pimozide has been researched along with Disease Models, Animal in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (33.33) | 18.7374 |
| 1990's | 2 (7.41) | 18.2507 |
| 2000's | 5 (18.52) | 29.6817 |
| 2010's | 8 (29.63) | 24.3611 |
| 2020's | 3 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Braisted, J; Dranchak, P; Earnest, TW; Gu, X; Hoon, MA; Inglese, J; Oliphant, E; Solinski, HJ | 1 |
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Chen, J; Feng, Z; Guo, J; Jia, H; Li, J; Li, R; Liu, X; Ren, W; Sun, K; Tian, Z; Wang, M; Wang, P; Wei, T; Yang, Y; Zhao, T; Zhong, J | 1 |
| Chen, JJ; Hou, YB; Ji, K; Sun, YT; Wang, HN; Zhang, LN; Zhao, ZF | 1 |
| Aggad, D; Armstrong, GA; Ciura, S; Drapeau, P; Ichida, J; Julien, JP; Kabashi, E; Korngut, L; La Fontaine, A; Liao, M; Maios, C; Martinez, J; Parker, JA; Patten, SA; Petrillo, J; Rafuse, V; Robitaille, R; Tremblay, E; Wen, XY; Zinman, L | 1 |
| Kuehn, BM | 1 |
| Julien, JP; Pozzi, S; Thammisetty, SS | 1 |
| Armstrong, GAB; Barden, C; Bose, P; Drapeau, P; Liao, M; Maios, C; Narasimhan, V; Parker, JA; Robitaille, R; Tremblay, E; Wen, XY | 1 |
| Buhrlage, SJ; Cuny, GD; D'Andrea, AD; Galinsky, I; Gray, NS; Hsieh, G; Huang, M; Mistry, H; Park, E; Parmar, K; Stone, RM | 1 |
| Chai, X; Gao, L; Guo, Y; Hu, B; Huang, M; Li, Y; Liu, Y; Lu, P; Ren, S; Xie, W; Xu, M; Yan, J; Zeng, S; Zhang, Y | 1 |
| Betz, AJ; Correa, M; Font, L; Sager, TN; Salamone, JD; Sink, KS; Valenta, J; Vontell, R; Worden, L | 1 |
| Jalali, A; Kawa, K; Larsen, C; Trevitt, J | 1 |
| Brennum, LT; Chrobak, JJ; Collins, LE; Galtieri, DJ; Hinman, JR; Hockemeyer, J; Müller, CE; Sager, TN; Salamone, JD | 1 |
| Betz, A; Felsted, J; Ishiwari, K; Salamone, JD; Weber, S | 1 |
| Abe, J; Hamada, Y; Harada, T; Hashimoto, K; Horii, I; Sawada, Y; Shiotani, M | 1 |
| Betz, AJ; Burgos, M; McLaughlin, PJ; Salamone, JD; Weber, SM | 1 |
| Burnham, WM; King, GA | 1 |
| Advis, JP; Ojeda, SR; Richards, JS | 1 |
| Fibiger, HC; Mason, ST | 1 |
| Anlezark, GM; Marsden, CD; Meldrum, BS | 1 |
| Borison, RL; Diamond, BI; Havdala, HS | 1 |
| Battista, AF; Goldstein, M; Matsumoto, Y; Miyamoto, T | 1 |
| Messiha, FS | 1 |
| Miyamoto, K | 1 |
| Carnoy, P; Puech, AJ; Simon, P; Soubrie, P | 1 |
| Lycke, E; Roos, BE | 1 |
| Duvoisin, RC; Marsden, CD | 1 |
1 trial(s) available for pimozide and Disease Models, Animal
| Article | Year |
|---|---|
Neuroleptics as therapeutic compounds stabilizing neuromuscular transmission in amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Animals; Antipsychotic Agents; Caenorhabditis elegans; Calcium Channels; Calcium Channels, T-Type; Disease Models, Animal; DNA-Binding Proteins; Drug Evaluation, Preclinical; Drug Tolerance; Female; Mice; Neuromuscular Junction; Neuromuscular Junction Diseases; Pimozide; Zebrafish; Zebrafish Proteins | 2017 |
26 other study(ies) available for pimozide and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
A self-designed CpG ODN enhanced the anti-melanoma effect of pimozide.
Topics: Animals; Antineoplastic Agents; Apoptosis; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; CpG Islands; Disease Models, Animal; Drug Therapy, Combination; Humans; Immunotherapy; Killer Cells, Natural; Male; Melanoma; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Oligodeoxyribonucleotides; Pimozide; Skin Neoplasms; Toll-Like Receptor 9 | 2020 |
The antipsychotic drug pimozide inhibits IgE-mediated mast cell degranulation and migration.
Topics: Anaphylaxis; Animals; Anti-Allergic Agents; Cell Degranulation; Cell Line; Cell Movement; Disease Models, Animal; Female; Immunoglobulin E; Mast Cells; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; Passive Cutaneous Anaphylaxis; Pimozide; Rats; Syk Kinase | 2020 |
Simple Models and Ice Bucket Challenge Fuel Progress in ALS Treatment.
Topics: Amyotrophic Lateral Sclerosis; Animals; Antipsychotic Agents; Caenorhabditis elegans; Clinical Trials, Phase II as Topic; Disease Models, Animal; Fund Raising; Humans; Neuromuscular Junction; Pimozide; Research Support as Topic; Social Media | 2018 |
Chronic Administration of Pimozide Fails to Attenuate Motor and Pathological Deficits in Two Mouse Models of Amyotrophic Lateral Sclerosis.
Topics: Age Factors; Amyotrophic Lateral Sclerosis; Animals; Anti-Dyskinesia Agents; Body Weight; Botulinum Toxins, Type A; Disease Models, Animal; DNA-Binding Proteins; Female; Humans; Male; Mice; Mice, Transgenic; Motor Activity; Movement Disorders; Muscle Strength; Mutation; Neuromuscular Agents; Neuromuscular Junction; Phosphopyruvate Hydratase; Pimozide; Statistics, Nonparametric; Superoxide Dismutase | 2018 |
The Novel Small Molecule TRVA242 Stabilizes Neuromuscular Junction Defects in Multiple Animal Models of Amyotrophic Lateral Sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Animals; Animals, Genetically Modified; C9orf72 Protein; Caenorhabditis elegans; Disease Models, Animal; DNA-Binding Proteins; Humans; Locomotion; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuromuscular Junction; Organ Culture Techniques; Pimozide; Superoxide Dismutase-1; Zebrafish | 2019 |
Small-molecule inhibitors of USP1 target ID1 degradation in leukemic cells.
Topics: Animals; Antineoplastic Agents; Arabidopsis Proteins; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Activation; Fanconi Anemia Complementation Group D2 Protein; High-Throughput Screening Assays; Homologous Recombination; Humans; Inhibitor of Differentiation Protein 1; Inhibitory Concentration 50; Leukemia; Mice; Pimozide; Protease Inhibitors; Protein Binding; Proteolysis; Ubiquitin-Specific Proteases; Ubiquitination; Xenograft Model Antitumor Assays | 2013 |
Hepatic Induction of Fatty Acid Binding Protein 4 Plays a Pathogenic Role in Sepsis in Mice.
Topics: Adipose Tissue; Animals; Cecum; Disease Models, Animal; Escherichia coli Infections; Fatty Acid-Binding Proteins; Female; Hepatocytes; Humans; Interleukin-6; Kupffer Cells; Ligation; Lipopolysaccharides; Liver; Mice; Mice, Inbred C57BL; Pimozide; Punctures; Sepsis | 2017 |
Effects of the adenosine A 2A antagonist KW 6002 (istradefylline) on pimozide-induced oral tremor and striatal c-Fos expression: comparisons with the muscarinic antagonist tropicamide.
Topics: Adenosine A2 Receptor Antagonists; Animals; Antipsychotic Agents; Biomarkers; Corpus Striatum; Disease Models, Animal; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Male; Masticatory Muscles; Muscarinic Antagonists; Pimozide; Proto-Oncogene Proteins c-fos; Purines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Dopamine D2; Tremor; Tropicamide; Up-Regulation | 2009 |
Differential effects of adenosine antagonists in two models of parkinsonian tremor.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Cholinergic Agonists; Disease Models, Animal; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Drug Synergism; Jaw; Male; Parkinsonian Disorders; Pimozide; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Sprague-Dawley; Tacrine; Theophylline; Tremor; Triazoles | 2009 |
Oral tremor induced by the muscarinic agonist pilocarpine is suppressed by the adenosine A2A antagonists MSX-3 and SCH58261, but not the adenosine A1 antagonist DPCPX.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Jaw; Male; Muscarinic Agonists; Pilocarpine; Pimozide; Pyrimidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Tremor; Triazoles; Xanthines | 2010 |
Validation of the tremulous jaw movement model for assessment of the motor effects of typical and atypical antipychotics: effects of pimozide (Orap) in rats.
Topics: Animals; Antipsychotic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Jaw; Male; Movement; Parkinson Disease, Secondary; Pimozide; Rats; Rats, Sprague-Dawley; Tremor | 2005 |
Practical application of guinea pig telemetry system for QT evaluation.
Topics: Animals; Anti-Arrhythmia Agents; Antipsychotic Agents; Bepridil; Cisapride; Disease Models, Animal; Electrocardiography; Guinea Pigs; Haloperidol; Heart; Humans; Injections, Intravenous; Long QT Syndrome; Male; Nifedipine; Pimozide; Piperidines; Pyridines; Quinidine; Reproducibility of Results; Telemetry; Terfenadine; Thioridazine | 2005 |
The muscarinic receptor antagonist tropicamide suppresses tremulous jaw movements in a rodent model of parkinsonian tremor: possible role of M4 receptors.
Topics: Animals; Atropine; Disease Models, Animal; Dopamine Antagonists; Dose-Response Relationship, Drug; Jaw; Male; Memory; Muscarinic Agonists; Muscarinic Antagonists; Parkinsonian Disorders; Pilocarpine; Pimozide; Random Allocation; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M4; Tremor; Tropicamide; Visual Perception | 2007 |
Effects of d-amphetamine and apomorphine in a new animal model of petit mal epilepsy.
Topics: Animals; Apomorphine; Dextroamphetamine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy, Absence; Habituation, Psychophysiologic; Male; Phenoxybenzamine; Photic Stimulation; Pimozide; Rats | 1980 |
Hyperprolactinemia-induced precocious puberty: studies on the mechanism(s) by which prolactin enhances ovarian progesterone responsiveness to gonadotropins in prepubertal rats.
Topics: Animals; Chorionic Gonadotropin; Disease Models, Animal; Estradiol; Female; Follicle Stimulating Hormone; Hypophysectomy; Ovary; Pimozide; Progesterone; Prolactin; Rats; Sexual Maturation; Sulpiride | 1981 |
Kainic acid lesions of the striatum in rats mimic the spontaneous motor abnormalities of Huntington's Disease.
Topics: Animals; Behavior, Animal; Choline O-Acetyltransferase; Corpus Striatum; Disease Models, Animal; Glutamate Decarboxylase; Huntington Disease; Kainic Acid; Male; Motor Activity; Pimozide; Pyrrolidines; Rats; Tyrosine 3-Monooxygenase | 1979 |
Acute dystonia as an idiosyncratic response to neuroleptics in baboons.
Topics: 5-Hydroxytryptophan; Acute Disease; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Haloperidol; Haplorhini; Humans; Levodopa; Movement Disorders; Papio; Parasympatholytics; Physostigmine; Pimozide; Receptors, Dopamine; Reserpine; Syndrome; Tranquilizing Agents | 1977 |
Chronic phenylethylamine stereotypy in rats: a new animal model for schizophrenia?
Topics: Animals; Behavior; Dextroamphetamine; Disease Models, Animal; Haloperidol; Humans; Male; Phenethylamines; Pimozide; Rats; Schizophrenia; Stereotyped Behavior; Time Factors | 1977 |
Effect of centrally acting drugs on experimental torticollis in monkeys.
Topics: Acetates; Alkaloids; Aminooxyacetic Acid; Animals; Brain Stem; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; Electromyography; Haloperidol; Haplorhini; Harmaline; Humans; Levodopa; Macaca mulatta; Methyltyrosines; Muscle Tonus; Pimozide; Tegmentum Mesencephali; Torticollis | 1976 |
Differential modulation of mouse brain biogenic amines by haloperidol and pimozide: implications in Tourette's syndrome.
Topics: Animals; Biogenic Amines; Brain; Disease Models, Animal; Haloperidol; Humans; Male; Mice; Mice, Inbred Strains; Motor Activity; Normetanephrine; Organ Specificity; Pimozide; Reference Values; Tourette Syndrome | 1990 |
Conditioned drug effects of pimozide, haloperidol and chlorpromazine on methamphetamine-induced behavior.
Topics: Animals; Arousal; Chlorpromazine; Conditioning, Classical; Disease Models, Animal; Dose-Response Relationship, Drug; Haloperidol; Male; Methamphetamine; Motor Activity; Neurocognitive Disorders; Orientation; Pimozide; Rats; Rats, Inbred Strains; Schizophrenic Psychology; Stereotyped Behavior | 1990 |
Performance deficit induced by low doses of dopamine agonists in rats. Toward a model for approaching the neurobiology of negative schizophrenic symptomatology?
Topics: Amisulpride; Animals; Antipsychotic Agents; Apomorphine; Disease Models, Animal; Male; Phenothiazines; Pimozide; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reinforcement Schedule; Reinforcement, Psychology; Schizophrenia; Schizophrenic Psychology; Sulpiride | 1986 |
Influence of changes in brain monoamine metabolism on behaviour of herpes simplex-infected mice.
Topics: Aggression; Animals; Apomorphine; Behavior, Animal; Brain; Clonidine; Dihydroxyphenylalanine; Disease Models, Animal; Disulfides; Dopamine; Dopamine beta-Hydroxylase; Fenclonine; Herpes Simplex; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Methyltyrosines; Mice; Motor Activity; Norepinephrine; Phenoxybenzamine; Pimozide; Receptors, Adrenergic; Serotonin; Tyrosine 3-Monooxygenase; Vaccinia; Virus Cultivation | 1974 |
Reversal of reserpine-induced bradykinesia by alpha-methyldopa--new light on its modus operandi.
Topics: Animals; Carbidopa; Chlorpromazine; Dihydroxyphenylalanine; Disease Models, Animal; Disulfiram; Dose-Response Relationship, Drug; Drug Synergism; Methyldopa; Mice; Movement Disorders; Parkinson Disease; Phenoxybenzamine; Pimozide; Reserpine | 1974 |