pindolol has been researched along with Asthma in 46 studies
Pindolol: A moderately lipophilic beta blocker (ADRENERGIC BETA-ANTAGONISTS). It is non-cardioselective and has intrinsic sympathomimetic actions, but little membrane-stabilizing activity. (From Martindale, The Extra Pharmocopoeia, 30th ed, p638)
pindolol : A member of the class of indols which is the 2-hydroxy-3-(isopropylamino)propyl ether derivative of 1H-indol-4-ol.
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
Excerpt | Relevance | Reference |
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"In a parallel, double-blind, placebo-controlled study we investigated the effect of the antiallergic drug Ketotifen on bronchial resistance (determined body plethysmographically) and beta 2-adrenoceptor density of lymphocytes (determined by 125-iodo-cyano-pindolol binding) in asthmatic children suffering from exercise-induced asthma (EIA)." | 9.06 | Effects of the antiallergic drug ketotifen on bronchial resistance and beta-adrenoceptor density of lymphocytes in children with exercise-induced asthma. ( Braun, D; Griese, M; Kusenbach, G; Ludwig, J; Reinhardt, D, 1988) |
"In 11 asthmatic subjects the relative magnitude and the site of airway bronchoconstriction were compared after the oral administration of 40 mg of propranolol and 2." | 9.05 | Beta-blockers in bronchial asthma: effect of propranolol and pindolol on large and small airways. ( Argiropoulou, V; Louridas, G; Patakas, D; Tsara, V, 1983) |
"In a controlled double-blind crossover trial of 5 mg mepindolol versus 80 mg propranolol, 15 mg pindolol or placebo given as single oral doses in 16 asthmatic patients, respiratory function and cardiovascular parameters were measured simultaneously." | 9.04 | Comparative investigation of the respiratory and cardiovascular effect of mepindolol, propranolol and pindolol in asthmatic patients. ( Beumer, HM; Teirlinck, C; Wiseman, RA, 1978) |
"The effect of a single oral dose of pindolol on bronchi was studied in a double-blind cross-over trial in 20 adult patients, most of whom had moderate bronchial asthma." | 9.04 | Influence of pindolol (Visken) on respiratory function in 20 asthmatic patients. ( Boye, NP; Christensen, CC; Erikson, H; Hansen, G, 1978) |
"Plasma histamine, cortisol, epinephrine, cyclic adenosine monophosphate (cAMP), and leukocyte beta-adrenergic receptors were measured in asthmatic patients with (n = 7) and without (n = 10) nocturnal asthma at 4 PM and 4 AM and compared with those of normal subjects (n = 10)." | 7.68 | Plasma histamine, epinephrine, cortisol, and leukocyte beta-adrenergic receptors in nocturnal asthma. ( Ando, R; Cicutto, LC; Hill, MR; Martin, RJ; Surs, W; Szefler, SJ, 1991) |
"Pindolol was administered gradually by mouth (2." | 6.66 | Influence of pindolol on asthmatics and effect of bronchodilators. ( Antoniadou, H; Georgopoulos, D; Giulekas, D; Papakosta, D; Sotiropoulou, E; Vamvalis, C, 1986) |
"In a parallel, double-blind, placebo-controlled study we investigated the effect of the antiallergic drug Ketotifen on bronchial resistance (determined body plethysmographically) and beta 2-adrenoceptor density of lymphocytes (determined by 125-iodo-cyano-pindolol binding) in asthmatic children suffering from exercise-induced asthma (EIA)." | 5.06 | Effects of the antiallergic drug ketotifen on bronchial resistance and beta-adrenoceptor density of lymphocytes in children with exercise-induced asthma. ( Braun, D; Griese, M; Kusenbach, G; Ludwig, J; Reinhardt, D, 1988) |
"In 11 asthmatic subjects the relative magnitude and the site of airway bronchoconstriction were compared after the oral administration of 40 mg of propranolol and 2." | 5.05 | Beta-blockers in bronchial asthma: effect of propranolol and pindolol on large and small airways. ( Argiropoulou, V; Louridas, G; Patakas, D; Tsara, V, 1983) |
"In a controlled double-blind crossover trial of 5 mg mepindolol versus 80 mg propranolol, 15 mg pindolol or placebo given as single oral doses in 16 asthmatic patients, respiratory function and cardiovascular parameters were measured simultaneously." | 5.04 | Comparative investigation of the respiratory and cardiovascular effect of mepindolol, propranolol and pindolol in asthmatic patients. ( Beumer, HM; Teirlinck, C; Wiseman, RA, 1978) |
"The effect of a single oral dose of pindolol on bronchi was studied in a double-blind cross-over trial in 20 adult patients, most of whom had moderate bronchial asthma." | 5.04 | Influence of pindolol (Visken) on respiratory function in 20 asthmatic patients. ( Boye, NP; Christensen, CC; Erikson, H; Hansen, G, 1978) |
"Plasma histamine, cortisol, epinephrine, cyclic adenosine monophosphate (cAMP), and leukocyte beta-adrenergic receptors were measured in asthmatic patients with (n = 7) and without (n = 10) nocturnal asthma at 4 PM and 4 AM and compared with those of normal subjects (n = 10)." | 3.68 | Plasma histamine, epinephrine, cortisol, and leukocyte beta-adrenergic receptors in nocturnal asthma. ( Ando, R; Cicutto, LC; Hill, MR; Martin, RJ; Surs, W; Szefler, SJ, 1991) |
" The autoradiographic distribution of alpha 1-adrenoceptors was investigated in non-diseased and asthmatic human lung by use of [3H]-prazosin (H-PZ)." | 3.67 | Alpha 1-adrenoceptor function and autoradiographic distribution in human asthmatic lung. ( Goldie, RG; Paterson, JW; Rigby, PJ; Spina, D, 1989) |
"The autoradiographic distribution and density of beta-adrenoceptors in human non-diseased and asthmatic bronchi were investigated using [125I]iodocyanopindolol (I-CYP)." | 3.67 | Autoradiographic localization of beta-adrenoceptors in asthmatic human lung. ( Goldie, RG; Paterson, JW; Rigby, PJ; Spina, D, 1989) |
"Beta-adrenoceptor binding in lymphocytes of asthmatic and non-asthmatic children and healthy adult volunteers was investigated with the radioligand 125-iodocyanopindolol (ICYP)." | 3.67 | Beta-adrenoceptor density and resolution of high and low affinity state on B- and T-cells in asthmatic and non-asthmatic children. ( Griese, M; Körholz, D; Reifenhäuser, A; Reinhardt, D; Seeger, K; Wahn, V, 1988) |
"The beta-adrenergic receptor binding sites on peripheral lymphocytes in children with bronchial asthma (n = 16) and seasonal allergic rhinitis (n = 8) were examined in comparison with normal controls (n = 18) by means of 124I-cyanopindolol." | 3.67 | Beta-adrenergic receptors of lymphocytes in children with allergic respiratory diseases. ( Bittera, I; Eck, E; Falkay, G; Gyurkovits, K; Koltai, M, 1988) |
"In two groups of patients with well-defined obstructive lung disease - a group of bronchitics according to WHO criteria and a group of patients with extrinsic allergic asthma - the effect of carazolol, a so-called non-cardioselective beta-blocking drug, was investigated." | 3.66 | beta 1 Selectivity of drugs: quality of the drug or quality of the patient? ( Perkow, I; Teufel, W; von Wichert, P, 1980) |
"Pindolol was administered gradually by mouth (2." | 2.66 | Influence of pindolol on asthmatics and effect of bronchodilators. ( Antoniadou, H; Georgopoulos, D; Giulekas, D; Papakosta, D; Sotiropoulou, E; Vamvalis, C, 1986) |
"Procaterol treatment reduced (p less than 0." | 2.66 | The effect of procaterol treatment on beta-adrenergic bronchodilation and polymorphonuclear leukocyte responsiveness. ( Arbabian, M; Borgen, L; Busse, WW; Ruoho, A; Sharpe, G; Smith, A, 1985) |
"6 Atenolol 60 mg was the only drug to allow a fenoterol airway response similar to placebo." | 2.65 | Assessment of beta-adrenoceptor antagonists in asthmatic patients. ( Alpers, JH; Crockett, AJ; Latimer, KM; McIntyre, EL; Ruffin, RE; Ward, HE, 1982) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 41 (89.13) | 18.7374 |
1990's | 5 (10.87) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Reinhardt, D | 3 |
Zehmisch, T | 1 |
Becker, B | 1 |
Nagel-Hiemke, M | 1 |
von Wichert, P | 1 |
Perkow, I | 1 |
Teufel, W | 1 |
Ruffin, RE | 1 |
McIntyre, EL | 1 |
Latimer, KM | 1 |
Ward, HE | 1 |
Crockett, AJ | 1 |
Alpers, JH | 1 |
McDevitt, DG | 1 |
Basran, GS | 1 |
Ball, AJ | 1 |
Hanson, JM | 1 |
Morley, J | 1 |
Turner-Warwick, M | 1 |
Venter, JC | 2 |
Fraser, CM | 2 |
Harrison, LC | 1 |
Soiefer, AI | 1 |
Jeffrey, DR | 1 |
Strauss, WL | 1 |
Charlton, RR | 1 |
Greguski, R | 1 |
Patakas, D | 1 |
Argiropoulou, V | 1 |
Louridas, G | 1 |
Tsara, V | 1 |
Cannon, RE | 1 |
Slavin, RG | 1 |
Gonasun, LM | 1 |
Sue, DY | 2 |
Hansen, JE | 2 |
Wasserman, K | 2 |
Smith, SC | 1 |
Spector, SL | 1 |
Marcelle, R | 1 |
Juchmés, J | 1 |
Lecomte, J | 1 |
Newnham, DM | 1 |
Coutie, WJ | 1 |
McFarlane, LC | 1 |
Lipworth, BJ | 1 |
Potter, PC | 1 |
Van Wyk, L | 1 |
White, D | 1 |
Dakers, BS | 1 |
Chung, FZ | 1 |
Dowdle, EB | 1 |
Hataoka, I | 1 |
Okayama, M | 1 |
Sugi, M | 1 |
Inoue, H | 1 |
Takishima, T | 1 |
Shirato, K | 1 |
Beumer, HM | 2 |
Teirlinck, C | 1 |
Wiseman, RA | 1 |
Hugues, FC | 1 |
Julien, D | 1 |
Munera, Y | 1 |
Marche, J | 1 |
Von Graffenried, B | 1 |
Schindl, R | 1 |
Christensen, CC | 1 |
Boye, NP | 1 |
Erikson, H | 1 |
Hansen, G | 1 |
Hellström, PE | 1 |
Salonen, T | 1 |
Mattson, K | 1 |
Poppius, H | 1 |
Gavrilescu, S | 1 |
Szefler, SJ | 1 |
Ando, R | 1 |
Cicutto, LC | 1 |
Surs, W | 1 |
Hill, MR | 1 |
Martin, RJ | 1 |
Sharma, RK | 1 |
Jeffery, PK | 1 |
Kokubu, F | 1 |
Adachi, M | 1 |
Takahashi, T | 1 |
Odagiri, T | 1 |
Abe, Y | 1 |
Mano, K | 1 |
Spina, D | 3 |
Rigby, PJ | 3 |
Paterson, JW | 3 |
Goldie, RG | 3 |
Körholz, D | 1 |
Seeger, K | 1 |
Griese, M | 2 |
Wahn, V | 1 |
Reifenhäuser, A | 1 |
Ludwig, J | 1 |
Braun, D | 1 |
Kusenbach, G | 1 |
Böhm, E | 1 |
Fabel, H | 1 |
Bittera, I | 1 |
Gyurkovits, K | 1 |
Falkay, G | 1 |
Eck, E | 1 |
Koltai, M | 1 |
Giulekas, D | 1 |
Georgopoulos, D | 1 |
Papakosta, D | 1 |
Antoniadou, H | 1 |
Sotiropoulou, E | 1 |
Vamvalis, C | 1 |
Chan, SC | 1 |
Hanifin, JM | 1 |
Holden, CA | 1 |
Thompson, WJ | 1 |
Hirshman, CA | 1 |
Busse, WW | 1 |
Sharpe, G | 1 |
Smith, A | 1 |
Arbabian, M | 1 |
Borgen, L | 1 |
Ruoho, A | 1 |
Papadimitriou, JM | 1 |
Self, HM | 1 |
Greenberg, MA | 1 |
Birx, DL | 1 |
Gross, F | 1 |
Monteiro Trindade, A | 1 |
Costa Trindade, J | 2 |
Palma-Carlos, AG | 2 |
Monteiro Trinidade, A | 1 |
Palma Carlos, AC | 1 |
De Pádua, F | 2 |
Monteiro-Trindade, A | 1 |
Costa-Trindade, J | 1 |
Simpson, FO | 1 |
Sentissi, M | 1 |
Schrijen, F | 1 |
Sadoul, P | 1 |
Meier, J | 1 |
Baranowski, E | 1 |
Wagner, E | 1 |
2 reviews available for pindolol and Asthma
Article | Year |
---|---|
Adverse effects of beta-adrenergic receptor blocking drugs on respiratory function.
Topics: Adrenergic beta-Antagonists; Alprenolol; Asthma; Bronchi; Bronchial Spasm; Humans; Isoproterenol; Mu | 1974 |
Beta-adrenergic receptor blocking drugs in hypertension.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alprenolol; Antidepressive Agents; Antihy | 1974 |
13 trials available for pindolol and Asthma
Article | Year |
---|---|
Assessment of beta-adrenoceptor antagonists in asthmatic patients.
Topics: Adrenergic beta-Antagonists; Adult; Asthma; Atenolol; Female; Forced Expiratory Volume; Humans; Male | 1982 |
Beta-blockers in bronchial asthma: effect of propranolol and pindolol on large and small airways.
Topics: Adult; Asthma; Bronchi; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Maximal | 1983 |
beta-Adrenergic blockade with pindolol (LB-46) in mild to moderate asthma.
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Female; Forced Expiratory Volume; Heart Rate; H | 1981 |
Comparative investigation of the respiratory and cardiovascular effect of mepindolol, propranolol and pindolol in asthmatic patients.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Asthma; Blood Pressure; Female; Forced Expiratory Volume; | 1978 |
[Study of the respiratory tolerance of adrenolytic beta-blockers in the asthmatic].
Topics: Adrenergic beta-Antagonists; Adult; Asthma; Atenolol; Bronchial Spasm; Female; Forced Expiratory Vol | 1978 |
[Competitive effects of pindolol and salbutamol on airway resistance in asthmatics].
Topics: Adrenergic beta-Antagonists; Adult; Aerosols; Airway Resistance; Albuterol; Asthma; Bronchi; Drug Th | 1978 |
Influence of pindolol (Visken) on respiratory function in 20 asthmatic patients.
Topics: Adolescent; Adult; Asthma; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Fo | 1978 |
[Therapeutic differences between atenolol and pindolol in asthmatic patients].
Topics: Asthma; Atenolol; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Hemodynamics; Huma | 1979 |
Effects of the antiallergic drug ketotifen on bronchial resistance and beta-adrenoceptor density of lymphocytes in children with exercise-induced asthma.
Topics: Adolescent; Airway Resistance; Asthma; Bronchi; Child; Female; Humans; Immunoglobulin E; Iodocyanopi | 1988 |
[Changes in lung function following administration of eyedrops containing timolol, metipranolol, pindolol and pilocarpine in healthy probands and patients with mild bronchial asthma].
Topics: Airway Resistance; Asthma; Bronchial Spasm; Clinical Trials as Topic; Double-Blind Method; Humans; L | 1987 |
Influence of pindolol on asthmatics and effect of bronchodilators.
Topics: Adolescent; Adult; Albuterol; Asthma; Bronchial Spasm; Bronchodilator Agents; Child; Female; Forced | 1986 |
The effect of procaterol treatment on beta-adrenergic bronchodilation and polymorphonuclear leukocyte responsiveness.
Topics: Adult; Asthma; Bronchodilator Agents; Cyclic AMP; Dose-Response Relationship, Drug; Double-Blind Met | 1985 |
[Beta-adrenergic block and ventilatory function. Clinical aspects].
Topics: Acetanilides; Adrenergic beta-Antagonists; Aged; Amino Alcohols; Asthma; Bronchitis; Chronic Disease | 1973 |
31 other studies available for pindolol and Asthma
Article | Year |
---|---|
Age-dependency of alpha- and beta-adrenoceptors on thrombocytes and lymphocytes of asthmatic and nonasthmatic children.
Topics: Adolescent; Adult; Aging; Albuterol; Asthma; Blood Platelets; Child; Child, Preschool; Humans; Infan | 1984 |
beta 1 Selectivity of drugs: quality of the drug or quality of the patient?
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Airway Resistance; Asthma; Blood Pressure; Bro | 1980 |
Beta-adrenoceptor blocking drugs and partial agonist activity. Is it clinically relevant?
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Asthma; Bradycardia; Cardiac Output; Heart Fa | 1983 |
Circulating beta-adrenoceptor blocking factors in asthma.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Antagonists; Asthma; Binding Sites; Eosinophilia; Humans; L | 1984 |
Autoantibodies to beta 2-adrenergic receptors: a possible cause of adrenergic hyporesponsiveness in allergic rhinitis and asthma.
Topics: Asthma; Autoantibodies; Epitopes; Humans; Lung; Myocardium; Pindolol; Receptors, Adrenergic; Recepto | 1980 |
Autoantibodies and monoclonal antibodies to beta-adrenergic receptors: their use in receptor purification and characterization.
Topics: Animals; Antibodies, Monoclonal; Asthma; Autoantibodies; Chromatography, Affinity; Erythrocyte Membr | 1981 |
The effect on asthma of a new beta blocker, pindolol.
Topics: Adult; Asthma; Bronchial Provocation Tests; Double-Blind Method; Humans; Isoproterenol; Pindolol; Pu | 1982 |
The value of exercise in testing beta blockade and airway reactivity in asthmatic patients.
Topics: Adolescent; Adult; Asthma; Bronchial Spasm; Double-Blind Method; Female; Heart Rate; Humans; Male; M | 1982 |
Cardio-selective beta-adrenergic therapy in a patient with asthma and hypertrophic obstructive cardiomyopathy.
Topics: Adult; Albuterol; Asthma; Cardiomyopathy, Hypertrophic; Female; Heart; Humans; Male; Pindolol | 1981 |
[Possible bronchomotor effects of pindolol].
Topics: Asthma; Bronchi; Bronchodilator Agents; Humans; Pindolol | 1981 |
Comparison of parameters of in vitro lymphocyte beta 2-adrenoceptor function in normal and asthmatic subjects.
Topics: Adrenergic beta-Agonists; Adult; Asthma; Cyclic AMP; Female; Forced Expiratory Volume; Humans; In Vi | 1993 |
Absence of functional inhibition of cloned human beta 2-adrenergic receptors by autoantibodies in asthmatic subjects.
Topics: Adrenergic beta-Agonists; Adult; Animals; Asthma; Autoantibodies; Child; Cloning, Molecular; Cyclic | 1993 |
Decrease in beta-adrenergic receptors of lymphocytes in spontaneously occurring acute asthma.
Topics: Acute Disease; Adolescent; Adult; Aged; Asthma; Forced Expiratory Volume; Humans; Iodocyanopindolol; | 1993 |
[Exercise-induced-asthma (author's transl)].
Topics: Adolescent; Airway Resistance; Asthma; Bronchi; Hexoprenaline; Histamine; Humans; Ipratropium; Muscl | 1977 |
Controlled study of the bronchoconstriction effect of pindolol administered intravenously or orally to patients with unstable asthma.
Topics: Administration, Oral; Adult; Airway Resistance; Asthma; Bronchial Spasm; Female; Forced Expiratory V | 1978 |
[Comparison between the respiratory effect of two beta adrenergic blocking drugs (practolol and prindolol)(author's transl)].
Topics: Asthma; Blood Pressure; Exercise Test; Forced Expiratory Volume; Heart Rate; Hemodynamics; Humans; O | 1975 |
Plasma histamine, epinephrine, cortisol, and leukocyte beta-adrenergic receptors in nocturnal asthma.
Topics: Asthma; Binding, Competitive; Cell Separation; Chromatography, High Pressure Liquid; Circadian Rhyth | 1991 |
Airway beta-adrenoceptor number in cystic fibrosis and asthma.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Asthma; Bronchi; Bronchial Neoplasms; Bronchie | 1990 |
[Study of development of autoantibody to beta-adrenergic receptors in asthmatics].
Topics: Animals; Asthma; Autoantibodies; Dogs; Female; Humans; Male; Pindolol; Radioligand Assay; Receptors, | 1989 |
Alpha 1-adrenoceptor function and autoradiographic distribution in human asthmatic lung.
Topics: Adult; Asthma; Autoradiography; Bronchi; Carbachol; Humans; In Vitro Techniques; Iodine Radioisotope | 1989 |
Autoradiographic localization of beta-adrenoceptors in asthmatic human lung.
Topics: Asthma; Autoradiography; Humans; Iodine Radioisotopes; Iodocyanopindolol; Lung; Pindolol; Receptors, | 1989 |
Beta-adrenoceptor density and resolution of high and low affinity state on B- and T-cells in asthmatic and non-asthmatic children.
Topics: Adolescent; Albuterol; Asthma; B-Lymphocytes; Child; Child, Preschool; Humans; Infant; Iodocyanopind | 1988 |
Beta-adrenergic receptors of lymphocytes in children with allergic respiratory diseases.
Topics: Adrenergic beta-Antagonists; Asthma; Bronchial Provocation Tests; Child; Female; Humans; Immunoglobu | 1988 |
Elevated leukocyte phosphodiesterase as a basis for depressed cyclic adenosine monophosphate responses in the Basenji greyhound dog model of asthma.
Topics: Adenylyl Cyclases; Animals; Asthma; Cyclic AMP; Disease Models, Animal; Dog Diseases; Dogs; Iodine R | 1985 |
Influence of the epithelium on responsiveness of guinea-pig isolated trachea to contractile and relaxant agonists.
Topics: Acetylcholine; Animals; Asthma; Autoradiography; Carbachol; Cimetidine; Colforsin; Dose-Response Rel | 1986 |
Chronic cough in a 61-year-old female.
Topics: Asthma; Captopril; Cough; Diagnosis, Differential; Female; Humans; Middle Aged; Pindolol | 1988 |
[Current drugs. Therapy using -blockaders ( -adrenolytics)].
Topics: Acetanilides; Adrenergic beta-Antagonists; Alprenolol; Amino Alcohols; Angina Pectoris; Arrhythmias, | 1973 |
[Effect of "specific" cardiac adrenergic inhibitors on ventilatory function in bronchial asthma].
Topics: Adrenergic beta-Antagonists; Asthma; Heart; Humans; Pindolol; Respiration; Spirometry | 1973 |
[Beta-adrenergic blocking agents and ventilatory function. Clinical aspects].
Topics: Adrenergic beta-Antagonists; Asthma; Bronchitis; Humans; Pindolol; Practolol; Pulmonary Ventilation; | 1973 |
[Hemodynamic effects of practolol in chronic bronchopneumopathies].
Topics: Adult; Asthma; Bronchitis; Cardiac Volume; Chronic Disease; Drug Evaluation; Heart Rate; Hemodynamic | 1974 |
[Experimental studies on the cardio-selectivity of pindolol. Studies on healthy subjects, and patients with bronchitis and asthma].
Topics: Angina Pectoris; Arrhythmias, Cardiac; Asthma; Bronchitis; Heart; Humans; Metaproterenol; Pindolol; | 1973 |