pinacidil has been researched along with Hypotension in 3 studies
Pinacidil: A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed)
Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Eda, M | 1 |
| Takemoto, T | 1 |
| Ono, S | 1 |
| Okada, T | 1 |
| Kosaka, K | 1 |
| Gohda, M | 1 |
| Matzno, S | 1 |
| Nakamura, N | 1 |
| Fukaya, C | 1 |
| Smith, MP | 1 |
| Humphrey, SJ | 1 |
| Jackson, WF | 1 |
| Chen, SJ | 1 |
| Wu, CC | 1 |
| Yang, SN | 1 |
| Lin, CI | 1 |
| Yen, MH | 1 |
3 other studies available for pinacidil and Hypotension
| Article | Year |
|---|---|
Novel potassium-channel openers: preparation and pharmacological evaluation of racemic and optically active N-(6-amino-3-pyridyl)-N'-bicycloalkyl-N"-cyanoguanidine derivatives.
Topics: Animals; Antihypertensive Agents; Aorta; Blood Pressure; Bridged Bicyclo Compounds; Chromatography, | 1994 |
Selective in vivo antagonism of pinacidil-induced hypotension by the guanidine U37883A in anesthetized rats.
Topics: Adamantane; Anesthesia; Animals; Blood Pressure; Diuretics; Dose-Response Relationship, Drug; Female | 1994 |
Abnormal activation of K(+) channels in aortic smooth muscle of rats with endotoxic shock: electrophysiological and functional evidence.
Topics: Animals; Aorta; Apamin; Benzimidazoles; Charybdotoxin; Drug Interactions; Enzyme Inhibitors; Glyburi | 2000 |