pinacidil and Asthma
pinacidil has been researched along with Asthma in 2 studies
Pinacidil: A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed)
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "The anti-allergic and anti-asthmatic activities of three potassium (K+) channel openers, cromakalim, pinacidil, and nicorandil, were investigated." | 7.68 | Effect of three novel K+ channel openers, cromakalim, pinacidil and nicorandil on allergic reaction and experimental asthma. ( Goto, S; Kitagaki, K; Koda, A; Nagai, H; Suda, H, 1991) |
| "Pinacidil is a new antihypertensive, direct vasodilator drug which has been classified as a K+ channel opener." | 5.27 | Effects of pinacidil on guinea-pig airway smooth muscle contracted by asthma mediators. ( Mellemkjaer, S; Nielsen, CB; Nielsen-Kudsk, JE; Siggaard, C, 1988) |
| "The anti-allergic and anti-asthmatic activities of three potassium (K+) channel openers, cromakalim, pinacidil, and nicorandil, were investigated." | 3.68 | Effect of three novel K+ channel openers, cromakalim, pinacidil and nicorandil on allergic reaction and experimental asthma. ( Goto, S; Kitagaki, K; Koda, A; Nagai, H; Suda, H, 1991) |
| "Pinacidil is a new antihypertensive, direct vasodilator drug which has been classified as a K+ channel opener." | 1.27 | Effects of pinacidil on guinea-pig airway smooth muscle contracted by asthma mediators. ( Mellemkjaer, S; Nielsen, CB; Nielsen-Kudsk, JE; Siggaard, C, 1988) |
Research
Studies (2)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Nagai, H | 1 |
| Kitagaki, K | 1 |
| Goto, S | 1 |
| Suda, H | 1 |
| Koda, A | 1 |
| Nielsen-Kudsk, JE | 1 |
| Mellemkjaer, S | 1 |
| Siggaard, C | 1 |
| Nielsen, CB | 1 |
Other Studies
2 other studies available for pinacidil and Asthma
| Article | Year |
|---|---|
Effect of three novel K+ channel openers, cromakalim, pinacidil and nicorandil on allergic reaction and experimental asthma.
Topics: Airway Resistance; Animals; Asthma; Benzopyrans; Bronchodilator Agents; Cromakalim; Guanidines; Guin | 1991 |
Effects of pinacidil on guinea-pig airway smooth muscle contracted by asthma mediators.
Topics: Animals; Antihypertensive Agents; Asthma; Female; Guanidines; Guinea Pigs; Male; Muscle Contraction; | 1988 |