pindolol has been researched along with Bipolar Disorder in 13 studies
Pindolol: A moderately lipophilic beta blocker (ADRENERGIC BETA-ANTAGONISTS). It is non-cardioselective and has intrinsic sympathomimetic actions, but little membrane-stabilizing activity. (From Martindale, The Extra Pharmocopoeia, 30th ed, p638)
pindolol : A member of the class of indols which is the 2-hydroxy-3-(isopropylamino)propyl ether derivative of 1H-indol-4-ol.
Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5 mg/day or placebo for nine days in combination with three consecutive TSD cycles." | 2.69 | Sustained antidepressant effect of sleep deprivation combined with pindolol in bipolar depression. A placebo-controlled trial. ( Barbini, B; Benedetti, F; Campori, E; Colombo, C; Smeraldi, E, 1999) |
| "Despite the prevalence and morbidity of bipolar depression, few randomized treatment trials have been conducted to assess clinical efficacy." | 2.42 | Acceleration and augmentation strategies for treating bipolar depression. ( Altshuler, LL; Frye, MA; Gitlin, MJ, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (23.08) | 18.7374 |
| 1990's | 7 (53.85) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Altshuler, LL | 1 |
| Frye, MA | 1 |
| Gitlin, MJ | 1 |
| Wright, AF | 1 |
| Crichton, DN | 1 |
| Loudon, JB | 1 |
| Morten, JE | 1 |
| Steel, CM | 1 |
| Young, LT | 1 |
| Li, PP | 1 |
| Kish, SJ | 1 |
| Warsh, JJ | 1 |
| Kay, G | 2 |
| Sargeant, M | 2 |
| McGuffin, P | 2 |
| Whatley, S | 2 |
| Marchbanks, R | 2 |
| Bullock, T | 1 |
| Montgomery, S | 2 |
| Elliott, JM | 2 |
| Baldwin, D | 1 |
| Kraus, RP | 1 |
| Smeraldi, E | 3 |
| Benedetti, F | 1 |
| Barbini, B | 1 |
| Campori, E | 1 |
| Colombo, C | 1 |
| Yatham, LN | 1 |
| Lint, D | 1 |
| Lam, RW | 1 |
| Zis, AP | 1 |
| Serretti, A | 2 |
| Zanardi, R | 2 |
| Rossini, D | 2 |
| Cusin, C | 2 |
| Lilli, R | 1 |
| Franchini, L | 1 |
| Lattuada, E | 1 |
| Dotoli, D | 1 |
| Jeanningros, R | 1 |
| Mazzola, P | 1 |
| Azorin, JM | 1 |
| Samuelian-Massa, C | 1 |
| Tissot, R | 1 |
| Magliozzi, JR | 1 |
| Gietzen, D | 1 |
| Maddock, RJ | 1 |
| Haack, D | 1 |
| Doran, AR | 1 |
| Goodman, T | 1 |
| Weiler, PG | 1 |
| Berrettini, WH | 1 |
| Cappellari, CB | 1 |
| Nurnberger, JI | 1 |
| Gershon, ES | 1 |
1 review available for pindolol and Bipolar Disorder
| Article | Year |
|---|---|
Acceleration and augmentation strategies for treating bipolar depression.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Bipolar | 2003 |
3 trials available for pindolol and Bipolar Disorder
| Article | Year |
|---|---|
Sustained antidepressant effect of sleep deprivation combined with pindolol in bipolar depression. A placebo-controlled trial.
Topics: Acute Disease; Adrenergic beta-Antagonists; Adult; Affect; Bipolar Disorder; Combined Modality Thera | 1999 |
Influence of tryptophan hydroxylase and serotonin transporter genes on fluvoxamine antidepressant activity.
Topics: Adult; Age of Onset; Alleles; Antidepressive Agents, Second-Generation; Bipolar Disorder; Carrier Pr | 2001 |
Factors affecting fluvoxamine antidepressant activity: influence of pindolol and 5-HTTLPR in delusional and nondelusional depression.
Topics: Adult; Antidepressive Agents; Bipolar Disorder; Carrier Proteins; Delusions; Depressive Disorder, Ma | 2001 |
9 other studies available for pindolol and Bipolar Disorder
| Article | Year |
|---|---|
Beta-adrenoceptor binding defects in cell lines from families with manic-depressive disorder.
Topics: 5'-Nucleotidase; Adolescent; Adult; B-Lymphocytes; Bipolar Disorder; Cell Line; Female; Humans; Male | 1984 |
Cerebral cortex beta-adrenoceptor binding in bipolar affective disorder.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Bipolar Disorder; Cerebral Cortex; Fema | 1994 |
The lymphoblast beta-adrenergic receptor in bipolar depressed patients: effect of chronic incubation with lithium chloride.
Topics: Adult; Aged; Bipolar Disorder; Cell Line, Transformed; Down-Regulation; Female; Humans; Iodocyanopin | 1994 |
The lymphoblast beta-adrenergic receptor in bipolar depressed patients: characterization and down-regulation.
Topics: Adenylyl Cyclases; Adult; Bipolar Disorder; Cell Line; Cyclic AMP; Down-Regulation; Female; Humans; | 1993 |
Rapid cycling triggered by pindolol augmentation of paroxetine, but not with desipramine.
Topics: Adult; Antidepressive Agents, Second-Generation; Arousal; Bipolar Disorder; Depressive Disorder; Dos | 1996 |
Adverse effects of pindolol augmentation in patients with bipolar depression.
Topics: Adrenergic beta-Antagonists; Adult; Antidepressive Agents; Bipolar Disorder; Drug Therapy, Combinati | 1999 |
Beta-adrenoceptor density of intact mononuclear leukocytes in subgroups of depressive disorders.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Bipolar Disorder; Depressive Disorder; Female; Humans; Mal | 1991 |
Lymphocyte beta-adrenoreceptor density in patients with unipolar depression and normal controls.
Topics: Adult; Aged; Bipolar Disorder; Depressive Disorder; Female; Humans; Iodocyanopindolol; Lymphocytes; | 1989 |
Beta-adrenergic receptors on lymphoblasts. A study of manic-depressive illness.
Topics: Bipolar Disorder; Cell Line; Humans; Iodocyanopindolol; Kinetics; Lymphocytes; Pindolol; Receptors, | 1987 |