pindolol has been researched along with Hypothermia in 6 studies
Pindolol: A moderately lipophilic beta blocker (ADRENERGIC BETA-ANTAGONISTS). It is non-cardioselective and has intrinsic sympathomimetic actions, but little membrane-stabilizing activity. (From Martindale, The Extra Pharmocopoeia, 30th ed, p638)
pindolol : A member of the class of indols which is the 2-hydroxy-3-(isopropylamino)propyl ether derivative of 1H-indol-4-ol.
Hypothermia: Lower than normal body temperature, especially in warm-blooded animals.
| Excerpt | Relevance | Reference |
|---|---|---|
| ") significantly attenuated MSO-induced hypothermia, but pretreatment with ketanserin (0." | 7.68 | Hypothermia induced by infusion of methionine sulfoximine into the dorsal raphe nucleus of the rat: involvement of 5-HT1A and GABAB receptors. ( Gayet, J; Ginefri-Gayet, M, 1993) |
| "The hypothermia was brought about by a decrease in metabolic rate at Ta 8 degrees C, whereas at Ta 22 degrees C the hypothermia was produced by both a decrease in metabolic rate and an increase in cutaneous temperature." | 5.31 | Melatonin potentiates 5-HT(1A) receptor activation in rat hypothalamus and results in hypothermia. ( Chuang, JI; Lin, MT, 2002) |
| ") antagonized the hypothermia induced by the D2/D1 receptor agonist, apomorphine (16 mg/kg, s." | 3.70 | Psychopharmacological profile of the selective serotonin reuptake inhibitor, paroxetine: implication of noradrenergic and serotonergic mechanisms. ( Baker, GB; Bourin, M; Colombel, MC; Redrobe, JP, 1998) |
| ") significantly attenuated MSO-induced hypothermia, but pretreatment with ketanserin (0." | 3.68 | Hypothermia induced by infusion of methionine sulfoximine into the dorsal raphe nucleus of the rat: involvement of 5-HT1A and GABAB receptors. ( Gayet, J; Ginefri-Gayet, M, 1993) |
| "5]- decane-7,9-dione (BMY 7378) (5 mg/kg) did not significantly depress body temperature, but pretreatment with BMY 7378 blocked hypothermia induced by the selective 5-HT1A agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT)." | 3.68 | Serotonin 5-HT1A receptor-mediated hypothermia in mice: absence of spare receptors and rapid induction of tolerance. ( Bohmaker, K; Chalfin, M; Meller, E, 1992) |
| "The hypothermia was brought about by a decrease in metabolic rate at Ta 8 degrees C, whereas at Ta 22 degrees C the hypothermia was produced by both a decrease in metabolic rate and an increase in cutaneous temperature." | 1.31 | Melatonin potentiates 5-HT(1A) receptor activation in rat hypothalamus and results in hypothermia. ( Chuang, JI; Lin, MT, 2002) |
| "The acetone extract was functioned into 4 fractions by column chromatography." | 1.28 | [The effect of ginger on serotonin induced hypothermia and diarrhea]. ( Huang, Q; Matsuda, H; Sakai, K; Tamai, Y; Yamahara, J, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (83.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, MT | 1 |
| Chuang, JI | 1 |
| Ginefri-Gayet, M | 1 |
| Gayet, J | 1 |
| Cryan, JF | 1 |
| McGrath, C | 1 |
| Leonard, BE | 1 |
| Norman, TR | 1 |
| Redrobe, JP | 1 |
| Bourin, M | 1 |
| Colombel, MC | 1 |
| Baker, GB | 1 |
| Meller, E | 1 |
| Chalfin, M | 1 |
| Bohmaker, K | 1 |
| Huang, Q | 1 |
| Matsuda, H | 1 |
| Sakai, K | 1 |
| Yamahara, J | 1 |
| Tamai, Y | 1 |
6 other studies available for pindolol and Hypothermia
| Article | Year |
|---|---|
Melatonin potentiates 5-HT(1A) receptor activation in rat hypothalamus and results in hypothermia.
Topics: 5,7-Dihydroxytryptamine; Amphetamines; Animals; Body Temperature Regulation; Dopamine; Hypothalamus; | 2002 |
Hypothermia induced by infusion of methionine sulfoximine into the dorsal raphe nucleus of the rat: involvement of 5-HT1A and GABAB receptors.
Topics: 4-Aminobutyrate Transaminase; Aminocaproates; Animals; Baclofen; Bicuculline; Body Temperature Regul | 1993 |
Combining pindolol and paroxetine in an animal model of chronic antidepressant action--can early onset of action be detected?
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Animals; Antidepressive Agents; | 1998 |
Psychopharmacological profile of the selective serotonin reuptake inhibitor, paroxetine: implication of noradrenergic and serotonergic mechanisms.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amines; Animals; Antidepressive Agents; Apomorphine; Brain; | 1998 |
Serotonin 5-HT1A receptor-mediated hypothermia in mice: absence of spare receptors and rapid induction of tolerance.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Body Temperature; Col | 1992 |
[The effect of ginger on serotonin induced hypothermia and diarrhea].
Topics: Acetone; Animals; Catechols; Diarrhea; Fatty Alcohols; Hypothermia; Ketanserin; Mice; Pindolol; Plan | 1990 |