pindolol has been researched along with Schizophrenia in 11 studies
Pindolol: A moderately lipophilic beta blocker (ADRENERGIC BETA-ANTAGONISTS). It is non-cardioselective and has intrinsic sympathomimetic actions, but little membrane-stabilizing activity. (From Martindale, The Extra Pharmocopoeia, 30th ed, p638)
pindolol : A member of the class of indols which is the 2-hydroxy-3-(isopropylamino)propyl ether derivative of 1H-indol-4-ol.
Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The binding of [125I]p-iodoclonidine to alpha-2, and/or [125I]iodopindolol to beta-1 and beta-2 adrenoceptors was measured in right prefrontal cortex (Brodmann's area 10) and right hippocampus from subjects with DSM-III-R diagnoses of major depression (n = 15) or schizophrenia (n = 8) as well as from control subjects (n = 20)." | 3.70 | Brain noradrenergic receptors in major depression and schizophrenia. ( Dilley, G; Klimek, V; Luker, SN; Meltzer, HY; Ordway, GA; Overholser, JC; Rajkowska, G; Stockmeier, CA, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (63.64) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gibson, CA | 1 |
| Stewart, JT | 1 |
| Tress, KH | 1 |
| Caudrey, DJ | 2 |
| Mehta, B | 1 |
| Kugler, BT | 1 |
| Gruzelier, JH | 1 |
| O'Connor, M | 1 |
| Klimek, V | 1 |
| Rajkowska, G | 1 |
| Luker, SN | 1 |
| Dilley, G | 1 |
| Meltzer, HY | 1 |
| Overholser, JC | 1 |
| Stockmeier, CA | 1 |
| Ordway, GA | 1 |
| Caspi, N | 1 |
| Modai, I | 1 |
| Barak, P | 1 |
| Waisbourd, A | 1 |
| Zbarsky, H | 1 |
| Hirschmann, S | 1 |
| Ritsner, M | 1 |
| Schoenen, J | 1 |
| Delwaide, PJ | 1 |
| Joyce, JN | 1 |
| Lexow, N | 1 |
| Kim, SJ | 1 |
| Artymyshyn, R | 1 |
| Senzon, S | 1 |
| Lawrence, D | 1 |
| Cassanova, MF | 1 |
| Kleinman, JE | 1 |
| Bird, ED | 1 |
| Winokur, A | 1 |
| Pandey, GN | 1 |
| Janicak, PG | 1 |
| Davis, JM | 1 |
| Reiter, S | 1 |
| Adler, L | 1 |
| Erle, S | 1 |
| Duncan, E | 1 |
| Meurice, E | 1 |
| Remy-Schmetz, J | 1 |
| Denys, WJ | 1 |
| Spruyt, L | 1 |
4 trials available for pindolol and Schizophrenia
| Article | Year |
|---|---|
Tactile-evoked potentials in schizophrenia. Interhemispheric transfer and drug effects.
Topics: Adult; Brain; Chronic Disease; Electroencephalography; Evoked Potentials, Somatosensory; Humans; Mal | 1983 |
Bilateral auditory acuity of schizophrenic patients: effects of repeated testing, time of day and medication.
Topics: Adult; Auditory Threshold; Clinical Trials as Topic; Dominance, Cerebral; Female; Functional Lateral | 1982 |
Pindolol augmentation in aggressive schizophrenic patients: a double-blind crossover randomized study.
Topics: Administration, Oral; Adult; Aged; Aggression; Cross-Over Studies; Double-Blind Method; Humans; Male | 2001 |
[Indications for beta-blockers in neurology].
Topics: Alcoholism; Antiparkinson Agents; Anxiety; Clinical Trials as Topic; Drug Therapy, Combination; Huma | 1978 |
7 other studies available for pindolol and Schizophrenia
| Article | Year |
|---|---|
Treatment of psychogenic polydipsia with pindolol.
Topics: Adrenergic beta-Antagonists; Antipsychotic Agents; Drinking Behavior; Humans; Hypotension; Male; Mid | 2006 |
Pindolol in schizophrenia.
Topics: Adult; Blood Pressure; Female; Humans; Male; Pindolol; Schizophrenia | 1981 |
Brain noradrenergic receptors in major depression and schizophrenia.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Affinity Labels; Aged; Autoradiograph | 1999 |
Distribution of beta-adrenergic receptor subtypes in human post-mortem brain: alterations in limbic regions of schizophrenics.
Topics: Adult; Autopsy; Autoradiography; Brain; Cell Membrane; Female; Humans; Imipramine; Iodine Radioisoto | 1992 |
Decreased beta-adrenergic receptors in the leukocytes of depressed patients.
Topics: Adult; Depressive Disorder; Dexamethasone; Humans; Hydrocortisone; Iodine Radioisotopes; Leukocytes; | 1987 |
Neuroleptic-induced akathisia treated with pindolol.
Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Humans; Male; Pindolol; Psychomotor Agitation; | 1987 |
[Preliminary trial of a beta-blocking agent (pindolol) in 3 schizophrenic patients and 3 non-psychotic psychiatric patients. Difference in sensitivity of heart rate].
Topics: Adult; Antisocial Personality Disorder; Bradycardia; Chronic Disease; Drug Evaluation; Heart Rate; H | 1974 |