pindolol has been researched along with Hyperthyroidism in 23 studies
Pindolol: A moderately lipophilic beta blocker (ADRENERGIC BETA-ANTAGONISTS). It is non-cardioselective and has intrinsic sympathomimetic actions, but little membrane-stabilizing activity. (From Martindale, The Extra Pharmocopoeia, 30th ed, p638)
pindolol : A member of the class of indols which is the 2-hydroxy-3-(isopropylamino)propyl ether derivative of 1H-indol-4-ol.
Hyperthyroidism: Hypersecretion of THYROID HORMONES from the THYROID GLAND. Elevated levels of thyroid hormones increase BASAL METABOLIC RATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The authors report four new cases of hyperthyroidism associated with prolonged treatment with amiodarone." | 7.65 | [Hyperthyroidism caused by amiodarone. Apropos of 4 clinical cases]. ( Chapelle, M; Naouri, R; Wolff, F, 1976) |
| "Cardioselective [Acebutolol (N = 10)] or noncardioselective [Oxprenolol (N = 9)] or [Pindolol (N = 9)] beta-adrenergic blockers were given to patients with suspected hyperthyroidism." | 3.67 | Short-term beta-adrenergic blockade decreases serum thyroglobulin in hyper- and euthyroid patients. ( Feldt-Rasmussen, U; Kayser, L; Mølholm Hansen, J; Perrild, H, 1986) |
| " There was a decrease in sensitivity to isoproterenol in spontaneously beating right atria, electrically driven left atria and field-stimulated vas deferens associated with hypothyroidism, with no change in maximum response." | 3.67 | Thyroid status and adrenergic receptor subtypes in the rat: comparison of receptor density and responsiveness. ( Abel, PW; Fox, AW; Johnson, RD; Juberg, EN; May, JM; Minneman, KP, 1985) |
| "In isolated sc adipocytes removed from hyperthyroid patients, the specific binding of [3H]dihydroalprenolol and [125I]iodocyanopindolol was greater than that in adipocytes from normal subjects." | 3.67 | Adrenergic regulation of lipolysis in human adipocytes: findings in hyper- and hypothyroidism. ( Arner, P; Engfeldt, P; Ostman, J; Wahrenberg, H; Wennlund, A, 1986) |
| "The ability of 10 muM epinephrine or isoproterenol to stimulate cyclic AMP accumulation was decreased in hepatocytes isolated from hyperthyroid (triiodothyronine treated) as compared to euthyroid rats." | 3.66 | 3,3',5-triiodothyronine administration in vivo modulates the hormone-sensitive adenylate cyclase system of rat hepatocytes. ( Greenberg, ML; Malbon, CC, 1982) |
| "The authors report four new cases of hyperthyroidism associated with prolonged treatment with amiodarone." | 3.65 | [Hyperthyroidism caused by amiodarone. Apropos of 4 clinical cases]. ( Chapelle, M; Naouri, R; Wolff, F, 1976) |
| "Propranolol is a beta-blocker devoid of intrinsic sympathetic activity whereas pindolol possesses such activity." | 1.27 | [Pathogenesis of tachycardia in hyperthyroidism. Value of Holter monitoring and the use of a beta-blocker]. ( Abadie, E; Babalis, D; Blanche, PM; Coumel, P; Fisch, A; Leclercq, JF; Passa, P, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Váradi, A | 1 |
| Földes, J | 1 |
| Gyertyánffy, G | 1 |
| Borvendég, J | 1 |
| Brüll, J | 1 |
| Malbon, CC | 1 |
| Greenberg, ML | 1 |
| Endo, Y | 1 |
| Abadie, E | 2 |
| Leclercq, JF | 2 |
| Passa, P | 2 |
| Bilezikian, JP | 1 |
| Loeb, JN | 1 |
| Gammon, DE | 1 |
| Schoenen, J | 1 |
| Delwaide, PJ | 1 |
| Wanibe, H | 1 |
| Nihei, R | 1 |
| Okada, T | 1 |
| Chapelle, M | 1 |
| Naouri, R | 1 |
| Wolff, F | 1 |
| Sankalé, M | 1 |
| Ruscher, H | 1 |
| Frament, V | 1 |
| Pierredon, MS | 1 |
| Elks, ML | 1 |
| Manganiello, VC | 1 |
| Hawthorn, MH | 1 |
| Gengo, P | 1 |
| Wei, XY | 1 |
| Rutledge, A | 1 |
| Moran, JF | 1 |
| Gallant, S | 1 |
| Triggle, DJ | 1 |
| Perrild, H | 1 |
| Feldt-Rasmussen, U | 1 |
| Kayser, L | 1 |
| Mølholm Hansen, J | 1 |
| Fox, AW | 1 |
| Juberg, EN | 1 |
| May, JM | 1 |
| Johnson, RD | 1 |
| Abel, PW | 1 |
| Minneman, KP | 1 |
| Fisch, A | 1 |
| Babalis, D | 1 |
| Blanche, PM | 1 |
| Coumel, P | 1 |
| Wahrenberg, H | 1 |
| Engfeldt, P | 1 |
| Arner, P | 1 |
| Wennlund, A | 1 |
| Ostman, J | 1 |
| Makiuchi, M | 1 |
| Turner, P | 1 |
| Färber, A | 1 |
| Offerhaus, L | 1 |
| Damany, SJ | 1 |
| Bhatt, GR | 1 |
| Tikare, SK | 1 |
| Thaly, KG | 1 |
| Gupta, PS | 1 |
| Holmes, D | 1 |
| Schutz, W | 1 |
| Jaffiol, C | 1 |
| Djabri, M | 1 |
| Baldet, L | 1 |
| Mirouze, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Thyroid Hormone-Induced Lipolysis: An In Vivo Microdialysis Study[NCT00312715] | 41 participants (Actual) | Observational | 2006-04-03 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for pindolol and Hyperthyroidism
| Article | Year |
|---|---|
Beta-adrenergic receptor blocking drugs in hyperthyroidism.
Topics: Adrenergic beta-Antagonists; Alprenolol; Antithyroid Agents; Ethanolamines; Humans; Hyperthyroidism; | 1974 |
[Clinical application of beta-blockaders].
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Anxiety Diso | 1973 |
4 trials available for pindolol and Hyperthyroidism
| Article | Year |
|---|---|
[Acute effects of beta receptor blockaders in hyperthyroidism].
Topics: Adrenergic beta-Antagonists; Adult; Clinical Trials as Topic; Drug Evaluation; Female; Heart; Humans | 1981 |
[Indications for beta-blockers in neurology].
Topics: Alcoholism; Antiparkinson Agents; Anxiety; Clinical Trials as Topic; Drug Therapy, Combination; Huma | 1978 |
Visken (LB-46) a double blind cross-over study in cardiac arrhythmias.
Topics: Arrhythmias, Cardiac; Clinical Trials as Topic; Humans; Hyperthyroidism; Pindolol; Placebos; Propran | 1972 |
A new beta-adrenergic blocking agent in cardiac arrhythmias.
Topics: Adult; Aged; Arrhythmias, Cardiac; Female; Humans; Hyperthyroidism; Male; Middle Aged; Pindolol; Pla | 1972 |
17 other studies available for pindolol and Hyperthyroidism
| Article | Year |
|---|---|
3,3',5-triiodothyronine administration in vivo modulates the hormone-sensitive adenylate cyclase system of rat hepatocytes.
Topics: Adenylyl Cyclases; Animals; Benzyl Alcohols; Cholera Toxin; Cyclic AMP; Epinephrine; Female; Glucago | 1982 |
Thyrotoxicosis.
Topics: Adult; Creatine Kinase; Female; Humans; Hyperthyroidism; Muscular Diseases; Pain; Pindolol | 1984 |
Pindolol and hyperthyroidism.
Topics: Heart Rate; Humans; Hyperthyroidism; Pindolol | 1983 |
The influence of hyperthyroidism and hypothyroidism on the beta-adrenergic responsiveness of the turkey erythrocyte.
Topics: Adenylyl Cyclases; Animals; Catecholamines; Cyclic AMP; Erythrocytes; Hyperthyroidism; Hypothyroidis | 1979 |
[Effects of pindolol on hyperthyroidism].
Topics: Adult; Female; Humans; Hyperthyroidism; Male; Middle Aged; Pindolol | 1978 |
[Hyperthyroidism caused by amiodarone. Apropos of 4 clinical cases].
Topics: Adult; Amiodarone; Angina Pectoris; Arrhythmias, Cardiac; Benzofurans; Electrocardiography; Female; | 1976 |
[The utilization of pindolol in the African Black. Apropos of 24 patients with hyperthyroidism or arterial hypertension].
Topics: Adult; Africa; Black People; Drug Evaluation; Female; Humans; Hypertension; Hyperthyroidism; Male; M | 1975 |
Effects of thyroid hormone on regulation of lipolysis and adenosine 3',5'-monophosphate metabolism in 3T3-L1 adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Adipose Tissue; | 1985 |
Effect of thyroid status on beta-adrenoceptors and calcium channels in rat cardiac and vascular tissue.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1988 |
Short-term beta-adrenergic blockade decreases serum thyroglobulin in hyper- and euthyroid patients.
Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Aged; Female; Humans; Hyperthyroidism; Male; Middle | 1986 |
Thyroid status and adrenergic receptor subtypes in the rat: comparison of receptor density and responsiveness.
Topics: Animals; Cerebral Cortex; Ethanolamines; Heart; Heart Rate; Hyperthyroidism; Hypothyroidism; In Vitr | 1985 |
[Pathogenesis of tachycardia in hyperthyroidism. Value of Holter monitoring and the use of a beta-blocker].
Topics: Adolescent; Adult; Aged; Electrocardiography; Female; Heart Rate; Humans; Hyperthyroidism; Male; Mid | 1985 |
Adrenergic regulation of lipolysis in human adipocytes: findings in hyper- and hypothyroidism.
Topics: Adipose Tissue; Adult; Catecholamines; Dihydroalprenolol; Female; Humans; Hyperthyroidism; Hypothyro | 1986 |
[Therapeutic effects of LB-46 (Carvisken) on tachycardia in hyperthyroidism].
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Antithyroid Agents; Female; Humans; Hyperthyro | 1973 |
[Treatment of tachycardias and arrhythmias. Studies using Visken].
Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Cardiac Complexes, Premature; Coronary Di | 1974 |
Further indications for Visken.
Topics: Female; Heart Rate; Humans; Hypertension; Hyperthyroidism; Male; Neurocirculatory Asthenia; Pindolol | 1972 |
[Value of a beta-blocking drug in prolonged treatment of hyperthyroidism and in the triiodothyronine inhibition assay].
Topics: Adolescent; Adult; Aged; Female; Graves Disease; Humans; Hyperthyroidism; Male; Middle Aged; Pindolo | 1973 |