pinacidil has been researched along with Left Ventricular Hypertrophy in 3 studies
Pinacidil: A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Male Wistar rats after induction of myocardial infarction were randomized to either vehicle, agonists of K(ATP) channels nicorandil and pinacidil, an antagonist of K(ATP) channels glibenclamide, or a combination of nicorandil and glibenclamide or pinacidil and glibenclamide for 4 weeks." | 3.74 | Effect of ATP-sensitive potassium channel agonists on ventricular remodeling in healed rat infarcts. ( Chang, NC; Lee, TM; Lin, MS, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Park, WS | 1 |
| Hong, DH | 1 |
| Son, YK | 1 |
| Kim, MH | 1 |
| Jeong, SH | 1 |
| Kim, HK | 1 |
| Kim, N | 1 |
| Han, J | 1 |
| Lee, TM | 1 |
| Lin, MS | 1 |
| Chang, NC | 1 |
| Numaguchi, K | 1 |
| Egashira, K | 1 |
| Sakata, M | 1 |
| Shimokawa, H | 1 |
| Takeshita, A | 1 |
3 other studies available for pinacidil and Left Ventricular Hypertrophy
| Article | Year |
|---|---|
Alteration of ATP-sensitive K+ channels in rabbit aortic smooth muscle during left ventricular hypertrophy.
Topics: Animals; Aorta; Hypertrophy, Left Ventricular; KATP Channels; Male; Muscle, Smooth, Vascular; Organ | 2012 |
Effect of ATP-sensitive potassium channel agonists on ventricular remodeling in healed rat infarcts.
Topics: Animals; Glyburide; Hemodynamics; Hypertrophy, Left Ventricular; Immunohistochemistry; KATP Channels | 2008 |
Coronary vascular ATP-sensitive potassium channels are activated to a greater extent in spontaneously hypertensive rats than in Wistar-Kyoto rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Triphosphate; Animals; | 1996 |