pindolol has been researched along with Myocardial Ischemia in 6 studies
Pindolol: A moderately lipophilic beta blocker (ADRENERGIC BETA-ANTAGONISTS). It is non-cardioselective and has intrinsic sympathomimetic actions, but little membrane-stabilizing activity. (From Martindale, The Extra Pharmocopoeia, 30th ed, p638)
pindolol : A member of the class of indols which is the 2-hydroxy-3-(isopropylamino)propyl ether derivative of 1H-indol-4-ol.
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oxygen-derived free radicals contribute to tissue injury during myocardial ischemia, and propranolol or pindolol do not possess free radical scavenging properties relevant for cardioprotection in a repetitive coronary occlusion model in isolated rabbit hearts." | 3.68 | Free radical scavenging properties of beta-adrenoceptor blockers are not relevant for cardioprotection in isolated rabbit hearts. ( Klaus, W; Rösen, R; Rump, AF, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ihl-Vahl, R | 1 |
| Marquetant, R | 1 |
| Bremerich, J | 1 |
| Strasser, RH | 1 |
| Rump, AF | 2 |
| Rösen, R | 2 |
| Klaus, W | 2 |
| Elnatan, J | 1 |
| Molenaar, P | 1 |
| Rosenfeldt, FL | 1 |
| Summers, RJ | 1 |
| Picke, D | 1 |
| Brodde, OE | 1 |
| Vogelsang, M | 1 |
| Broede, A | 1 |
| Michel-Reher, M | 1 |
| Beisenbusch-Schäfer, E | 1 |
| Hakim, K | 1 |
| Zerkowski, HR | 1 |
| Schrör, K | 1 |
| Zimmermann, KC | 1 |
| Tannhäuser, R | 1 |
6 other studies available for pindolol and Myocardial Ischemia
| Article | Year |
|---|---|
Regulation of beta-adrenergic receptors in acute myocardial ischemia: subtype-selective increase of mRNA specific for beta 1-adrenergic receptors.
Topics: Acute Disease; Animals; Base Sequence; Cell Membrane; DNA Primers; Gene Expression Regulation; Iodin | 1995 |
Free radical scavenging properties of beta-adrenoceptor blockers are not relevant for cardioprotection in isolated rabbit hearts.
Topics: Adrenergic beta-Antagonists; Animals; Coronary Circulation; Electric Stimulation; Fluorescence; Free | 1993 |
Autoradiographic localization and quantitation of beta 1- and beta 2-adrenoceptors in the human atrioventricular conducting system: a comparison of patients with idiopathic dilated cardiomyopathy and ischemic heart disease.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Atrioventricular Node; Binding, Competitive; Bundle of His | 1994 |
Effects of propranolol, pindolol and carteolol on acute regional myocardial ischemia in isolated rabbit hearts.
Topics: Adrenergic beta-Antagonists; Animals; Carteolol; Catecholamines; Coronary Circulation; Electric Stim | 1993 |
Diminished responsiveness of Gs-coupled receptors in severely failing human hearts: no difference in dilated versus ischemic cardiomyopathy.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adult; Cardiomyopathy, Dilated; Female; GTP-Binding Pro | 1998 |
Augmented myocardial ischaemia by nicotine--mechanisms and their possible significance.
Topics: Adrenergic beta-Antagonists; Animals; Biomarkers; Catecholamines; Cyclooxygenase 2; Epoprostenol; He | 1998 |