pinacidil has been researched along with Diabetes Mellitus, Type 1 in 1 studies
Pinacidil: A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed)
Diabetes Mellitus, Type 1: A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
| Excerpt | Relevance | Reference |
|---|---|---|
| "IDDM was induced in rats by streptozotocin (STZ) injection, and adequate insulin was provided to maintain moderate hyperglycemia." | 1.31 | Exaggerated impact of ATP-sensitive K(+) channels on afferent arteriolar diameter in diabetes mellitus. ( Bast, JP; Carmines, PK; Fallet, RW; Ikenaga, H, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ikenaga, H | 1 |
| Bast, JP | 1 |
| Fallet, RW | 1 |
| Carmines, PK | 1 |
1 other study available for pinacidil and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Exaggerated impact of ATP-sensitive K(+) channels on afferent arteriolar diameter in diabetes mellitus.
Topics: Adenosine Triphosphate; Animals; Arterioles; Benzopyrans; Cyclopentanes; Diabetes Mellitus, Experime | 2000 |