pinacidil has been researched along with Cardiac Failure in 4 studies
Pinacidil: A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Glibenclamide (10 μM) terminated these arrhythmias and restored APDs to control values." | 1.37 | Effects of KATP channel openers diazoxide and pinacidil in coronary-perfused atria and ventricles from failing and non-failing human hearts. ( Ambrosi, CM; Chang, R; Efimov, IR; Fedorov, VV; Glukhov, AV; Janks, D; Kostecki, G; Moazami, N; Nichols, CG; Schuessler, RB, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brennan, S | 1 |
| Jackson, R | 1 |
| Patel, M | 1 |
| Sims, MW | 1 |
| Hudman, D | 1 |
| Norman, RI | 1 |
| Lodwick, D | 1 |
| Rainbow, RD | 1 |
| Fedorov, VV | 1 |
| Glukhov, AV | 1 |
| Ambrosi, CM | 1 |
| Kostecki, G | 1 |
| Chang, R | 1 |
| Janks, D | 1 |
| Schuessler, RB | 1 |
| Moazami, N | 1 |
| Nichols, CG | 1 |
| Efimov, IR | 1 |
| Traverse, JH | 1 |
| Chen, Y | 1 |
| Hou, M | 1 |
| Li, Y | 1 |
| Bache, RJ | 1 |
| Satoh, K | 1 |
1 review available for pinacidil and Cardiac Failure
| Article | Year |
|---|---|
[Ca-antagonist, K-channel-opener in the treatment of patients with congestive heart failure].
Topics: Animals; Benzopyrans; Calcium Channel Blockers; Cromakalim; Guanidines; Heart Failure; Hemodynamics; | 1993 |
3 other studies available for pinacidil and Cardiac Failure
| Article | Year |
|---|---|
Early opening of sarcolemmal ATP-sensitive potassium channels is not a key step in PKC-mediated cardioprotection.
Topics: Action Potentials; Adenosine; Animals; Cardiotonic Agents; Cell Separation; Diazoxide; Enzyme Activa | 2015 |
Effects of KATP channel openers diazoxide and pinacidil in coronary-perfused atria and ventricles from failing and non-failing human hearts.
Topics: Action Potentials; Adolescent; Adult; Arrhythmias, Cardiac; Coronary Vessels; Diazoxide; Female; Gen | 2011 |
Effect of K+ATP channel and adenosine receptor blockade during rest and exercise in congestive heart failure.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Blood Flow Velocity; Cardiac Pacing, Artifi | 2007 |