pinacidil has been researched along with Tachyarrhythmia in 3 studies
Pinacidil: A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We compared antihypertensive effects of monotherapy with pinacidil (N = 197) or prazosin (N = 204) in a randomized, parallel, double-blind dose-titration study in which hydrochlorothiazide or propranolol could be added for adverse events or lack of efficacy." | 6.66 | Vasodilator monotherapy in the treatment of hypertension: comparative efficacy and safety of pinacidil, a potassium channel opener, and prazosin. ( Goldberg, MR; Rockhold, FW; Sushak, CS; Thompson, WL, 1988) |
| "We compared antihypertensive effects of monotherapy with pinacidil (N = 197) or prazosin (N = 204) in a randomized, parallel, double-blind dose-titration study in which hydrochlorothiazide or propranolol could be added for adverse events or lack of efficacy." | 2.66 | Vasodilator monotherapy in the treatment of hypertension: comparative efficacy and safety of pinacidil, a potassium channel opener, and prazosin. ( Goldberg, MR; Rockhold, FW; Sushak, CS; Thompson, WL, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zafalon, N | 1 |
| Oshiyama, NF | 1 |
| Bassani, JW | 1 |
| Bassani, RA | 1 |
| Smith, MP | 1 |
| Humphrey, SJ | 1 |
| Jackson, WF | 1 |
| Goldberg, MR | 1 |
| Sushak, CS | 1 |
| Rockhold, FW | 1 |
| Thompson, WL | 1 |
1 trial available for pinacidil and Tachyarrhythmia
| Article | Year |
|---|---|
Vasodilator monotherapy in the treatment of hypertension: comparative efficacy and safety of pinacidil, a potassium channel opener, and prazosin.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Data Interpretation, Statistical; Double-Blin | 1988 |
2 other studies available for pinacidil and Tachyarrhythmia
| Article | Year |
|---|---|
Muscarinic stimulation and pinacidil produce similar facilitation of tachyarrhythmia induction in rat isolated atria.
Topics: Action Potentials; Animals; Heart Atria; In Vitro Techniques; Male; Muscarinic Agonists; Pinacidil; | 2013 |
Selective in vivo antagonism of pinacidil-induced hypotension by the guanidine U37883A in anesthetized rats.
Topics: Adamantane; Anesthesia; Animals; Blood Pressure; Diuretics; Dose-Response Relationship, Drug; Female | 1994 |