Page last updated: 2024-11-02

pinacidil and Ischemia

pinacidil has been researched along with Ischemia in 4 studies

Pinacidil: A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed)

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
"The effect of repetitive stimulation, in the presence and absence of diltiazem or pinacidil, on the contractile responses of isolated strips of rabbit bladder detrusor to field stimulation and carbachol, after 2 hr of incubation in a medium that serves as an in vitro model of ischemia (oxygen and substrate depleted Tyrode's solution), was determined."7.70Effect of diltiazem and pinacidil on the response of the rabbit urinary bladder to repetitive stimulation and in vitro ischemia. ( Horan, P; Leggett, RE; Levin, RM; Whitbeck, C, 1999)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cortez-Toledo, E1
Rose, M1
Agu, E1
Dahlenburg, H1
Yao, W1
Nolta, JA1
Zhou, P1
Weselcouch, EO1
Sargent, C1
Wilde, MW1
Smith, MA1
Levin, RM2
Leggett, R1
Whitbeck, C2
Horan, P2
Leggett, RE1

Other Studies

4 other studies available for pinacidil and Ischemia

ArticleYear
Enhancing Retention of Human Bone Marrow Mesenchymal Stem Cells with Prosurvival Factors Promotes Angiogenesis in a Mouse Model of Limb Ischemia.
    Stem cells and development, 2019, 01-15, Volume: 28, Issue:2

    Topics: Amino Acid Chloromethyl Ketones; Animals; bcl-X Protein; Bone Marrow Cells; Bone Marrow Transplantat

2019
ATP-sensitive potassium channels and skeletal muscle function in vitro.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:1

    Topics: Animals; Benzopyrans; Cromakalim; Electric Stimulation; Energy Metabolism; Gallamine Triethiodide; G

1993
Correlation of EGTA and calcium-blocking agents on the response of the bladder to in vitro ischemia.
    Pharmacology, 1999, Volume: 58, Issue:3

    Topics: Animals; Calcium Channel Blockers; Carbachol; Chelating Agents; Diltiazem; Egtazic Acid; Electric St

1999
Effect of diltiazem and pinacidil on the response of the rabbit urinary bladder to repetitive stimulation and in vitro ischemia.
    Neurourology and urodynamics, 1999, Volume: 18, Issue:2

    Topics: Animals; Calcium Channel Blockers; Diltiazem; Electric Stimulation; In Vitro Techniques; Ischemia; M

1999