pindolol has been researched along with Multiple Sclerosis in 3 studies
Pindolol: A moderately lipophilic beta blocker (ADRENERGIC BETA-ANTAGONISTS). It is non-cardioselective and has intrinsic sympathomimetic actions, but little membrane-stabilizing activity. (From Martindale, The Extra Pharmocopoeia, 30th ed, p638)
pindolol : A member of the class of indols which is the 2-hydroxy-3-(isopropylamino)propyl ether derivative of 1H-indol-4-ol.
Multiple Sclerosis: An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 3 (100.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Zoukos, Y | 1 |
Thomaides, T | 1 |
Mathias, CJ | 1 |
Cuzner, ML | 1 |
Karaszewski, JW | 2 |
Reder, AT | 2 |
Anlar, B | 1 |
Kim, WC | 1 |
Arnason, BG | 2 |
Maselli, R | 1 |
Brown, M | 1 |
3 other studies available for pindolol and Multiple Sclerosis
Article | Year |
---|---|
High beta-adrenoceptor density on peripheral blood mononuclear cells in progressive multiple sclerosis: a manifestation of autonomic dysfunction?
Topics: Adult; Aged; Autonomic Nervous System; Autonomic Nervous System Diseases; Clonidine; Epinephrine; Fe | 1994 |
Increased lymphocyte beta-adrenergic receptor density in progressive multiple sclerosis is specific for the CD8+, CD28- suppressor cell.
Topics: Adult; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Autoimmune Diseases; CD28 Antigens; CD | 1991 |
Sympathetic skin responses are decreased and lymphocyte beta-adrenergic receptors are increased in progressive multiple sclerosis.
Topics: Adult; Binding, Competitive; Cyclic AMP; Electric Stimulation; Female; Humans; Male; Membrane Potent | 1990 |