Page last updated: 2024-11-02

pindolol and Aging

pindolol has been researched along with Aging in 58 studies

Pindolol: A moderately lipophilic beta blocker (ADRENERGIC BETA-ANTAGONISTS). It is non-cardioselective and has intrinsic sympathomimetic actions, but little membrane-stabilizing activity. (From Martindale, The Extra Pharmocopoeia, 30th ed, p638)
pindolol : A member of the class of indols which is the 2-hydroxy-3-(isopropylamino)propyl ether derivative of 1H-indol-4-ol.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"A large, open, multi-centre study was carried out in general practice to evaluate the effectiveness and tolerance of a combination of 10 mg pindolol plus 5 mg clopamide, in single tablet form, in the treatment of patients with essential hypertension."9.04A multi-centre general practice trial of a pindolol/clopamide combination ('Viskaldix') in essential hypertension. ( Cameron, EG; Crowder, D, 1979)
"A large, open, multi-centre study was carried out in general practice to evaluate the effectiveness and tolerance of a combination of 10 mg pindolol plus 5 mg clopamide, in single tablet form, in the treatment of patients with essential hypertension."5.04A multi-centre general practice trial of a pindolol/clopamide combination ('Viskaldix') in essential hypertension. ( Cameron, EG; Crowder, D, 1979)
"To determine the effect of aging on T3 up-regulation of beta-adrenergic receptor activity of purified synaptosomal membranes (SPM), beta-adrenergic receptor density (Bmax) and adenylyl cyclase (AC) activity were measured in young (6 months old) and aged (26 months old) male F-344 rats at baseline and after treatment with triiodothyronine (T3), 15 micrograms/100 g, intraperitoneally for 10 days."3.683,5,3'-L-triiodothyronine regulation of beta-adrenergic receptor density and adenylyl cyclase activity in synaptosomal membranes of aged rats. ( Mooradian, AD; Scarpace, PJ, 1993)
"The pharmacokinetics and beta-blocking effect of pindolol has been compared in 20 patients with essential hypertension (WHO Stage I), 10 below 25 years of age and 10 older than 60 years."3.67Beta-blocking effect and pharmacokinetics of pindolol in young and elderly hypertensive patients. ( Alván, G; Dunér, H; Garle, M; Gretzer, I; Sjöqvist, F, 1986)
" They were submitted to clinical exam, stress testing and plasma lipids dosage before and after four weeks of treatment."2.66[Effect of beta blockers with intrinsic sympathomimetic activity on blood pressure and blood lipids in patients with essential hypertension]. ( Bellotti, G; Braga, A; Pileggi, F; Santomauro, A; Serro-Azul, JB; Serro-Azul, LG; Wajngarten, M; Yazbek Júnior, P, 1989)
"1 Pharmacokinetic investigations were carried out in a group of 32 ambulant normal male volunteers in order to determine the effect of age and smoking on steady-state plasma levels of pindolol and propranolol."2.65Effects of age and smoking on the pharmacokinetics of pindolol and propranolol. ( Beveridge, T; Fitscha, P; Hitzenberger, G; Nüesch, E; Pacha, W, 1982)
"Steady-state pharmacokinetic parameters of the new, long-acting beta-adrenoceptor blocker bopindolol have been measured in 17 young and 20 elderly healthy men."1.28Steady state pharmacokinetics of hydrolysed bopindolol in young and elderly men. ( Holmes, D; Houle, JM; Nuesch, E; Rosenthaler, J, 1991)
" Although there was a statistically significant difference in certain pharmacokinetic parameters (maximum plasma concentration, area under the curve, elimination constant and elimination half-life) between elderly patients (more that 60 years) and young persons (20-30 years) no significant differences were found as far as smoking and nonsmoking is concerned."1.26Influence of smoking and age on pharmacokinetics of beta-receptor blockers. ( Beveridge, T; Fitscha, P; Hitzenberger, G; Nüesch, E; Pacha, W, 1982)
"Propranolol did not cause this pressor effect in prehypertensive (seven week old) SHRs."1.26Beta-adrenergic receptor blocking drugs in spontaneous hypertension. ( Levy, JV, 1976)

Research

Studies (58)

TimeframeStudies, this research(%)All Research%
pre-199028 (48.28)18.7374
1990's30 (51.72)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Reinhardt, D1
Zehmisch, T1
Becker, B1
Nagel-Hiemke, M1
Hitzenberger, G2
Fitscha, P2
Beveridge, T2
Nüesch, E3
Pacha, W2
Feldman, RD1
Limbird, LE1
Nadeau, J1
Robertson, D1
Wood, AJ1
Pittman, RN1
Minneman, KP1
Molinoff, PB1
Duncan, PG1
Brink, C1
Douglas, JS1
Kobayashi, H2
Cazzaniga, A1
Spano, P1
Trabucchi, M2
Maoret, T1
Spano, PF1
Brodde, OE1
Simon, H1
Schuppan, U1
Erdtsieck-Ernste, EB1
Feenstra, MG1
Botterblom, M1
Boer, GJ1
Gurdal, H1
Friedman, E1
Johnson, MD1
Benetos, A1
Huguet, F1
Albaladejo, P1
Brisac, AM1
Pappo, M1
Safar, ME1
Levy, BI1
Bazan, A1
Van de Velde, E5
Fraeyman, N6
White, M1
Roden, R1
Minobe, W1
Khan, MF1
Larrabee, P1
Wollmering, M1
Port, JD1
Anderson, F1
Campbell, D1
Feldman, AM1
Liu, Y1
Jia, W1
Strosberg, AD1
Cynader, M1
Pranzatelli, MR1
Galvan, I1
Kusumoto, FM1
Lurie, KG1
Dutton, J1
Capili, H1
Schwartz, JB1
Mooradian, AD2
Scarpace, PJ4
Kennedy, AT1
Kitchen, I1
Hill, RG1
Bennett-Clarke, CA1
Leslie, MJ1
Chiaia, NL1
Rhoades, RW1
Yu, O1
Ouyang, A1
Ujhelyi, MR1
Bottorff, MB1
Schur, M1
Roll, K1
Zhang, H1
Stewart, J1
Markel, ML1
Mersmann, HJ1
Carey, GB1
Smith, EO1
Collet, F1
Féve, B1
Frisdal, E1
Pavoine, C1
Pecker, F1
Atlan, G1
Levy, JV1
Bylund, DB1
Tellez-Iñon, MT1
Hollenberg, MD1
Bilezikian, JP1
Gammon, DE1
Crowder, D1
Cameron, EG1
Mader, SL1
Kilfeather, SA1
Collins, D1
McCormack, P1
Cotter, T1
O'Malley, K1
Lowenthal, DT1
Tümer, N3
Van Ermen, A1
Vanscheeuwijck, P5
Rajakumar, G1
Koller, MM1
Gietzen, DW1
Goodman, TA1
Weiler, PG1
Graf, K1
Fregeau, DR1
Magliozzi, JR1
Doran, AR1
Maddock, RJ1
Holmes, D1
Houle, JM1
Rosenthaler, J1
Houck, WT2
Roberts, J2
Felder, CC1
Piccio, MM1
McKelvey, AM1
Nakamura, KT1
Robillard, JE1
Jose, PA1
Boehm, C1
Borton, M1
Docherty, JR1
Tsujimoto, G1
Lee, CH1
Hoffman, BB1
Kalaria, RN1
Andorn, AC1
Tabaton, M1
Whitehouse, PJ1
Harik, SI1
Unnerstall, JR1
Dax, EM3
Ingram, DK1
Partilla, JS2
Gregerman, RI2
Marchetti, B1
Spinola, PG1
Plante, M1
Poyet, P1
Folléa, N1
Pelletier, G1
Labrie, F1
Serro-Azul, JB1
Wajngarten, M1
Santomauro, A1
Braga, A1
Yazbek Júnior, P1
Bellotti, G1
Serro-Azul, LG1
Pileggi, F1
Graham, SM1
Herring, PA1
Arinze, IJ1
Sugden, D1
Slesinger, PA1
Lowenstein, PR1
Singer, HS1
Walker, LC1
Casanova, MF1
Price, DL1
Coyle, JT1
Gretzer, I1
Alván, G1
Dunér, H1
Garle, M1
Sjöqvist, F1
Zahniser, NR1
Parker, DC1
Bier-Laning, CM1
Miller, JA1
Gerber, JG1
Nies, AS1
Bendeck, JL1
Noguchi, A1
Piñeyro, MA1
Fenyvesi, T1
Káldor, A1
Sebestyén, K1

Trials

5 trials available for pindolol and Aging

ArticleYear
The treatment of angina pectoris with the new beta-receptor blocker carteolol. Results of a controlled trial in comparison with pindolol.
    Arzneimittel-Forschung, 1983, Volume: 33, Issue:2a

    Topics: Adult; Aging; Angina Pectoris; Carteolol; Clinical Trials as Topic; Electrocardiography; Female; Hum

1983
Effects of age and smoking on the pharmacokinetics of pindolol and propranolol.
    British journal of clinical pharmacology, 1982, Volume: 13, Issue:Suppl 2

    Topics: Adult; Aged; Aging; Female; Humans; Kinetics; Male; Middle Aged; Pindolol; Propranolol; Smoking; Tim

1982
Aging effects on the organic base transporter and stereoselective renal clearance.
    Clinical pharmacology and therapeutics, 1997, Volume: 62, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aging; Ammonium Chloride; Antimetabolites; Biological Tran

1997
A multi-centre general practice trial of a pindolol/clopamide combination ('Viskaldix') in essential hypertension.
    Current medical research and opinion, 1979, Volume: 6, Issue:5

    Topics: Adolescent; Adult; Aged; Aging; Blood Pressure; Clinical Trials as Topic; Clopamide; Drug Combinatio

1979
[Effect of beta blockers with intrinsic sympathomimetic activity on blood pressure and blood lipids in patients with essential hypertension].
    Arquivos brasileiros de cardiologia, 1989, Volume: 53, Issue:6

    Topics: Aging; Blood Pressure; Clinical Trials as Topic; Exercise Test; Female; Heart Rate; Humans; Hyperten

1989

Other Studies

53 other studies available for pindolol and Aging

ArticleYear
Age-dependency of alpha- and beta-adrenoceptors on thrombocytes and lymphocytes of asthmatic and nonasthmatic children.
    European journal of pediatrics, 1984, Volume: 142, Issue:2

    Topics: Adolescent; Adult; Aging; Albuterol; Asthma; Blood Platelets; Child; Child, Preschool; Humans; Infan

1984
Influence of smoking and age on pharmacokinetics of beta-receptor blockers.
    Gerontology, 1982, Volume: 28 Suppl 1

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aging; Humans; Kinetics; Male; Middle Aged; Pindolol; Prop

1982
Alterations in leukocyte beta-receptor affinity with aging. A potential explanation for altered beta-adrenergic sensitivity in the elderly.
    The New England journal of medicine, 1984, Mar-29, Volume: 310, Issue:13

    Topics: Adrenergic beta-Agonists; Adult; Aged; Aging; Epinephrine; Humans; Isoproterenol; Leukocytes; Male;

1984
Ontogeny of beta 1- and beta 2-adrenergic receptors in rat cerebellum and cerebral cortex.
    Brain research, 1980, Apr-28, Volume: 188, Issue:2

    Topics: Aging; Animals; Binding Sites; Binding, Competitive; Cerebellum; Cerebral Cortex; Female; Pindolol;

1980
Beta-receptors during aging in respiratory tissues.
    European journal of pharmacology, 1982, Feb-19, Volume: 78, Issue:1

    Topics: Aging; Animals; Benzyl Alcohols; Bronchi; Female; Guinea Pigs; Histamine; Isoproterenol; Muscle Rela

1982
Ontogenesis of alpha- and beta-receptors located on cerebral microvessels.
    Brain research, 1982, Jun-24, Volume: 242, Issue:2

    Topics: Aging; Animals; Cerebral Cortex; Cerebrovascular Circulation; Kinetics; Pindolol; Rats; Receptors, A

1982
Effect of age on beta-adrenergic receptors on cerebral microvessels.
    Brain research, 1982, Jul-29, Volume: 244, Issue:2

    Topics: Aging; Animals; Brain; Cyclic AMP; Male; Microcirculation; Norepinephrine; Pindolol; Rats; Rats, Inb

1982
Endogenous and exogenous regulation of human alpha- and beta-adrenergic receptors.
    Journal of receptor research, 1983, Volume: 3, Issue:1-2

    Topics: Adolescent; Adult; Aged; Aging; Blood Platelets; Clonidine; Estrogens; Female; Guanosine Triphosphat

1983
Postnatal exposure to the beta-adrenoceptor agonist clenbuterol has regionally selective direct and long-term effects on rat brain beta-adrenoceptors and monoamine metabolism.
    Brain research. Developmental brain research, 1993, Jan-15, Volume: 71, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Brain; Cerebellum; Clenbuterol; Do

1993
Beta-adrenoceptor-G alpha S coupling decreases with age in rat aorta.
    Molecular pharmacology, 1995, Volume: 47, Issue:4

    Topics: Aging; Animals; Aorta; GTP-Binding Proteins; Guanylyl Imidodiphosphate; In Vitro Techniques; Iodocya

1995
Role of adrenergic tone in mechanical and functional properties of carotid artery during aging.
    The American journal of physiology, 1993, Volume: 265, Issue:4 Pt 2

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Aging; Animals; Carotid Arteries; Compliance

1993
Effect of age on beta-receptors, Gs alpha- and Gi alpha- proteins in rat heart.
    Biochemical pharmacology, 1994, Aug-03, Volume: 48, Issue:3

    Topics: Adenylyl Cyclases; Aging; Amino Acid Sequence; Animals; Body Weight; GTP-Binding Proteins; Heart Ven

1994
Age-related changes in beta-adrenergic neuroeffector systems in the human heart.
    Circulation, 1994, Volume: 90, Issue:3

    Topics: Adenylyl Cyclases; Adolescent; Adult; Aging; Binding, Competitive; Child; Child, Preschool; Denervat

1994
Development and regulation of beta adrenergic receptors in kitten visual cortex: an immunocytochemical and autoradiographic study.
    Brain research, 1993, Dec-31, Volume: 632, Issue:1-2

    Topics: Aging; Animals; Animals, Newborn; Autoradiography; Cats; Geniculate Bodies; Immunohistochemistry; Io

1993
Ontogeny of [125I]iodocyanopindolol-labelled 5-hydroxytryptamine1B-binding sites in the rat CNS.
    Neuroscience letters, 1994, Feb-14, Volume: 167, Issue:1-2

    Topics: Aging; Animals; Animals, Newborn; Binding Sites; Binding, Competitive; Central Nervous System; Indol

1994
Effects of aging on AV nodal and ventricular beta-adrenergic receptors in the Fischer 344 rat.
    The American journal of physiology, 1994, Volume: 266, Issue:4 Pt 2

    Topics: Acetylcholinesterase; Aging; Animals; Atrioventricular Node; Binding, Competitive; Heart Ventricles;

1994
3,5,3'-L-triiodothyronine regulation of beta-adrenergic receptor density and adenylyl cyclase activity in synaptosomal membranes of aged rats.
    Neuroscience letters, 1993, Oct-14, Volume: 161, Issue:1

    Topics: Adenylyl Cyclases; Aging; Alprostadil; Animals; Brain; Iodocyanopindolol; Male; Pindolol; Rats; Rats

1993
Assessment of 8-OH-DPAT induced spontaneous tailflicks as an in vivo model of 5-HT1A function in young rats.
    Neuropharmacology, 1993, Volume: 32, Issue:7

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Animals, Newborn; Behavior, Animal; Dose-Res

1993
Serotonin 1B receptors in the developing somatosensory and visual cortices are located on thalamocortical axons.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Jan-01, Volume: 90, Issue:1

    Topics: 5,7-Dihydroxytryptamine; Aging; Animals; Autoradiography; Axons; Cerebral Cortex; Iodine Radioisotop

1993
Distribution of beta-adrenoceptor subtypes in gastrointestinal tract of nondiabetic and diabetic BB rats. A longitudinal study.
    Digestive diseases and sciences, 1997, Volume: 42, Issue:6

    Topics: Adrenergic beta-Antagonists; Aging; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Typ

1997
Adipose tissue beta-adrenergic and A1 adenosine receptors in suckling pigs.
    Journal of animal science, 1997, Volume: 75, Issue:12

    Topics: Adipocytes; Adipose Tissue; Aging; Animals; Animals, Suckling; Body Weight; Female; Iodocyanopindolo

1997
Pharmacological and molecular characterisation of beta-adrenoceptors in adult rat diaphragm muscle.
    Respiration physiology, 1998, Volume: 112, Issue:1

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Dose-Respo

1998
Beta-adrenergic receptor blocking drugs in spontaneous hypertension.
    The American journal of medicine, 1976, Volume: 61, Issue:5

    Topics: Adrenergic beta-Antagonists; Aging; Alprenolol; Animals; Blood Pressure; Hypertension; Male; Metopro

1976
Age-related parallel decline in beta-adrenergic receptors, adenylate cyclase and phosphodiesterase activity in rat erythrocyte membranes.
    Life sciences, 1977, Aug-01, Volume: 21, Issue:3

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Aging; Alprenolol; Animals; Benzyl Alcohols;

1977
The effect of age on beta-adrenergic receptors and adenylate cyclase activity in rat erythrocytes.
    Life sciences, 1978, Jul-17, Volume: 23, Issue:3

    Topics: Adenylyl Cyclases; Aging; Animals; Erythrocytes; In Vitro Techniques; Pindolol; Rats; Receptors, Adr

1978
Influence of animal age on the beta-adrenergic system in cultured rat aortic and mesenteric artery smooth muscle cells.
    Journal of gerontology, 1992, Volume: 47, Issue:2

    Topics: Aging; Alprostadil; Animals; Aorta, Thoracic; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response

1992
The effect of in vitro aging on human lung fibroblast beta-adrenergic receptor density, coupling and response.
    Mechanisms of ageing and development, 1992, Volume: 63, Issue:3

    Topics: Adenylyl Cyclases; Aging; Alprostadil; Cell Line; Cellular Senescence; Fibroblasts; Guanosine Tripho

1992
Influence of exercise and age on myocardial beta-adrenergic receptor properties.
    Experimental gerontology, 1992, Volume: 27, Issue:2

    Topics: Aging; Analysis of Variance; Animals; Binding, Competitive; Female; Heart Rate; Iodocyanopindolol; I

1992
Influence of age on the beta 1- and beta 2-adrenergic receptors in rat liver.
    Molecular pharmacology, 1992, Volume: 42, Issue:4

    Topics: Adenylyl Cyclases; Aging; Animals; Binding, Competitive; Cell Membrane; Imidazoles; Liver; Liver Gly

1992
Beta-adrenergic receptors and salivary gland secretion during aging.
    Growth, development, and aging : GDA, 1992,Winter, Volume: 56, Issue:4

    Topics: Aging; Animals; Dose-Response Relationship, Drug; Female; Iodocyanopindolol; Isoproterenol; Pilocarp

1992
Beta receptor density in human lymphocyte membranes: changing with aging?
    Journal of gerontology, 1991, Volume: 46, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Aging; Binding Sites; Cell Membrane; Cy

1991
Beta-adrenergic receptor activity of cerebral microvessels is reduced in aged rats.
    Neurochemical research, 1991, Volume: 16, Issue:4

    Topics: Adenylyl Cyclases; Aging; Alkaline Phosphatase; Animals; Brain; Cerebrovascular Circulation; gamma-G

1991
Steady state pharmacokinetics of hydrolysed bopindolol in young and elderly men.
    European journal of clinical pharmacology, 1991, Volume: 41, Issue:2

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Aging; Half-Life; Humans; H

1991
Effect of age on the kinetics of the binding of iodocyanopindolol to a membrane preparation of rat lungs.
    Journal of receptor research, 1991, Volume: 11, Issue:6

    Topics: Aging; Animals; In Vitro Techniques; Iodocyanopindolol; Lung; Pindolol; Propranolol; Rats; Temperatu

1991
Effect of age on upregulation of the cardiac adrenergic beta receptors.
    Journal of gerontology, 1990, Volume: 45, Issue:2

    Topics: Adrenergic beta-Antagonists; Aging; Animals; Heart; Hydroxydopamines; Iodine Radioisotopes; Male; My

1990
Characterization of the beta-adrenergic transduction system in spleen mononuclear leukocyte membranes of young and senescent rats.
    Biochemical pharmacology, 1990, Jun-15, Volume: 39, Issue:12

    Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Aging; Animals; Binding, Competitive; Cell Membrane;

1990
Ontogeny of renal beta adrenoceptors in the sheep.
    Pediatric nephrology (Berlin, Germany), 1990, Volume: 4, Issue:6

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Binding, Competitive; Ethanol

1990
The beta-adrenergic transduction system in kidneys from young and senescent rats.
    European journal of pharmacology, 1990, Mar-13, Volume: 188, Issue:2-3

    Topics: Adenylyl Cyclase Inhibitors; Aging; Animals; Cyclic AMP; Guanylyl Imidodiphosphate; In Vitro Techniq

1990
Cardiac beta-adrenoceptor binding characteristics with age following adrenal demedullation.
    British journal of pharmacology, 1990, Volume: 99, Issue:1

    Topics: Adrenal Medulla; Aging; Animals; Iodine Radioisotopes; Iodocyanopindolol; Kinetics; Male; Myocardium

1990
The effects of ageing on prejunctional 5-hydroxytryptamine receptors in the rat vas deferens.
    Naunyn-Schmiedeberg's archives of pharmacology, 1990, Volume: 342, Issue:2

    Topics: Aging; Animals; Electric Stimulation; In Vitro Techniques; Male; Muscle, Smooth; Myocardial Contract

1990
Age-related decrease in beta adrenergic receptor-mediated vascular smooth muscle relaxation.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Acetylcholine; Aging; B

1986
Adrenergic receptors in aging and Alzheimer's disease: increased beta 2-receptors in prefrontal cortex and hippocampus.
    Journal of neurochemistry, 1989, Volume: 53, Issue:6

    Topics: Aged; Aging; Alzheimer Disease; Autoradiography; Binding, Competitive; Cerebellum; Cerebral Cortex;

1989
Effect of aging on properties and function of beta-adrenoceptors in rat lung.
    European journal of pharmacology, 1989, Oct-17, Volume: 172, Issue:4-5

    Topics: Adenylyl Cyclases; Aging; Animals; Cyclic AMP; Iodocyanopindolol; Kinetics; Lung; Male; Membranes; P

1989
Food restriction prevents an age-associated increase in rat liver beta-adrenergic receptors.
    Journal of gerontology, 1989, Volume: 44, Issue:3

    Topics: Adrenergic beta-Antagonists; Aging; Animals; Food Deprivation; Iodine Radioisotopes; Liver; Male; Pi

1989
Beta-adrenergic receptors in DMBA-induced rat mammary tumors: correlation with progesterone receptor and tumor growth.
    Breast cancer research and treatment, 1989, Volume: 13, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenergic beta-Antagonists; Aging; Animals; Catecholamines; Femal

1989
Age-associated alterations in hepatic beta-adrenergic receptor/adenylate cyclase complex.
    The American journal of physiology, 1987, Volume: 253, Issue:3 Pt 1

    Topics: Adenylyl Cyclases; Aging; Animals; Binding, Competitive; Cell Separation; Enzyme Activation; Glycoge

1987
Age-associated changes in pineal adrenergic receptors and melatonin synthesizing enzymes in the Wistar rat.
    Journal of neurochemistry, 1988, Volume: 50, Issue:2

    Topics: Acetylserotonin O-Methyltransferase; Aging; Animals; Arylamine N-Acetyltransferase; Binding, Competi

1988
Development of beta 1 and beta 2 adrenergic receptors in baboon brain: an autoradiographic study using [125I]iodocyanopindolol.
    The Journal of comparative neurology, 1988, Jul-15, Volume: 273, Issue:3

    Topics: Aging; Animals; Autoradiography; Brain; Female; Fetus; Iodine Radioisotopes; Iodocyanopindolol; Kine

1988
Beta-blocking effect and pharmacokinetics of pindolol in young and elderly hypertensive patients.
    European journal of clinical pharmacology, 1986, Volume: 31, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aging; Creatinine; Exercise Test; Female; Half-Life; Heart

1986
Comparison between the effects of aging on antagonist and agonist interactions with beta-adrenergic receptors on human mononuclear and polymorphonuclear leukocyte membranes.
    Journal of gerontology, 1988, Volume: 43, Issue:6

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Aging; Drug Interactions; Female

1988
Age-related changes in the adrenergic control of glycogenolysis in rat liver: the significance of changes in receptor density.
    Pediatric research, 1985, Volume: 19, Issue:8

    Topics: Aging; Animals; Cell Membrane; Glucose; Iodine Radioisotopes; Iodocyanopindolol; Liver; Liver Glycog

1985
Beta-adrenergic receptors, glucagon receptors, and their relationship to adenylate cyclase in rat liver during aging.
    Endocrinology, 1987, Volume: 120, Issue:4

    Topics: Adenylyl Cyclases; Aging; Animals; Colforsin; Enzyme Activation; Glucagon; Guanine Nucleotides; Guan

1987
Heart rate after combined vagal and sympathetic blockade with atropine and different beta-receptor blocking agents.
    International journal of clinical pharmacology, therapy and toxicology, 1973, Volume: 8, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Aging; Atropine; Dose-Response Relationship, Drug; Electrocardio

1973