pindolol and Aging
pindolol has been researched along with Aging in 58 studies
Pindolol: A moderately lipophilic beta blocker (ADRENERGIC BETA-ANTAGONISTS). It is non-cardioselective and has intrinsic sympathomimetic actions, but little membrane-stabilizing activity. (From Martindale, The Extra Pharmocopoeia, 30th ed, p638)
pindolol : A member of the class of indols which is the 2-hydroxy-3-(isopropylamino)propyl ether derivative of 1H-indol-4-ol.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "A large, open, multi-centre study was carried out in general practice to evaluate the effectiveness and tolerance of a combination of 10 mg pindolol plus 5 mg clopamide, in single tablet form, in the treatment of patients with essential hypertension." | 9.04 | A multi-centre general practice trial of a pindolol/clopamide combination ('Viskaldix') in essential hypertension. ( Cameron, EG; Crowder, D, 1979) |
| "A large, open, multi-centre study was carried out in general practice to evaluate the effectiveness and tolerance of a combination of 10 mg pindolol plus 5 mg clopamide, in single tablet form, in the treatment of patients with essential hypertension." | 5.04 | A multi-centre general practice trial of a pindolol/clopamide combination ('Viskaldix') in essential hypertension. ( Cameron, EG; Crowder, D, 1979) |
| "To determine the effect of aging on T3 up-regulation of beta-adrenergic receptor activity of purified synaptosomal membranes (SPM), beta-adrenergic receptor density (Bmax) and adenylyl cyclase (AC) activity were measured in young (6 months old) and aged (26 months old) male F-344 rats at baseline and after treatment with triiodothyronine (T3), 15 micrograms/100 g, intraperitoneally for 10 days." | 3.68 | 3,5,3'-L-triiodothyronine regulation of beta-adrenergic receptor density and adenylyl cyclase activity in synaptosomal membranes of aged rats. ( Mooradian, AD; Scarpace, PJ, 1993) |
| "The pharmacokinetics and beta-blocking effect of pindolol has been compared in 20 patients with essential hypertension (WHO Stage I), 10 below 25 years of age and 10 older than 60 years." | 3.67 | Beta-blocking effect and pharmacokinetics of pindolol in young and elderly hypertensive patients. ( Alván, G; Dunér, H; Garle, M; Gretzer, I; Sjöqvist, F, 1986) |
| " They were submitted to clinical exam, stress testing and plasma lipids dosage before and after four weeks of treatment." | 2.66 | [Effect of beta blockers with intrinsic sympathomimetic activity on blood pressure and blood lipids in patients with essential hypertension]. ( Bellotti, G; Braga, A; Pileggi, F; Santomauro, A; Serro-Azul, JB; Serro-Azul, LG; Wajngarten, M; Yazbek Júnior, P, 1989) |
| "1 Pharmacokinetic investigations were carried out in a group of 32 ambulant normal male volunteers in order to determine the effect of age and smoking on steady-state plasma levels of pindolol and propranolol." | 2.65 | Effects of age and smoking on the pharmacokinetics of pindolol and propranolol. ( Beveridge, T; Fitscha, P; Hitzenberger, G; Nüesch, E; Pacha, W, 1982) |
| "Steady-state pharmacokinetic parameters of the new, long-acting beta-adrenoceptor blocker bopindolol have been measured in 17 young and 20 elderly healthy men." | 1.28 | Steady state pharmacokinetics of hydrolysed bopindolol in young and elderly men. ( Holmes, D; Houle, JM; Nuesch, E; Rosenthaler, J, 1991) |
| " Although there was a statistically significant difference in certain pharmacokinetic parameters (maximum plasma concentration, area under the curve, elimination constant and elimination half-life) between elderly patients (more that 60 years) and young persons (20-30 years) no significant differences were found as far as smoking and nonsmoking is concerned." | 1.26 | Influence of smoking and age on pharmacokinetics of beta-receptor blockers. ( Beveridge, T; Fitscha, P; Hitzenberger, G; Nüesch, E; Pacha, W, 1982) |
| "Propranolol did not cause this pressor effect in prehypertensive (seven week old) SHRs." | 1.26 | Beta-adrenergic receptor blocking drugs in spontaneous hypertension. ( Levy, JV, 1976) |
Research
Studies (58)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (48.28) | 18.7374 |
| 1990's | 30 (51.72) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Reinhardt, D | 1 |
| Zehmisch, T | 1 |
| Becker, B | 1 |
| Nagel-Hiemke, M | 1 |
| Hitzenberger, G | 2 |
| Fitscha, P | 2 |
| Beveridge, T | 2 |
| Nüesch, E | 3 |
| Pacha, W | 2 |
| Feldman, RD | 1 |
| Limbird, LE | 1 |
| Nadeau, J | 1 |
| Robertson, D | 1 |
| Wood, AJ | 1 |
| Pittman, RN | 1 |
| Minneman, KP | 1 |
| Molinoff, PB | 1 |
| Duncan, PG | 1 |
| Brink, C | 1 |
| Douglas, JS | 1 |
| Kobayashi, H | 2 |
| Cazzaniga, A | 1 |
| Spano, P | 1 |
| Trabucchi, M | 2 |
| Maoret, T | 1 |
| Spano, PF | 1 |
| Brodde, OE | 1 |
| Simon, H | 1 |
| Schuppan, U | 1 |
| Erdtsieck-Ernste, EB | 1 |
| Feenstra, MG | 1 |
| Botterblom, M | 1 |
| Boer, GJ | 1 |
| Gurdal, H | 1 |
| Friedman, E | 1 |
| Johnson, MD | 1 |
| Benetos, A | 1 |
| Huguet, F | 1 |
| Albaladejo, P | 1 |
| Brisac, AM | 1 |
| Pappo, M | 1 |
| Safar, ME | 1 |
| Levy, BI | 1 |
| Bazan, A | 1 |
| Van de Velde, E | 5 |
| Fraeyman, N | 6 |
| White, M | 1 |
| Roden, R | 1 |
| Minobe, W | 1 |
| Khan, MF | 1 |
| Larrabee, P | 1 |
| Wollmering, M | 1 |
| Port, JD | 1 |
| Anderson, F | 1 |
| Campbell, D | 1 |
| Feldman, AM | 1 |
| Liu, Y | 1 |
| Jia, W | 1 |
| Strosberg, AD | 1 |
| Cynader, M | 1 |
| Pranzatelli, MR | 1 |
| Galvan, I | 1 |
| Kusumoto, FM | 1 |
| Lurie, KG | 1 |
| Dutton, J | 1 |
| Capili, H | 1 |
| Schwartz, JB | 1 |
| Mooradian, AD | 2 |
| Scarpace, PJ | 4 |
| Kennedy, AT | 1 |
| Kitchen, I | 1 |
| Hill, RG | 1 |
| Bennett-Clarke, CA | 1 |
| Leslie, MJ | 1 |
| Chiaia, NL | 1 |
| Rhoades, RW | 1 |
| Yu, O | 1 |
| Ouyang, A | 1 |
| Ujhelyi, MR | 1 |
| Bottorff, MB | 1 |
| Schur, M | 1 |
| Roll, K | 1 |
| Zhang, H | 1 |
| Stewart, J | 1 |
| Markel, ML | 1 |
| Mersmann, HJ | 1 |
| Carey, GB | 1 |
| Smith, EO | 1 |
| Collet, F | 1 |
| Féve, B | 1 |
| Frisdal, E | 1 |
| Pavoine, C | 1 |
| Pecker, F | 1 |
| Atlan, G | 1 |
| Levy, JV | 1 |
| Bylund, DB | 1 |
| Tellez-Iñon, MT | 1 |
| Hollenberg, MD | 1 |
| Bilezikian, JP | 1 |
| Gammon, DE | 1 |
| Crowder, D | 1 |
| Cameron, EG | 1 |
| Mader, SL | 1 |
| Kilfeather, SA | 1 |
| Collins, D | 1 |
| McCormack, P | 1 |
| Cotter, T | 1 |
| O'Malley, K | 1 |
| Lowenthal, DT | 1 |
| Tümer, N | 3 |
| Van Ermen, A | 1 |
| Vanscheeuwijck, P | 5 |
| Rajakumar, G | 1 |
| Koller, MM | 1 |
| Gietzen, DW | 1 |
| Goodman, TA | 1 |
| Weiler, PG | 1 |
| Graf, K | 1 |
| Fregeau, DR | 1 |
| Magliozzi, JR | 1 |
| Doran, AR | 1 |
| Maddock, RJ | 1 |
| Holmes, D | 1 |
| Houle, JM | 1 |
| Rosenthaler, J | 1 |
| Houck, WT | 2 |
| Roberts, J | 2 |
| Felder, CC | 1 |
| Piccio, MM | 1 |
| McKelvey, AM | 1 |
| Nakamura, KT | 1 |
| Robillard, JE | 1 |
| Jose, PA | 1 |
| Boehm, C | 1 |
| Borton, M | 1 |
| Docherty, JR | 1 |
| Tsujimoto, G | 1 |
| Lee, CH | 1 |
| Hoffman, BB | 1 |
| Kalaria, RN | 1 |
| Andorn, AC | 1 |
| Tabaton, M | 1 |
| Whitehouse, PJ | 1 |
| Harik, SI | 1 |
| Unnerstall, JR | 1 |
| Dax, EM | 3 |
| Ingram, DK | 1 |
| Partilla, JS | 2 |
| Gregerman, RI | 2 |
| Marchetti, B | 1 |
| Spinola, PG | 1 |
| Plante, M | 1 |
| Poyet, P | 1 |
| Folléa, N | 1 |
| Pelletier, G | 1 |
| Labrie, F | 1 |
| Serro-Azul, JB | 1 |
| Wajngarten, M | 1 |
| Santomauro, A | 1 |
| Braga, A | 1 |
| Yazbek Júnior, P | 1 |
| Bellotti, G | 1 |
| Serro-Azul, LG | 1 |
| Pileggi, F | 1 |
| Graham, SM | 1 |
| Herring, PA | 1 |
| Arinze, IJ | 1 |
| Sugden, D | 1 |
| Slesinger, PA | 1 |
| Lowenstein, PR | 1 |
| Singer, HS | 1 |
| Walker, LC | 1 |
| Casanova, MF | 1 |
| Price, DL | 1 |
| Coyle, JT | 1 |
| Gretzer, I | 1 |
| Alván, G | 1 |
| Dunér, H | 1 |
| Garle, M | 1 |
| Sjöqvist, F | 1 |
| Zahniser, NR | 1 |
| Parker, DC | 1 |
| Bier-Laning, CM | 1 |
| Miller, JA | 1 |
| Gerber, JG | 1 |
| Nies, AS | 1 |
| Bendeck, JL | 1 |
| Noguchi, A | 1 |
| Piñeyro, MA | 1 |
| Fenyvesi, T | 1 |
| Káldor, A | 1 |
| Sebestyén, K | 1 |
Trials
5 trials available for pindolol and Aging
| Article | Year |
|---|---|
The treatment of angina pectoris with the new beta-receptor blocker carteolol. Results of a controlled trial in comparison with pindolol.
Topics: Adult; Aging; Angina Pectoris; Carteolol; Clinical Trials as Topic; Electrocardiography; Female; Hum | 1983 |
Effects of age and smoking on the pharmacokinetics of pindolol and propranolol.
Topics: Adult; Aged; Aging; Female; Humans; Kinetics; Male; Middle Aged; Pindolol; Propranolol; Smoking; Tim | 1982 |
Aging effects on the organic base transporter and stereoselective renal clearance.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aging; Ammonium Chloride; Antimetabolites; Biological Tran | 1997 |
A multi-centre general practice trial of a pindolol/clopamide combination ('Viskaldix') in essential hypertension.
Topics: Adolescent; Adult; Aged; Aging; Blood Pressure; Clinical Trials as Topic; Clopamide; Drug Combinatio | 1979 |
[Effect of beta blockers with intrinsic sympathomimetic activity on blood pressure and blood lipids in patients with essential hypertension].
Topics: Aging; Blood Pressure; Clinical Trials as Topic; Exercise Test; Female; Heart Rate; Humans; Hyperten | 1989 |
Other Studies
53 other studies available for pindolol and Aging
| Article | Year |
|---|---|
Age-dependency of alpha- and beta-adrenoceptors on thrombocytes and lymphocytes of asthmatic and nonasthmatic children.
Topics: Adolescent; Adult; Aging; Albuterol; Asthma; Blood Platelets; Child; Child, Preschool; Humans; Infan | 1984 |
Influence of smoking and age on pharmacokinetics of beta-receptor blockers.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aging; Humans; Kinetics; Male; Middle Aged; Pindolol; Prop | 1982 |
Alterations in leukocyte beta-receptor affinity with aging. A potential explanation for altered beta-adrenergic sensitivity in the elderly.
Topics: Adrenergic beta-Agonists; Adult; Aged; Aging; Epinephrine; Humans; Isoproterenol; Leukocytes; Male; | 1984 |
Ontogeny of beta 1- and beta 2-adrenergic receptors in rat cerebellum and cerebral cortex.
Topics: Aging; Animals; Binding Sites; Binding, Competitive; Cerebellum; Cerebral Cortex; Female; Pindolol; | 1980 |
Beta-receptors during aging in respiratory tissues.
Topics: Aging; Animals; Benzyl Alcohols; Bronchi; Female; Guinea Pigs; Histamine; Isoproterenol; Muscle Rela | 1982 |
Ontogenesis of alpha- and beta-receptors located on cerebral microvessels.
Topics: Aging; Animals; Cerebral Cortex; Cerebrovascular Circulation; Kinetics; Pindolol; Rats; Receptors, A | 1982 |
Effect of age on beta-adrenergic receptors on cerebral microvessels.
Topics: Aging; Animals; Brain; Cyclic AMP; Male; Microcirculation; Norepinephrine; Pindolol; Rats; Rats, Inb | 1982 |
Endogenous and exogenous regulation of human alpha- and beta-adrenergic receptors.
Topics: Adolescent; Adult; Aged; Aging; Blood Platelets; Clonidine; Estrogens; Female; Guanosine Triphosphat | 1983 |
Postnatal exposure to the beta-adrenoceptor agonist clenbuterol has regionally selective direct and long-term effects on rat brain beta-adrenoceptors and monoamine metabolism.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Brain; Cerebellum; Clenbuterol; Do | 1993 |
Beta-adrenoceptor-G alpha S coupling decreases with age in rat aorta.
Topics: Aging; Animals; Aorta; GTP-Binding Proteins; Guanylyl Imidodiphosphate; In Vitro Techniques; Iodocya | 1995 |
Role of adrenergic tone in mechanical and functional properties of carotid artery during aging.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Aging; Animals; Carotid Arteries; Compliance | 1993 |
Effect of age on beta-receptors, Gs alpha- and Gi alpha- proteins in rat heart.
Topics: Adenylyl Cyclases; Aging; Amino Acid Sequence; Animals; Body Weight; GTP-Binding Proteins; Heart Ven | 1994 |
Age-related changes in beta-adrenergic neuroeffector systems in the human heart.
Topics: Adenylyl Cyclases; Adolescent; Adult; Aging; Binding, Competitive; Child; Child, Preschool; Denervat | 1994 |
Development and regulation of beta adrenergic receptors in kitten visual cortex: an immunocytochemical and autoradiographic study.
Topics: Aging; Animals; Animals, Newborn; Autoradiography; Cats; Geniculate Bodies; Immunohistochemistry; Io | 1993 |
Ontogeny of [125I]iodocyanopindolol-labelled 5-hydroxytryptamine1B-binding sites in the rat CNS.
Topics: Aging; Animals; Animals, Newborn; Binding Sites; Binding, Competitive; Central Nervous System; Indol | 1994 |
Effects of aging on AV nodal and ventricular beta-adrenergic receptors in the Fischer 344 rat.
Topics: Acetylcholinesterase; Aging; Animals; Atrioventricular Node; Binding, Competitive; Heart Ventricles; | 1994 |
3,5,3'-L-triiodothyronine regulation of beta-adrenergic receptor density and adenylyl cyclase activity in synaptosomal membranes of aged rats.
Topics: Adenylyl Cyclases; Aging; Alprostadil; Animals; Brain; Iodocyanopindolol; Male; Pindolol; Rats; Rats | 1993 |
Assessment of 8-OH-DPAT induced spontaneous tailflicks as an in vivo model of 5-HT1A function in young rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Animals, Newborn; Behavior, Animal; Dose-Res | 1993 |
Serotonin 1B receptors in the developing somatosensory and visual cortices are located on thalamocortical axons.
Topics: 5,7-Dihydroxytryptamine; Aging; Animals; Autoradiography; Axons; Cerebral Cortex; Iodine Radioisotop | 1993 |
Distribution of beta-adrenoceptor subtypes in gastrointestinal tract of nondiabetic and diabetic BB rats. A longitudinal study.
Topics: Adrenergic beta-Antagonists; Aging; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Typ | 1997 |
Adipose tissue beta-adrenergic and A1 adenosine receptors in suckling pigs.
Topics: Adipocytes; Adipose Tissue; Aging; Animals; Animals, Suckling; Body Weight; Female; Iodocyanopindolo | 1997 |
Pharmacological and molecular characterisation of beta-adrenoceptors in adult rat diaphragm muscle.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Dose-Respo | 1998 |
Beta-adrenergic receptor blocking drugs in spontaneous hypertension.
Topics: Adrenergic beta-Antagonists; Aging; Alprenolol; Animals; Blood Pressure; Hypertension; Male; Metopro | 1976 |
Age-related parallel decline in beta-adrenergic receptors, adenylate cyclase and phosphodiesterase activity in rat erythrocyte membranes.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Aging; Alprenolol; Animals; Benzyl Alcohols; | 1977 |
The effect of age on beta-adrenergic receptors and adenylate cyclase activity in rat erythrocytes.
Topics: Adenylyl Cyclases; Aging; Animals; Erythrocytes; In Vitro Techniques; Pindolol; Rats; Receptors, Adr | 1978 |
Influence of animal age on the beta-adrenergic system in cultured rat aortic and mesenteric artery smooth muscle cells.
Topics: Aging; Alprostadil; Animals; Aorta, Thoracic; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response | 1992 |
The effect of in vitro aging on human lung fibroblast beta-adrenergic receptor density, coupling and response.
Topics: Adenylyl Cyclases; Aging; Alprostadil; Cell Line; Cellular Senescence; Fibroblasts; Guanosine Tripho | 1992 |
Influence of exercise and age on myocardial beta-adrenergic receptor properties.
Topics: Aging; Analysis of Variance; Animals; Binding, Competitive; Female; Heart Rate; Iodocyanopindolol; I | 1992 |
Influence of age on the beta 1- and beta 2-adrenergic receptors in rat liver.
Topics: Adenylyl Cyclases; Aging; Animals; Binding, Competitive; Cell Membrane; Imidazoles; Liver; Liver Gly | 1992 |
Beta-adrenergic receptors and salivary gland secretion during aging.
Topics: Aging; Animals; Dose-Response Relationship, Drug; Female; Iodocyanopindolol; Isoproterenol; Pilocarp | 1992 |
Beta receptor density in human lymphocyte membranes: changing with aging?
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Aging; Binding Sites; Cell Membrane; Cy | 1991 |
Beta-adrenergic receptor activity of cerebral microvessels is reduced in aged rats.
Topics: Adenylyl Cyclases; Aging; Alkaline Phosphatase; Animals; Brain; Cerebrovascular Circulation; gamma-G | 1991 |
Steady state pharmacokinetics of hydrolysed bopindolol in young and elderly men.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Aging; Half-Life; Humans; H | 1991 |
Effect of age on the kinetics of the binding of iodocyanopindolol to a membrane preparation of rat lungs.
Topics: Aging; Animals; In Vitro Techniques; Iodocyanopindolol; Lung; Pindolol; Propranolol; Rats; Temperatu | 1991 |
Effect of age on upregulation of the cardiac adrenergic beta receptors.
Topics: Adrenergic beta-Antagonists; Aging; Animals; Heart; Hydroxydopamines; Iodine Radioisotopes; Male; My | 1990 |
Characterization of the beta-adrenergic transduction system in spleen mononuclear leukocyte membranes of young and senescent rats.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Aging; Animals; Binding, Competitive; Cell Membrane; | 1990 |
Ontogeny of renal beta adrenoceptors in the sheep.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Binding, Competitive; Ethanol | 1990 |
The beta-adrenergic transduction system in kidneys from young and senescent rats.
Topics: Adenylyl Cyclase Inhibitors; Aging; Animals; Cyclic AMP; Guanylyl Imidodiphosphate; In Vitro Techniq | 1990 |
Cardiac beta-adrenoceptor binding characteristics with age following adrenal demedullation.
Topics: Adrenal Medulla; Aging; Animals; Iodine Radioisotopes; Iodocyanopindolol; Kinetics; Male; Myocardium | 1990 |
The effects of ageing on prejunctional 5-hydroxytryptamine receptors in the rat vas deferens.
Topics: Aging; Animals; Electric Stimulation; In Vitro Techniques; Male; Muscle, Smooth; Myocardial Contract | 1990 |
Age-related decrease in beta adrenergic receptor-mediated vascular smooth muscle relaxation.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Acetylcholine; Aging; B | 1986 |
Adrenergic receptors in aging and Alzheimer's disease: increased beta 2-receptors in prefrontal cortex and hippocampus.
Topics: Aged; Aging; Alzheimer Disease; Autoradiography; Binding, Competitive; Cerebellum; Cerebral Cortex; | 1989 |
Effect of aging on properties and function of beta-adrenoceptors in rat lung.
Topics: Adenylyl Cyclases; Aging; Animals; Cyclic AMP; Iodocyanopindolol; Kinetics; Lung; Male; Membranes; P | 1989 |
Food restriction prevents an age-associated increase in rat liver beta-adrenergic receptors.
Topics: Adrenergic beta-Antagonists; Aging; Animals; Food Deprivation; Iodine Radioisotopes; Liver; Male; Pi | 1989 |
Beta-adrenergic receptors in DMBA-induced rat mammary tumors: correlation with progesterone receptor and tumor growth.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenergic beta-Antagonists; Aging; Animals; Catecholamines; Femal | 1989 |
Age-associated alterations in hepatic beta-adrenergic receptor/adenylate cyclase complex.
Topics: Adenylyl Cyclases; Aging; Animals; Binding, Competitive; Cell Separation; Enzyme Activation; Glycoge | 1987 |
Age-associated changes in pineal adrenergic receptors and melatonin synthesizing enzymes in the Wistar rat.
Topics: Acetylserotonin O-Methyltransferase; Aging; Animals; Arylamine N-Acetyltransferase; Binding, Competi | 1988 |
Development of beta 1 and beta 2 adrenergic receptors in baboon brain: an autoradiographic study using [125I]iodocyanopindolol.
Topics: Aging; Animals; Autoradiography; Brain; Female; Fetus; Iodine Radioisotopes; Iodocyanopindolol; Kine | 1988 |
Beta-blocking effect and pharmacokinetics of pindolol in young and elderly hypertensive patients.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aging; Creatinine; Exercise Test; Female; Half-Life; Heart | 1986 |
Comparison between the effects of aging on antagonist and agonist interactions with beta-adrenergic receptors on human mononuclear and polymorphonuclear leukocyte membranes.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Aging; Drug Interactions; Female | 1988 |
Age-related changes in the adrenergic control of glycogenolysis in rat liver: the significance of changes in receptor density.
Topics: Aging; Animals; Cell Membrane; Glucose; Iodine Radioisotopes; Iodocyanopindolol; Liver; Liver Glycog | 1985 |
Beta-adrenergic receptors, glucagon receptors, and their relationship to adenylate cyclase in rat liver during aging.
Topics: Adenylyl Cyclases; Aging; Animals; Colforsin; Enzyme Activation; Glucagon; Guanine Nucleotides; Guan | 1987 |
Heart rate after combined vagal and sympathetic blockade with atropine and different beta-receptor blocking agents.
Topics: Adrenergic beta-Antagonists; Adult; Aging; Atropine; Dose-Response Relationship, Drug; Electrocardio | 1973 |