pinacidil has been researched along with Paralysis, Hyperkalemic Periodic in 1 studies
Pinacidil: A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed)
Paralysis, Hyperkalemic Periodic: An autosomal dominant familial disorder which presents in infancy or childhood and is characterized by episodes of weakness associated with hyperkalemia. During attacks, muscles of the lower extremities are initially affected, followed by the lower trunk and arms. Episodes last from 15-60 minutes and typically occur after a period of rest following exercise. A defect in skeletal muscle sodium channels has been identified as the cause of this condition. Normokalemic periodic paralysis is a closely related disorder marked by a lack of alterations in potassium levels during attacks of weakness. (Adams et al., Principles of Neurology, 6th ed, p1481)
| Excerpt | Relevance | Reference |
|---|---|---|
| " In one study dichlorphenamide (DCP) vs placebo was tested in two groups of participants: 42 with hypokalemic periodic paralysis (HypoPP) and 31 with hyperkalemic periodic paralysis (HyperPP), based on clinical criteria." | 4.84 | Treatment for periodic paralysis. ( Links, TP; Meola, G; Panzeri, M; Rose, MR; Sansone, V, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sansone, V | 1 |
| Meola, G | 1 |
| Links, TP | 1 |
| Panzeri, M | 1 |
| Rose, MR | 1 |
1 review available for pinacidil and Paralysis, Hyperkalemic Periodic
| Article | Year |
|---|---|
Treatment for periodic paralysis.
Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Dichlorphenamide; Humans; Hypokalemic Periodic Paralys | 2008 |