Page last updated: 2024-11-02

pindolol and Depression, Endogenous

pindolol has been researched along with Depression, Endogenous in 74 studies

Pindolol: A moderately lipophilic beta blocker (ADRENERGIC BETA-ANTAGONISTS). It is non-cardioselective and has intrinsic sympathomimetic actions, but little membrane-stabilizing activity. (From Martindale, The Extra Pharmocopoeia, 30th ed, p638)
pindolol : A member of the class of indols which is the 2-hydroxy-3-(isopropylamino)propyl ether derivative of 1H-indol-4-ol.

Research Excerpts

ExcerptRelevanceReference
" Following on from the suggestion that nefazodone, a specific serotonin reuptake inhibitor and antagonist of 5-HT2, improves 5-HT1A-mediated transmission, we used a pindolol and nefazodone combination treatment for major depressive disorder."7.69Fast onset: an open study of the treatment of major depressive disorder with nefazodone and pindolol combination therapy. ( Bakish, D; Hooper, CL; Miller, CA; Thibaudeau, CA; Thornton, MD; Wiens, A, 1997)
"We describe the successful treatment of five patients with treatment-resistant major depressive disorder (TR-MDD) with a combination pharmacotherapy of pindolol, tryptophan and nefazodone."5.09The 'dalhousie serotonin cocktail' for treatment-resistant major depressive disorder. ( Devarajan, S; Dursun, SM; Kutcher, S, 2001)
"The binding of [125I]p-iodoclonidine to alpha-2, and/or [125I]iodopindolol to beta-1 and beta-2 adrenoceptors was measured in right prefrontal cortex (Brodmann's area 10) and right hippocampus from subjects with DSM-III-R diagnoses of major depression (n = 15) or schizophrenia (n = 8) as well as from control subjects (n = 20)."3.70Brain noradrenergic receptors in major depression and schizophrenia. ( Dilley, G; Klimek, V; Luker, SN; Meltzer, HY; Ordway, GA; Overholser, JC; Rajkowska, G; Stockmeier, CA, 1999)
" Following on from the suggestion that nefazodone, a specific serotonin reuptake inhibitor and antagonist of 5-HT2, improves 5-HT1A-mediated transmission, we used a pindolol and nefazodone combination treatment for major depressive disorder."3.69Fast onset: an open study of the treatment of major depressive disorder with nefazodone and pindolol combination therapy. ( Bakish, D; Hooper, CL; Miller, CA; Thibaudeau, CA; Thornton, MD; Wiens, A, 1997)
"Pindolol has been widely investigated as an augmenter of antidepressant drug response."2.77A short-term double-blind randomized controlled pilot trial with active or placebo pindolol in patients treated with venlafaxine for major depression. ( Bech, P; Lunde, M; Martiny, K; Plenge, P, 2012)
"5 mg/day or placebo for nine days in combination with three consecutive TSD cycles."2.69Sustained antidepressant effect of sleep deprivation combined with pindolol in bipolar depression. A placebo-controlled trial. ( Barbini, B; Benedetti, F; Campori, E; Colombo, C; Smeraldi, E, 1999)
"Pindolol has been reported to hasten the antidepressant action of selective serotonin reuptake inhibitors in open-label and placebo-controlled trials."2.69A double-blind, randomized, placebo-controlled trial of pindolol augmentation in depressive patients resistant to serotonin reuptake inhibitors. Grup de Recerca en Trastorns Afectius. ( Alvarez, E; Artigas, F; Pérez, V; Puigdemont, D; Soler, J, 1999)
"Pindolol treatment was associated with statistically significant reduction in blood pressure and pulse as compared to the control group."2.69The use of pindolol with fluoxetine in the treatment of major depression: final results from a double-blind, placebo-controlled trial. ( Anand, A; Berman, RM; Cappiello, A; Charney, DS; Hu, XS; Miller, HL; Oren, DA, 1999)
" The aim of the present study was to examine whether pindolol may increase the efficacy of a subtherapeutical dosage of trazodone in the treatment of major depression and TRD, defined according to the Thase and Rush criteria (1995)."2.68Efficacy of treatment with trazodone in combination with pindolol or fluoxetine in major depression. ( Desnyder, R; Maes, M; Vandoolaeghe, E, 1996)
"Pindolol was well tolerated by all patients."2.68Pindolol augmentation of treatment-resistant depressed patients. ( Bachar, K; Delgado, PL; Gelenberg, AJ; Moreno, FA, 1997)
"Pindolol tended to attenuate seizure duration, especially at the 10 mg dose."2.67Prolactin and thyrotropin responses to ECT after pindolol administration. A placebo controlled study. ( Lykouras, L; Markianos, M; Papadimitriou, G; Papakostas, Y; Stefanis, C; Stefanis, N, 1993)
"Despite the prevalence and morbidity of bipolar depression, few randomized treatment trials have been conducted to assess clinical efficacy."2.42Acceleration and augmentation strategies for treating bipolar depression. ( Altshuler, LL; Frye, MA; Gitlin, MJ, 2003)

Research

Studies (74)

TimeframeStudies, this research(%)All Research%
pre-19904 (5.41)18.7374
1990's47 (63.51)18.2507
2000's20 (27.03)29.6817
2010's3 (4.05)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Whale, R1
Terao, T2
Cowen, P1
Freemantle, N1
Geddes, J1
de Diego-Adeliño, J1
Portella, MJ1
Puigdemont, D2
Pérez-Egea, R1
Alvarez, E4
Pérez, V3
Martiny, K1
Lunde, M1
Bech, P1
Plenge, P1
Altshuler, LL1
Frye, MA1
Gitlin, MJ1
Isaac, MB2
Isaac, MT8
Gallo, F1
Tournoux, A1
Ballesteros, J1
Callado, LF1
Rabiner, EA1
Bhagwagar, Z1
Gunn, RN1
Cowen, PJ1
Grasby, PM1
Lemonde, S1
Du, L1
Bakish, D2
Hrdina, P1
Albert, PR1
Booij, L1
Van der Does, AJ1
Haffmans, PM1
Riedel, WJ1
Carvalho, AF1
Cavalcante, JL1
Castelo, MS1
Lima, MC1
Artigas, F6
Blier, P5
Bergeron, R3
Howland, RH2
Little, KY2
Clark, TB2
Ranc, J2
Duncan, GE1
Papakostas, Y1
Markianos, M1
Papadimitriou, G1
Stefanis, N1
Lykouras, L1
Stefanis, C1
Anderson, GM1
Romero, L1
de Montigny, C2
Maes, M4
Van de Vyvere, J1
Vandoolaeghe, E3
Bril, T1
Demedts, P2
Wauters, A2
Neels, H2
Werstiuk, ES1
Coote, M1
Griffith, L1
Shannon, H1
Steiner, M1
Desnyder, R1
Berman, RM2
Darnell, AM1
Miller, HL2
Anand, A2
Charney, DS3
Van Hunsel, F2
Gilmore, J1
Patel, A1
Kraus, RP2
Tome, MB6
Harte, R1
Holland, C1
Hooper, CL1
Thornton, MD1
Wiens, A1
Miller, CA1
Thibaudeau, CA1
Cloninger, CR1
Watson, JP1
Bordet, R2
Thomas, P2
Dupuis, B2
Moreno, FA1
Gelenberg, AJ1
Bachar, K1
Delgado, PL1
Zanardi, R4
Franchini, L1
Sforzini, L1
Gasperini, M1
Smeraldi, E5
Perez, J2
Sussman, N2
Joffe, RT2
Thase, ME1
Friedman, ES1
Nelson, JC3
Benedetti, F2
Di Bella, D1
Catalano, M1
McAllister-Williams, RH1
Young, AH1
McAskill, R1
Mir, S1
Taylor, D1
Barbini, B1
Campori, E1
Colombo, C1
Soler, J1
Libbrecht, I1
Campens, D1
Meltzer, HY2
Cappiello, A1
Hu, XS1
Oren, DA1
Klimek, V1
Rajkowska, G1
Luker, SN1
Dilley, G1
Overholser, JC1
Stockmeier, CA1
Ordway, GA1
Goodman, WK1
Fava, M1
Sacristán, JA1
Gilaberte, I1
Boto, B1
Buesching, DP1
Obenchain, RL1
Demitrack, M1
Pérez Sola, V1
Shiah, IS1
Yatham, LN1
Srisurapanont, M1
Lam, RW1
Tam, EM1
Zis, AP2
Tamura, RN1
Faries, DE1
Feng, J1
Coryell, W1
Olver, JS1
Cryan, JF1
Burrows, GD1
Norman, TR1
Dursun, SM1
Devarajan, S1
Kutcher, S1
Serretti, A2
Rossini, D2
Cusin, C2
Lilli, R2
Chaouloff, F1
Lattuada, E1
Lorenzi, C1
Goumeniouk, AD1
Clark, CM1
Remick, RA1
Adams, SA1
Mazzola, P2
Jeanningros, R2
Azorin, JM2
Aligne, L1
Tissot, R2
Samuelian-Massa, C1
Magliozzi, JR1
Gietzen, D1
Maddock, RJ1
Haack, D1
Doran, AR1
Goodman, T1
Weiler, PG1
Pandey, GN1
Janicak, PG1
Davis, JM1
Brown, SL1
Woods, SW1
Heninger, GR1
Tallman, J1
Graafsma, S1
Rodrigues de Miranda, J1
Thien, T1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Short Term Double Blind Randomised Trial of Pindolol Augmentation in Venlafaxine Treated Patients With Major Depression[NCT00159146]31 participants (Actual)Interventional2002-08-31Terminated (stopped due to lack of participants fulfilling inclusion criteria)
Imaging Serotonin 5-HT1A Receptors in the High Affinity State in Brains of Patients With Major Depressive Disorder[NCT01313403]0 participants (Actual)Interventional2011-02-10Withdrawn
Implementation of Dialectical Behavioral Therapy in Juvenile Justice to Reduce Self-Harm and Increase Quality of Life: A Pilot Test[NCT05583279]300 participants (Anticipated)Interventional2023-09-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

15 reviews available for pindolol and Depression, Endogenous

ArticleYear
Pindolol augmentation of serotonin reuptake inhibitors for the treatment of depressive disorder: a systematic review.
    Journal of psychopharmacology (Oxford, England), 2010, Volume: 24, Issue:4

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Antidepressive Agents; Depressive Disorder; Drug Int

2010
Acceleration and augmentation strategies for treating bipolar depression.
    Biological psychiatry, 2003, Apr-15, Volume: 53, Issue:8

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Bipolar

2003
Effectiveness of pindolol plus serotonin uptake inhibitors in depression: a meta-analysis of early and late outcomes from randomised controlled trials.
    Journal of affective disorders, 2004, Volume: 79, Issue:1-3

    Topics: Adolescent; Adult; Aged; Depressive Disorder; Drug Interactions; Drug Therapy, Combination; Female;

2004
Augmentation strategies for treatment-resistant depression: a literature review.
    Journal of clinical pharmacy and therapeutics, 2007, Volume: 32, Issue:5

    Topics: Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Buspirone; Central Ne

2007
Acceleration of the effect of selected antidepressant drugs in major depression by 5-HT1A antagonists.
    Trends in neurosciences, 1996, Volume: 19, Issue:9

    Topics: Antidepressive Agents; Depressive Disorder; Humans; Pindolol; Piperazines; Pyridines; Serotonin Anta

1996
Treating antidepressant nonresponders with augmentation strategies: an overview.
    The Journal of clinical psychiatry, 1998, Volume: 59 Suppl 5

    Topics: Antidepressive Agents; Buspirone; Depressive Disorder; Drug Resistance; Drug Synergism; Drug Therapy

1998
The use of pindolol to potentiate antidepressant medication.
    The Journal of clinical psychiatry, 1998, Volume: 59 Suppl 5

    Topics: Animals; Antidepressive Agents; Autoreceptors; Controlled Clinical Trials as Topic; Depressive Disor

1998
Treatment of antidepressant nonresponders: augmentation or switch?
    The Journal of clinical psychiatry, 1998, Volume: 59 Suppl 15

    Topics: Antidepressive Agents; Bupropion; Clinical Trials as Topic; Depressive Disorder; Drug Administration

1998
Overcoming treatment resistance in depression.
    The Journal of clinical psychiatry, 1998, Volume: 59 Suppl 16

    Topics: Antidepressive Agents; Buspirone; Depressive Disorder; Drug Administration Schedule; Drug Resistance

1998
Pindolol augmentation of antidepressant therapy.
    The British journal of psychiatry : the journal of mental science, 1998, Volume: 173

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents; Controlled Clinical Trials as Topic; Depressive

1998
Obsessive-compulsive disorder: diagnosis and treatment.
    The Journal of clinical psychiatry, 1999, Volume: 60 Suppl 18

    Topics: Anxiety Disorders; Behavior Therapy; Clinical Trials as Topic; Combined Modality Therapy; Comorbidit

1999
New approaches to the treatment of refractory depression.
    The Journal of clinical psychiatry, 2000, Volume: 61 Suppl 1

    Topics: Antidepressive Agents; Buspirone; Depressive Disorder; Drug Therapy, Combination; Humans; Lithium; M

2000
Augmentation strategies in depression 2000.
    The Journal of clinical psychiatry, 2000, Volume: 61 Suppl 2

    Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Buspirone; Depressive

2000
Pindolol augmentation of antidepressants: a review and rationale.
    The Australian and New Zealand journal of psychiatry, 2000, Volume: 34, Issue:1

    Topics: Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder; Drug Synergism; Drug Therapy,

2000
Pharmacology of rapid-onset antidepressant treatment strategies.
    The Journal of clinical psychiatry, 2001, Volume: 62 Suppl 15

    Topics: Antidepressive Agents, Tricyclic; Autoreceptors; Cyclohexanols; Depressive Disorder; Drug Synergism;

2001

Trials

29 trials available for pindolol and Depression, Endogenous

ArticleYear
A short duration of untreated illness (DUI) improves response outcomes in first-depressive episodes.
    Journal of affective disorders, 2010, Volume: 120, Issue:1-3

    Topics: Adult; Citalopram; Depressive Disorder; Diagnostic and Statistical Manual of Mental Disorders; Femal

2010
A short-term double-blind randomized controlled pilot trial with active or placebo pindolol in patients treated with venlafaxine for major depression.
    Nordic journal of psychiatry, 2012, Volume: 66, Issue:3

    Topics: Adult; Aged; Cyclohexanols; Depressive Disorder; Depressive Disorder, Major; Desvenlafaxine Succinat

2012
Effect of pindolol and milnacipran versus milnacipran and placebo on plasma prolactin and adrenocorticotrophic hormone in depressed subjects.
    Human psychopharmacology, 2003, Volume: 18, Issue:7

    Topics: Adrenergic Agents; Adrenocorticotropic Hormone; Adult; Age Factors; Cyclopropanes; Depressive Disord

2003
Milnacipran and pindolol: a randomized trial of reduction of antidepressant latency.
    Human psychopharmacology, 2003, Volume: 18, Issue:8

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Cyclopropanes; Depressive Disorder; Double-Blind Met

2003
Preferential 5-HT1A autoreceptor occupancy by pindolol is attenuated in depressed patients: effect of treatment or an endophenotype of depression?
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2004, Volume: 29, Issue:9

    Topics: Adrenergic beta-Antagonists; Adult; Autoreceptors; Depressive Disorder; Dose-Response Relationship,

2004
Effectiveness of pindolol with selected antidepressant drugs in the treatment of major depression.
    Journal of clinical psychopharmacology, 1995, Volume: 15, Issue:3

    Topics: Adult; Depressive Disorder; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Pindolol;

1995
Prolactin and thyrotropin responses to ECT after pindolol administration. A placebo controlled study.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1993, Volume: 3, Issue:1

    Topics: Adult; Aged; Analysis of Variance; Depressive Disorder; Electroconvulsive Therapy; Female; Humans; M

1993
Alterations in iron metabolism and the erythron in major depression: further evidence for a chronic inflammatory process.
    Journal of affective disorders, 1996, Sep-09, Volume: 40, Issue:1-2

    Topics: Acute-Phase Reaction; Adrenergic beta-Antagonists; Adult; Aged; Antidepressive Agents, Second-Genera

1996
Efficacy of treatment with trazodone in combination with pindolol or fluoxetine in major depression.
    Journal of affective disorders, 1996, Dec-16, Volume: 41, Issue:3

    Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Depressive Disorder; Double-Blind Method; Dru

1996
Effect of pindolol in hastening response to fluoxetine in the treatment of major depression: a double-blind, placebo-controlled trial.
    The American journal of psychiatry, 1997, Volume: 154, Issue:1

    Topics: Adolescent; Adult; Aged; Ambulatory Care; Depressive Disorder; Double-Blind Method; Drug Interaction

1997
Lower total serum protein, albumin, and beta- and gamma-globulin in major and treatment-resistant depression: effects of antidepressant treatments.
    Psychiatry research, 1996, Dec-20, Volume: 65, Issue:3

    Topics: Acute-Phase Proteins; Adrenergic beta-Antagonists; Adult; Aged; Alpha-Globulins; Antidepressive Agen

1996
Paroxetine and pindolol: a randomized trial of serotonergic autoreceptor blockade in the reduction of antidepressant latency.
    International clinical psychopharmacology, 1997, Volume: 12, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Depressive Disorder; Dose-Response Relationship, Drug; Dou

1997
Serotonergic autoreceptor blockade in the reduction of antidepressant latency: personality variables and response to paroxetine and pindolol.
    Journal of affective disorders, 1997, Volume: 44, Issue:2-3

    Topics: Adrenergic beta-Agonists; Adult; Depressive Disorder; Double-Blind Method; Ego; Female; Humans; Male

1997
Selective serotonin reuptake inhibitors plus pindolol.
    Lancet (London, England), 1997, Jul-26, Volume: 350, Issue:9073

    Topics: Adolescent; Adult; Aged; Depressive Disorder; Double-Blind Method; Drug Therapy, Combination; Humans

1997
Pindolol augmentation of treatment-resistant depressed patients.
    The Journal of clinical psychiatry, 1997, Volume: 58, Issue:10

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Ambulatory Care; Depressive Disorder; Double-Blind Method;

1997
How long should pindolol be associated with paroxetine to improve the antidepressant response?
    Journal of clinical psychopharmacology, 1997, Volume: 17, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Antidepressive Agents; Depressive Disorder; Double-Blind Method;

1997
One year real world prospective follow-up study of a major depressive episode of patients treated with paroxetine and pindolol or paroxetine for 6 weeks.
    International clinical psychopharmacology, 1998, Volume: 13, Issue:4

    Topics: Adult; Depressive Disorder; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studie

1998
Cost effectiveness study of a year follow-up of selective serotonin reuptake inhibitor (SSRI) and augmentor combination compared with SSRI and placebo.
    International clinical psychopharmacology, 1998, Volume: 13, Issue:4

    Topics: Cost-Benefit Analysis; Depressive Disorder; Double-Blind Method; Follow-Up Studies; Humans; Paroxeti

1998
Effect of pindolol on onset of action of paroxetine in the treatment of major depression: intermediate analysis of a double-blind, placebo-controlled trial. Réseau de Recherche et d'Expérimentation Psychopharmacologique.
    The American journal of psychiatry, 1998, Volume: 155, Issue:10

    Topics: Adrenergic beta-Antagonists; Adult; Depressive Disorder; Double-Blind Method; Drug Interactions; Dru

1998
Polymorphism within the promoter of the serotonin transporter gene and antidepressant efficacy of fluvoxamine.
    Molecular psychiatry, 1998, Volume: 3, Issue:6

    Topics: Antidepressive Agents, Second-Generation; Carrier Proteins; Depressive Disorder; Drug Therapy, Combi

1998
Sustained antidepressant effect of sleep deprivation combined with pindolol in bipolar depression. A placebo-controlled trial.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1999, Volume: 20, Issue:4

    Topics: Acute Disease; Adrenergic beta-Antagonists; Adult; Affect; Bipolar Disorder; Combined Modality Thera

1999
A double-blind, randomized, placebo-controlled trial of pindolol augmentation in depressive patients resistant to serotonin reuptake inhibitors. Grup de Recerca en Trastorns Afectius.
    Archives of general psychiatry, 1999, Volume: 56, Issue:4

    Topics: Adult; Ambulatory Care; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method;

1999
Pindolol and mianserin augment the antidepressant activity of fluoxetine in hospitalized major depressed patients, including those with treatment resistance.
    Journal of clinical psychopharmacology, 1999, Volume: 19, Issue:2

    Topics: Adult; Aged; Analysis of Variance; Depressive Disorder; Fluoxetine; Humans; Mianserin; Middle Aged;

1999
The use of pindolol with fluoxetine in the treatment of major depression: final results from a double-blind, placebo-controlled trial.
    Biological psychiatry, 1999, May-01, Volume: 45, Issue:9

    Topics: Adult; Depressive Disorder; Double-Blind Method; Female; Fluoxetine; Humans; Male; Middle Aged; Pind

1999
Cost-effectiveness of fluoxetine plus pindolol in patients with major depressive disorder: results from a randomized, double-blind clinical trial.
    International clinical psychopharmacology, 2000, Volume: 15, Issue:2

    Topics: Adult; Antidepressive Agents, Second-Generation; Cost-Benefit Analysis; Depressive Disorder; Double-

2000
Does the addition of pindolol accelerate the response to electroconvulsive therapy in patients with major depression? A double-blind, placebo-controlled pilot study.
    Journal of clinical psychopharmacology, 2000, Volume: 20, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Combined Modality Therapy; Depressive Disorder; Double-Blind Met

2000
The 'dalhousie serotonin cocktail' for treatment-resistant major depressive disorder.
    Journal of psychopharmacology (Oxford, England), 2001, Volume: 15, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Antidepressive Agents; Depressive Disorder; Drug Resistanc

2001
Influence of tryptophan hydroxylase and serotonin transporter genes on fluvoxamine antidepressant activity.
    Molecular psychiatry, 2001, Volume: 6, Issue:5

    Topics: Adult; Age of Onset; Alleles; Antidepressive Agents, Second-Generation; Bipolar Disorder; Carrier Pr

2001
Influence of monoamine oxidase A and serotonin receptor 2A polymorphisms in SSRI antidepressant activity.
    The international journal of neuropsychopharmacology, 2002, Volume: 5, Issue:1

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Second-Generation; Antimanic Agents; Depressive

2002

Other Studies

30 other studies available for pindolol and Depression, Endogenous

ArticleYear
Association of the C(-1019)G 5-HT1A functional promoter polymorphism with antidepressant response.
    The international journal of neuropsychopharmacology, 2004, Volume: 7, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Alleles; Antidepressive Agents; Antidepressive Agents, Second-Ge

2004
Acute tryptophan depletion in depressed patients treated with a selective serotonin-noradrenalin reuptake inhibitor: augmentation of antidepressant response?
    Journal of affective disorders, 2005, Volume: 86, Issue:2-3

    Topics: Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Adult; Depressive Disorder; Female; Human

2005
Pindolol, 5-hydroxytryptamine, and antidepressant augmentation.
    Archives of general psychiatry, 1995, Volume: 52, Issue:11

    Topics: Animals; Antidepressive Agents; Depressive Disorder; Drug Therapy, Combination; Humans; Monoamine Ox

1995
Biochemical effects of antidepressant augmentation.
    Archives of general psychiatry, 1995, Volume: 52, Issue:2

    Topics: Antidepressive Agents; Buspirone; Depressive Disorder; Drug Synergism; Drug Therapy, Combination; Hu

1995
Pindolol induces a rapid improvement of depressed patients treated with serotonin reuptake inhibitors.
    Archives of general psychiatry, 1994, Volume: 51, Issue:3

    Topics: Adult; Aged; Animals; Depressive Disorder; Drug Synergism; Female; Humans; Male; Middle Aged; Monoam

1994
Beta-adrenergic receptor binding in frontal cortex from suicide victims.
    Biological psychiatry, 1993, Nov-01, Volume: 34, Issue:9

    Topics: Adolescent; Adult; Aged; Cause of Death; Depressive Disorder; Female; Frontal Lobe; Humans; Male; Mi

1993
Comments on "Effectiveness of pindolol with selected antidepressant drugs in the treatment of major depression".
    Journal of clinical psychopharmacology, 1996, Volume: 16, Issue:3

    Topics: Adrenergic beta-Antagonists; Depressive Disorder; Drug Synergism; Humans; Pindolol; Selective Seroto

1996
Effects of electroconvulsive therapy on peripheral adrenoceptors, plasma, noradrenaline, MHPG and cortisol in depressed patients.
    The British journal of psychiatry : the journal of mental science, 1996, Volume: 169, Issue:6

    Topics: Adult; Aged; Blood Platelets; Depressive Disorder; Down-Regulation; Electroconvulsive Therapy; Femal

1996
Selective activation of postsynaptic 5-HT1A receptors induces rapid antidepressant response.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1997, Volume: 16, Issue:5

    Topics: Adult; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricy

1997
Lack of pineal beta-adrenergic receptor alterations in suicide victims with major depression.
    Psychoneuroendocrinology, 1997, Volume: 22, Issue:1

    Topics: Adult; Aged; Autoradiography; Depressive Disorder; Female; Humans; Male; Melatonin; Middle Aged; Nor

1997
Rapid cycling triggered by pindolol augmentation of paroxetine, but not with desipramine.
    Depression, 1996, Volume: 4, Issue:2

    Topics: Adult; Antidepressive Agents, Second-Generation; Arousal; Bipolar Disorder; Depressive Disorder; Dos

1996
Pindolol augmentation of tranylcypromine in psychotic depression.
    Journal of clinical psychopharmacology, 1997, Volume: 17, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Antidepressive Agents; Depressive Disorder; Drug Therapy, Combin

1997
Fast onset: an open study of the treatment of major depressive disorder with nefazodone and pindolol combination therapy.
    International clinical psychopharmacology, 1997, Volume: 12, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Antidepressive Agents, Second-Generation; Depressive Disorder; D

1997
Selective serotonin reuptake inhibitors plus pindolol. The REEP.
    Lancet (London, England), 1997, Jul-26, Volume: 350, Issue:9073

    Topics: Depressive Disorder; Fluoxetine; Humans; Paroxetine; Pindolol; Selective Serotonin Reuptake Inhibito

1997
Selective serotonin reuptake inhibitors plus pindolol.
    Lancet (London, England), 1997, Jul-26, Volume: 350, Issue:9073

    Topics: Depressive Disorder; Drug Interactions; Fluoxetine; Humans; Pindolol; Selective Serotonin Reuptake I

1997
Pindolol-paroxetine combination.
    The American journal of psychiatry, 1997, Volume: 154, Issue:12

    Topics: Adult; Age Factors; Animals; Depressive Disorder; Double-Blind Method; Drug Therapy, Combination; Fe

1997
Introduction: augmentation of antidepressant medication.
    The Journal of clinical psychiatry, 1998, Volume: 59 Suppl 5

    Topics: Anticonvulsants; Antidepressive Agents; Buspirone; Calcium Channel Blockers; Depressive Disorder; Dr

1998
Antidepressant augmentation: conclusions and recommendations.
    The Journal of clinical psychiatry, 1998, Volume: 59 Suppl 5

    Topics: Anticonvulsants; Antidepressive Agents; Benzodiazepines; Buspirone; Depressive Disorder; Drug Synerg

1998
Pindolol augmentation of antidepressant therapy.
    The British journal of psychiatry : the journal of mental science, 1998, Volume: 173

    Topics: Antidepressive Agents; Depressive Disorder; Drug Interactions; Drug Therapy, Combination; Humans; Pi

1998
Brain noradrenergic receptors in major depression and schizophrenia.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1999, Volume: 21, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Affinity Labels; Aged; Autoradiograph

1999
Comparing time to onset of response in antidepressant clinical trials using the cure model and the Cramer-von Mises test.
    Statistics in medicine, 2000, Aug-30, Volume: 19, Issue:16

    Topics: Adrenergic beta-Antagonists; Algorithms; Antidepressive Agents; Antidepressive Agents, Second-Genera

2000
Augmentation strategies for inadequate antidepressant response: a review of placebo-controlled studies.
    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 2000, Volume: 12, Issue:3

    Topics: Adjuvants, Immunologic; Dehydroepiandrosterone; Depressive Disorder; Drug Therapy, Combination; Huma

2000
Sympathomimetic effects of pindolol in depression.
    Trends in pharmacological sciences, 2001, Volume: 22, Issue:11

    Topics: Adrenergic beta-Antagonists; Animals; Antidepressive Agents; Depressive Disorder; Drug Synergism; Hu

2001
ECT-induced PRL release: a 5-HT1A-mediated event?
    Biological psychiatry, 1992, Feb-15, Volume: 31, Issue:4

    Topics: Adult; Depressive Disorder; Electroconvulsive Therapy; Female; Humans; Male; Middle Aged; Pindolol;

1992
Early decrease in density of mononuclear leukocyte beta-adrenoceptors in depressed patients following amineptine treatment: possible relation to clinical efficiency.
    Progress in neuro-psychopharmacology & biological psychiatry, 1991, Volume: 15, Issue:3

    Topics: Adult; Aged; Antidepressive Agents; Depressive Disorder; Dibenzocycloheptenes; Female; Humans; Iodin

1991
Beta-adrenoceptor density of intact mononuclear leukocytes in subgroups of depressive disorders.
    Biological psychiatry, 1991, Apr-15, Volume: 29, Issue:8

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Bipolar Disorder; Depressive Disorder; Female; Humans; Mal

1991
Lymphocyte beta-adrenoreceptor density in patients with unipolar depression and normal controls.
    Biological psychiatry, 1989, Volume: 26, Issue:1

    Topics: Adult; Aged; Bipolar Disorder; Depressive Disorder; Female; Humans; Iodocyanopindolol; Lymphocytes;

1989
Decreased beta-adrenergic receptors in the leukocytes of depressed patients.
    Psychiatry research, 1987, Volume: 22, Issue:4

    Topics: Adult; Depressive Disorder; Dexamethasone; Humans; Hydrocortisone; Iodine Radioisotopes; Leukocytes;

1987
Lymphocyte beta-adrenergic receptor binding in panic disorder.
    Psychopharmacology, 1988, Volume: 94, Issue:1

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Agoraphobia; Depressive Disorder; Fear

1988
Reduced sensitivity of lymphocyte beta-adrenergic receptors in patients with endogenous depression and psychomotor agitation.
    The New England journal of medicine, 1986, Apr-03, Volume: 314, Issue:14

    Topics: Depressive Disorder; Humans; In Vitro Techniques; Iodocyanopindolol; Lymphocytes; Pindolol; Psychomo

1986