pinacidil has been researched along with Hyperemia in 3 studies
Pinacidil: A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed)
Hyperemia: The presence of an increased amount of blood in a body part or an organ leading to congestion or engorgement of blood vessels. Hyperemia can be due to increase of blood flow into the area (active or arterial), or due to obstruction of outflow of blood from the area (passive or venous).
| Excerpt | Relevance | Reference |
|---|---|---|
| " We tested the hypothesis that pinacidil, a selective agonist for the SUR2B receptor found on smooth muscles, could serve as an independent means of inducing vasodilation and increased local blood volume to emulate functional hyperemia." | 7.75 | Pinacidil induces vascular dilation and hyperemia in vivo and does not impact biophysical properties of neurons and astrocytes in vitro. ( Brumberg, JC; Cao, R; Cardin, J; Higashikubo, BT; Knoblich, U; Moore, CI; Nelson, MT; Ramos, R, 2009) |
| " We tested the hypothesis that pinacidil, a selective agonist for the SUR2B receptor found on smooth muscles, could serve as an independent means of inducing vasodilation and increased local blood volume to emulate functional hyperemia." | 3.75 | Pinacidil induces vascular dilation and hyperemia in vivo and does not impact biophysical properties of neurons and astrocytes in vitro. ( Brumberg, JC; Cao, R; Cardin, J; Higashikubo, BT; Knoblich, U; Moore, CI; Nelson, MT; Ramos, R, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cao, R | 1 |
| Higashikubo, BT | 1 |
| Cardin, J | 1 |
| Knoblich, U | 1 |
| Ramos, R | 1 |
| Nelson, MT | 1 |
| Moore, CI | 1 |
| Brumberg, JC | 1 |
| Wang, SY | 1 |
| Friedman, M | 1 |
| Johnson, RG | 1 |
| Zeind, AJ | 1 |
| Sellke, FW | 1 |
| Duncker, DJ | 1 |
| van Zon, NS | 1 |
| Pavek, TJ | 1 |
| Herrlinger, SK | 1 |
| Bache, RJ | 1 |
3 other studies available for pinacidil and Hyperemia
| Article | Year |
|---|---|
Pinacidil induces vascular dilation and hyperemia in vivo and does not impact biophysical properties of neurons and astrocytes in vitro.
Topics: Animals; Astrocytes; Cell Culture Techniques; Hyperemia; Mice; Mice, Inbred C57BL; Neocortex; Neuron | 2009 |
Adenosine triphosphate-sensitive K+ channels mediate postcardioplegia coronary hyperemia.
Topics: Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Vessels; Glyburide; Guanidines; Hear | 1995 |
Endogenous adenosine mediates coronary vasodilation during exercise after K(ATP)+ channel blockade.
Topics: Adenosine; Animals; Coronary Circulation; Diastole; Dogs; Glyburide; Guanidines; Hemodynamics; Hyper | 1995 |