pindolol has been researched along with Central Hypothyroidism in 8 studies
Pindolol: A moderately lipophilic beta blocker (ADRENERGIC BETA-ANTAGONISTS). It is non-cardioselective and has intrinsic sympathomimetic actions, but little membrane-stabilizing activity. (From Martindale, The Extra Pharmocopoeia, 30th ed, p638)
pindolol : A member of the class of indols which is the 2-hydroxy-3-(isopropylamino)propyl ether derivative of 1H-indol-4-ol.
| Excerpt | Relevance | Reference |
|---|---|---|
| " There was a decrease in sensitivity to isoproterenol in spontaneously beating right atria, electrically driven left atria and field-stimulated vas deferens associated with hypothyroidism, with no change in maximum response." | 3.67 | Thyroid status and adrenergic receptor subtypes in the rat: comparison of receptor density and responsiveness. ( Abel, PW; Fox, AW; Johnson, RD; Juberg, EN; May, JM; Minneman, KP, 1985) |
| "In isolated sc adipocytes removed from hyperthyroid patients, the specific binding of [3H]dihydroalprenolol and [125I]iodocyanopindolol was greater than that in adipocytes from normal subjects." | 3.67 | Adrenergic regulation of lipolysis in human adipocytes: findings in hyper- and hypothyroidism. ( Arner, P; Engfeldt, P; Ostman, J; Wahrenberg, H; Wennlund, A, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ghosh, M | 1 |
| Das, S | 1 |
| Rubio, A | 1 |
| Raasmaja, A | 1 |
| Maia, AL | 1 |
| Kim, KR | 1 |
| Silva, JE | 1 |
| Medina-Martínez, O | 1 |
| García-Sáinz, JA | 1 |
| Kragie, L | 1 |
| Kwon, YW | 1 |
| Smiehorowski, R | 1 |
| Bilezikian, JP | 1 |
| Loeb, JN | 1 |
| Gammon, DE | 1 |
| Elks, ML | 1 |
| Manganiello, VC | 1 |
| Fox, AW | 1 |
| Juberg, EN | 1 |
| May, JM | 1 |
| Johnson, RD | 1 |
| Abel, PW | 1 |
| Minneman, KP | 1 |
| Wahrenberg, H | 1 |
| Engfeldt, P | 1 |
| Arner, P | 1 |
| Wennlund, A | 1 |
| Ostman, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Thyroid Hormone-Induced Lipolysis: An In Vivo Microdialysis Study[NCT00312715] | 41 participants (Actual) | Observational | 2006-04-03 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 other studies available for pindolol and Central Hypothyroidism
| Article | Year |
|---|---|
Increased beta(2)-adrenergic receptor activity by thyroid hormone possibly leads to differentiation and maturation of astrocytes in culture.
Topics: Adrenergic beta-2 Receptor Antagonists; Animals; Animals, Newborn; Astrocytes; Cell Differentiation; | 2007 |
Effects of thyroid hormone on norepinephrine signaling in brown adipose tissue. I. Beta 1- and beta 2-adrenergic receptors and cyclic adenosine 3',5'-monophosphate generation.
Topics: Adipose Tissue, Brown; Adrenergic Agents; Adrenergic beta-Antagonists; Animals; Cyclic AMP; Hypothyr | 1995 |
Hepatocyte homologous beta 2-adrenergic desensitization is associated with a decrease in number of plasma membrane beta 2-adrenoceptors.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Alkaline Phosphatase; Animals; Autoradiography; Bin | 1993 |
Rat cardiac calcium channels and their relationships with beta-adrenergic and muscarinic receptors in hypothyroidism.
Topics: Animals; Calcium; Calcium Channels; Carbachol; Dose-Response Relationship, Drug; Heart Rate; Hypothy | 1993 |
The influence of hyperthyroidism and hypothyroidism on the beta-adrenergic responsiveness of the turkey erythrocyte.
Topics: Adenylyl Cyclases; Animals; Catecholamines; Cyclic AMP; Erythrocytes; Hyperthyroidism; Hypothyroidis | 1979 |
Effects of thyroid hormone on regulation of lipolysis and adenosine 3',5'-monophosphate metabolism in 3T3-L1 adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Adipose Tissue; | 1985 |
Thyroid status and adrenergic receptor subtypes in the rat: comparison of receptor density and responsiveness.
Topics: Animals; Cerebral Cortex; Ethanolamines; Heart; Heart Rate; Hyperthyroidism; Hypothyroidism; In Vitr | 1985 |
Adrenergic regulation of lipolysis in human adipocytes: findings in hyper- and hypothyroidism.
Topics: Adipose Tissue; Adult; Catecholamines; Dihydroalprenolol; Female; Humans; Hyperthyroidism; Hypothyro | 1986 |