pinacidil has been researched along with Inflammation in 4 studies
Pinacidil: A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed)
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study aimed to determine the effect of pinacidil, a nonselective KATP channel opener, on diabetes-induced retinal gliosis and inflammation." | 4.02 | KATP Opener Attenuates Diabetic-Induced Müller Gliosis and Inflammation by Modulating Kir6.1 in Microglia. ( Chen, D; Chen, J; Li, H; Luo, C; Ma, JH; Sun, W; Tang, S; Xu, H, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Li, H | 1 |
| Chen, D | 1 |
| Sun, W | 1 |
| Chen, J | 2 |
| Luo, C | 1 |
| Xu, H | 1 |
| Ma, JH | 1 |
| Tang, S | 1 |
| Cao, S | 1 |
| Qin, Y | 1 |
| Shen, S | 1 |
| Ling, MY | 1 |
| Ma, ZY | 1 |
| Wang, YY | 1 |
| Qi, J | 1 |
| Liu, L | 1 |
| Li, L | 1 |
| Zhang, Y | 1 |
4 other studies available for pinacidil and Inflammation
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
KATP Opener Attenuates Diabetic-Induced Müller Gliosis and Inflammation by Modulating Kir6.1 in Microglia.
Topics: Animals; Cells, Cultured; Diabetes Mellitus, Experimental; DNA; Gene Expression Regulation; Gliosis; | 2021 |
Effects of pinacidil on changes to the microenvironment around the incision site, of a skin/muscle incision and retraction, in a rat model of postoperative pain.
Topics: Animals; Cellular Microenvironment; Dermatologic Surgical Procedures; Disease Models, Animal; Gene E | 2015 |
Up-regulated ATP-sensitive potassium channels play a role in increased inflammation and plaque vulnerability in macrophages.
Topics: Animals; Atherosclerosis; Cell Line; Glyburide; Inflammation; KATP Channels; Macrophages; Mice; Pina | 2013 |