pinacidil has been researched along with Ischemia in 4 studies
Pinacidil: A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed)
Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of repetitive stimulation, in the presence and absence of diltiazem or pinacidil, on the contractile responses of isolated strips of rabbit bladder detrusor to field stimulation and carbachol, after 2 hr of incubation in a medium that serves as an in vitro model of ischemia (oxygen and substrate depleted Tyrode's solution), was determined." | 7.70 | Effect of diltiazem and pinacidil on the response of the rabbit urinary bladder to repetitive stimulation and in vitro ischemia. ( Horan, P; Leggett, RE; Levin, RM; Whitbeck, C, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cortez-Toledo, E | 1 |
| Rose, M | 1 |
| Agu, E | 1 |
| Dahlenburg, H | 1 |
| Yao, W | 1 |
| Nolta, JA | 1 |
| Zhou, P | 1 |
| Weselcouch, EO | 1 |
| Sargent, C | 1 |
| Wilde, MW | 1 |
| Smith, MA | 1 |
| Levin, RM | 2 |
| Leggett, R | 1 |
| Whitbeck, C | 2 |
| Horan, P | 2 |
| Leggett, RE | 1 |
4 other studies available for pinacidil and Ischemia
| Article | Year |
|---|---|
Enhancing Retention of Human Bone Marrow Mesenchymal Stem Cells with Prosurvival Factors Promotes Angiogenesis in a Mouse Model of Limb Ischemia.
Topics: Amino Acid Chloromethyl Ketones; Animals; bcl-X Protein; Bone Marrow Cells; Bone Marrow Transplantat | 2019 |
ATP-sensitive potassium channels and skeletal muscle function in vitro.
Topics: Animals; Benzopyrans; Cromakalim; Electric Stimulation; Energy Metabolism; Gallamine Triethiodide; G | 1993 |
Correlation of EGTA and calcium-blocking agents on the response of the bladder to in vitro ischemia.
Topics: Animals; Calcium Channel Blockers; Carbachol; Chelating Agents; Diltiazem; Egtazic Acid; Electric St | 1999 |
Effect of diltiazem and pinacidil on the response of the rabbit urinary bladder to repetitive stimulation and in vitro ischemia.
Topics: Animals; Calcium Channel Blockers; Diltiazem; Electric Stimulation; In Vitro Techniques; Ischemia; M | 1999 |