pinacidil has been researched along with Hypercapnia in 3 studies
Pinacidil: A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed)
Hypercapnia: A clinical manifestation of abnormal increase in the amount of carbon dioxide in arterial blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Posthypothermic rapid rewarming caused cerebral vascular abnormalities, including a diminished response to acetylcholine, hypercapnia, pinacidil, and SNP." | 3.72 | Uncomplicated rapid posthypothermic rewarming alters cerebrovascular responsiveness. ( Kontos, HA; Povlishock, JT; Suehiro, E; Ueda, Y; Wei, EP, 2004) |
| " The aims of this study were to compare in the rat isolated perfused lung preparation, the dilator actions of nicorandil, pinacidil and nitroglycerin on the hypoxic pulmonary pressure response with or without hypercapnic acidosis and to investigate the possible involvement of K channels and EDRF in these effects." | 3.69 | Comparison of the effects of nicorandil, pinacidil and nitroglycerin on hypoxic and hypercapnic pulmonary vasoconstriction in the isolated perfused lung of rat. ( Advenier, C; Dumas, JP; Dumas, M; Giudicelli, JF; Rochette, L, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ueda, Y | 1 |
| Suehiro, E | 1 |
| Wei, EP | 2 |
| Kontos, HA | 2 |
| Povlishock, JT | 1 |
| Dumas, M | 1 |
| Dumas, JP | 1 |
| Rochette, L | 1 |
| Advenier, C | 1 |
| Giudicelli, JF | 1 |
| Rosenblum, WI | 1 |
3 other studies available for pinacidil and Hypercapnia
| Article | Year |
|---|---|
Uncomplicated rapid posthypothermic rewarming alters cerebrovascular responsiveness.
Topics: Acetylcholine; Animals; Carbon Dioxide; Cerebrovascular Circulation; Disease Models, Animal; Hyperca | 2004 |
Comparison of the effects of nicorandil, pinacidil and nitroglycerin on hypoxic and hypercapnic pulmonary vasoconstriction in the isolated perfused lung of rat.
Topics: Acidosis; Animals; Guanidines; Hypercapnia; Hypoxia; In Vitro Techniques; Lung; Male; Niacinamide; N | 1996 |
Evidence for a K(ATP) ion channel link in the inhibition of hypercapnic dilation of pial arterioles by 7-nitroindazole and tetrodotoxin.
Topics: Animals; Arginine; Arterioles; Carbon Dioxide; Cromakalim; Hypercapnia; Indazoles; Ion Channel Gatin | 2001 |