pindolol has been researched along with Intermittent Claudication in 6 studies
Pindolol: A moderately lipophilic beta blocker (ADRENERGIC BETA-ANTAGONISTS). It is non-cardioselective and has intrinsic sympathomimetic actions, but little membrane-stabilizing activity. (From Martindale, The Extra Pharmocopoeia, 30th ed, p638)
pindolol : A member of the class of indols which is the 2-hydroxy-3-(isopropylamino)propyl ether derivative of 1H-indol-4-ol.
Intermittent Claudication: A symptom complex characterized by pain and weakness in SKELETAL MUSCLE group associated with exercise, such as leg pain and weakness brought on by walking. Such muscle limpness disappears after a brief rest and is often relates to arterial STENOSIS; muscle ISCHEMIA; and accumulation of LACTATE.
Excerpt | Relevance | Reference |
---|---|---|
"In a six month placebo-controlled cross-over trial twenty patients with hypertension and peripheral arterial disease were randomised to captopril 25 mg twice daily, atenolol 100 mg once daily, labetalol 200 mg twice daily, or pindolol 10 mg twice daily for one month." | 9.06 | Placebo-controlled comparison of captopril, atenolol, labetalol, and pindolol in hypertension complicated by intermittent claudication. ( Breckenridge, A; McLoughlin, GA; Roberts, DH; Tsao, Y, 1987) |
" Heart rate was lowest during propranolol dosing and blood pressure was lowest during labetalol dosing irrespective of the labetalol dose used." | 6.66 | Chronic effects of labetalol, pindolol, and propranolol on calf blood flow in intermittent claudication. ( Lepäntalo, M, 1985) |
"In a six month placebo-controlled cross-over trial twenty patients with hypertension and peripheral arterial disease were randomised to captopril 25 mg twice daily, atenolol 100 mg once daily, labetalol 200 mg twice daily, or pindolol 10 mg twice daily for one month." | 5.06 | Placebo-controlled comparison of captopril, atenolol, labetalol, and pindolol in hypertension complicated by intermittent claudication. ( Breckenridge, A; McLoughlin, GA; Roberts, DH; Tsao, Y, 1987) |
" Seven patients with intermittent claudication were randomly allocated to treatment with atenolol 100 mg or pindolol 10 mg." | 5.06 | The effect of beta-blockade on leg blood flow in hypertensive patients with intermittent claudication. ( Boström, PA; Janzon, L; Ohlsson, O; Westergren, A, 1986) |
"For this update, the Cochrane Peripheral Vascular Diseases Group Trials Search Co-ordinator searched the Specialised Register (last searched March 2013) and the Cochrane Central Register of Controlled Trials (CENTRAL, The Cochrane Library, 2013, Issue 2)." | 2.49 | Beta blockers for peripheral arterial disease. ( Da Silva, A; Mendonca, DA; Paravastu, SC, 2013) |
"The Cochrane Peripheral Vascular Diseases (PVD) Group searched for publications describing randomised controlled trials (RCTs) of beta blockers in PAD in their Trials Register (last searched 6 May 2008) and the Cochrane Central Register of Controlled Trials (CENTRAL) (last searched The Cochrane Library 2008, Issue 2)." | 2.44 | Beta blockers for peripheral arterial disease. ( Da Silva, A; Mendonca, D; Paravastu, SC, 2008) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 4 (66.67) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (16.67) | 29.6817 |
2010's | 1 (16.67) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Paravastu, SC | 2 |
Mendonca, DA | 1 |
Da Silva, A | 2 |
Mendonca, D | 1 |
Lepäntalo, M | 2 |
Roberts, DH | 1 |
Tsao, Y | 1 |
McLoughlin, GA | 1 |
Breckenridge, A | 1 |
Boström, PA | 1 |
Janzon, L | 1 |
Ohlsson, O | 1 |
Westergren, A | 1 |
2 reviews available for pindolol and Intermittent Claudication
Article | Year |
---|---|
Beta blockers for peripheral arterial disease.
Topics: Adrenergic beta-Antagonists; Atenolol; Humans; Intermittent Claudication; Metoprolol; Peripheral Vas | 2013 |
Beta blockers for peripheral arterial disease.
Topics: Adrenergic beta-Antagonists; Atenolol; Humans; Intermittent Claudication; Metoprolol; Peripheral Vas | 2008 |
4 trials available for pindolol and Intermittent Claudication
Article | Year |
---|---|
Beta blockade and intermittent claudication.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Clinical Trials as Topic; Coronary Disease; Female; Gait; | 1985 |
Placebo-controlled comparison of captopril, atenolol, labetalol, and pindolol in hypertension complicated by intermittent claudication.
Topics: Atenolol; Blood Pressure; Captopril; Clinical Trials as Topic; Double-Blind Method; Exercise Test; F | 1987 |
The effect of beta-blockade on leg blood flow in hypertensive patients with intermittent claudication.
Topics: Adult; Aged; Atenolol; Blood Flow Velocity; Blood Pressure; Gait; Humans; Hypertension; Intermittent | 1986 |
Chronic effects of labetalol, pindolol, and propranolol on calf blood flow in intermittent claudication.
Topics: Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Ethanolamines; Heart Rate; Huma | 1985 |