pindolol has been researched along with Pre-Eclampsia in 6 studies
Pindolol: A moderately lipophilic beta blocker (ADRENERGIC BETA-ANTAGONISTS). It is non-cardioselective and has intrinsic sympathomimetic actions, but little membrane-stabilizing activity. (From Martindale, The Extra Pharmocopoeia, 30th ed, p638)
pindolol : A member of the class of indols which is the 2-hydroxy-3-(isopropylamino)propyl ether derivative of 1H-indol-4-ol.
Pre-Eclampsia: A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a double blind study, 20 gravidas with pre-eclampsia were randomly allocated to treatment with either propranolol 120 mg/day or pindolol 15 mg/day for 7 days." | 9.07 | Flow velocity analysis of umbilical and uterine artery flow in pre-eclampsia treated with propranolol or pindolol. ( Holcberg, G; Insler, V; Katz, M; Meizner, I; Paran, E, 1992) |
| "Two women with preeclampsia treated with pindolol and propranolol became profoundly hypertensive when indomethacin was added because of premature contractions." | 5.28 | Antagonism of antihypertensive drug therapy in pregnancy by indomethacin? ( Freedman, S; Hod, M; Ovadia, Y; Schoenfeld, A, 1989) |
| "In a double blind study, 20 gravidas with pre-eclampsia were randomly allocated to treatment with either propranolol 120 mg/day or pindolol 15 mg/day for 7 days." | 5.07 | Flow velocity analysis of umbilical and uterine artery flow in pre-eclampsia treated with propranolol or pindolol. ( Holcberg, G; Insler, V; Katz, M; Meizner, I; Paran, E, 1992) |
| " The incidence of severe hypertension was significantly lower when nifedipine (odds ratio, 0." | 5.05 | Comparative efficacy and safety of oral antihypertensive agents in pregnant women with chronic hypertension: a network metaanalysis. ( Bellos, I; Daskalakis, G; Loutradis, D; Papapanagiotou, A; Pergialiotis, V, 2020) |
| " Fifteen patients with mild pre-eclampsia were chronically treated with oral pindolol." | 3.68 | The effect of acute and chronic antihypertensive therapy on maternal and fetoplacental Doppler velocimetry. ( Bjornsson, S; Cameron, AD; Fairlie, FM; Mathers, A; Walker, JJ, 1992) |
| "Two women with preeclampsia treated with pindolol and propranolol became profoundly hypertensive when indomethacin was added because of premature contractions." | 1.28 | Antagonism of antihypertensive drug therapy in pregnancy by indomethacin? ( Freedman, S; Hod, M; Ovadia, Y; Schoenfeld, A, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Bellos, I | 1 |
| Pergialiotis, V | 1 |
| Papapanagiotou, A | 1 |
| Loutradis, D | 1 |
| Daskalakis, G | 1 |
| Monnier, JC | 1 |
| Honore, P | 1 |
| Lanciaux, B | 1 |
| Boulogne, M | 1 |
| Meizner, I | 1 |
| Paran, E | 1 |
| Katz, M | 1 |
| Holcberg, G | 1 |
| Insler, V | 1 |
| Walker, JJ | 1 |
| Mathers, A | 1 |
| Bjornsson, S | 1 |
| Cameron, AD | 1 |
| Fairlie, FM | 1 |
| Schoenfeld, A | 1 |
| Freedman, S | 1 |
| Hod, M | 1 |
| Ovadia, Y | 1 |
| Seedat, YK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Non-steroidal Anti-inflammatory Use on Blood Pressure in Women With Hypertensive Disorders of Pregnancy: A Randomized Open Label Trial[NCT03824119] | Phase 4 | 200 participants (Anticipated) | Interventional | 2018-12-11 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for pindolol and Pre-Eclampsia
| Article | Year |
|---|---|
Comparative efficacy and safety of oral antihypertensive agents in pregnant women with chronic hypertension: a network metaanalysis.
Topics: Abruptio Placentae; Amlodipine; Antihypertensive Agents; Atenolol; Cesarean Section; Chronic Disease | 2020 |
1 trial available for pindolol and Pre-Eclampsia
| Article | Year |
|---|---|
Flow velocity analysis of umbilical and uterine artery flow in pre-eclampsia treated with propranolol or pindolol.
Topics: Adult; Arteries; Blood Flow Velocity; Double-Blind Method; Female; Humans; Pindolol; Placenta; Pre-E | 1992 |
4 other studies available for pindolol and Pre-Eclampsia
| Article | Year |
|---|---|
[Value of hydralazine-beta blockader association in hypertension of pregnancy].
Topics: Adrenergic beta-Antagonists; Adult; Drug Therapy, Combination; Female; Fetus; Humans; Hydralazine; H | 1978 |
The effect of acute and chronic antihypertensive therapy on maternal and fetoplacental Doppler velocimetry.
Topics: Blood Pressure; Brachial Artery; Female; Fetus; Humans; Hypertension; Infant, Newborn; Nicardipine; | 1992 |
Antagonism of antihypertensive drug therapy in pregnancy by indomethacin?
Topics: Adult; Antihypertensive Agents; Blood Pressure; Female; Humans; Indomethacin; Obstetric Labor, Prema | 1989 |
Prindolol in the management of hypertension.
Topics: Adult; Antihypertensive Agents; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Pindo | 1974 |