pindolol has been researched along with Substance Withdrawal Syndrome in 14 studies
Pindolol: A moderately lipophilic beta blocker (ADRENERGIC BETA-ANTAGONISTS). It is non-cardioselective and has intrinsic sympathomimetic actions, but little membrane-stabilizing activity. (From Martindale, The Extra Pharmocopoeia, 30th ed, p638)
pindolol : A member of the class of indols which is the 2-hydroxy-3-(isopropylamino)propyl ether derivative of 1H-indol-4-ol.
Substance Withdrawal Syndrome: Physiological and psychological symptoms associated with withdrawal from the use of a drug after prolonged administration or habituation. The concept includes withdrawal from smoking or drinking, as well as withdrawal from an administered drug.
| Excerpt | Relevance | Reference |
|---|---|---|
| "1 Pindolol is a beta-adrenoceptor antagonist equally effective on beta 1- and beta 2-adrenoceptors which has a relatively long duration of action." | 2.36 | Pindolol--a beta-adrenoceptor blocking drug with partial agonist activity: clinical pharmacological considerations. ( Aellig, WH, 1982) |
| "Abrupt withdrawal after the chronic administration of propranolol has resulted in clinical syndromes that suggest adrenergic hypersensitivity." | 1.26 | Elevation of beta-adrenergic receptor density in human lymphocytes after propranolol administration. ( Aarons, RD; Gal, J; Hegstrand, LR; Molinoff, PB; Nies, AS, 1980) |
| "Pindolol was given to 10 hypertensive patients in doses of 10 mg b." | 1.26 | Cardiac hyper- and hyporesponsiveness after pindolol withdrawal. ( Langlois, S; Rangno, RE; Stewart, J, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (85.71) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aarons, RD | 1 |
| Nies, AS | 1 |
| Gal, J | 1 |
| Hegstrand, LR | 1 |
| Molinoff, PB | 1 |
| Walden, RJ | 3 |
| Hernandez, J | 1 |
| Yu, Y | 1 |
| Al-Khader, A | 1 |
| Prichard, BN | 3 |
| Aellig, WH | 1 |
| Rangno, RE | 3 |
| Langlois, S | 3 |
| McDevitt, DG | 1 |
| Giudicelli, Y | 1 |
| Lacasa, D | 1 |
| Agli, B | 1 |
| Leneveu, A | 1 |
| Lorenz, D | 1 |
| Stewart, J | 1 |
| Szécsi, E | 1 |
| Kohlschütter, S | 1 |
| Schiess, W | 1 |
| Lang, E | 1 |
| Digranes, O | 1 |
| Tomlinson, B | 2 |
| Graham, B | 2 |
| Smith, C | 1 |
| Betteridge, DJ | 1 |
| Liu, JB | 1 |
| Bolli, P | 1 |
| Amann, FW | 1 |
| Müller, FB | 1 |
| Meyer, B | 1 |
| Burckhardt, D | 1 |
| Bühler, FR | 1 |
1 review available for pindolol and Substance Withdrawal Syndrome
| Article | Year |
|---|---|
Pindolol--a beta-adrenoceptor blocking drug with partial agonist activity: clinical pharmacological considerations.
Topics: Adrenergic beta-Agonists; Animals; Heart Rate; Hemodynamics; Humans; Lung; Pindolol; Substance Withd | 1982 |
5 trials available for pindolol and Substance Withdrawal Syndrome
| Article | Year |
|---|---|
Comparison of withdrawal phenomena after propranolol, metoprolol, and pindolol.
Topics: Adult; Aged; Blood Pressure; Heart Rate; Humans; Hypertension; Isoproterenol; Metoprolol; Middle Age | 1982 |
Abrupt withdrawal of pindolol or metoprolol after chronic therapy.
Topics: Adult; Blood Pressure; Drug Hypersensitivity; Electrocardiography; Female; Heart Rate; Humans; Isopr | 1982 |
[Beta blocker treatment in alcohol withdrawal. A double-blind test with pindolol (Viskén)/placebo].
Topics: Adult; Aged; Alcoholism; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Pindolol; Plac | 1976 |
Withdrawal phenomena after atenolol and bopindolol: hormonal changes in normal volunteers.
Topics: Adrenergic beta-Antagonists; Atenolol; Blood Glucose; Catecholamines; Female; Hormones; Humans; Hydr | 1990 |
Withdrawal phenomena after atenolol and bopindolol: haemodynamic responses in healthy volunteers.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Blood Pressure; Exercise Test; Female; Heart Rate; Hor | 1990 |
8 other studies available for pindolol and Substance Withdrawal Syndrome
| Article | Year |
|---|---|
Elevation of beta-adrenergic receptor density in human lymphocytes after propranolol administration.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Blood Pressure; Female; Heart Rate; Hu | 1980 |
Withdrawal of beta-blocking drugs.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Heart Rate; Humans; Isoproterenol; Male; Middle Aged; | 1982 |
Comparison of withdrawal phenomena after propranolol, metoprolol and pindolol.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Heart Rate; Humans; Metoprolol; Middle Age | 1982 |
Beta-adrenoceptor blocking drugs and partial agonist activity. Is it clinically relevant?
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Asthma; Bradycardia; Cardiac Output; Heart Fa | 1983 |
Comparison of changes in the characteristics of beta-adrenoceptors and responsiveness of human circulating lymphocytes during and after chronic administration of pindolol and propranolol.
Topics: Adult; Cell Membrane; Cyclic AMP; Dihydroalprenolol; Humans; Isoproterenol; Lymphocytes; Male; Pindo | 1984 |
[Human pharmacology of carteolol].
Topics: Administration, Oral; Blood Platelets; Carteolol; Coronary Disease; Hemodynamics; Humans; Hypertensi | 1983 |
Cardiac hyper- and hyporesponsiveness after pindolol withdrawal.
Topics: Adult; Blood Pressure; Catecholamines; Female; Heart; Heart Rate; Humans; Isoproterenol; Male; Metop | 1982 |
Withdrawal of the long-acting beta blocker bopindolol is not associated with beta-adrenoceptor supersensitivity.
Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Blood Pressure; Female; Heart Rate; Humans; Male; M | 1986 |