Page last updated: 2024-11-02

pindolol and Intraocular Pressure

pindolol has been researched along with Intraocular Pressure in 25 studies

Pindolol: A moderately lipophilic beta blocker (ADRENERGIC BETA-ANTAGONISTS). It is non-cardioselective and has intrinsic sympathomimetic actions, but little membrane-stabilizing activity. (From Martindale, The Extra Pharmocopoeia, 30th ed, p638)
pindolol : A member of the class of indols which is the 2-hydroxy-3-(isopropylamino)propyl ether derivative of 1H-indol-4-ol.

Intraocular Pressure: The pressure of the fluids in the eye.

Research Excerpts

ExcerptRelevanceReference
"A pilot study on 10 consecutive patients with newly diagnosed glaucoma and a randomised double-blind study on 18 patients with glaucoma were carried out to investigate the effect of pindolol, a beta-adrenergic blocking agent, on the intraocular pressure (IOP) in patients with glaucoma."9.05Effect of pindolol on intraocular pressure in glaucoma: pilot study and a randomised comparison with timolol. ( Andréasson, S; Jensen, KM, 1983)
"5% pindolol eye drops on intraocular pressure."9.05The effect of 0.25% and 0.5% pindolol in intraocular pressure in normal human volunteers. ( Edgar, DF; Stewart-Jones, JH; Turner, P; Tyas, C, 1981)
"Pindolol, a strong beta-adrenergic blocking agent, instilled into the conjunctival sac of normal and glaucomatous eyes, produced a significant drop in intraocular pressure."9.04Effect of pindolol on intraocular pressure. ( Bonomi, I; Steindler, P, 1975)
"Falls in intraocular pressure were significantly correlated with resting intraocular pressure."6.65A noninvasive tonometer in the measurement of the effects of pindolol and timolol on intraocular pressure in normal subjects. ( Edgar, DF; Rowley, S; Staunton, JE; Stewart-Jones, JH; Tosch, A; Turner, P, 1981)
"The response of two ophthalmic betablockers, Timolol (without ISA) and Pindolol (with marked ISA), on IOP and tonographic outflow facility was investigated in a single-blind clinical study on 20 patients with glaucoma or ocular hypertension."5.06The effect of betablockers with and without ISA on tonographic outflow facility. ( Diestelhorst, M; Krieglstein, GK, 1989)
"In a prospective, multicenter, randomized, double-masked study of glaucoma patients, visual fields, intraocular pressures, blood pressures, and pulse rates were measured after a 4-week wash-out period and after three and six months of treatment with either pindolol 1% or timolol 0."5.06Influence of pindolol and timolol treatment on the visual fields of glaucoma patients. ( Flammer, J; Gloor, B; Robert, Y, 1986)
"A pilot study on 10 consecutive patients with newly diagnosed glaucoma and a randomised double-blind study on 18 patients with glaucoma were carried out to investigate the effect of pindolol, a beta-adrenergic blocking agent, on the intraocular pressure (IOP) in patients with glaucoma."5.05Effect of pindolol on intraocular pressure in glaucoma: pilot study and a randomised comparison with timolol. ( Andréasson, S; Jensen, KM, 1983)
"Pindolol, a strong beta-adrenergic blocking agent, instilled into the conjunctival sac of normal and glaucomatous eyes, produced a significant drop in intraocular pressure."5.04Effect of pindolol on intraocular pressure. ( Bonomi, I; Steindler, P, 1975)
"The decrease in intraocular pressure elicited by isoproterenol in ocular normotensive animals is widely recognized."3.67Pharmacological characterization of beta-adrenoceptor subtype involvement in the ocular hypotensive response to beta-adrenergic stimulation. ( Chen, J; Padillo, E; Ruiz, G; Woodward, DF, 1986)
"Pindolol eye drops were compared with Timolol in a randomized 4-week investigation carried out in patients suffering from open-angle glaucoma."2.65[Clinical suitability of pindolol eyedrops in the treatment of chronic open-angle glaucoma]. ( Dausch, D; Görlich, W; Honegger, H, 1984)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199023 (92.00)18.7374
1990's2 (8.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bleckmann, H2
Dorow, P2
Andréasson, S1
Jensen, KM1
Merté, HJ2
Stryz, JR2
Mertz, M1
Dausch, D2
Görlich, W3
Honegger, H2
Mekki, QA1
Penhall, R1
Edgar, DF3
Stewart-Jones, JH3
Turner, P3
Smith, RJ1
Blamires, T1
Nagasubramanian, S1
Watkins, R1
Poinoosawmy, D1
Rowley, S1
Staunton, JE1
Tosch, A1
Tyas, C1
Bonomi, L1
Perfetti, S1
Noya, E1
Bellucci, R1
Massa, F1
Smith, SE1
Smith, SA1
Reynolds, F1
Whitmarsh, VB1
Bonomi, I1
Steindler, P1
Grajewski, AL1
Ferrari-Dileo, G1
Feuer, WJ1
Anderson, DR1
Drance, SM1
Douglas, GR1
Wijsman, KJ1
Schulzer, M1
Himber, J1
Velly, J1
Kintz, P1
de Burlet, G1
Andermann, G1
Leclerc, G1
Diestelhorst, M1
Krieglstein, GK1
Strempel, I1
Woodward, DF1
Chen, J1
Padillo, E1
Ruiz, G1
Schnarr, KD1
Sugrue, MF1
Gautheron, P1
Grove, J1
Mallorga, P1
Viader, MP1
Baldwin, JJ1
Ponticello, GS1
Varga, SL1
Flammer, J1
Robert, Y2
Gloor, B1
Hendrickson, P1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Trabeculectomy, Glaucoma Drainage Device, Cyclophotocoagulation, and Ocular Hypotensive Eye-drops on Intraocular Pressure Fluctuation With Postural Change in Eyes With Open-angle Glaucoma[NCT02868502]150 participants (Anticipated)Observational2016-09-30Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

16 trials available for pindolol and Intraocular Pressure

ArticleYear
[Indications and contraindications of beta blockaders in the treatment of glaucoma].
    Deutsche medizinische Wochenschrift (1946), 1984, Feb-03, Volume: 109, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Airway Resistance; Female; Glaucoma; Humans; Intraocular P

1984
Effect of pindolol on intraocular pressure in glaucoma: pilot study and a randomised comparison with timolol.
    The British journal of ophthalmology, 1983, Volume: 67, Issue:4

    Topics: Clinical Trials as Topic; Double-Blind Method; Glaucoma, Open-Angle; Humans; Intraocular Pressure; O

1983
[Pindolol eye drops (Glauco-Visken) - half year's results in glaucoma therapy].
    Klinische Monatsblatter fur Augenheilkunde, 1984, Volume: 184, Issue:3

    Topics: Adult; Aged; Blood Pressure; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Female; Glauco

1984
[Is pindolol suitable for the therapy of glaucoma? Evaluation of the dose-effect of various concentrations of pindolol eyedrops].
    Klinische Monatsblatter fur Augenheilkunde, 1984, Volume: 184, Issue:6

    Topics: Adult; Aged; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Female

1984
[Clinical suitability of pindolol eyedrops in the treatment of chronic open-angle glaucoma].
    Klinische Monatsblatter fur Augenheilkunde, 1984, Volume: 184, Issue:6

    Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; In

1984
Local and systemic effects of pindolol eye drops.
    British journal of clinical pharmacology, 1983, Volume: 15, Issue:1

    Topics: Adult; Double-Blind Method; Female; Heart Rate; Humans; Intraocular Pressure; Male; Ophthalmic Solut

1983
Addition of pindolol to routine medical therapy: a clinical trial.
    The British journal of ophthalmology, 1982, Volume: 66, Issue:2

    Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma, Open-A

1982
A noninvasive tonometer in the measurement of the effects of pindolol and timolol on intraocular pressure in normal subjects.
    The British journal of ophthalmology, 1981, Volume: 65, Issue:8

    Topics: Adolescent; Adult; Female; Humans; Intraocular Pressure; Male; Pindolol; Propanolamines; Pulse; Timo

1981
The effect of 0.25% and 0.5% pindolol in intraocular pressure in normal human volunteers.
    Current medical research and opinion, 1981, Volume: 7, Issue:8

    Topics: Adolescent; Adult; Female; Heart Rate; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Osm

1981
Ocular and cardiovascular effects of local and systemic pindolol.
    The British journal of ophthalmology, 1979, Volume: 63, Issue:1

    Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Female; Heart Rate; Humans; I

1979
Effect of pindolol on intraocular pressure.
    The British journal of ophthalmology, 1975, Volume: 59, Issue:6

    Topics: Adult; Aged; Aqueous Humor; Clinical Trials as Topic; Female; Glaucoma; Humans; Intraocular Pressure

1975
Adrenergic and adrenolytic effects on intraocular pressure.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1991, Volume: 229, Issue:1

    Topics: Administration, Topical; Analysis of Variance; Drug Therapy, Combination; Epinephrine; Humans; Intra

1991
The effect of betablockers with and without ISA on tonographic outflow facility.
    International ophthalmology, 1989, Volume: 13, Issue:1-2

    Topics: Aqueous Humor; Clinical Trials as Topic; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular

1989
[Immediate effect of a topical beta-blocker on breakup time].
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1986, Volume: 192, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Female; Humans; Intraocular Pressure; Levobunolol; Male; Metipra

1986
[Effect of various beta blockers on intraocular pressure and ventilation].
    Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1986, Volume: 83, Issue:5

    Topics: Airway Resistance; Clinical Trials as Topic; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Lun

1986
Influence of pindolol and timolol treatment on the visual fields of glaucoma patients.
    Journal of ocular pharmacology, 1986,Fall, Volume: 2, Issue:4

    Topics: Blood Pressure; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Pindolol; Prospect

1986

Other Studies

9 other studies available for pindolol and Intraocular Pressure

ArticleYear
Comparison of the effects of nine beta-adrenergic blocking agents on intraocular pressure in rabbits.
    Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1979, Mar-05, Volume: 210, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Drug Tolerance; Ethanolamines; Intraocular Pressure;

1979
Beta-adrenergic responsiveness of choroidal vasculature.
    Ophthalmology, 1991, Volume: 98, Issue:6

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Animals; Autoradiography; Choroid; Fema

1991
Beta-adrenoceptor binding potencies of new aliphatic and alicyclic oxime ethers and their relevance to intraocular pressure control.
    Methods and findings in experimental and clinical pharmacology, 1989, Volume: 11, Issue:5

    Topics: Animals; Cilia; Female; Heart; In Vitro Techniques; Intraocular Pressure; Iodine Radioisotopes; Iodo

1989
Pharmacological characterization of beta-adrenoceptor subtype involvement in the ocular hypotensive response to beta-adrenergic stimulation.
    Experimental eye research, 1986, Volume: 43, Issue:1

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Dose-Response Relationship, Drug; Fe

1986
[Comparative multicenter study of carteolol eyedrops with other beta blockers in 768 patients under normal conditions].
    Klinische Monatsblatter fur Augenheilkunde, 1988, Volume: 192, Issue:2

    Topics: Adrenergic beta-Antagonists; Carteolol; Drug Evaluation; Glaucoma; Humans; Intraocular Pressure; Met

1988
L-653,328: an ocular hypotensive agent with modest beta receptor blocking activity.
    Investigative ophthalmology & visual science, 1988, Volume: 29, Issue:5

    Topics: Adrenergic beta-Antagonists; Animals; Betaxolol; Ciliary Body; Dose-Response Relationship, Drug; Int

1988
[Results of 1-year use of local pindolol in open-angle glaucoma].
    Klinische Monatsblatter fur Augenheilkunde, 1985, Volume: 186, Issue:1

    Topics: Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ophthalmic Solutions; Pindolol; Timolol

1985
[Is the use of beta receptor blockers in variously strong concentrations in the treatment of glaucoma sensible?].
    Klinische Monatsblatter fur Augenheilkunde, 1985, Volume: 186, Issue:2

    Topics: Dose-Response Relationship, Drug; Glaucoma; Humans; Intraocular Pressure; Pindolol; Risk; Timolol

1985
[Evaluation of the effectiveness of beta blockers on the eye].
    Klinische Monatsblatter fur Augenheilkunde, 1985, Volume: 186, Issue:6

    Topics: Adult; Blood Pressure; Humans; Intraocular Pressure; Optic Disk; Pindolol; Timolol

1985