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pinacidil and Asthma

pinacidil has been researched along with Asthma in 2 studies

Pinacidil: A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed)

Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).

Research Excerpts

ExcerptRelevanceReference
"The anti-allergic and anti-asthmatic activities of three potassium (K+) channel openers, cromakalim, pinacidil, and nicorandil, were investigated."7.68Effect of three novel K+ channel openers, cromakalim, pinacidil and nicorandil on allergic reaction and experimental asthma. ( Goto, S; Kitagaki, K; Koda, A; Nagai, H; Suda, H, 1991)
"Pinacidil is a new antihypertensive, direct vasodilator drug which has been classified as a K+ channel opener."5.27Effects of pinacidil on guinea-pig airway smooth muscle contracted by asthma mediators. ( Mellemkjaer, S; Nielsen, CB; Nielsen-Kudsk, JE; Siggaard, C, 1988)
"The anti-allergic and anti-asthmatic activities of three potassium (K+) channel openers, cromakalim, pinacidil, and nicorandil, were investigated."3.68Effect of three novel K+ channel openers, cromakalim, pinacidil and nicorandil on allergic reaction and experimental asthma. ( Goto, S; Kitagaki, K; Koda, A; Nagai, H; Suda, H, 1991)
"Pinacidil is a new antihypertensive, direct vasodilator drug which has been classified as a K+ channel opener."1.27Effects of pinacidil on guinea-pig airway smooth muscle contracted by asthma mediators. ( Mellemkjaer, S; Nielsen, CB; Nielsen-Kudsk, JE; Siggaard, C, 1988)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nagai, H1
Kitagaki, K1
Goto, S1
Suda, H1
Koda, A1
Nielsen-Kudsk, JE1
Mellemkjaer, S1
Siggaard, C1
Nielsen, CB1

Other Studies

2 other studies available for pinacidil and Asthma

ArticleYear
Effect of three novel K+ channel openers, cromakalim, pinacidil and nicorandil on allergic reaction and experimental asthma.
    Japanese journal of pharmacology, 1991, Volume: 56, Issue:1

    Topics: Airway Resistance; Animals; Asthma; Benzopyrans; Bronchodilator Agents; Cromakalim; Guanidines; Guin

1991
Effects of pinacidil on guinea-pig airway smooth muscle contracted by asthma mediators.
    European journal of pharmacology, 1988, Nov-22, Volume: 157, Issue:2-3

    Topics: Animals; Antihypertensive Agents; Asthma; Female; Guanidines; Guinea Pigs; Male; Muscle Contraction;

1988