pinacidil has been researched along with Obesity in 2 studies
Pinacidil: A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed)
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Obesity was induced by 24 weeks of high-fat diet feeding in male Sprague-Dawley rats." | 1.35 | Altered ATP-sensitive potassium channels may underscore obesity-triggered increase in blood pressure. ( Cao, YX; Fan, LH; Hu, Z; Huo, JH; Ma, AQ; Tian, HY, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fan, LH | 2 |
| Tian, HY | 2 |
| Ma, AQ | 2 |
| Hu, Z | 2 |
| Huo, JH | 2 |
| Cao, YX | 2 |
| Wang, J | 1 |
2 other studies available for pinacidil and Obesity
| Article | Year |
|---|---|
Altered ATP-sensitive potassium channels may underscore obesity-triggered increase in blood pressure.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Body Weight; Dietary Fats; Electr | 2008 |
Downregulation of Kir6.1/SUR2B channels in the obese rat aorta.
Topics: Animals; Aorta; ATP-Binding Cassette Transporters; Blood Pressure; Blotting, Western; Down-Regulatio | 2009 |