelet-Derived Growth Factor; Rats, Sprague-Dawley; Receptor, Platelet-Derived Growth Factor alpha; Signal Transduction; Stroke; Thrombosis; Tight Junction Proteins; Time Factors; Tissue Plasminogen Activator

2018
Effects of Pinocembrin Pretreatment on Connexin 43 (Cx43) Protein Expression After Rat Myocardial Ischemia-Reperfusion and Cardiac Arrhythmia.
    Medical science monitor : international medical journal of experimental and clinical research, 2018, Jul-19, Volume: 24

    Topics: Animals; Arrhythmias, Cardiac; Connexin 43; Disease Models, Animal; Flavanones; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Rats; Rats, Sprague-Dawley; Up-Regulation

2018
Neuroprotective effects of pinocembrin on ischemia/reperfusion-induced brain injury by inhibiting autophagy.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 106

    Topics: Animals; Autophagy; Beclin-1; Behavior, Animal; Brain Ischemia; CA1 Region, Hippocampal; Cognition; Disease Models, Animal; Flavanones; Male; Maze Learning; Microtubule-Associated Proteins; Motor Activity; Neurons; Neuroprotective Agents; Rats, Sprague-Dawley; Reperfusion Injury; Sequestosome-1 Protein; Sirolimus; Time Factors

2018
Pinocembrin protects rats against cerebral ischemic damage through soluble epoxide hydrolase and epoxyeicosatrienoic acids.
    Chinese journal of natural medicines, 2013, Volume: 11, Issue:3

    Topics: Animals; Arachidonic Acids; Brain; Brain Ischemia; Disease Models, Animal; Epoxide Hydrolases; Flavanones; Humans; Male; Protective Agents; Rats; Rats, Sprague-Dawley

2013
Pinocembrin improves cognition and protects the neurovascular unit in Alzheimer related deficits.
    Neurobiology of aging, 2014, Volume: 35, Issue:6

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Brain-Derived Neurotrophic Factor; Cognition; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Female; Flavanones; Male; MAP Kinase Signaling System; Mice; Neuroprotective Agents; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Signal Transduction

2014
Pinocembrin protects the brain against ischemia-reperfusion injury and reverses the autophagy dysfunction in the penumbra area.
    Molecules (Basel, Switzerland), 2014, Sep-30, Volume: 19, Issue:10

    Topics: Animals; Autophagy; Brain Edema; Brain Infarction; Brain Ischemia; Caspase 3; Disease Models, Animal; Flavanones; Male; Neuroprotective Agents; Rats; Reperfusion Injury

2014
The characteristics of therapeutic effect of pinocembrin in transient global brain ischemia/reperfusion rats.
    Life sciences, 2011, Mar-14, Volume: 88, Issue:11-12

    Topics: Amino Acids; Animals; Brain Edema; Disease Models, Animal; Dose-Response Relationship, Drug; Flavanones; Injections, Intravenous; Ischemic Attack, Transient; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Time Factors

2011
Pinocembrin attenuates blood-brain barrier injury induced by global cerebral ischemia-reperfusion in rats.
    Brain research, 2011, May-19, Volume: 1391

    Topics: Analysis of Variance; Animals; Blood Pressure; Blood-Brain Barrier; Brain Edema; Brain Ischemia; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Flavanones; Male; Membrane Potential, Mitochondrial; Microscopy, Electron, Transmission; Neurologic Examination; Neuroprotective Agents; Oxygen; Permeability; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Reperfusion Injury

2011
Pinocembrin protects against β-amyloid-induced toxicity in neurons through inhibiting receptor for advanced glycation end products (RAGE)-independent signaling pathways and regulating mitochondrion-mediated apoptosis.
    BMC medicine, 2012, Sep-18, Volume: 10

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Cerebral Cortex; Cognition; Disease Models, Animal; Flavanones; Gene Expression Profiling; Male; Mice; Mitochondria; Nerve Degeneration; Neurons; Neuroprotective Agents; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Signal Transduction

2012
NF-kappaB-activated tissue transglutaminase is involved in ethanol-induced hepatic injury and the possible role of propolis in preventing fibrogenesis.
    Toxicology, 2008, Apr-18, Volume: 246, Issue:2-3

    Topics: Animals; Anti-Infective Agents; Cell Line, Tumor; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanol; Flavanones; Gene Expression Regulation, Enzymologic; GTP-Binding Proteins; Hepatocytes; Humans; Liver Cirrhosis, Experimental; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; Propolis; Protein Glutamine gamma Glutamyltransferase 2; Rats; RNA, Messenger; Transglutaminases

2008