pindolol has been researched along with Pregnancy in 64 studies
Pindolol: A moderately lipophilic beta blocker (ADRENERGIC BETA-ANTAGONISTS). It is non-cardioselective and has intrinsic sympathomimetic actions, but little membrane-stabilizing activity. (From Martindale, The Extra Pharmocopoeia, 30th ed, p638)
pindolol : A member of the class of indols which is the 2-hydroxy-3-(isopropylamino)propyl ether derivative of 1H-indol-4-ol.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a double blind study, 20 gravidas with pre-eclampsia were randomly allocated to treatment with either propranolol 120 mg/day or pindolol 15 mg/day for 7 days." | 9.07 | Flow velocity analysis of umbilical and uterine artery flow in pre-eclampsia treated with propranolol or pindolol. ( Holcberg, G; Insler, V; Katz, M; Meizner, I; Paran, E, 1992) |
| "29 women with pregnancy induced hypertension in the third trimester, 13 randomised to atenolol and 16 to pindolol." | 9.07 | Randomised controlled trial of atenolol and pindolol in human pregnancy: effects on fetal haemodynamics. ( Ingemarsson, I; Marsál, K; Montan, S; Sjöberg, NO, 1992) |
| "Thirty-two consecutive women with pregnancy-induced hypertension of early onset were randomly allocated to treatment with pindolol or methyldopa." | 9.06 | Management of pregnancy-induced hypertension with pindolol--comparative study with methyldopa. ( Anderman, S; Davidson, A; Ellenbogen, A; Grunstein, S; Jaschevatzky, O, 1986) |
| "Forty-four consecutive patients referred for treatment because of hypertension (greater than 150/90 mmHg) occurring during pregnancy were randomly allocated to one of two treatment groups, hydralazine alone (n = 21) or hydralazine combined with pindolol (n = 23)." | 9.06 | Treatment of hypertension during pregnancy with hydralazine monotherapy or with combined therapy with hydralazine and pindolol. ( Boner, G; Bott-Kanner, G; Friedman, S; Merlob, P; Nissenkorn, A; Ovadia, J; Paran, E; Reisner, S; Rosenfeld, J; Zmora, E, 1986) |
| "We investigated the effects of labetalol and pindolol on uterine, placental, and fetal hemodynamics following norepinephrine-induced maternal hypertension in a sheep model of increased placental vascular resistance." | 7.75 | Placental and fetal hemodynamics after labetalol or pindolol in a sheep model of increased placental vascular resistance and maternal hypertension. ( Acharya, G; Alahuhta, S; Erkinaro, T; Haapsamo, M; Kavasmaa, T; Mäkikallio, K; Ohtonen, P; Räsänen, J; Ylikauma, L, 2009) |
| "Nine patients taking oral doses of 10 mg/12 h rac-pindolol as part of their treatment for hypertension in pregnancy were recruited for the study." | 7.71 | Enantioselectivity in the steady-state pharmacokinetics and transplacental distribution of pindolol at delivery in pregnancy-induced hypertension. ( Da Cunha, SP; Gonçalves, PV; Lanchote, VL; Matthes, Ado C, 2002) |
| "The effect of a beta-adrenoceptor blocker, pindolol, on uteroplacental blood flow was determined in 10 women with pregnancy hypertension using an isotope technique giving a very low radiation dose." | 7.67 | Uteroplacental blood flow in pregnancy hypertension after the administration of a beta-adrenoceptor blocker, pindolol. ( Lewander, R; Lunell, NO; Nylund, L; Sarby, B; Wager, J, 1984) |
| " To determine whether this difference is due to pregnancy in general or is associated only with late pregnancy and to determine whether it persists in the postpartum period, we studied the interaction of l-isoproterenol with beta-adrenergic receptors in myometrial membranes obtained from nonpregnant (nulligravid) animals, pregnant (primigravid) animals at 0." | 7.67 | Pregnancy-induced changes in the interaction of guinea pig myometrial beta-adrenergic receptors with l-isoproterenol. ( Grogan, DM; Hatjis, CG, 1989) |
| "Two women with preeclampsia treated with pindolol and propranolol became profoundly hypertensive when indomethacin was added because of premature contractions." | 5.28 | Antagonism of antihypertensive drug therapy in pregnancy by indomethacin? ( Freedman, S; Hod, M; Ovadia, Y; Schoenfeld, A, 1989) |
| "Renal hypertension was induced by partial clamping of both renal arteries in female Wistar rats 4 weeks before pregnancy." | 5.27 | Acute haemodynamic effects of pindolol during pregnancy in experimental renal hypertension. ( Karlsson, K; Ljungblad, U; Lundgren, Y, 1984) |
| "Fifty-one women with pregnancy-induced hypertension (PIH) were randomly allocated to one of three treatment groups: A: hydralazine (13); B: hydralazine and propranolol (17); and C: hydralazine and pindolol (19)." | 5.08 | Beta-adrenergic blocking agents in the treatment of pregnancy-induced hypertension. ( Holzberg, G; Insler, V; Mazor, M; Paran, E; Zmora, E, 1995) |
| "To evaluate the short-term effects of intravenously given atenolol and pindolol on utero- and umbilicoplacental vascular impedance, fetal hemodynamics and cardiac function in patients suffering from pregnancy-induced hypertension." | 5.08 | Uterine and fetal hemodynamics and fetal cardiac function after atenolol and pindolol infusion. A randomized study. ( Jouppila, P; Räsänen, J, 1995) |
| "In a double blind study, 20 gravidas with pre-eclampsia were randomly allocated to treatment with either propranolol 120 mg/day or pindolol 15 mg/day for 7 days." | 5.07 | Flow velocity analysis of umbilical and uterine artery flow in pre-eclampsia treated with propranolol or pindolol. ( Holcberg, G; Insler, V; Katz, M; Meizner, I; Paran, E, 1992) |
| "29 women with pregnancy induced hypertension in the third trimester, 13 randomised to atenolol and 16 to pindolol." | 5.07 | Randomised controlled trial of atenolol and pindolol in human pregnancy: effects on fetal haemodynamics. ( Ingemarsson, I; Marsál, K; Montan, S; Sjöberg, NO, 1992) |
| "Thirty-two consecutive women with pregnancy-induced hypertension of early onset were randomly allocated to treatment with pindolol or methyldopa." | 5.06 | Management of pregnancy-induced hypertension with pindolol--comparative study with methyldopa. ( Anderman, S; Davidson, A; Ellenbogen, A; Grunstein, S; Jaschevatzky, O, 1986) |
| "Forty-four consecutive patients referred for treatment because of hypertension (greater than 150/90 mmHg) occurring during pregnancy were randomly allocated to one of two treatment groups, hydralazine alone (n = 21) or hydralazine combined with pindolol (n = 23)." | 5.06 | Treatment of hypertension during pregnancy with hydralazine monotherapy or with combined therapy with hydralazine and pindolol. ( Boner, G; Bott-Kanner, G; Friedman, S; Merlob, P; Nissenkorn, A; Ovadia, J; Paran, E; Reisner, S; Rosenfeld, J; Zmora, E, 1986) |
| " The incidence of severe hypertension was significantly lower when nifedipine (odds ratio, 0." | 5.05 | Comparative efficacy and safety of oral antihypertensive agents in pregnant women with chronic hypertension: a network metaanalysis. ( Bellos, I; Daskalakis, G; Loutradis, D; Papapanagiotou, A; Pergialiotis, V, 2020) |
| "We investigated the effects of labetalol and pindolol on uterine, placental, and fetal hemodynamics following norepinephrine-induced maternal hypertension in a sheep model of increased placental vascular resistance." | 3.75 | Placental and fetal hemodynamics after labetalol or pindolol in a sheep model of increased placental vascular resistance and maternal hypertension. ( Acharya, G; Alahuhta, S; Erkinaro, T; Haapsamo, M; Kavasmaa, T; Mäkikallio, K; Ohtonen, P; Räsänen, J; Ylikauma, L, 2009) |
| "Nine patients taking oral doses of 10 mg/12 h rac-pindolol as part of their treatment for hypertension in pregnancy were recruited for the study." | 3.71 | Enantioselectivity in the steady-state pharmacokinetics and transplacental distribution of pindolol at delivery in pregnancy-induced hypertension. ( Da Cunha, SP; Gonçalves, PV; Lanchote, VL; Matthes, Ado C, 2002) |
| " Fifteen patients with mild pre-eclampsia were chronically treated with oral pindolol." | 3.68 | The effect of acute and chronic antihypertensive therapy on maternal and fetoplacental Doppler velocimetry. ( Bjornsson, S; Cameron, AD; Fairlie, FM; Mathers, A; Walker, JJ, 1992) |
| "Receptor autoradiography using (-)-3-[125I]cyanopindolol and [3H]prazosin was used to study the distribution of beta and alpha-1 adrenoceptors in the rat uterus at early and midpregnancy." | 3.68 | Selective distribution of alpha-1 and beta adrenoceptors in pregnant rat uterus visualized by autoradiography. ( Legrand, C; Maltier, JP; Rigolot, C; Vivat, V, 1991) |
| "The effect of a beta-adrenoceptor blocker, pindolol, on uteroplacental blood flow was determined in 10 women with pregnancy hypertension using an isotope technique giving a very low radiation dose." | 3.67 | Uteroplacental blood flow in pregnancy hypertension after the administration of a beta-adrenoceptor blocker, pindolol. ( Lewander, R; Lunell, NO; Nylund, L; Sarby, B; Wager, J, 1984) |
| " To determine whether this difference is due to pregnancy in general or is associated only with late pregnancy and to determine whether it persists in the postpartum period, we studied the interaction of l-isoproterenol with beta-adrenergic receptors in myometrial membranes obtained from nonpregnant (nulligravid) animals, pregnant (primigravid) animals at 0." | 3.67 | Pregnancy-induced changes in the interaction of guinea pig myometrial beta-adrenergic receptors with l-isoproterenol. ( Grogan, DM; Hatjis, CG, 1989) |
| "During hypoxemia, fetal heart rate increased to baseline in the pindolol group and pulmonary vascular impedances increased in the labetalol group, with no changes in fetal cardiac outputs." | 1.39 | Fetal cardiac function after labetalol or pindolol for maternal hypertension in a sheep model of increased placental vascular resistance. ( Acharya, G; Erkinaro, T; Haapsamo, M; Kavasmaa, T; Mäkikallio, K; Räsänen, J, 2013) |
| "Two women with preeclampsia treated with pindolol and propranolol became profoundly hypertensive when indomethacin was added because of premature contractions." | 1.28 | Antagonism of antihypertensive drug therapy in pregnancy by indomethacin? ( Freedman, S; Hod, M; Ovadia, Y; Schoenfeld, A, 1989) |
| "Renal hypertension was induced by partial clamping of both renal arteries in female Wistar rats 4 weeks before pregnancy." | 1.27 | Acute haemodynamic effects of pindolol during pregnancy in experimental renal hypertension. ( Karlsson, K; Ljungblad, U; Lundgren, Y, 1984) |
| "Pindolol was administered with the food during the entire pregnancy period." | 1.27 | Hemodynamic changes after chronic pindolol administration in pregnant renal hypertensive rats. ( Karlsson, K; Ljungblad, U; Lundgren, Y, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 35 (54.69) | 18.7374 |
| 1990's | 23 (35.94) | 18.2507 |
| 2000's | 3 (4.69) | 29.6817 |
| 2010's | 1 (1.56) | 24.3611 |
| 2020's | 2 (3.13) | 2.80 |
| Authors | Studies |
|---|---|
| Bellos, I | 1 |
| Pergialiotis, V | 1 |
| Papapanagiotou, A | 1 |
| Loutradis, D | 1 |
| Daskalakis, G | 1 |
| Gonçalves, PVB | 1 |
| Moreira, FL | 1 |
| Benzi, JRL | 1 |
| Cavalli, RC | 2 |
| Duarte, G | 1 |
| Lanchote, VL | 3 |
| Erkinaro, T | 2 |
| Kavasmaa, T | 2 |
| Ylikauma, L | 1 |
| Mäkikallio, K | 2 |
| Haapsamo, M | 2 |
| Acharya, G | 2 |
| Ohtonen, P | 1 |
| Alahuhta, S | 1 |
| Räsänen, J | 3 |
| Gonçalves, PV | 2 |
| Matthes, Ado C | 1 |
| Da Cunha, SP | 2 |
| Lunell, NO | 1 |
| Nylund, L | 1 |
| Lewander, R | 1 |
| Sarby, B | 1 |
| Wager, J | 1 |
| Moses, JW | 1 |
| Borer, JS | 1 |
| Aguado, LI | 1 |
| Petrovic, SL | 1 |
| Ojeda, SR | 1 |
| Dubois, D | 2 |
| Petitcolas, J | 2 |
| Temperville, B | 1 |
| Klepper, A | 1 |
| Catherine, P | 1 |
| Ingemarsson, I | 3 |
| Liedholm, H | 1 |
| Montan, S | 2 |
| Westgren, M | 1 |
| Melander, A | 1 |
| Whitsett, JA | 3 |
| Manton, MA | 2 |
| Darovec-Beckerman, C | 2 |
| Adams, K | 1 |
| Adams, KG | 1 |
| Moore, JJ | 2 |
| Di Renzo, GC | 1 |
| Venincasa, MD | 1 |
| Bleasdale, JE | 1 |
| Frishman, WH | 1 |
| Schatz, IJ | 1 |
| Lundgren, Y | 2 |
| Karlsson, K | 2 |
| Ljungblad, U | 2 |
| Paran, E | 3 |
| Holzberg, G | 1 |
| Mazor, M | 1 |
| Zmora, E | 2 |
| Insler, V | 2 |
| Nwosu, UC | 1 |
| Rice, PJ | 1 |
| Hurd, WW | 1 |
| Gauvin, JM | 1 |
| Dombrowski, MP | 1 |
| Hayashi, RH | 1 |
| Bian, X | 1 |
| Seidler, FJ | 2 |
| Olsen, C | 1 |
| Raymond, JR | 1 |
| Slotkin, TA | 3 |
| Jouppila, P | 1 |
| Pantuck, CB | 1 |
| Smiley, RM | 1 |
| Ohashi, T | 1 |
| Hashimoto, S | 1 |
| Morikawa, K | 1 |
| Kato, H | 1 |
| Ito, Y | 1 |
| Asano, M | 1 |
| Azuma, H | 1 |
| Lécrivain, JL | 1 |
| Cohen-Tannoudji, J | 2 |
| Robin, MT | 1 |
| Coudouel, N | 1 |
| Legrand, C | 3 |
| Maltier, JP | 3 |
| Ovcharov, R | 1 |
| Mikhaĭlova, S | 1 |
| Monnier, JC | 1 |
| Honore, P | 1 |
| Lanciaux, B | 1 |
| Boulogne, M | 1 |
| Ricker, K | 1 |
| Haass, A | 1 |
| Glötzner, F | 1 |
| Meizner, I | 1 |
| Katz, M | 1 |
| Holcberg, G | 1 |
| Mooij, PN | 1 |
| Nijhuis, JG | 1 |
| Jongsma, HW | 1 |
| Menssen, JJ | 1 |
| Walker, JJ | 1 |
| Mathers, A | 1 |
| Bjornsson, S | 1 |
| Cameron, AD | 1 |
| Fairlie, FM | 1 |
| Marsál, K | 1 |
| Sjöberg, NO | 1 |
| Vivat, V | 2 |
| Heilmann, J | 1 |
| Kudlacz, EM | 1 |
| Spencer, JR | 1 |
| Watanabe, K | 1 |
| Shibata, A | 1 |
| Wakabayashi, H | 1 |
| Shimada, K | 1 |
| Tsuchihashi, H | 1 |
| Kinami, J | 1 |
| Nagatomo, T | 1 |
| Rigolot, C | 1 |
| Montero, D | 1 |
| De Felipe, MC | 1 |
| Del Río, J | 1 |
| Druse, MJ | 1 |
| Kuo, A | 1 |
| Tajuddin, N | 1 |
| Mynlieff, M | 1 |
| Curella, P | 1 |
| Zahniser, NR | 1 |
| Gerhardt, GA | 1 |
| Seiger, A | 1 |
| Dunwiddie, TV | 1 |
| Marchetti, B | 2 |
| Fortier, MA | 1 |
| Poyet, P | 1 |
| Folléa, N | 1 |
| Pelletier, G | 1 |
| Labrie, F | 2 |
| Navarro, HA | 1 |
| McCook, EC | 1 |
| Wigal, SB | 1 |
| Amsel, A | 1 |
| Wilcox, RE | 1 |
| el Alj, A | 1 |
| Breuiller, M | 2 |
| Jolivet, A | 1 |
| Ferre, F | 2 |
| Germain, G | 1 |
| Hatjis, CG | 3 |
| Grogan, DM | 1 |
| Ruiz, G | 1 |
| Hamon, M | 1 |
| Vergé, D | 1 |
| Egarter, C | 1 |
| Meisner, W | 1 |
| Kroboth, WK | 1 |
| Grünberger, W | 1 |
| Schoenfeld, A | 1 |
| Freedman, S | 1 |
| Hod, M | 1 |
| Ovadia, Y | 1 |
| Crews, A | 1 |
| Snell, K | 1 |
| Evans, CA | 1 |
| Handberg, GM | 1 |
| Davis, EA | 1 |
| Hall, S | 1 |
| Molenaar, P | 1 |
| Summers, RJ | 1 |
| Pennefather, JN | 1 |
| Kawecka-Jaszcz, K | 1 |
| Skoczeń, M | 1 |
| Dattel, BJ | 1 |
| Lam, F | 1 |
| Roberts, JM | 1 |
| Ellenbogen, A | 1 |
| Jaschevatzky, O | 1 |
| Davidson, A | 1 |
| Anderman, S | 1 |
| Grunstein, S | 1 |
| Riant, P | 1 |
| Urien, S | 1 |
| Albengres, E | 1 |
| Duche, JC | 1 |
| Tillement, JP | 1 |
| Palmer, KC | 1 |
| Grammas, P | 1 |
| Rouot, B | 1 |
| Leroy, MJ | 1 |
| Blot, P | 1 |
| Kaplan, L | 1 |
| Adaikan, PG | 1 |
| Arulkumaran, S | 1 |
| Kottegoda, SR | 1 |
| Rosenfeld, J | 1 |
| Bott-Kanner, G | 1 |
| Boner, G | 1 |
| Nissenkorn, A | 1 |
| Friedman, S | 1 |
| Ovadia, J | 1 |
| Merlob, P | 1 |
| Reisner, S | 1 |
| Seedat, YK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Non-steroidal Anti-inflammatory Use on Blood Pressure in Women With Hypertensive Disorders of Pregnancy: A Randomized Open Label Trial[NCT03824119] | Phase 4 | 200 participants (Anticipated) | Interventional | 2018-12-11 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for pindolol and Pregnancy
| Article | Year |
|---|---|
Comparative efficacy and safety of oral antihypertensive agents in pregnant women with chronic hypertension: a network metaanalysis.
Topics: Abruptio Placentae; Amlodipine; Antihypertensive Agents; Atenolol; Cesarean Section; Chronic Disease | 2020 |
Beta-adrenergic antagonists in the treatment of patients with heart disease.
Topics: Acebutolol; Adrenergic beta-Agonists; Alprenolol; Animals; Arrhythmias, Cardiac; Bronchial Spasm; Ca | 1981 |
Drug therapy. Pindolol: a new beta-adrenoceptor antagonist with partial agonist activity.
Topics: Animals; Arrhythmias, Cardiac; Chemical Phenomena; Chemistry; Child; Coronary Disease; Female; Human | 1983 |
Intracranial pressure and fetal heart rate in a hydrocephalic fetus during labor.
Topics: Adult; Drainage; Female; Heart Rate, Fetal; Humans; Hydralazine; Hydrocephalus; Intracranial Pressur | 1992 |
[Beta-blockaders in the treatment of hypertension in pregnancy].
Topics: Adrenergic beta-Antagonists; Atenolol; Drug Evaluation; Female; Humans; Hypertension; Metoprolol; Ox | 1985 |
7 trials available for pindolol and Pregnancy
| Article | Year |
|---|---|
Beta-adrenergic blocking agents in the treatment of pregnancy-induced hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Blood Glucose; Blood Pressure; Drug Therapy, Combination; Female | 1995 |
Uterine and fetal hemodynamics and fetal cardiac function after atenolol and pindolol infusion. A randomized study.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Atenolol; Female; Fetal Heart; Hemodyna | 1995 |
Flow velocity analysis of umbilical and uterine artery flow in pre-eclampsia treated with propranolol or pindolol.
Topics: Adult; Arteries; Blood Flow Velocity; Double-Blind Method; Female; Humans; Pindolol; Placenta; Pre-E | 1992 |
Randomised controlled trial of atenolol and pindolol in human pregnancy: effects on fetal haemodynamics.
Topics: Atenolol; Blood Pressure; Double-Blind Method; Female; Fetus; Heart Rate; Hemodynamics; Humans; Hype | 1992 |
Effect of beta-receptor blockers on uterine contractility in a puerperal model.
Topics: Adrenergic beta-Antagonists; Double-Blind Method; Female; Humans; Pindolol; Postpartum Period; Pregn | 1989 |
Management of pregnancy-induced hypertension with pindolol--comparative study with methyldopa.
Topics: Adult; Female; Fetus; Humans; Hypertension; Methyldopa; Pindolol; Pregnancy; Pregnancy Complications | 1986 |
Treatment of hypertension during pregnancy with hydralazine monotherapy or with combined therapy with hydralazine and pindolol.
Topics: Adult; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Pindolo | 1986 |
52 other studies available for pindolol and Pregnancy
| Article | Year |
|---|---|
Nonrelevant Pharmacokinetic Drug-Drug Interaction Between Furosemide and Pindolol Enantiomers in Hypertensive Parturient Women.
Topics: Administration, Oral; Antihypertensive Agents; Diuretics; Drug Interactions; Female; Furosemide; Hum | 2020 |
Placental and fetal hemodynamics after labetalol or pindolol in a sheep model of increased placental vascular resistance and maternal hypertension.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Anima | 2009 |
Fetal cardiac function after labetalol or pindolol for maternal hypertension in a sheep model of increased placental vascular resistance.
Topics: Animals; Antihypertensive Agents; Female; Fetal Heart; Hypertension, Pregnancy-Induced; Hypoxia; Lab | 2013 |
Enantioselectivity in the steady-state pharmacokinetics and transplacental distribution of pindolol at delivery in pregnancy-induced hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Female; Humans; Hypertension; Pindolol; | 2002 |
Determination of pindolol enantiomers in amniotic fluid and breast milk by high-performance liquid chromatography: applications to pharmacokinetics in pregnant and lactating women.
Topics: Adult; Amniotic Fluid; Antihypertensive Agents; Female; Humans; Lactation; Milk, Human; Pindolol; Pr | 2007 |
Uteroplacental blood flow in pregnancy hypertension after the administration of a beta-adrenoceptor blocker, pindolol.
Topics: Cyclic AMP; Female; Hemodynamics; Humans; Hypertension; Pindolol; Placenta; Pregnancy; Pregnancy Com | 1984 |
Ovarian beta-adrenergic receptors during the onset of puberty: characterization, distribution, and coupling to steroidogenic responses.
Topics: Adrenergic beta-Agonists; Androgens; Animals; Estrus; Ethanolamines; Female; Granulosa Cells; Isopro | 1982 |
Treatment of hypertension in pregnancy with beta-adrenoceptor antagonists.
Topics: Abnormalities, Drug-Induced; Acebutolol; Adrenergic beta-Antagonists; Adult; Apgar Score; Atenolol; | 1982 |
Fetal heart rate during treatment of maternal hypertension with beta-adrenergic antagonists. A preliminary report.
Topics: Adrenergic beta-Antagonists; Atenolol; Female; Fetal Heart; Heart Rate; Humans; Hypertension; Pindol | 1984 |
II. Beta-adrenergic receptors and catecholamine sensitive adenylate cyclase in the developing rat lung.
Topics: Adenylyl Cyclases; Animals; Benzyl Alcohols; Catecholamines; Cell Membrane; Dihydroalprenolol; Enzym | 1981 |
beta-Adrenergic receptors in the developing rabbit lung.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Dihydroalprenolol; Female; Lung; Pindolol; Pregnancy; Rab | 1981 |
The beta-adrenergic receptor in human placenta: receptor subtype analysis (beta 1 and beta 2) and partial characterization of the solubilized receptor.
Topics: Chromatography, Gel; Dihydroalprenolol; Female; Humans; Iodine Radioisotopes; Pindolol; Placenta; Pr | 1981 |
The identification and characterization of beta-adrenergic receptors in human amnion tissue.
Topics: Amnion; Binding, Competitive; Cyclic AMP; Ethanolamines; Female; Humans; Iodocyanopindolol; Isoprote | 1984 |
Orthostatic hypotension: diagnosis and treatment.
Topics: Blood Pressure; Diagnosis, Differential; Dizziness; Female; Fludrocortisone; Humans; Hypotension, Or | 1984 |
Acute haemodynamic effects of pindolol during pregnancy in experimental renal hypertension.
Topics: Animals; Blood Pressure; Cardiac Output; Female; Heart Rate; Hemodynamics; Hypertension, Renal; Ovar | 1984 |
Hemodynamic changes after chronic pindolol administration in pregnant renal hypertensive rats.
Topics: Animals; Blood Pressure; Body Weight; Cardiac Output; Female; Hemodynamics; Hypertension, Renal; Mat | 1983 |
Beta-adrenoceptor changes in mononuclear leukocytes during pregnancy.
Topics: Adult; Cyclic AMP; Female; Humans; Leukocytes, Mononuclear; Pindolol; Pregnancy; Radioligand Assay; | 1995 |
Cocaine selectively inhibits beta-adrenergic receptor binding in pregnant human myometrium.
Topics: Adrenergic beta-Antagonists; Binding, Competitive; Cocaine; Dihydroergotoxine; Dose-Response Relatio | 1993 |
Effects of fetal dexamethasone exposure on postnatal control of cardiac adenylate cyclase: beta-adrenergic receptor coupling to Gs regulatory protein.
Topics: Adenylyl Cyclases; Animals; Dexamethasone; Enzyme Activation; Female; GTP-Binding Proteins; Heart; I | 1993 |
Effect of cesarean delivery on perioperative regulation of the beta-adrenergic receptor system of human lymphocytes.
Topics: Abdomen; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Alprostadil; Anesthesia, Obst | 1996 |
Potent inhibition of spontaneous rhythmic contraction by a novel beta 2-adrenoceptor agonist, HSR-81, in pregnant rat uterus.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; | 1996 |
Molecular mechanisms of adenylyl cyclase desensitization in pregnant rat myometrium following in vivo administration of the beta-adrenergic agonist, isoproterenol.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Colforsin; Drug T | 1998 |
[Effect of beta-adrenergic blockaders on the uterine musculature of rats].
Topics: Adrenergic beta-Antagonists; Animals; Castration; Estradiol; Estrogens; Estrus; Female; Pindolol; Pr | 1977 |
[beta-blockers and high risk pregnancies. Viewpoint of the nephrologist and the obstetrician].
Topics: Acebutolol; Adrenergic beta-Antagonists; Female; Humans; Hypertension; Pindolol; Pregnancy; Pregnanc | 1978 |
[Value of hydralazine-beta blockader association in hypertension of pregnancy].
Topics: Adrenergic beta-Antagonists; Adult; Drug Therapy, Combination; Female; Fetus; Humans; Hydralazine; H | 1978 |
Fenoterol precipitating myotonia in a minimally affected case of recessive myotonia congenita.
Topics: Adult; Ethanolamines; Female; Fenoterol; Heterozygote; Humans; Male; Middle Aged; Myotonia Congenita | 1978 |
The effect of acute and chronic antihypertensive therapy on maternal and fetoplacental Doppler velocimetry.
Topics: Blood Pressure; Brachial Artery; Female; Fetus; Humans; Hypertension; Infant, Newborn; Nicardipine; | 1992 |
Regulation by progesterone of the high-affinity state of myometrial beta-adrenergic receptor and of adenylate cyclase activity in the pregnant rat.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Female; Iodocyanopindolol; Isoproterenol; Kinetics; Mifep | 1991 |
Postnatal alterations in beta-adrenergic receptor binding in rat brain regions after continuous prenatal exposure to propranolol via maternal infusion.
Topics: Animals; Body Weight; Brain; Brain Stem; Cerebellum; Female; Infusions, Intravenous; Maternal-Fetal | 1991 |
Changes in alpha 1- and beta 1-adrenergic receptors and calcium ion binding sites in the fetal myocardium of spontaneously hypertensive rats (SHR).
Topics: Animals; Binding Sites; Calcium; Catecholamines; Female; Fetal Heart; Hypertension; Iodocyanopindolo | 1991 |
Selective distribution of alpha-1 and beta adrenoceptors in pregnant rat uterus visualized by autoradiography.
Topics: Animals; Autoradiography; Female; Iodocyanopindolol; Pindolol; Prazosin; Pregnancy; Pregnancy, Anima | 1991 |
Acute or chronic antidepressants do not modify [125I]cyanopindolol binding to 5-HT1B receptors in rat brain.
Topics: Animals; Antidepressive Agents, Tricyclic; Biogenic Monoamines; Brain; Clomipramine; Female; Iodine | 1991 |
Effects of in utero ethanol exposure on the developing serotonergic system.
Topics: Animals; Animals, Newborn; Brain Stem; Cerebral Cortex; Chromatography, High Pressure Liquid; Ethano | 1991 |
Regulation of adrenergic receptors in intraocular hippocampal transplants: role of noradrenergic innervation.
Topics: Adrenergic alpha-Antagonists; Animals; Autoradiography; Biogenic Amines; Chromatography, High Pressu | 1990 |
Beta-adrenergic receptors in the rat mammary gland during pregnancy and lactation: characterization, distribution, and coupling to adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Autoradiography; Cytosol; Female; Gonadal Steroid Hormones; Kinetics; La | 1990 |
Hormonal regulation of beta-adrenergic receptors in the rat mammary gland during the estrous cycle and lactation: role of sex steroids and prolactin.
Topics: Animals; Estrus; Female; Gonadal Steroid Hormones; Hormones; Lactation; Mammary Glands, Animal; Memb | 1990 |
Fetal nicotine exposure produces postnatal up-regulation of adenylate cyclase activity in peripheral tissues.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Colforsin; Female; Fetal Resorption; Isoproterenol; Kidne | 1990 |
Fetal ethanol exposure diminishes hippocampal beta-adrenergic receptor density while sparing muscarinic receptors during development.
Topics: Animals; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Heart; Hippocampus; Iodine Radioisotopes | 1990 |
Beta 2-adrenoceptor response in the rat uterus at the end of gestation and after induction of labor with RU 486.
Topics: Albuterol; Animals; Epinephrine; Female; In Vitro Techniques; Iodine Radioisotopes; Iodocyanopindolo | 1989 |
Pregnancy-induced changes in the interaction of guinea pig myometrial beta-adrenergic receptors with l-isoproterenol.
Topics: Adrenergic beta-Antagonists; Animals; Female; Guanosine Triphosphate; Guinea Pigs; Isoproterenol; My | 1989 |
Chronic phenytoin treatment decreases GABAA but not beta-adrenoceptors in the cerebellum of young rats.
Topics: Adrenergic beta-Antagonists; Animals; Autoradiography; Cerebellum; Female; Flunitrazepam; Kinetics; | 1989 |
Antagonism of antihypertensive drug therapy in pregnancy by indomethacin?
Topics: Adult; Antihypertensive Agents; Blood Pressure; Female; Humans; Indomethacin; Obstetric Labor, Prema | 1989 |
Regulation of guinea pig myometrial beta-adrenoreceptors by guanosine triphosphate and magnesium ion.
Topics: Animals; Female; Guanosine Triphosphate; Guinea Pigs; Iodine Radioisotopes; Isoproterenol; Magnesium | 1988 |
Characterization of rat liver beta-adrenoceptors during perinatal development as determined by [125I]-iodopindolol radioligand binding assays.
Topics: Animals; Cell Membrane; Female; Iodine Radioisotopes; Kinetics; Liver; Pindolol; Pregnancy; Radiolig | 1988 |
Beta-adrenoceptors in circular and longitudinal myometrial membranes and in lung membranes from dioestrous and post-partum guinea-pigs.
Topics: Animals; Autoradiography; Diestrus; Extraembryonic Membranes; Female; Guinea Pigs; Lung; Myometrium; | 1988 |
beta-Adrenergic-receptor and adenylate cyclase properties in pregnant and nonpregnant guinea pig myometrium.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Binding Sites; Binding, Competitive; Female; G | 1985 |
Failure to demonstrate decreased beta-adrenergic receptor concentration or decreased agonist efficacy in term or preterm human parturition.
Topics: Adrenergic beta-Agonists; Binding, Competitive; Female; Humans; Iodocyanopindolol; Isoproterenol; La | 1986 |
High plasma protein binding as a parameter in the selection of betablockers for lactating women.
Topics: Acebutolol; Adrenergic beta-Antagonists; Blood Proteins; Female; Humans; Hypertension; Lactation; Mi | 1986 |
Beta-adrenergic regulation of secretion from Clara cell adenomas of the mouse lung.
Topics: Adenoma; Animals; Cytoplasmic Granules; Female; Iodocyanopindolol; Isoproterenol; Lung Neoplasms; Mi | 1987 |
Adrenergic receptors in inner and outer layers of human myometrium near term: characterization of beta-adrenergic receptor sites by [125I]-iodocyanopindolol binding.
Topics: Binding Sites; Female; Humans; Iodocyanopindolol; Myometrium; Pindolol; Pregnancy; Receptors, Adrene | 1987 |
Effect of a beta-adrenoceptor antagonist, pindolol, on human uterine smooth muscle.
Topics: Adult; Blood Pressure; Female; Humans; Hypertension; In Vitro Techniques; Myometrium; Pindolol; Preg | 1987 |
Prindolol in the management of hypertension.
Topics: Adult; Antihypertensive Agents; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Pindo | 1974 |