pinacidil has been researched along with Hypertrophy, Left Ventricular in 3 studies
Pinacidil: A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed)
Hypertrophy, Left Ventricular: Enlargement of the LEFT VENTRICLE of the heart. This increase in ventricular mass is attributed to sustained abnormal pressure or volume loads and is a contributor to cardiovascular morbidity and mortality.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Male Wistar rats after induction of myocardial infarction were randomized to either vehicle, agonists of K(ATP) channels nicorandil and pinacidil, an antagonist of K(ATP) channels glibenclamide, or a combination of nicorandil and glibenclamide or pinacidil and glibenclamide for 4 weeks." | 3.74 | Effect of ATP-sensitive potassium channel agonists on ventricular remodeling in healed rat infarcts. ( Chang, NC; Lee, TM; Lin, MS, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Park, WS | 1 |
| Hong, DH | 1 |
| Son, YK | 1 |
| Kim, MH | 1 |
| Jeong, SH | 1 |
| Kim, HK | 1 |
| Kim, N | 1 |
| Han, J | 1 |
| Lee, TM | 1 |
| Lin, MS | 1 |
| Chang, NC | 1 |
| Numaguchi, K | 1 |
| Egashira, K | 1 |
| Sakata, M | 1 |
| Shimokawa, H | 1 |
| Takeshita, A | 1 |
3 other studies available for pinacidil and Hypertrophy, Left Ventricular
| Article | Year |
|---|---|
Alteration of ATP-sensitive K+ channels in rabbit aortic smooth muscle during left ventricular hypertrophy.
Topics: Animals; Aorta; Hypertrophy, Left Ventricular; KATP Channels; Male; Muscle, Smooth, Vascular; Organ | 2012 |
Effect of ATP-sensitive potassium channel agonists on ventricular remodeling in healed rat infarcts.
Topics: Animals; Glyburide; Hemodynamics; Hypertrophy, Left Ventricular; Immunohistochemistry; KATP Channels | 2008 |
Coronary vascular ATP-sensitive potassium channels are activated to a greater extent in spontaneously hypertensive rats than in Wistar-Kyoto rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Triphosphate; Animals; | 1996 |