pinacidil has been researched along with Hyperkalemia in 5 studies
Pinacidil: A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed)
Hyperkalemia: Abnormally high potassium concentration in the blood, most often due to defective renal excretion. It is characterized clinically by electrocardiographic abnormalities (elevated T waves and depressed P waves, and eventually by atrial asystole). In severe cases, weakness and flaccid paralysis may occur. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diazoxide did not increase sarcolemmal adenosine triphosphate-sensitive potassium current in wild-type myocytes, although they demonstrated significant swelling during exposure to cardioplegia that was prevented by diazoxide." | 1.36 | Diazoxide maintenance of myocyte volume and contractility during stress: evidence for a non-sarcolemmal K(ATP) channel location. ( Al-Dadah, AS; Lawton, JS; Maffit, SK; Nichols, CG; Schuessler, RB; Sellitto, AD; Zhang, H, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sellitto, AD | 1 |
| Maffit, SK | 1 |
| Al-Dadah, AS | 1 |
| Zhang, H | 1 |
| Schuessler, RB | 1 |
| Nichols, CG | 1 |
| Lawton, JS | 2 |
| Wang, J | 1 |
| Zhou, X | 1 |
| Zhao, Y | 1 |
| Tang, H | 1 |
| Hu, Y | 1 |
| Hsia, PW | 1 |
| McClain, LC | 1 |
| Maier, GW | 1 |
| Damiano, RJ | 1 |
| Tang, T | 1 |
| Dong, C | 1 |
| Duffield, R | 1 |
| Ho, AK | 1 |
| Yu, T | 1 |
| Yu, Z | 1 |
| Liu, X | 1 |
| Yang, S | 1 |
| Ye, Y | 1 |
5 other studies available for pinacidil and Hyperkalemia
| Article | Year |
|---|---|
Diazoxide maintenance of myocyte volume and contractility during stress: evidence for a non-sarcolemmal K(ATP) channel location.
Topics: Animals; ATP-Binding Cassette Transporters; Cardioplegic Solutions; Cardiotonic Agents; Cell Size; D | 2010 |
Myocardial protection of immature rabbits: polarizing versus depolarizing.
Topics: Aging; Animals; Bicarbonates; Body Water; Calcium Chloride; Cardiotonic Agents; Coronary Circulation | 2003 |
Myocardial oxygen consumption in the rabbit heart after ischemia: hyperpolarized arrest with pinacidil versus depolarized hyperkalemic arrest.
Topics: Animals; Coronary Circulation; Diastole; Female; Guanidines; Heart Arrest, Induced; Hyperkalemia; Ma | 1997 |
Protection of cardiomyocytes by pinacidil during metabolic inhibition and hyperkalemia.
Topics: Adenosine Triphosphate; Animals; Bepridil; Calcium; Calcium Channel Blockers; Cells, Cultured; Chick | 1999 |
Myocardial protection with pinacidil induced hyperpolarized arrest during cardiopulmonary bypass.
Topics: Adenine Nucleotides; Alkaline Phosphatase; Animals; Antihypertensive Agents; Cardiopulmonary Bypass; | 2001 |