Page last updated: 2024-08-22

pimozide and Electrocardiogram QT Prolonged

pimozide has been researched along with Electrocardiogram QT Prolonged in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's5 (55.56)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, XL; Kang, J; Kongsamut, S; Rampe, D; Roehr, J1
Cavalli, A; De Ponti, F; Poluzzi, E; Recanatini, M1
Pearlstein, R; Rampe, D; Vaz, R1
Calì, PV; Di Pino, A; Gulisano, M; Rizzo, R1
Bhattaram, A; Gobburu, J; Laughren, TP; Mathis, M; Pacanowski, M; Rogers, HL; Zineh, I1
Preskorn, SH1
Abe, J; Hamada, Y; Harada, T; Hashimoto, K; Horii, I; Sawada, Y; Shiotani, M1
Cardinal, R; Daleau, P; Drolet, B; Rousseau, G; Simard, C; Turgeon, J1
Bernstein, M1

Reviews

1 review(s) available for pimozide and Electrocardiogram QT Prolonged

ArticleYear
Understanding the structure-activity relationship of the human ether-a-go-go-related gene cardiac K+ channel. A model for bad behavior.
    Journal of medicinal chemistry, 2003, May-22, Volume: 46, Issue:11

    Topics: Cation Transport Proteins; DNA-Binding Proteins; Drug-Related Side Effects and Adverse Reactions; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Long QT Syndrome; Models, Molecular; Pharmaceutical Preparations; Potassium Channels; Potassium Channels, Voltage-Gated; Structure-Activity Relationship; Torsades de Pointes; Trans-Activators; Transcriptional Regulator ERG

2003

Other Studies

8 other study(ies) available for pimozide and Electrocardiogram QT Prolonged

ArticleYear
A comparison of the receptor binding and HERG channel affinities for a series of antipsychotic drugs.
    European journal of pharmacology, 2002, Aug-16, Volume: 450, Issue:1

    Topics: Animals; Antipsychotic Agents; Cation Transport Proteins; Cell Line; Clinical Trials as Topic; Cricetinae; DNA-Binding Proteins; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Long QT Syndrome; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Serotonin; Trans-Activators; Transcriptional Regulator ERG

2002
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers.
    Journal of medicinal chemistry, 2002, Aug-29, Volume: 45, Issue:18

    Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go-Go Potassium Channels; Long QT Syndrome; Models, Molecular; Molecular Conformation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2002
Mandatory electrocardiographic monitoring in young patients treated with psychoactive drugs.
    European child & adolescent psychiatry, 2013, Volume: 22, Issue:9

    Topics: Antipsychotic Agents; Child; Electrocardiography; Fluoxetine; Humans; Long QT Syndrome; Male; Pimozide; Selective Serotonin Reuptake Inhibitors; Tourette Syndrome

2013
CYP2D6 genotype information to guide pimozide treatment in adult and pediatric patients: basis for the U.S. Food and Drug Administration's new dosing recommendations.
    The Journal of clinical psychiatry, 2012, Volume: 73, Issue:9

    Topics: Adult; Child; Cytochrome P-450 CYP2D6; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Labeling; Drug Monitoring; Genetic Testing; Humans; Long QT Syndrome; Maximum Tolerated Dose; Metabolic Clearance Rate; Pimozide; Polymorphism, Genetic; Practice Guidelines as Topic; Precision Medicine; Tourette Syndrome; United States

2012
Changes in the product label for pimozide illustrate both the promises and the challenges of personalized medicine.
    The Journal of clinical psychiatry, 2012, Volume: 73, Issue:9

    Topics: Cytochrome P-450 CYP2D6; Dopamine Antagonists; Humans; Long QT Syndrome; Pimozide; Polymorphism, Genetic; Precision Medicine; Tourette Syndrome

2012
Practical application of guinea pig telemetry system for QT evaluation.
    The Journal of toxicological sciences, 2005, Volume: 30, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Antipsychotic Agents; Bepridil; Cisapride; Disease Models, Animal; Electrocardiography; Guinea Pigs; Haloperidol; Heart; Humans; Injections, Intravenous; Long QT Syndrome; Male; Nifedipine; Pimozide; Piperidines; Pyridines; Quinidine; Reproducibility of Results; Telemetry; Terfenadine; Thioridazine

2005
Pimozide (Orap) prolongs cardiac repolarization by blocking the rapid component of the delayed rectifier potassium current in native cardiac myocytes.
    Journal of cardiovascular pharmacology and therapeutics, 2001, Volume: 6, Issue:3

    Topics: Action Potentials; Animals; Antipsychotic Agents; Buffers; Guinea Pigs; Heart; In Vitro Techniques; Long QT Syndrome; Myocardium; Patch-Clamp Techniques; Perfusion; Pimozide; Potassium Channels; Tachycardia, Ventricular

2001
Pimozide and tricyclics.
    Hospital & community psychiatry, 1990, Volume: 41, Issue:4

    Topics: Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Drug Therapy, Combination; Electrocardiography; Humans; Long QT Syndrome; Pimozide

1990