pindolol has been researched along with Aggression in 14 studies
Pindolol: A moderately lipophilic beta blocker (ADRENERGIC BETA-ANTAGONISTS). It is non-cardioselective and has intrinsic sympathomimetic actions, but little membrane-stabilizing activity. (From Martindale, The Extra Pharmocopoeia, 30th ed, p638)
pindolol : A member of the class of indols which is the 2-hydroxy-3-(isopropylamino)propyl ether derivative of 1H-indol-4-ol.
Aggression: Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The hypothesis of this study was that central NE responsivity would predict aggression response to treatment with a NE medication, pindolol." | 5.11 | Noradrenergic activity is associated with response to pindolol in aggressive Alzheimer's disease patients. ( Eryavec, G; Herrmann, N; Khan, LR; Lanctôt, KL, 2004) |
| "Pindolol treatment was associated with significant therapeutic benefits without sedation and without the use-limiting side effects that occur with propranolol." | 2.66 | Therapeutic effects of pindolol on behavioral disturbances associated with organic brain disease: a double-blind study. ( Greendyke, RM; Kanter, DR, 1986) |
| " No change in fighting or Bmax was observed with the chronic administration of d-propranolol (5 mg/kg bid) or metoprolol (10 mg/kg bid)." | 1.27 | Increased shock-induced fighting with supersensitive beta-adrenergic receptors. ( Eichelman, B; Hegstrand, LR, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (28.57) | 18.7374 |
| 1990's | 5 (35.71) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nautiyal, KM | 1 |
| Tanaka, KF | 1 |
| Barr, MM | 1 |
| Tritschler, L | 1 |
| Le Dantec, Y | 1 |
| David, DJ | 1 |
| Gardier, AM | 1 |
| Blanco, C | 1 |
| Hen, R | 2 |
| Ahmari, SE | 1 |
| Fleminger, S | 2 |
| Greenwood, RJ | 2 |
| Oliver, DL | 2 |
| Herrmann, N | 1 |
| Lanctôt, KL | 1 |
| Eryavec, G | 1 |
| Khan, LR | 1 |
| Hegstrand, LR | 1 |
| Eichelman, B | 1 |
| Saudou, F | 1 |
| Amara, DA | 1 |
| Dierich, A | 1 |
| LeMeur, M | 1 |
| Ramboz, S | 1 |
| Segu, L | 1 |
| Buhot, MC | 1 |
| Sànchez, C | 1 |
| Hennig, J | 1 |
| Kroeger, A | 1 |
| Meyer, B | 1 |
| Prochaska, H | 1 |
| Krien, P | 1 |
| Huwe, S | 1 |
| Netter, P | 1 |
| Caspi, N | 1 |
| Modai, I | 1 |
| Barak, P | 1 |
| Waisbourd, A | 1 |
| Zbarsky, H | 1 |
| Hirschmann, S | 1 |
| Ritsner, M | 1 |
| Sijbesma, H | 1 |
| Schipper, J | 1 |
| De Kloet, ER | 1 |
| Coccaro, EF | 1 |
| Gabriel, S | 1 |
| Siever, LJ | 1 |
| von Hafften, AH | 1 |
| Jensen, CF | 1 |
| Eimer, M | 1 |
| Greendyke, RM | 1 |
| Kanter, DR | 1 |
3 reviews available for pindolol and Aggression
| Article | Year |
|---|---|
Pharmacological management for agitation and aggression in people with acquired brain injury.
Topics: Adrenergic beta-Antagonists; Aggression; Amantadine; Anxiety; Brain Injuries; Humans; Methylphenidat | 2003 |
Pharmacological management for agitation and aggression in people with acquired brain injury.
Topics: Adrenergic beta-Antagonists; Aggression; Amantadine; Anxiety; Brain Injuries; Humans; Methylphenidat | 2006 |
Management of the behavioral symptoms associated with dementia.
Topics: Aged; Aggression; Antipsychotic Agents; Dementia; Humans; Pindolol; Propranolol; Psychomotor Agitati | 1989 |
4 trials available for pindolol and Aggression
| Article | Year |
|---|---|
Noradrenergic activity is associated with response to pindolol in aggressive Alzheimer's disease patients.
Topics: Administration, Oral; Aged; Aged, 80 and over; Aggression; Alzheimer Disease; Behavioral Symptoms; C | 2004 |
Personality correlates of +/- pindolol induced decreases in prolactin.
Topics: Adrenergic beta-Antagonists; Adult; Aggression; Emotions; Humans; Impulsive Behavior; Male; Personal | 1998 |
Pindolol augmentation in aggressive schizophrenic patients: a double-blind crossover randomized study.
Topics: Administration, Oral; Adult; Aged; Aggression; Cross-Over Studies; Double-Blind Method; Humans; Male | 2001 |
Therapeutic effects of pindolol on behavioral disturbances associated with organic brain disease: a double-blind study.
Topics: Adult; Aged; Aggression; Clinical Trials as Topic; Double-Blind Method; Hospitalization; Humans; Imp | 1986 |
7 other studies available for pindolol and Aggression
| Article | Year |
|---|---|
Distinct Circuits Underlie the Effects of 5-HT1B Receptors on Aggression and Impulsivity.
Topics: Actins; Aggression; Animals; Animals, Newborn; Brain; Choice Behavior; Conditioning, Operant; Dopami | 2015 |
Increased shock-induced fighting with supersensitive beta-adrenergic receptors.
Topics: Aggression; Animals; Brain; Cell Membrane; Electroshock; Haloperidol; Humans; Male; Metoprolol; Pind | 1983 |
Enhanced aggressive behavior in mice lacking 5-HT1B receptor.
Topics: Aggression; Animals; Brain Chemistry; Chimera; Female; Indoles; Male; Mice; Motor Activity; Mutation | 1994 |
Interaction studies of 5-HT1A receptor antagonists and selective 5-HT reuptake inhibitors in isolated aggressive mice.
Topics: Adrenergic beta-Antagonists; Aggression; Animals; Drug Synergism; Male; Mice; Penbutolol; Pindolol; | 1997 |
The anti-aggressive drug eltoprazine preferentially binds to 5-HT1A and 5-HT1B receptor subtypes in rat brain: sensitivity to guanine nucleotides.
Topics: Aggression; Animals; Autoradiography; Brain; Brain Chemistry; Guanine Nucleotides; Guanosine Triphos | 1990 |
Buspirone challenge: preliminary evidence for a role for central 5-HT1a receptor function in impulsive aggressive behavior in humans.
Topics: Adult; Aggression; Buspirone; Female; Humans; Male; Metergoline; Personality Disorders; Pindolol; Pr | 1990 |
Paradoxical response to pindolol treatment for aggression in a patient with Huntington's disease.
Topics: Aggression; Drug Therapy, Combination; Humans; Huntington Disease; Male; Middle Aged; Pindolol; Thio | 1989 |