pindolol and Anxiety
pindolol has been researched along with Anxiety in 19 studies
Pindolol: A moderately lipophilic beta blocker (ADRENERGIC BETA-ANTAGONISTS). It is non-cardioselective and has intrinsic sympathomimetic actions, but little membrane-stabilizing activity. (From Martindale, The Extra Pharmocopoeia, 30th ed, p638)
pindolol : A member of the class of indols which is the 2-hydroxy-3-(isopropylamino)propyl ether derivative of 1H-indol-4-ol.
Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "To test whether the combination of pindolol with a serotonergic antidepressant produces a synergistic increase in synaptic 5HT by examining the effects on measures of sleep, psychomotor performance and ratings of anxiety." | 5.10 | Effects on sleep architecture of pindolol, paroxetine and their combination in healthy volunteers. ( Bailey, J; Bell, C; Nutt, D; Rich, A; Wilson, S, 2003) |
| "Pindolol or a placebo was administered 90 min before a test flight and the flying and hovering performance of five students was assessed by qualified flying instructors." | 2.65 | Pilot study on the value of a beta-blocking drug in initial helicopter training. ( Donaldson, E; Grant-Thomson, J; Morwood, P; O'Connor, N; Tippett, R, 1980) |
| " +/- Pindolol, an antagonist at 5-HT1 receptors, showed a biphasic dose-response curve with a fall in entry ratio at one high dose." | 1.27 | Effects in the X-maze anxiety model of agents acting at 5-HT1 and 5-HT2 receptors. ( Critchley, MA; Handley, SL, 1987) |
Research
Studies (19)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (47.37) | 18.7374 |
| 1990's | 2 (10.53) | 18.2507 |
| 2000's | 5 (26.32) | 29.6817 |
| 2010's | 2 (10.53) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Paltian, JJ | 1 |
| Dos Reis, AS | 1 |
| de Oliveira, RL | 1 |
| da Fonseca, CAR | 1 |
| Domingues, WB | 1 |
| Dellagostin, EN | 1 |
| Campos, VF | 1 |
| Kruger, R | 1 |
| Alves, D | 1 |
| Luchese, C | 1 |
| Wilhelm, EA | 1 |
| Bernik, M | 1 |
| Ramos, RT | 1 |
| Hetem, LAB | 1 |
| Graeff, F | 1 |
| Nautiyal, KM | 1 |
| Tritschler, L | 1 |
| Ahmari, SE | 1 |
| David, DJ | 1 |
| Gardier, AM | 1 |
| Hen, R | 1 |
| Hasler, F | 1 |
| Studerus, E | 1 |
| Lindner, K | 1 |
| Ludewig, S | 1 |
| Vollenweider, FX | 1 |
| Fleminger, S | 2 |
| Greenwood, RJ | 2 |
| Oliver, DL | 2 |
| Bell, C | 1 |
| Wilson, S | 1 |
| Rich, A | 1 |
| Bailey, J | 1 |
| Nutt, D | 1 |
| Donaldson, E | 1 |
| Grant-Thomson, J | 1 |
| Morwood, P | 1 |
| O'Connor, N | 1 |
| Tippett, R | 1 |
| Krope, P | 1 |
| Kohrs, A | 1 |
| Ott, H | 1 |
| Wagner, W | 1 |
| Fichte, K | 1 |
| Oswald, WD | 1 |
| Przegaliński, E | 1 |
| Filip, M | 1 |
| Chojnacka-Wójcik, E | 1 |
| Tatarczyńska, E | 1 |
| Gurguis, GN | 1 |
| Yonkers, KA | 1 |
| Blakeley, JE | 1 |
| Phan, SP | 1 |
| Williams, A | 1 |
| Rush, AJ | 1 |
| Griebel, G | 1 |
| Rodgers, RJ | 1 |
| Perrault, G | 1 |
| Sanger, DJ | 1 |
| Scharbach, H | 1 |
| Schoenen, J | 1 |
| Delwaide, PJ | 1 |
| Koella, WP | 1 |
| Chierichetti, SM | 1 |
| Moise, G | 1 |
| Galeone, M | 1 |
| Fiorella, G | 1 |
| Lazzari, R | 1 |
| Critchley, MA | 1 |
| Handley, SL | 1 |
| Albus, M | 1 |
| Stahl, S | 1 |
| Müller-Spahn, F | 1 |
| Engel, RR | 1 |
Reviews
4 reviews available for pindolol and Anxiety
| Article | Year |
|---|---|
Pharmacological management for agitation and aggression in people with acquired brain injury.
Topics: Adrenergic beta-Antagonists; Aggression; Amantadine; Anxiety; Brain Injuries; Humans; Methylphenidat | 2003 |
Pharmacological management for agitation and aggression in people with acquired brain injury.
Topics: Adrenergic beta-Antagonists; Aggression; Amantadine; Anxiety; Brain Injuries; Humans; Methylphenidat | 2006 |
[Beta blockers as psychotropic drugs].
Topics: Adjustment Disorders; Adrenergic beta-Antagonists; Alprenolol; Anxiety; Attention; Behavior Therapy; | 1976 |
CNS-related (side-)effects of beta-blockers with special reference to mechanisms of action.
Topics: Adrenergic beta-Antagonists; Amphetamine; Animals; Anxiety; Blood-Brain Barrier; Central Nervous Sys | 1985 |
Trials
9 trials available for pindolol and Anxiety
| Article | Year |
|---|---|
Effect of single doses of pindolol and d-fenfluramine on flumazenil-induced anxiety in panic disorder patients.
Topics: Adult; Anxiety; Female; Fenfluramine; Flumazenil; GABA Modulators; Humans; Male; Middle Aged; Panic | 2019 |
Investigation of serotonin-1A receptor function in the human psychopharmacology of MDMA.
Topics: Adult; Affect; Anxiety; Cognition; Double-Blind Method; Humans; Male; N-Methyl-3,4-methylenedioxyamp | 2009 |
Effects on sleep architecture of pindolol, paroxetine and their combination in healthy volunteers.
Topics: Adult; Affect; Anxiety; Blood Pressure; Cross-Over Studies; Drug Therapy, Combination; Eye Movements | 2003 |
Pilot study on the value of a beta-blocking drug in initial helicopter training.
Topics: Adrenergic beta-Antagonists; Adult; Aerospace Medicine; Anxiety; Clinical Trials as Topic; Double-Bl | 1980 |
Evaluating mepindolol in a test model of examination anxiety in students.
Topics: Adrenergic beta-Antagonists; Adult; Anxiety; Drug Evaluation; Female; Humans; Male; Motor Activity; | 1982 |
[Anxiolysis and reduction of subjectively scaled "strain" in cognitive stress by means of pindolol].
Topics: Adult; Anxiety; Chlordiazepoxide; Drug Evaluation; Humans; Neurotic Disorders; Pindolol; Placebos; S | 1980 |
[Indications for beta-blockers in neurology].
Topics: Alcoholism; Antiparkinson Agents; Anxiety; Clinical Trials as Topic; Drug Therapy, Combination; Huma | 1978 |
Beta-blockers and psychic stress: a double-blind, placebo-controlled study of bopindolol vs lorazepam and butalbital in surgical patients.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Anxiety; Barbiturates; Clinical Trials as Topic; Double-Bl | 1985 |
Psychophysiological differentiation of two types of anxiety and its pharmacological modification by minor tranquillizer and beta-receptor-blocker.
Topics: Adult; Anti-Anxiety Agents; Anxiety; Autonomic Nervous System; Benzodiazepines; Benzodiazepinones; D | 1986 |
Other Studies
6 other studies available for pindolol and Anxiety
| Article | Year |
|---|---|
The anxiolytic effect of a promising quinoline containing selenium with the contribution of the serotonergic and GABAergic pathways: Modulation of parameters associated with anxiety in mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; GABA-A Receptor Antagonists; Male; Mice; Pindolol; Quinolines | 2020 |
A Lack of Serotonin 1B Autoreceptors Results in Decreased Anxiety and Depression-Related Behaviors.
Topics: Animals; Animals, Newborn; Anxiety; Autoreceptors; Depression; Disease Models, Animal; Exploratory B | 2016 |
The role of 5-hydroxytryptamine1A (5-HT1A) receptors in the anticonflict activity of beta-adrenoceptor antagonists.
Topics: Adrenergic beta-Antagonists; Animals; Anxiety; Betaxolol; Conflict, Psychological; Disease Models, A | 1994 |
Adrenergic receptors in premenstrual dysphoric disorder. II. Neutrophil beta2-adrenergic receptors: Gs protein coupling, phase of menstrual cycle and prediction of luteal phase symptom severity.
Topics: Adult; Anxiety; Case-Control Studies; Depression; Female; Follicular Phase; GTP-Binding Proteins; Hu | 1998 |
The effects of compounds varying in selectivity as 5-HT(1A) receptor antagonists in three rat models of anxiety.
Topics: Aminopyridines; Animals; Anxiety; Cyclohexane Monoterpenes; Diazepam; Disease Models, Animal; Dose-R | 2000 |
Effects in the X-maze anxiety model of agents acting at 5-HT1 and 5-HT2 receptors.
Topics: Animals; Anxiety; Diazepam; Disease Models, Animal; Drug Combinations; Exploratory Behavior; Male; P | 1987 |