Page last updated: 2024-08-23

pimonidazole and Neoplasms

pimonidazole has been researched along with Neoplasms in 50 studies

Research

Studies (50)

Timeframe	Studies, this research(%)	All Research%
pre-1990	18 (36.00)	18.7374
1990's	5 (10.00)	18.2507
2000's	15 (30.00)	29.6817
2010's	9 (18.00)	24.3611
2020's	3 (6.00)	2.80

Authors

Authors	Studies
Labiano, S; Rodriguez-Ruiz, ME; Serrano-Mendioroz, I	1
Kanazawa, K; Maruyama, H; Uchiyama, Y; Yamagishi, S; Yamaura, T	1
Bai, R; Chen, C; Du, P; Gao, F; Li, J; Liu, J; Liu, S; Liu, T; Lu, X; Ma, M; Qin, F; Wang, Y; Zhou, H	1
Bayin, NS; Placantonakis, DG	1
Baker, JHE; Kozlowski, P; Minchinton, AI; Moosvi, F; Reinsberg, SA; Yung, A	1
Kosaka, M; Sakai-Sawada, K; Takei, N; Tamura, Y; Yoneda, A	1
Cabrales, P; Minchinton, A; Oronsky, B; Scicinski, J	1
Chen, Q; Deng, X; He, F; Huang, Y; Li, GC; Ling, CC; Liu, Y; Minami, A; Sun, X; Wen, B; Xing, L; Zanzonico, PB	1
Humm, JL; Li, XF; Ling, CC; Ma, Y; O'Donoghue, JA; Russell, J; Suehiro, M; Sun, X; Zhang, M	1
Möller, A; Young, RJ	1
Baumann, M; Beuthien-Baumann, B; Bussink, J; Eicheler, W; Krause, M; Rijken, P; Santiago, A; van der Kogel, AJ; Yaromina, A	1
Astner, ST; Bayer, C; Maftei, CA; Shi, K; Vaupel, P	1
Broggini-Tenzer, A; Hug, D; Orlowski, K; Pruschy, M; Rohrer Bley, C; Soltermann, A; Vuong, V; Zimmermann, M	1
Begg, AC	1
Frischer, JS; Holash, J; Huang, J; Kadenhe-Chiwishe, A; Kandel, JJ; Kim, ES; Lee, A; New, T; Pollyea, DA; Serur, A; Yamashiro, DJ; Yancopoulos, GD; Yokoi, A	1
Mechetner, E; Samoszuk, MK; Walter, J	1
Burgman, P; Burnazi, E; Cai, S; Finn, RD; Humm, JL; Lewis, JS; Ling, CC; O'Donoghue, JA; Pugachev, A; Ruan, S; Smith-Jones, P; Welch, MJ; Wen, B; Zanzonico, P	1
Campa, J; Carlin, S; Humm, JL; Larson, SM; Ling, CC; Pugachev, A; Ruan, S	1
Begg, AC; Bussink, J; Kaanders, JH; Ljungkvist, AS; Raleigh, JA; Rijken, PF; van der Kogel, AJ	1
Aquino-Parsons, C; Olive, P; Sobhanifar, S; Stanbridge, EJ	1
Chou, SC; Ji, X; Kleiter, MM; Lee, DY; Malarkey, DE; Raleigh, JA; Thrall, DE	1
Boerman, OC; Bussink, J; Kaanders, JH; Laverman, P; Lok, J; Oyen, WJ; Philippens, M; Troost, EG; van der Kogel, AJ	1
Burgman, P; Chen, Q; Diaz-Gonzalez, JA; Li, XF; Ling, CC; Russell, J; Shin, KH	1
Eykyn, TR; Gabellieri, C; Leach, MO	1
Coleman, CN; Phillips, TL; Urtasun, RC; Wasserman, TH	1
Denekamp, J; Fowler, JF; Williams, MV	1
Bleehen, NM; Roberts, JT; Walton, MI; Workman, P	2
Anderson, PJ; Bennett, MH; Dische, S; Minchinton, A; Saunders, MI; Stratford, MR; Tothill, M	1
Allen, JG; Dische, S; Lenox-Smith, I; Malcolm, SL; Saunders, MI	1
Denekamp, J; Fowler, JF; Hill, SA; Minchinton, AI; Stratford, MR	1
Groves, JK; Lee, A; Malcolm, SL	1
Allen, JG; Bishop, A; Dische, S; Fermont, D; Lenox-Smith, I; Malcolm, SL; Saunders, MI	1
Cowan, DS; Hicks, KO; Wilson, WR	1
Azuma, C; Raleigh, JA; Thrall, DE	1
Durand, RE; Raleigh, JA	1
Lehnert, S	1
Aquino-Parsons, C; Banáth, JP; Olive, PL	1
Bonn, D	1
Bleehen, NM; Maughan, TS; Newman, HF; Stenning, S; Ward, R; Workman, P	1
Bleehen, NM; Maughan, TS; Newman, HF; Ward, R; Workman, P	1
Bleehen, NM; Maughan, TS; Newman, HF; Workman, P	1
Bennett, MH; Dische, S; Orchard, R; Stratford, MR; Wardman, P	1
Bleehen, NM; Newman, HF; Workman, P	1
Bennett, MH; Des Rochers, C; Dische, S; Dunphy, EP; Minchinton, AI; Orchard, RA; Saunders, MI; Stratford, MR	1
Wasserman, TH	1
Bleehen, NM; Newman, HF; Ward, R; Workman, P	1
Brown, JM	1
Coleman, CN	1
Dische, S	1

Reviews

4 review(s) available for pimonidazole and Neoplasms

Article	Year
Clinical trials with hypoxic cell sensitizers: time to retrench or time to push forward? International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9 Topics: Clinical Trials as Topic; Combined Modality Therapy; Dexamethasone; Drug Evaluation; Etanidazole; Humans; Misonidazole; Neoplasms; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1984
Sensitizers and protectors in radiotherapy. Cancer, 1985, May-01, Volume: 55, Issue:9 Suppl Topics: Amifostine; Animals; Aziridines; Clinical Trials as Topic; Drug Evaluation; Etanidazole; Glutathione; Humans; Misonidazole; Neoplasms; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Protective Agents; Radiation-Sensitizing Agents; Radiotherapy	1985
Hypoxic cell radiosensitizers: expectations and progress in drug development. International journal of radiation oncology, biology, physics, 1985, Volume: 11, Issue:2 Topics: Clinical Trials as Topic; Combined Modality Therapy; Etanidazole; Humans; Metronidazole; Misonidazole; Neoplasms; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1985
Chemical sensitizers for hypoxic cells: a decade of experience in clinical radiotherapy. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1985, Volume: 3, Issue:2 Topics: Adrenal Cortex Hormones; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Etanidazole; Humans; Metronidazole; Misonidazole; Neoplasms; Nimorazole; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1985

Trials

10 trial(s) available for pimonidazole and Neoplasms

Article	Year
Clinical trials with hypoxic cell sensitizers: time to retrench or time to push forward? International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9 Topics: Clinical Trials as Topic; Combined Modality Therapy; Dexamethasone; Drug Evaluation; Etanidazole; Humans; Misonidazole; Neoplasms; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1984
Dose-response relationships for human tumors: implications for clinical trials of dose modifying agents. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9 Topics: Animals; Clinical Trials as Topic; Dose-Response Relationship, Radiation; Etanidazole; Humans; Mice; Misonidazole; Neoplasms; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1984
A phase I study of the hypoxic cell radiosensitizer Ro-03-8799. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9 Topics: Drug Evaluation; Humans; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents; Time Factors	1984
The combination of multiple doses of etanidazole and pimonidazole in 48 patients: a toxicity and pharmacokinetic study. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1991, Volume: 20 Suppl 1 Topics: Adult; Aged; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Combinations; Etanidazole; Female; Humans; Male; Middle Aged; Neoplasms; Nervous System Diseases; Nitroimidazoles; Radiation-Sensitizing Agents	1991
Abnormal clinical pharmacokinetics of the developmental radiosensitizers pimonidazole (Ro 03-8799) and etanidazole (SR 2508). International journal of radiation oncology, biology, physics, 1990, Volume: 18, Issue:5 Topics: Aged; Clinical Trials as Topic; Etanidazole; Humans; Male; Middle Aged; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents	1990
A multiple dose study of the combined radiosensitizers Ro 03-8799 (pimonidazole) and SR 2508 (etanidazole). International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:4 Topics: Drug Combinations; Etanidazole; Humans; Neoplasms; Nitroimidazoles; Peripheral Nervous System Diseases; Radiation-Sensitizing Agents	1989
Hypoxic cell radiosensitizers: illusion or elusion? International journal of radiation oncology, biology, physics, 1988, Volume: 15, Issue:3 Topics: Clinical Trials as Topic; Drug Therapy, Combination; Etanidazole; Humans; Neoplasms; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1988
Sensitizers and protectors in radiotherapy. Cancer, 1985, May-01, Volume: 55, Issue:9 Suppl Topics: Amifostine; Animals; Aziridines; Clinical Trials as Topic; Drug Evaluation; Etanidazole; Glutathione; Humans; Misonidazole; Neoplasms; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Protective Agents; Radiation-Sensitizing Agents; Radiotherapy	1985
Hypoxic cell radiosensitizers: expectations and progress in drug development. International journal of radiation oncology, biology, physics, 1985, Volume: 11, Issue:2 Topics: Clinical Trials as Topic; Combined Modality Therapy; Etanidazole; Humans; Metronidazole; Misonidazole; Neoplasms; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1985
Chemical sensitizers for hypoxic cells: a decade of experience in clinical radiotherapy. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1985, Volume: 3, Issue:2 Topics: Adrenal Cortex Hormones; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Etanidazole; Humans; Metronidazole; Misonidazole; Neoplasms; Nimorazole; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1985

Other Studies

40 other study(ies) available for pimonidazole and Neoplasms

Article	Year
Assessment of hypoxia by pimonidazole staining following radiotherapy. Methods in cell biology, 2022, Volume: 172 Topics: Biomarkers; Cell Hypoxia; Humans; Hypoxia; Neoplasms; Nitroimidazoles; Oxygen; Staining and Labeling; Tumor Microenvironment	2022
In Vivo Imaging of Tumor Hypoxia by Maintaining Green Fluorescence of 9-Aminoanthracene Under Hypoxic Conditions. Bioorganic & medicinal chemistry, 2023, 08-15, Volume: 91 Topics: Animals; Anthracenes; Cell Hypoxia; Diagnostic Imaging; Fluorescence; Hypoxia; Mice; Neoplasms; Tumor Hypoxia	2023
Hypoxia and pH co-triggered oxidative stress amplifier for tumor therapy. European journal of pharmacology, 2021, Aug-15, Volume: 905 Topics: Acrolein; Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Glutathione; Humans; Hydrogen-Ion Concentration; Mice; NADP; Neoplasms; Nitroimidazoles; Oxidative Stress; Reactive Oxygen Species; Tumor Hypoxia; Tumor Microenvironment	2021
Evaluation of Vascularity, Blood Perfusion, and Oxygen Tension in Tumor Xenografts with Fluorescent Microscopy. Methods in molecular biology (Clifton, N.J.), 2018, Volume: 1741 Topics: Animals; Disease Models, Animal; Fluorescent Antibody Technique; Heterografts; Humans; Hypoxia; Mice; Microscopy, Fluorescence; Neoplasm Staging; Neoplasms; Neovascularization, Pathologic; Nitroimidazoles; Oxygen	2018
Fast and sensitive dynamic oxygen-enhanced MRI with a cycling gas challenge and independent component analysis. Magnetic resonance in medicine, 2019, Volume: 81, Issue:4 Topics: Animals; Biomarkers; Biomarkers, Tumor; Cell Hypoxia; Cell Line, Tumor; Female; HCT116 Cells; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Mice; Neoplasm Transplantation; Neoplasms; Nitroimidazoles; Oxygen; Platelet Endothelial Cell Adhesion Molecule-1; Tumor Microenvironment	2019
ERO1α is a novel endogenous marker of hypoxia in human cancer cell lines. BMC cancer, 2019, May-29, Volume: 19, Issue:1 Topics: Animals; Antigens, Neoplasm; Biomarkers, Tumor; Carbonic Anhydrase IX; Cell Hypoxia; Cell Line, Tumor; HCT116 Cells; HeLa Cells; HT29 Cells; Humans; Membrane Glycoproteins; Mice; Neoplasm Transplantation; Neoplasms; Nitroimidazoles; Oxidoreductases	2019
RRx-001, an epigenetic-based radio- and chemosensitizer, has vascular normalizing effects on SCCVII and U87 tumors. Clinical epigenetics, 2016, Volume: 8 Topics: Actins; Animals; Antineoplastic Agents; Azetidines; Cell Hypoxia; Cell Line, Tumor; Epigenesis, Genetic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Neoplasm Transplantation; Neoplasms; Nitro Compounds; Nitroimidazoles; Tumor Microenvironment	2016
Noninvasive molecular imaging of hypoxia in human xenografts: comparing hypoxia-induced gene expression with endogenous and exogenous hypoxia markers. Cancer research, 2008, Oct-15, Volume: 68, Issue:20 Topics: Animals; Antigens, Neoplasm; Arabinofuranosyluracil; Autoradiography; Biomarkers; Carbonic Anhydrase IX; Carbonic Anhydrases; Cell Hypoxia; Etanidazole; Female; Gene Expression; Green Fluorescent Proteins; Herpesvirus 1, Human; HT29 Cells; Humans; Hydrocarbons, Fluorinated; Immunohistochemistry; Mice; Mice, Nude; Misonidazole; Neoplasm Transplantation; Neoplasms; Nitroimidazoles; Positron-Emission Tomography; Thymidine Kinase; Tissue Distribution; Transplantation, Heterologous	2008
Detection of hypoxia in microscopic tumors using 131I-labeled iodo-azomycin galactopyranoside (131I-IAZGP) digital autoradiography. European journal of nuclear medicine and molecular imaging, 2010, Volume: 37, Issue:2 Topics: Animals; Antigens, Neoplasm; Autoradiography; Biological Transport; Carbonic Anhydrase IX; Carbonic Anhydrases; Cell Hypoxia; Cell Line, Tumor; Female; Galactosides; Humans; Immunohistochemistry; Mice; Neoplasms; Nitroimidazoles; Radioactive Tracers; Radiographic Image Enhancement	2010
Immunohistochemical detection of tumour hypoxia. Methods in molecular biology (Clifton, N.J.), 2010, Volume: 611 Topics: Animals; Glucose Transporter Type 1; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Mice; Neoplasms; Nitroimidazoles	2010
Effect of cetuximab and fractionated irradiation on tumour micro-environment. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2010, Volume: 97, Issue:2 Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Carcinoma, Squamous Cell; Cell Line, Tumor; Cetuximab; Combined Modality Therapy; Dose Fractionation, Radiation; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Humans; Hypoxia; Male; Mice; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents; Signal Transduction; Transplantation, Heterologous; Xenograft Model Antitumor Assays	2010
Quantitative assessment of hypoxia subtypes in microcirculatory supply units of malignant tumors using (immuno-)fluorescence techniques. Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2011, Volume: 187, Issue:4 Topics: Benzimidazoles; Cell Hypoxia; Cell Line, Tumor; Diffusion; Humans; Microcirculation; Microscopy, Fluorescence; Microvessels; Neoplasms; Nitroimidazoles; Perfusion Imaging; Prognosis; Radiation-Sensitizing Agents; Tumor Cells, Cultured	2011
Dynamics of tumor hypoxia in response to patupilone and ionizing radiation. PloS one, 2012, Volume: 7, Issue:12 Topics: Animals; Biomarkers, Tumor; Cell Death; Cell Hypoxia; Cell Line, Tumor; Cobalt; Combined Modality Therapy; Epothilones; Genes, Reporter; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Luciferases; Mice; Mice, Nude; Neoplasms; Nitroimidazoles; Oxygen; Partial Pressure; Protein Structure, Tertiary; Radiation, Ionizing; Xenograft Model Antitumor Assays	2012
Is HIF-1alpha a good marker for tumor hypoxia? International journal of radiation oncology, biology, physics, 2003, Jul-15, Volume: 56, Issue:4 Topics: Animals; Biomarkers, Tumor; Cell Hypoxia; Flow Cytometry; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents; Transcription Factors	2003
TNP-470 promotes initial vascular sprouting in xenograft tumors. Molecular cancer therapeutics, 2004, Volume: 3, Issue:3 Topics: Angiogenesis Inhibitors; Angiography; Animals; Antibiotics, Antineoplastic; Apoptosis; Capillaries; Cell Line, Tumor; Cyclohexanes; Fluorescein; Humans; Hypoxia; Immunohistochemistry; In Situ Hybridization; In Situ Nick-End Labeling; Lectins; Mice; Mice, Nude; Microcirculation; Neoplasm Transplantation; Neoplasms; Neovascularization, Pathologic; Nitroimidazoles; O-(Chloroacetylcarbamoyl)fumagillol; Radiation-Sensitizing Agents; Sesquiterpenes; Vascular Endothelial Growth Factor A; Wilms Tumor	2004
Improved immunohistochemical method for detecting hypoxia gradients in mouse tissues and tumors. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2004, Volume: 52, Issue:6 Topics: Animals; Antibodies, Monoclonal; Cell Hypoxia; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Immunohistochemistry; Mice; Neoplasms; Nitroimidazoles; Organ Specificity	2004
Assessment of regional tumor hypoxia using 18F-fluoromisonidazole and 64Cu(II)-diacetyl-bis(N4-methylthiosemicarbazone) positron emission tomography: Comparative study featuring microPET imaging, Po2 probe measurement, autoradiography, and fluorescent mic International journal of radiation oncology, biology, physics, 2005, Apr-01, Volume: 61, Issue:5 Topics: Animals; Autoradiography; Benzimidazoles; Cell Hypoxia; Coordination Complexes; Fluorodeoxyglucose F18; Humans; Immunohistochemistry; Male; Microscopy, Fluorescence; Misonidazole; Neoplasms; Nitroimidazoles; Organometallic Compounds; Positron-Emission Tomography; Radiation-Sensitizing Agents; Radiopharmaceuticals; Rats; Rats, Nude; Thiosemicarbazones; Transplantation, Heterologous	2005
Dependence of FDG uptake on tumor microenvironment. International journal of radiation oncology, biology, physics, 2005, Jun-01, Volume: 62, Issue:2 Topics: Animals; Autoradiography; Benzimidazoles; Bromodeoxyuridine; Cell Hypoxia; Cell Proliferation; Coloring Agents; Fluorodeoxyglucose F18; Glucose; Male; Mice; Mice, Nude; Neoplasms; Nitroimidazoles; Prostatic Neoplasms; Radiopharmaceuticals	2005
Hypoxic cell turnover in different solid tumor lines. International journal of radiation oncology, biology, physics, 2005, Jul-15, Volume: 62, Issue:4 Topics: Animals; Benzimidazoles; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Coloring Agents; Half-Life; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Nitroimidazoles; Time Factors	2005
Reduced expression of hypoxia-inducible factor-1alpha in perinecrotic regions of solid tumors. Cancer research, 2005, Aug-15, Volume: 65, Issue:16 Topics: Animals; Antigens, Neoplasm; Astrocytoma; Biomarkers, Tumor; Biopsy; Carbonic Anhydrase IX; Carbonic Anhydrases; Cell Hypoxia; Cell Line, Tumor; Colonic Neoplasms; Female; Flow Cytometry; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Image Processing, Computer-Assisted; Mice; Mice, SCID; Necrosis; Neoplasms; Nitroimidazoles; Transcription Factors; Transplantation, Heterologous; Uterine Cervical Neoplasms	2005
A comparison of oral and intravenous pimonidazole in canine tumors using intravenous CCI-103F as a control hypoxia marker. International journal of radiation oncology, biology, physics, 2006, Feb-01, Volume: 64, Issue:2 Topics: Administration, Oral; Animals; Area Under Curve; Cell Hypoxia; Cell Line; Cricetinae; Cricetulus; Dog Diseases; Dogs; Feasibility Studies; Hydrogen-Ion Concentration; Injections, Intravenous; Neoplasms; Nitroimidazoles	2006
Imaging hypoxia after oxygenation-modification: comparing [18F]FMISO autoradiography with pimonidazole immunohistochemistry in human xenograft tumors. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2006, Volume: 80, Issue:2 Topics: Animals; Autoradiography; Carcinoma, Squamous Cell; Cell Hypoxia; Fluorine Radioisotopes; Glioblastoma; Head and Neck Neoplasms; Humans; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Nude; Misonidazole; Neoplasms; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Radionuclide Imaging	2006
Detecting changes in tumor hypoxia with carbonic anhydrase IX and pimonidazole. Cancer biology & therapy, 2007, Volume: 6, Issue:1 Topics: Animals; Antigens, Neoplasm; Biomarkers; Carbonic Anhydrase IX; Carbonic Anhydrases; Cell Hypoxia; Cell Line, Tumor; Humans; Immunohistochemistry; Mice; Neoplasms; Nitroimidazoles; Oxygen Consumption	2007
Conformational exchange in pimonidazole--a hypoxia marker. Magnetic resonance in chemistry : MRC, 2007, Volume: 45, Issue:8 Topics: Animals; Biomarkers; Cell Hypoxia; Humans; Magnetic Resonance Spectroscopy; Molecular Conformation; Neoplasms; Nitroimidazoles	2007
The clinical testing of Ro 03-8799--pharmacokinetics, toxicology, tissue and tumor concentrations. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9 Topics: Drug Evaluation; Female; Humans; Male; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents; Time Factors; Tissue Distribution	1984
The pharmacokinetics of a new radiosensitiser, Ro 03-8799 in humans. European journal of clinical pharmacology, 1984, Volume: 27, Issue:4 Topics: Adult; Aged; Blood Proteins; Erythrocytes; Feces; Female; Humans; Injections, Intravenous; Kinetics; Male; Middle Aged; Neoplasms; Nitroimidazoles; Oxides; Protein Binding; Radiation-Sensitizing Agents; Time Factors	1984
Radiosensitization of a mouse tumour by Ro 03-8799: acute and protracted administration. International journal of radiation biology and related studies in physics, chemistry, and medicine, 1983, Volume: 44, Issue:2 Topics: Animals; Injections, Intraperitoneal; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Neoplasm Transplantation; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents	1983
High-performance liquid chromatographic analysis of the new hypoxic cell radiosensitiser, Ro 03-8799, in biological samples. Journal of chromatography, 1983, Apr-08, Volume: 273, Issue:2 Topics: Animals; Bile; Chromatography, High Pressure Liquid; Erythrocytes; Humans; Neoplasms; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Rats; Spectrophotometry, Ultraviolet; Time Factors	1983
The radiosensitizer Ro 03-8799 and the concentrations which may be achieved in human tumours: a preliminary study. British journal of cancer, 1982, Volume: 46, Issue:5 Topics: Adult; Aged; Female; Half-Life; Humans; Male; Necrosis; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents	1982
Multicellular membranes as an in vitro model for extravascular diffusion in tumours. The British journal of cancer. Supplement, 1996, Volume: 27 Topics: Acridines; Animals; Cell Hypoxia; Cell Membrane; Cricetinae; Cricetulus; Diffusion; In Vitro Techniques; Misonidazole; Neoplasms; Nitroimidazoles; Phenanthridines	1996
Longevity of pimonidazole adducts in spontaneous canine tumors as an estimate of hypoxic cell lifetime. Radiation research, 1997, Volume: 148, Issue:1 Topics: Animals; Cell Survival; DNA Adducts; DNA, Neoplasm; Dog Diseases; Dogs; Hypoxia; Neoplasms; Nitroimidazoles	1997
Identification of nonproliferating but viable hypoxic tumor cells in vivo. Cancer research, 1998, Aug-15, Volume: 58, Issue:16 Topics: Animals; Bromodeoxyuridine; Cell Division; Cell Hypoxia; Cell Separation; Flow Cytometry; Humans; Mice; Mice, SCID; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents; Transplantation, Heterologous; Tumor Cells, Cultured	1998
Prediction of tumor response to therapy: molecular markers and the microenvironment. Apoptosis and chips: an overview of the proceedings. Radiation research, 2000, Volume: 154, Issue:2 Topics: Apoptosis; Biomarkers, Tumor; Biopsy; Cell Cycle; Cell Hypoxia; Cell Survival; Comet Assay; DNA Ligases; Enzyme Activation; Genes, ras; Humans; Immunohistochemistry; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms; Nitroimidazoles; Oligonucleotide Array Sequence Analysis; Predictive Value of Tests; Radiation Tolerance; Radiotherapy Dosage; Tumor Cells, Cultured	2000
Measuring hypoxia in solid tumours--is there a gold standard? Acta oncologica (Stockholm, Sweden), 2001, Volume: 40, Issue:8 Topics: Biopsy, Needle; Comet Assay; Humans; Hypoxia; Microelectrodes; Neoplasms; Nitroimidazoles; Palliative Care; Predictive Value of Tests; Radiation-Sensitizing Agents; Radiotherapy; Reference Values	2001
Why do hypoxic cells behave badly? The Lancet. Oncology, 2000, Volume: 1 Topics: Cell Hypoxia; Humans; Immunohistochemistry; Infusions, Intravenous; Neoplasm Invasiveness; Neoplasms; Nitroimidazoles; Oxygen; Prognosis; Sensitivity and Specificity; Tumor Cells, Cultured	2000
The uptake of the radiosensitizing compound Ro 03-8799 (Pimonidazole) in human tumors. International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:4 Topics: Breast Neoplasms; Female; Humans; Melanoma; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents; Rectal Neoplasms; Uterine Cervical Neoplasms	1989
A phase I study of the combination of two hypoxic cell radiosensitizers, Ro 03-8799 and SR-2508: toxicity and pharmacokinetics. International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:7 Topics: Adolescent; Adult; Aged; Combined Modality Therapy; Drug Combinations; Drug Evaluation; Etanidazole; Humans; Middle Aged; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents	1986
Concentrations achieved in human tumors after administration of misonidazole, SR-2508 and Ro 03-8799. International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:7 Topics: Aged; Etanidazole; Female; Humans; Male; Middle Aged; Misonidazole; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents	1986
The multi-dose clinical tolerance and pharmacokinetics of the combined radiosensitizers, Ro 03-8799 (pimonidazole) and SR 2508 (etanidazole). International journal of radiation oncology, biology, physics, 1988, Volume: 15, Issue:5 Topics: Adult; Aged; Combined Modality Therapy; Drug Therapy, Combination; Etanidazole; Humans; Middle Aged; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents	1988
A clinical phase I toxicity study of Ro 03-8799: plasma, urine, tumour and normal brain pharmacokinetics. The British journal of radiology, 1986, Volume: 59, Issue:698 Topics: Astrocytoma; Brain; Brain Diseases; Brain Neoplasms; Dose-Response Relationship, Drug; Drug Evaluation; Humans; Kinetics; Neoplasms; Nitroimidazoles	1986