pinacidil has been researched along with Adenoma, beta-Cell in 4 studies
Pinacidil: A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The treatment with diazoxide or infection of ORP150 antisense adenovirus suppressed ORP150 expression, and glucose-stimulated insulin secretion was effectively prevented." | 1.33 | 150-kD oxygen-regulated protein is an essential factor for insulin release. ( Kobayashi, T; Ohta, Y, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kobayashi, T | 1 |
| Ohta, Y | 1 |
| Hoffman, FJ | 1 |
| Lenfers, JB | 1 |
| Niemers, E | 1 |
| Pleiss, U | 1 |
| Scriabine, A | 1 |
| Janis, RA | 1 |
| Chapman, JC | 1 |
| McClenaghan, NH | 1 |
| Cosgrove, KE | 1 |
| Hashmi, MN | 1 |
| Shepherd, RM | 1 |
| Giesberts, AN | 1 |
| White, SJ | 1 |
| Ammälä, C | 1 |
| Flatt, PR | 1 |
| Dunne, MJ | 2 |
4 other studies available for pinacidil and Adenoma, beta-Cell
| Article | Year |
|---|---|
150-kD oxygen-regulated protein is an essential factor for insulin release.
Topics: Adenoviridae; Animals; Antisense Elements (Genetics); Cell Line, Tumor; Cromakalim; Diazoxide; Genes | 2005 |
High affinity binding of a potassium channel agonist to intact rat insulinoma cells.
Topics: Animals; Aorta; Binding Sites; Binding, Competitive; Glyburide; Guanidines; Insulinoma; Kinetics; Ma | 1993 |
ATP-sensitive potassium channels and efaroxan-induced insulin release in the electrofusion-derived BRIN-BD11 beta-cell line.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Benzofurans; C | 1999 |
Effects of pinacidil, RP 49356 and nicorandil on ATP-sensitive potassium channels in insulin-secreting cells.
Topics: Adenoma, Islet Cell; Adenosine Triphosphate; Diazoxide; Glucose; Guanidines; Humans; Insulin; Insuli | 1990 |