pinacidil has been researched along with Ventricular Dysfunction, Left in 2 studies
Pinacidil: A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed)
Ventricular Dysfunction, Left: A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The DFT, 90% action potential duration (APD(90)) and activation recovery interval (ARI) were evaluated before and after pinacidil administration (loading dosage 0." | 1.38 | The effect of pinacidil on postshock activation and ventricular defibrillation threshold in canine hearts. ( Gu, G; Jin, Q; Lin, CJ; Pang, Y; Shen, WF; Wu, LQ; Zhang, N; Zhou, J, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jin, Q | 1 |
| Zhang, N | 1 |
| Zhou, J | 1 |
| Lin, CJ | 1 |
| Pang, Y | 1 |
| Gu, G | 1 |
| Shen, WF | 1 |
| Wu, LQ | 1 |
| Lindhardt, TB | 1 |
| Gadsbøll, N | 1 |
| Kelbaek, H | 1 |
| Saunamäki, K | 1 |
| Madsen, JK | 1 |
| Clemmensen, P | 1 |
| Hesse, B | 1 |
| Haunsø, S | 1 |
1 trial available for pinacidil and Ventricular Dysfunction, Left
| Article | Year |
|---|---|
Pharmacological modulation of the ATP sensitive potassium channels during repeated coronary occlusions: no effect on myocardial ischaemia or function.
Topics: Adenosine Triphosphate; Angina Pectoris; Anti-Arrhythmia Agents; Balloon Occlusion; Coronary Stenosi | 2004 |
1 other study available for pinacidil and Ventricular Dysfunction, Left
| Article | Year |
|---|---|
The effect of pinacidil on postshock activation and ventricular defibrillation threshold in canine hearts.
Topics: Action Potentials; Animals; Differential Threshold; Disease Models, Animal; Dogs; Electric Countersh | 2012 |