pindolol has been researched along with Coma in 2 studies
Pindolol: A moderately lipophilic beta blocker (ADRENERGIC BETA-ANTAGONISTS). It is non-cardioselective and has intrinsic sympathomimetic actions, but little membrane-stabilizing activity. (From Martindale, The Extra Pharmocopoeia, 30th ed, p638)
pindolol : A member of the class of indols which is the 2-hydroxy-3-(isopropylamino)propyl ether derivative of 1H-indol-4-ol.
Coma: A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In addition, binding sites for the noradrenergic receptor subtype ligands, [3H]-prazosin (alpha1 sites), [3H]-RX821002 (alpha2 sites), and [125]I-iodopindolol (beta sites), were assessed using quantitative receptor autoradiography in regions of the brains of rats at coma stage of acute liver failure and of control groups of animals." | 3.70 | Evidence for altered central noradrenergic function in experimental acute liver failure in the rat. ( Butterworth, RF; Buu, PN; Michalak, A; Rose, C, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Michalak, A | 1 |
| Rose, C | 1 |
| Buu, PN | 1 |
| Butterworth, RF | 1 |
| Offenstadt, G | 1 |
| Hericord, PH | 1 |
| Amstrutz, PH | 1 |
2 other studies available for pindolol and Coma
| Article | Year |
|---|---|
Evidence for altered central noradrenergic function in experimental acute liver failure in the rat.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Autoradiography; Cerebral Cortex | 1998 |
[Letter: Voluntary poisoning with pindolol].
Topics: Adult; Arrhythmias, Cardiac; Coma; Female; Humans; Hypertension; Pindolol; Substance-Related Disorde | 1976 |