pinacidil has been researched along with Pregnancy in 21 studies
Pinacidil: A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed)
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (33.33) | 18.2507 |
| 2000's | 5 (23.81) | 29.6817 |
| 2010's | 7 (33.33) | 24.3611 |
| 2020's | 2 (9.52) | 2.80 |
| Authors | Studies |
|---|---|
| Saha, PS | 3 |
| Knecht, TM | 3 |
| Arrick, DM | 3 |
| Watt, MJ | 3 |
| Scholl, JL | 3 |
| Mayhan, WG | 3 |
| Djokic, V | 1 |
| Jankovic, S | 1 |
| Labudovic-Borovic, M | 1 |
| Rakocevic, J | 1 |
| Stanisic, J | 1 |
| Rajkovic, J | 1 |
| Novakovic, R | 2 |
| Kostic, M | 1 |
| Djuric, M | 1 |
| Gostimirovic, M | 1 |
| Gojkovic-Bukarica, L | 1 |
| Li, H | 1 |
| Shin, SE | 1 |
| Seo, MS | 1 |
| An, JR | 1 |
| Ha, KS | 1 |
| Han, ET | 1 |
| Hong, SH | 1 |
| Kim, J | 1 |
| Yim, MJ | 1 |
| Lee, JM | 1 |
| An, TG | 1 |
| Jeon, J | 1 |
| Lee, SJ | 1 |
| Na, SH | 1 |
| Park, WS | 1 |
| Radunović, N | 1 |
| Marković-Lipkovski, J | 1 |
| Ćirović, S | 1 |
| Beleslin-Čokić, B | 1 |
| Ilić, B | 1 |
| Ivković, B | 1 |
| Heinle, H | 1 |
| Živanović, V | 1 |
| Gojković-Bukarica, LJ | 1 |
| Lovasz, N | 3 |
| Koncz, A | 1 |
| Domokos, D | 1 |
| Gaspar, R | 3 |
| Falkay, G | 3 |
| Williams, JL | 1 |
| Fyfe, GK | 1 |
| Sibley, CP | 1 |
| Baker, PN | 1 |
| Greenwood, SL | 1 |
| Greenwood, IA | 1 |
| Yeung, SY | 1 |
| Tribe, RM | 1 |
| Ohya, S | 1 |
| Sadlonova, V | 1 |
| Franova, S | 1 |
| Dokus, K | 1 |
| Janicek, F | 1 |
| Visnovsky, J | 1 |
| Sadlonova, J | 1 |
| Ducza, E | 2 |
| Baumbach, J | 1 |
| Shi, SQ | 1 |
| Shi, L | 1 |
| Balducci, J | 1 |
| Coonrod, DV | 1 |
| Garfield, RE | 2 |
| Longo, M | 1 |
| Jain, V | 1 |
| Vedernikov, YP | 1 |
| Hankins, GD | 1 |
| Saade, GR | 1 |
| Mandi, G | 1 |
| Sarkar, SN | 1 |
| Mishra, SK | 1 |
| Raviprakash, V | 1 |
| de Buys Roessingh, AS | 1 |
| de Lagausie, P | 1 |
| Barbet, JP | 1 |
| Mercier, JC | 1 |
| Aigrain, Y | 1 |
| Dinh-Xuan, AT | 1 |
| Morrison, JJ | 2 |
| Ashford, ML | 2 |
| Khan, RN | 2 |
| Smith, SK | 2 |
| Nelson, SH | 1 |
| Suresh, MS | 1 |
| Dehring, DJ | 1 |
| Johnson, RL | 1 |
| Pacher, P | 1 |
| Ungvári, Z | 1 |
| Nánási, PP | 1 |
| Mucha, I | 1 |
| Kecskeméti, V | 1 |
| Losonczy, G | 1 |
| Triggle, CR | 1 |
| Li, YQ | 1 |
| Wyse, DG | 1 |
| Chang, JK | 1 |
| Moore, P | 1 |
| Fineman, JR | 1 |
| Soifer, SJ | 1 |
| Heymann, MA | 1 |
| Piper, I | 1 |
| Minshall, E | 1 |
| Downing, SJ | 1 |
| Hollingsworth, M | 1 |
| Sadraei, H | 1 |
21 other studies available for pinacidil and Pregnancy
| Article | Year |
|---|---|
Prenatal exposure to alcohol impairs responses of cerebral arterioles to activation of potassium channels: Role of oxidative stress.
Topics: Adenosine Triphosphate; Animals; Arterioles; Ethanol; Female; Humans; Iloprost; Large-Conductance Ca | 2023 |
Prenatal exposure to alcohol impairs responses of cerebral arterioles to activation of potassium channels: Role of oxidative stress.
Topics: Adenosine Triphosphate; Animals; Arterioles; Ethanol; Female; Humans; Iloprost; Large-Conductance Ca | 2023 |
Prenatal exposure to alcohol impairs responses of cerebral arterioles to activation of potassium channels: Role of oxidative stress.
Topics: Adenosine Triphosphate; Animals; Arterioles; Ethanol; Female; Humans; Iloprost; Large-Conductance Ca | 2023 |
Prenatal exposure to alcohol impairs responses of cerebral arterioles to activation of potassium channels: Role of oxidative stress.
Topics: Adenosine Triphosphate; Animals; Arterioles; Ethanol; Female; Humans; Iloprost; Large-Conductance Ca | 2023 |
Pregnancy-induced hypertension decreases K
Topics: Adult; Antihypertensive Agents; Diabetes, Gestational; Female; Humans; Hypertension, Pregnancy-Induc | 2020 |
Alterations of ATP-sensitive K
Topics: Adenosine; Adenosine Triphosphate; Arteries; Colforsin; Cyclic AMP-Dependent Protein Kinases; Diabet | 2018 |
Effects of the polyphenol resveratrol on contractility of human term pregnant myometrium.
Topics: Female; Humans; In Vitro Techniques; Myometrium; Oxytocin; Pinacidil; Potassium Channels; Pregnancy; | 2015 |
ATP-sensitive potassium channels modulate in vitro tocolytic effects of β₂-adrenergic receptor agonists on uterine muscle rings in rats in early but not in late pregnancy.
Topics: Adrenergic beta-2 Receptor Agonists; Albuterol; Animals; Drug Synergism; Female; Glyburide; In Vitro | 2015 |
K+ channel inhibition modulates the biochemical and morphological differentiation of human placental cytotrophoblast cells in vitro.
Topics: 4-Aminopyridine; Arachidonic Acids; Barium Compounds; Calcium Channel Blockers; Cell Differentiation | 2008 |
Loss of functional K+ channels encoded by ether-à-go-go-related genes in mouse myometrium prior to labour onset.
Topics: 4-Aminopyridine; Animals; Chlorobenzenes; Cresols; Electric Stimulation; Electrophysiological Phenom | 2009 |
Participation of BKCa2+ and KATP potassium ion channels in the contractility of human term pregnant myometrium in in vitro conditions.
Topics: Benzimidazoles; Female; Humans; In Vitro Techniques; KATP Channels; Large-Conductance Calcium-Activa | 2011 |
Ontogeny of sulfonylurea-binding regulatory subunits of K(ATP) channels in the pregnant rat myometrium.
Topics: Animals; ATP-Binding Cassette Transporters; Diazoxide; Female; Gene Expression Regulation; In Vitro | 2011 |
[Ontogeny of sulphonylurea-binding regulatory subunits of K(ATP) channels in the pregnant rat myometrium].
Topics: Animals; ATP-Binding Cassette Transporters; Blotting, Western; Diazoxide; Female; Gene Expression Re | 2011 |
Inhibition of uterine contractility with various tocolytics with and without progesterone: in vitro studies.
Topics: Adult; Female; Humans; Indomethacin; Magnesium Sulfate; Myometrium; Nifedipine; Obstetric Labor, Pre | 2012 |
Effects of L-type Ca(2+)-channel blockade, K(+)(ATP)-channel opening and nitric oxide on human uterine contractility in relation to gestational age and labour.
Topics: Adult; Arginine; Calcium Channel Blockers; Calcium Channels, L-Type; Female; Gestational Age; Humans | 2003 |
Effects of calcium channel blocker, mibefradil, and potassium channel opener, pinacidil, on the contractile response of mid-pregnant goat myometrium.
Topics: Adenosine Triphosphate; Animals; Calcium Channel Blockers; Dose-Response Relationship, Drug; Female; | 2005 |
Role of ATP-dependent potassium channels in pulmonary vascular tone of fetal lambs with congenital diaphragmatic hernia.
Topics: Adenosine Triphosphate; Animals; Female; Glyburide; Hernia, Diaphragmatic; Hernias, Diaphragmatic, C | 2006 |
The effects of potassium channel openers on isolated pregnant human myometrium before and after the onset of labor: potential for tocolysis.
Topics: Benzopyrans; Cromakalim; Female; Guanidines; Humans; In Vitro Techniques; Labor Onset; Myometrium; O | 1993 |
Relaxation by calcitonin gene-related peptide may involve activation of K+ channels in the human uterine artery.
Topics: Adenosine Triphosphate; Adult; Arteries; Calcitonin Gene-Related Peptide; Female; Glyburide; Guanidi | 1993 |
Activation of large-conductance potassium channels in pregnant human myometrium by pinacidil.
Topics: Calcium; Charybdotoxin; Electric Conductivity; Female; Glyburide; Guanidines; Humans; Muscle Relaxat | 1998 |
Post-partum prolongation of the atrial repolarization in rabbit.
Topics: 4-Aminopyridine; Action Potentials; Animals; Atrial Function; Electrophysiology; Estrogens; Female; | 1999 |
Comparative effects of the K+ channel openers, pinacidil and cromakalim on vascular tone: sensitivity to glyburide and calcium.
Topics: Animals; Benzopyrans; Calcium; Cromakalim; Female; Glyburide; Guanidines; Humans; In Vitro Technique | 1992 |
K+ channel pulmonary vasodilation in fetal lambs: role of endothelium-derived nitric oxide.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Animals; Arginine; Blood Pressure; Female; Fe | 1992 |
Effects of several potassium channel openers and glibenclamide on the uterus of the rat.
Topics: Animals; Benzopyrans; Blood Pressure; Cromakalim; Female; Glyburide; Guanidines; Heart Rate; Hemodyn | 1990 |