pinacidil has been researched along with Hypertrophy in 2 studies
Pinacidil: A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed)
Hypertrophy: General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Normal rats as well as rats with bladder hypertrophy secondary to outflow obstruction were investigated cystometrically before and after administration of the potassium channel openers pinacidil or cromakalim one mg." | 3.67 | Effects of pinacidil and cromakalim (BRL 34915) on bladder function in rats with detrusor instability. ( Andersson, KE; Andersson, PO; Malmgren, A; Sjögren, C, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Malmgren, A | 2 |
| Andersson, KE | 2 |
| Andersson, PO | 2 |
| Fovaeus, M | 1 |
| Sjögren, C | 2 |
2 other studies available for pinacidil and Hypertrophy
| Article | Year |
|---|---|
Effects of cromakalim (BRL 34915) and pinacidil on normal and hypertrophied rat detrusor in vitro.
Topics: Animals; Benzopyrans; Carbachol; Cromakalim; Dose-Response Relationship, Drug; Electric Stimulation; | 1990 |
Effects of pinacidil and cromakalim (BRL 34915) on bladder function in rats with detrusor instability.
Topics: Animals; Benzopyrans; Cromakalim; Female; Guanidines; Hypertrophy; Pinacidil; Pyrroles; Rats; Rats, | 1989 |