pindolol has been researched along with Cardiomyopathy, Congestive in 14 studies
Pindolol: A moderately lipophilic beta blocker (ADRENERGIC BETA-ANTAGONISTS). It is non-cardioselective and has intrinsic sympathomimetic actions, but little membrane-stabilizing activity. (From Martindale, The Extra Pharmocopoeia, 30th ed, p638)
pindolol : A member of the class of indols which is the 2-hydroxy-3-(isopropylamino)propyl ether derivative of 1H-indol-4-ol.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Carvedilol is a high-affinity, slightly beta 1-selective competitive beta-blocking agent, with a KD for beta 1-receptors of approximately 4-5 nM and a selectivity of sixfold to 39-fold for beta 1-receptors rather than beta 2-receptors, depending on the method used to assess subtype potency." | 1.28 | Receptor pharmacology of carvedilol in the human heart. ( Bristow, MR; Handwerger, D; Klein, J; Larrabee, P; Minobe, W; Müller-Beckmann, B; Port, JD; Roden, R; Skerl, L, 1992) |
| "Administration of P to patients with dilated cardiomyopathy may protect against the effects of high circulating catecholamines and at the same time partially maintain intrinsic left ventricular function." | 1.27 | Acute hemodynamic and neurohumoral effects of pindolol: a beta-adrenoceptor antagonist with high intrinsic sympathomimetic activity in patients with dilated cardiomyopathy. ( Majid, PA; Morris, WM; Nishizaki, S; Niznick, J; Sole, MJ, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (28.57) | 18.7374 |
| 1990's | 10 (71.43) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Elnatan, J | 1 |
| Molenaar, P | 1 |
| Rosenfeldt, FL | 1 |
| Summers, RJ | 1 |
| Brodde, OE | 1 |
| Vogelsang, M | 1 |
| Broede, A | 1 |
| Michel-Reher, M | 1 |
| Beisenbusch-Schäfer, E | 1 |
| Hakim, K | 1 |
| Zerkowski, HR | 1 |
| Nozawa, T | 1 |
| Igawa, A | 1 |
| Yoshida, N | 1 |
| Maeda, M | 1 |
| Inoue, M | 1 |
| Yamamura, Y | 1 |
| Asanoi, H | 1 |
| Inoue, H | 1 |
| Bristow, MR | 5 |
| Minobe, W | 4 |
| Rasmussen, R | 1 |
| Larrabee, P | 4 |
| Skerl, L | 4 |
| Klein, JW | 1 |
| Anderson, FL | 2 |
| Murray, J | 2 |
| Mestroni, L | 1 |
| Karwande, SV | 1 |
| Steinfath, M | 1 |
| von der Leyen, H | 1 |
| Hecht, A | 1 |
| Neumann, KH | 1 |
| Schmitz, W | 1 |
| Scholz, H | 1 |
| Haverich, A | 1 |
| Heublein, B | 1 |
| Müller-Beckmann, B | 2 |
| Roden, R | 2 |
| Klein, J | 2 |
| Handwerger, D | 2 |
| Port, JD | 3 |
| Hershberger, RE | 1 |
| O'Connell, JB | 1 |
| Renlund, DG | 1 |
| Volkman, K | 1 |
| Böhm, M | 1 |
| Gierschik, P | 1 |
| Schnabel, P | 1 |
| Erdmann, E | 1 |
| Rasmussen, RP | 1 |
| Majid, PA | 2 |
| Niznick, J | 2 |
| Nishizaki, S | 2 |
| Morris, WM | 2 |
| Sole, MJ | 2 |
| Shanes, JG | 1 |
| Wolfkiel, C | 1 |
| Ghali, J | 1 |
| Dierenfeldt, BJ | 1 |
| Kondos, GT | 1 |
| Bauman, JL | 1 |
| Binkley, PF | 1 |
| Lewe, RF | 1 |
| Lima, JJ | 1 |
| Al-Awwa, A | 1 |
| Unverferth, DV | 1 |
| Leier, CV | 1 |
1 trial available for pindolol and Cardiomyopathy, Congestive
| Article | Year |
|---|---|
Acute hemodynamic effects of pindolol and propranolol in patients with dilated cardiomyopathy: relevance of intrinsic sympathomimetic activity.
Topics: Adult; Cardiac Catheterization; Cardiomyopathy, Dilated; Double-Blind Method; Female; Hemodynamics; | 1988 |
13 other studies available for pindolol and Cardiomyopathy, Congestive
| Article | Year |
|---|---|
Autoradiographic localization and quantitation of beta 1- and beta 2-adrenoceptors in the human atrioventricular conducting system: a comparison of patients with idiopathic dilated cardiomyopathy and ischemic heart disease.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Atrioventricular Node; Binding, Competitive; Bundle of His | 1994 |
Diminished responsiveness of Gs-coupled receptors in severely failing human hearts: no difference in dilated versus ischemic cardiomyopathy.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adult; Cardiomyopathy, Dilated; Female; GTP-Binding Pro | 1998 |
Dual-tracer assessment of coupling between cardiac sympathetic neuronal function and downregulation of beta-receptors during development of hypertensive heart failure of rats.
Topics: 3-Iodobenzylguanidine; Animals; Autoradiography; Cardiomyopathy, Dilated; Cell Membrane; Down-Regula | 1998 |
Beta-adrenergic neuroeffector abnormalities in the failing human heart are produced by local rather than systemic mechanisms.
Topics: Adenylyl Cyclases; Adult; Cardiomyopathy, Dilated; Catecholamines; Female; Heart; Heart Failure; Hum | 1992 |
Decrease in beta 1- and increase in beta 2-adrenoceptors in long-term follow-up after orthotopic cardiac transplantation.
Topics: Adult; Biopsy; Cardiac Catheterization; Cardiomyopathy, Dilated; Down-Regulation; Female; Follow-Up | 1992 |
Effects of carvedilol on adrenergic receptor pharmacology in human ventricular myocardium and lymphocytes.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Binding, Competitive; Carbazoles; Cardiomyopat | 1992 |
Receptor pharmacology of carvedilol in the human heart.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Binding, Competitive; Carbazoles; Cardiomyopat | 1992 |
Differences in beta-adrenergic neuroeffector mechanisms in ischemic versus idiopathic dilated cardiomyopathy.
Topics: Adenylyl Cyclases; Adult; Cardiomyopathy, Dilated; Catecholamines; Creatine Kinase; Down-Regulation; | 1991 |
Myocardial beta-adrenoceptors and inhibitory G-proteins in myocardial biopsies and in explanted hearts from patients with dilated cardiomyopathy.
Topics: Biopsy; Cardiomyopathy, Dilated; Down-Regulation; GTP-Binding Proteins; Heart; Humans; Immunoblottin | 1990 |
Calcium antagonist binding sites in failing and nonfailing human ventricular myocardium.
Topics: Calcium Channel Blockers; Calcium Channels; Cardiomyopathy, Dilated; Cell Membrane; Humans; Iodocyan | 1990 |
Acute hemodynamic and neurohumoral effects of pindolol: a beta-adrenoceptor antagonist with high intrinsic sympathomimetic activity in patients with dilated cardiomyopathy.
Topics: Adult; Cardiomyopathy, Dilated; Catecholamines; Female; Hemodynamics; Humans; Male; Middle Aged; Pin | 1987 |
Hemodynamic-inotropic response to beta-blocker with intrinsic sympathomimetic activity in patients with congestive cardiomyopathy.
Topics: Adult; Cardiac Catheterization; Cardiomyopathy, Dilated; Depression, Chemical; Drug Evaluation; Exer | 1986 |
Favorable effects of pindolol in dilated cardiomyopathy.
Topics: Cardiomyopathy, Dilated; Humans; Male; Middle Aged; Norepinephrine; Pindolol | 1986 |