pinacidil has been researched along with Long QT Syndrome in 5 studies
Pinacidil: A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed)
Long QT Syndrome: A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Antazoline is a first-generation antihistamine with antiarrhythmic properties." | 1.48 | Antiarrhythmic effect of antazoline in experimental models of acquired short- and long-QT-syndromes. ( Dechering, DG; Eckardt, L; Ellermann, C; Fehr, M; Frommeyer, G; Kochhäuser, S; Sterneberg, M, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Limprasutr, V | 1 |
| Saengklub, N | 1 |
| Meedech, P | 1 |
| Kijtawornrat, A | 1 |
| Hamlin, RL | 1 |
| Ellermann, C | 1 |
| Sterneberg, M | 1 |
| Kochhäuser, S | 1 |
| Dechering, DG | 1 |
| Fehr, M | 1 |
| Eckardt, L | 1 |
| Frommeyer, G | 1 |
| Testai, L | 1 |
| Cecchetti, V | 1 |
| Sabatini, S | 1 |
| Martelli, A | 1 |
| Breschi, MC | 1 |
| Calderone, V | 1 |
| Drolet, B | 1 |
| Simard, C | 1 |
| Roden, DM | 1 |
| Carlsson, L | 1 |
| Abrahamsson, C | 1 |
| Drews, L | 1 |
| Duker, G | 1 |
5 other studies available for pinacidil and Long QT Syndrome
| Article | Year |
|---|---|
Characteristics of electromechanical window in anesthetized rabbit models of short QT and long QT syndromes.
Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Benzopyrans; Biomarkers; Biomarkers, Pharmacological; Cro | 2017 |
Antiarrhythmic effect of antazoline in experimental models of acquired short- and long-QT-syndromes.
Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Antazoline; Anti-Bacterial Agents; Arrhythm | 2018 |
Effects of K openers on the QT prolongation induced by HERG-blocking drugs in guinea-pigs.
Topics: Animals; Benzothiadiazines; Cromakalim; Decanoic Acids; Ether-A-Go-Go Potassium Channels; Glyburide; | 2010 |
Unusual effects of a QT-prolonging drug, arsenic trioxide, on cardiac potassium currents.
Topics: Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; CHO Cells; Cricetinae; Cricetulus; Gly | 2004 |
Antiarrhythmic effects of potassium channel openers in rhythm abnormalities related to delayed repolarization.
Topics: Animals; Anti-Arrhythmia Agents; Electrocardiography; Glyburide; Guanidines; Heart Conduction System | 1992 |