pindolol has been researched along with Cardiovascular Pregnancy Complications in 17 studies
Pindolol: A moderately lipophilic beta blocker (ADRENERGIC BETA-ANTAGONISTS). It is non-cardioselective and has intrinsic sympathomimetic actions, but little membrane-stabilizing activity. (From Martindale, The Extra Pharmocopoeia, 30th ed, p638)
pindolol : A member of the class of indols which is the 2-hydroxy-3-(isopropylamino)propyl ether derivative of 1H-indol-4-ol.
| Excerpt | Relevance | Reference |
|---|---|---|
| "29 women with pregnancy induced hypertension in the third trimester, 13 randomised to atenolol and 16 to pindolol." | 9.07 | Randomised controlled trial of atenolol and pindolol in human pregnancy: effects on fetal haemodynamics. ( Ingemarsson, I; Marsál, K; Montan, S; Sjöberg, NO, 1992) |
| "Thirty-two consecutive women with pregnancy-induced hypertension of early onset were randomly allocated to treatment with pindolol or methyldopa." | 9.06 | Management of pregnancy-induced hypertension with pindolol--comparative study with methyldopa. ( Anderman, S; Davidson, A; Ellenbogen, A; Grunstein, S; Jaschevatzky, O, 1986) |
| "Forty-four consecutive patients referred for treatment because of hypertension (greater than 150/90 mmHg) occurring during pregnancy were randomly allocated to one of two treatment groups, hydralazine alone (n = 21) or hydralazine combined with pindolol (n = 23)." | 9.06 | Treatment of hypertension during pregnancy with hydralazine monotherapy or with combined therapy with hydralazine and pindolol. ( Boner, G; Bott-Kanner, G; Friedman, S; Merlob, P; Nissenkorn, A; Ovadia, J; Paran, E; Reisner, S; Rosenfeld, J; Zmora, E, 1986) |
| "Nine patients taking oral doses of 10 mg/12 h rac-pindolol as part of their treatment for hypertension in pregnancy were recruited for the study." | 7.71 | Enantioselectivity in the steady-state pharmacokinetics and transplacental distribution of pindolol at delivery in pregnancy-induced hypertension. ( Da Cunha, SP; Gonçalves, PV; Lanchote, VL; Matthes, Ado C, 2002) |
| "Renal hypertension was induced by partial clamping of both renal arteries in female Wistar rats 4 weeks before pregnancy." | 5.27 | Acute haemodynamic effects of pindolol during pregnancy in experimental renal hypertension. ( Karlsson, K; Ljungblad, U; Lundgren, Y, 1984) |
| "Fifty-one women with pregnancy-induced hypertension (PIH) were randomly allocated to one of three treatment groups: A: hydralazine (13); B: hydralazine and propranolol (17); and C: hydralazine and pindolol (19)." | 5.08 | Beta-adrenergic blocking agents in the treatment of pregnancy-induced hypertension. ( Holzberg, G; Insler, V; Mazor, M; Paran, E; Zmora, E, 1995) |
| "To evaluate the short-term effects of intravenously given atenolol and pindolol on utero- and umbilicoplacental vascular impedance, fetal hemodynamics and cardiac function in patients suffering from pregnancy-induced hypertension." | 5.08 | Uterine and fetal hemodynamics and fetal cardiac function after atenolol and pindolol infusion. A randomized study. ( Jouppila, P; Räsänen, J, 1995) |
| "29 women with pregnancy induced hypertension in the third trimester, 13 randomised to atenolol and 16 to pindolol." | 5.07 | Randomised controlled trial of atenolol and pindolol in human pregnancy: effects on fetal haemodynamics. ( Ingemarsson, I; Marsál, K; Montan, S; Sjöberg, NO, 1992) |
| "Thirty-two consecutive women with pregnancy-induced hypertension of early onset were randomly allocated to treatment with pindolol or methyldopa." | 5.06 | Management of pregnancy-induced hypertension with pindolol--comparative study with methyldopa. ( Anderman, S; Davidson, A; Ellenbogen, A; Grunstein, S; Jaschevatzky, O, 1986) |
| "Forty-four consecutive patients referred for treatment because of hypertension (greater than 150/90 mmHg) occurring during pregnancy were randomly allocated to one of two treatment groups, hydralazine alone (n = 21) or hydralazine combined with pindolol (n = 23)." | 5.06 | Treatment of hypertension during pregnancy with hydralazine monotherapy or with combined therapy with hydralazine and pindolol. ( Boner, G; Bott-Kanner, G; Friedman, S; Merlob, P; Nissenkorn, A; Ovadia, J; Paran, E; Reisner, S; Rosenfeld, J; Zmora, E, 1986) |
| " The incidence of severe hypertension was significantly lower when nifedipine (odds ratio, 0." | 5.05 | Comparative efficacy and safety of oral antihypertensive agents in pregnant women with chronic hypertension: a network metaanalysis. ( Bellos, I; Daskalakis, G; Loutradis, D; Papapanagiotou, A; Pergialiotis, V, 2020) |
| "Nine patients taking oral doses of 10 mg/12 h rac-pindolol as part of their treatment for hypertension in pregnancy were recruited for the study." | 3.71 | Enantioselectivity in the steady-state pharmacokinetics and transplacental distribution of pindolol at delivery in pregnancy-induced hypertension. ( Da Cunha, SP; Gonçalves, PV; Lanchote, VL; Matthes, Ado C, 2002) |
| " Fifteen patients with mild pre-eclampsia were chronically treated with oral pindolol." | 3.68 | The effect of acute and chronic antihypertensive therapy on maternal and fetoplacental Doppler velocimetry. ( Bjornsson, S; Cameron, AD; Fairlie, FM; Mathers, A; Walker, JJ, 1992) |
| "Renal hypertension was induced by partial clamping of both renal arteries in female Wistar rats 4 weeks before pregnancy." | 1.27 | Acute haemodynamic effects of pindolol during pregnancy in experimental renal hypertension. ( Karlsson, K; Ljungblad, U; Lundgren, Y, 1984) |
| "Pindolol was administered with the food during the entire pregnancy period." | 1.27 | Hemodynamic changes after chronic pindolol administration in pregnant renal hypertensive rats. ( Karlsson, K; Ljungblad, U; Lundgren, Y, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (64.71) | 18.7374 |
| 1990's | 4 (23.53) | 18.2507 |
| 2000's | 1 (5.88) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Bellos, I | 1 |
| Pergialiotis, V | 1 |
| Papapanagiotou, A | 1 |
| Loutradis, D | 1 |
| Daskalakis, G | 1 |
| Gonçalves, PV | 1 |
| Matthes, Ado C | 1 |
| Da Cunha, SP | 1 |
| Lanchote, VL | 1 |
| Moses, JW | 1 |
| Borer, JS | 1 |
| Dubois, D | 2 |
| Petitcolas, J | 2 |
| Temperville, B | 1 |
| Klepper, A | 1 |
| Catherine, P | 1 |
| Ingemarsson, I | 3 |
| Liedholm, H | 1 |
| Montan, S | 2 |
| Westgren, M | 1 |
| Melander, A | 1 |
| Lundgren, Y | 2 |
| Karlsson, K | 2 |
| Ljungblad, U | 2 |
| Paran, E | 2 |
| Holzberg, G | 1 |
| Mazor, M | 1 |
| Zmora, E | 2 |
| Insler, V | 1 |
| Räsänen, J | 1 |
| Jouppila, P | 1 |
| Monnier, JC | 1 |
| Honore, P | 1 |
| Lanciaux, B | 1 |
| Boulogne, M | 1 |
| Walker, JJ | 1 |
| Mathers, A | 1 |
| Bjornsson, S | 1 |
| Cameron, AD | 1 |
| Fairlie, FM | 1 |
| Marsál, K | 1 |
| Sjöberg, NO | 1 |
| Kawecka-Jaszcz, K | 1 |
| Skoczeń, M | 1 |
| Ellenbogen, A | 1 |
| Jaschevatzky, O | 1 |
| Davidson, A | 1 |
| Anderman, S | 1 |
| Grunstein, S | 1 |
| Adaikan, PG | 1 |
| Arulkumaran, S | 1 |
| Kottegoda, SR | 1 |
| Rosenfeld, J | 1 |
| Bott-Kanner, G | 1 |
| Boner, G | 1 |
| Nissenkorn, A | 1 |
| Friedman, S | 1 |
| Ovadia, J | 1 |
| Merlob, P | 1 |
| Reisner, S | 1 |
3 reviews available for pindolol and Cardiovascular Pregnancy Complications
| Article | Year |
|---|---|
Comparative efficacy and safety of oral antihypertensive agents in pregnant women with chronic hypertension: a network metaanalysis.
Topics: Abruptio Placentae; Amlodipine; Antihypertensive Agents; Atenolol; Cesarean Section; Chronic Disease | 2020 |
Beta-adrenergic antagonists in the treatment of patients with heart disease.
Topics: Acebutolol; Adrenergic beta-Agonists; Alprenolol; Animals; Arrhythmias, Cardiac; Bronchial Spasm; Ca | 1981 |
[Beta-blockaders in the treatment of hypertension in pregnancy].
Topics: Adrenergic beta-Antagonists; Atenolol; Drug Evaluation; Female; Humans; Hypertension; Metoprolol; Ox | 1985 |
5 trials available for pindolol and Cardiovascular Pregnancy Complications
| Article | Year |
|---|---|
Beta-adrenergic blocking agents in the treatment of pregnancy-induced hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Blood Glucose; Blood Pressure; Drug Therapy, Combination; Female | 1995 |
Uterine and fetal hemodynamics and fetal cardiac function after atenolol and pindolol infusion. A randomized study.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Atenolol; Female; Fetal Heart; Hemodyna | 1995 |
Randomised controlled trial of atenolol and pindolol in human pregnancy: effects on fetal haemodynamics.
Topics: Atenolol; Blood Pressure; Double-Blind Method; Female; Fetus; Heart Rate; Hemodynamics; Humans; Hype | 1992 |
Management of pregnancy-induced hypertension with pindolol--comparative study with methyldopa.
Topics: Adult; Female; Fetus; Humans; Hypertension; Methyldopa; Pindolol; Pregnancy; Pregnancy Complications | 1986 |
Treatment of hypertension during pregnancy with hydralazine monotherapy or with combined therapy with hydralazine and pindolol.
Topics: Adult; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Pindolo | 1986 |
9 other studies available for pindolol and Cardiovascular Pregnancy Complications
| Article | Year |
|---|---|
Enantioselectivity in the steady-state pharmacokinetics and transplacental distribution of pindolol at delivery in pregnancy-induced hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Female; Humans; Hypertension; Pindolol; | 2002 |
Treatment of hypertension in pregnancy with beta-adrenoceptor antagonists.
Topics: Abnormalities, Drug-Induced; Acebutolol; Adrenergic beta-Antagonists; Adult; Apgar Score; Atenolol; | 1982 |
Fetal heart rate during treatment of maternal hypertension with beta-adrenergic antagonists. A preliminary report.
Topics: Adrenergic beta-Antagonists; Atenolol; Female; Fetal Heart; Heart Rate; Humans; Hypertension; Pindol | 1984 |
Acute haemodynamic effects of pindolol during pregnancy in experimental renal hypertension.
Topics: Animals; Blood Pressure; Cardiac Output; Female; Heart Rate; Hemodynamics; Hypertension, Renal; Ovar | 1984 |
Hemodynamic changes after chronic pindolol administration in pregnant renal hypertensive rats.
Topics: Animals; Blood Pressure; Body Weight; Cardiac Output; Female; Hemodynamics; Hypertension, Renal; Mat | 1983 |
[beta-blockers and high risk pregnancies. Viewpoint of the nephrologist and the obstetrician].
Topics: Acebutolol; Adrenergic beta-Antagonists; Female; Humans; Hypertension; Pindolol; Pregnancy; Pregnanc | 1978 |
[Value of hydralazine-beta blockader association in hypertension of pregnancy].
Topics: Adrenergic beta-Antagonists; Adult; Drug Therapy, Combination; Female; Fetus; Humans; Hydralazine; H | 1978 |
The effect of acute and chronic antihypertensive therapy on maternal and fetoplacental Doppler velocimetry.
Topics: Blood Pressure; Brachial Artery; Female; Fetus; Humans; Hypertension; Infant, Newborn; Nicardipine; | 1992 |
Effect of a beta-adrenoceptor antagonist, pindolol, on human uterine smooth muscle.
Topics: Adult; Blood Pressure; Female; Humans; Hypertension; In Vitro Techniques; Myometrium; Pindolol; Preg | 1987 |