pinacidil has been researched along with Cardiac Remodeling, Ventricular in 3 studies
Pinacidil: A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We assessed whether pravastatin attenuates cardiac sympathetic reinnervation after myocardial infarction through the activation of ATP-sensitive K(+) (K(ATP)) channels." | 3.74 | Effect of pravastatin on sympathetic reinnervation in postinfarcted rats. ( Chang, NC; Lee, TM; Lin, MS, 2007) |
| "Male Wistar rats after induction of myocardial infarction were randomized to either vehicle, agonists of K(ATP) channels nicorandil and pinacidil, an antagonist of K(ATP) channels glibenclamide, or a combination of nicorandil and glibenclamide or pinacidil and glibenclamide for 4 weeks." | 3.74 | Effect of ATP-sensitive potassium channel agonists on ventricular remodeling in healed rat infarcts. ( Chang, NC; Lee, TM; Lin, MS, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, TM | 2 |
| Lin, MS | 2 |
| Chang, NC | 2 |
| Wang, H | 1 |
1 review available for pinacidil and Cardiac Remodeling, Ventricular
| Article | Year |
|---|---|
Cardiovascular ATP-sensitive K+ channel as a new molecular target for development of antihypertensive drugs.
Topics: Adenosine Triphosphate; Animals; Antihypertensive Agents; Humans; Hypertension; Pinacidil; Potassium | 1998 |
2 other studies available for pinacidil and Cardiac Remodeling, Ventricular
| Article | Year |
|---|---|
Effect of pravastatin on sympathetic reinnervation in postinfarcted rats.
Topics: Animals; Blotting, Western; Cardiac Pacing, Artificial; Coronary Vessels; Disease Models, Animal; GA | 2007 |
Effect of ATP-sensitive potassium channel agonists on ventricular remodeling in healed rat infarcts.
Topics: Animals; Glyburide; Hemodynamics; Hypertrophy, Left Ventricular; Immunohistochemistry; KATP Channels | 2008 |