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pindolol and Ventricular Fibrillation

pindolol has been researched along with Ventricular Fibrillation in 12 studies

Pindolol: A moderately lipophilic beta blocker (ADRENERGIC BETA-ANTAGONISTS). It is non-cardioselective and has intrinsic sympathomimetic actions, but little membrane-stabilizing activity. (From Martindale, The Extra Pharmocopoeia, 30th ed, p638)
pindolol : A member of the class of indols which is the 2-hydroxy-3-(isopropylamino)propyl ether derivative of 1H-indol-4-ol.

Ventricular Fibrillation: A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST.

Research Excerpts

ExcerptRelevanceReference
"Metoprolol and other beta-adrenergic blocking drugs are known to exert cardioprotective effects that include significant reduction in occurrence of ventricular fibrillation (VF) following myocardial ischemia and infarction."7.67Effects of metoprolol, alone and in combination with lidocaine, on ventricular fibrillation threshold: comparison with atenolol, propranolol, and pindolol. ( Beil, ME; Cabot, CF; Coram, WM; Olson, RW; Weiss, GB, 1987)
"A study was designed to examine ventricular arrhythmias in the acute phase of experimental myocardial infarction in the pig and to evaluate possible antiarrhythmogenic influence of the beta-adrenergic blocking drug pindolol (Visken) and the calcium antagonist Ro 11-1781."7.66[Ventricular arrhythmias in the acute stage of experimental swine myocardial infarct; effect of the beta blocker pindolol and the calcium antagonist Ro 11-1781]. ( Althaus, U; Dolder, M; Frank, J; Gertsch, M; Gurtner, HP, 1978)
"Metoprolol and other beta-adrenergic blocking drugs are known to exert cardioprotective effects that include significant reduction in occurrence of ventricular fibrillation (VF) following myocardial ischemia and infarction."3.67Effects of metoprolol, alone and in combination with lidocaine, on ventricular fibrillation threshold: comparison with atenolol, propranolol, and pindolol. ( Beil, ME; Cabot, CF; Coram, WM; Olson, RW; Weiss, GB, 1987)
"A study was designed to examine ventricular arrhythmias in the acute phase of experimental myocardial infarction in the pig and to evaluate possible antiarrhythmogenic influence of the beta-adrenergic blocking drug pindolol (Visken) and the calcium antagonist Ro 11-1781."3.66[Ventricular arrhythmias in the acute stage of experimental swine myocardial infarct; effect of the beta blocker pindolol and the calcium antagonist Ro 11-1781]. ( Althaus, U; Dolder, M; Frank, J; Gertsch, M; Gurtner, HP, 1978)
" The latter, however, was taking antiarrhythmic drugs at a dosage less than that proved to be effective during electropharmacological testing."1.27[Value of a serial electropharmacologic study in survivors of a cardiac arrest secondary to ventricular tachycardia or ventricular fibrillation]. ( Delise, P; Di Pede, F; Piccolo, E; Raviele, A, 1984)
"Oxprenolol or pindolol were used as primary drugs in 8 cases."1.26[Therapy of postoperative arrhythmias (author's transl)]. ( Vormittag, E, 1979)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-199011 (91.67)18.7374
1990's1 (8.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Raeder, EA1
Verrier, RL1
Lown, B1
Raviele, A1
Di Pede, F1
Delise, P1
Piccolo, E1
Prengel, AW1
Lindner, KH1
Anhäupl, T1
Vogt, J1
Lurie, KG1
Vormittag, E1
Doshchitsin, VL1
Pozin, VM1
Skuratovskaia, SG1
Gendlin, GE1
Fedorova, IF1
Frank, J1
Dolder, M1
Gertsch, M1
Althaus, U1
Gurtner, HP1
Holmboe, J1
Lilleåsen, P1
Normann, E1
Coram, WM1
Olson, RW1
Beil, ME1
Cabot, CF1
Weiss, GB1
Fitzgerald, JD1
Kenedi, I1
Losonci, A1
Singh, BN1
Jewitt, DE1
Sharma, PL1

Reviews

2 reviews available for pindolol and Ventricular Fibrillation

ArticleYear
The possible role of the ancillary properties of beta adrenoceptor antagonists in the management of angina pectoris.
    Acta medica Scandinavica. Supplementum, 1985, Volume: 694

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angina Pectoris; Animals; Anxiety Disorde

1985
Beta-adrenergic receptor blocking drugs in cardiac arrhythmias.
    Drugs, 1974, Volume: 7, Issue:6

    Topics: Action Potentials; Adrenergic beta-Antagonists; Alprenolol; Arrhythmia, Sinus; Arrhythmias, Cardiac;

1974

Other Studies

10 other studies available for pindolol and Ventricular Fibrillation

ArticleYear
Intrinsic sympathomimetic activity and the effects of beta-adrenergic blocking drugs on vulnerability to ventricular fibrillation.
    Journal of the American College of Cardiology, 1983, Volume: 1, Issue:6

    Topics: Adrenergic beta-Antagonists; Animals; Cardiac Pacing, Artificial; Dogs; Electrophysiology; Female; H

1983
[Value of a serial electropharmacologic study in survivors of a cardiac arrest secondary to ventricular tachycardia or ventricular fibrillation].
    Giornale italiano di cardiologia, 1984, Volume: 14, Issue:9

    Topics: Adult; Aged; Amiodarone; Death, Sudden; Disopyramide; Drug Therapy, Combination; Electrocardiography

1984
Regulation of right atrial beta-adrenoceptors after cardiopulmonary resuscitation in pigs.
    Resuscitation, 1996, Volume: 31, Issue:3

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Blood Circulation; Blood Pressure; C

1996
[Therapy of postoperative arrhythmias (author's transl)].
    Wiener klinische Wochenschrift, 1979, Apr-13, Volume: 91, Issue:8

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Arrhythmias, Cardiac; Atrial Fibrillation; Cardiac Complex

1979
[Prevention of ventricular fibrillation in animal experiments].
    Kardiologiia, 1978, Volume: 18, Issue:4

    Topics: Ajmaline; Animals; Anti-Arrhythmia Agents; Drug Evaluation; Lidocaine; Pindolol; Rats; Ventricular F

1978
[Ventricular arrhythmias in the acute stage of experimental swine myocardial infarct; effect of the beta blocker pindolol and the calcium antagonist Ro 11-1781].
    Schweizerische medizinische Wochenschrift, 1978, Nov-04, Volume: 108, Issue:44

    Topics: Acute Disease; Animals; Arrhythmias, Cardiac; Calcium; Female; Myocardial Infarction; Pindolol; Swin

1978
Pindolol (Viscén) in persistent ventricular fibrillation. A case report.
    Acta anaesthesiologica Scandinavica, 1976, Volume: 20, Issue:1

    Topics: Aged; Aortic Aneurysm; Electric Countershock; Female; Humans; Lidocaine; Pindolol; Resuscitation; Ta

1976
Effects of metoprolol, alone and in combination with lidocaine, on ventricular fibrillation threshold: comparison with atenolol, propranolol, and pindolol.
    Journal of cardiovascular pharmacology, 1987, Volume: 9, Issue:5

    Topics: Animals; Atenolol; Differential Threshold; Dogs; Drug Combinations; Isoproterenol; Lidocaine; Metopr

1987
Effect of beta adrenergic blocking on the arrhythmias following coronary ligation in rat.
    Acta physiologica Academiae Scientiarum Hungaricae, 1973, Volume: 44, Issue:3-4

    Topics: Adrenergic beta-Antagonists; Animals; Arrhythmia, Sinus; Arrhythmias, Cardiac; Cardiac Complexes, Pr

1973
Antiarrhythmic acitivity of pindolol in adrenaline-evoked ventricular arrhythmias in dogs anaesthetized with halothane in oxygen.
    British journal of anaesthesia, 1972, Volume: 44, Issue:12

    Topics: Anesthesia, General; Animals; Blood Pressure; Carotid Arteries; Dogs; Electric Countershock; Electro

1972