pinacidil has been researched along with Hypertension, Renal in 2 studies
Pinacidil: A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed)
Hypertension, Renal: Persistent high BLOOD PRESSURE due to KIDNEY DISEASES, such as those involving the renal parenchyma, the renal vasculature, or tumors that secrete RENIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty patients with uncontrolled hypertension were treated with pinacidil for a mean period of 43 weeks (range 10-63 weeks)." | 7.67 | Treatment of essential hypertension and hypertension associated with renal impairment with pinacidil: a new vasodilator. ( Breen, EG; Keogh, JA; Mulhall, D, 1985) |
| "Twenty patients with uncontrolled hypertension were treated with pinacidil for a mean period of 43 weeks (range 10-63 weeks)." | 3.67 | Treatment of essential hypertension and hypertension associated with renal impairment with pinacidil: a new vasodilator. ( Breen, EG; Keogh, JA; Mulhall, D, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arrigoni-Martelli, E | 1 |
| Nielsen, CK | 1 |
| Olsen, UB | 1 |
| Petersen, HJ | 1 |
| Breen, EG | 1 |
| Mulhall, D | 1 |
| Keogh, JA | 1 |
2 other studies available for pinacidil and Hypertension, Renal
| Article | Year |
|---|---|
N''-cyano-N-4-pyridyl-N'-1,2,2-trimethylpropylguanidine, monohydrate (P 1134): a new, potent vasodilator.
Topics: Animals; Blood Pressure; Cardiac Output; Dogs; Dose-Response Relationship, Drug; Guanidines; Heart R | 1980 |
Treatment of essential hypertension and hypertension associated with renal impairment with pinacidil: a new vasodilator.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Female; Guanidines; Heart Rate; Humans; Hypert | 1985 |