Page last updated: 2024-08-23

pimonidazole and Disease Models, Animal

pimonidazole has been researched along with Disease Models, Animal in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (2.56)18.2507
2000's12 (30.77)29.6817
2010's25 (64.10)24.3611
2020's1 (2.56)2.80

Authors

AuthorsStudies
Dąbrowski, JM; Elas, M; Gonet, M; Karwicka, M; Pucelik, B1
Cramer, RA; Grahl, N; Kowalski, CH1
Jayagopal, A; McCollum, GW; Penn, JS; Uddin, MI; Yang, R1
Bayin, NS; Placantonakis, DG1
Evans, RG; Ngo, JP; Ow, CPC; Sayakkarage, A; Ullah, MM1
Hansen-Schwartz, J; Hasseldam, H; Hou, J; Johansen, FF; Munkholm, N1
Enjoji, M; Kato, M; Kotoh, K; Masaki, Y; Miyazaki, M; Nakamuta, M; Takayanagi, R; Tanaka, K; Tanaka, M1
Abdelkader, A; Eppel, GA; Evans, RG; Ho, J; Ow, CP; Rajapakse, NW; Schlaich, MP1
Araujo, AP; Giorgio, S1
Galoforo, S; Grills, IS; Kane, JL; Krueger, SA; Marples, B; Wilson, GD; Wobb, J1
Fourcade, O; Geeraerts, T; Gonzalez, L; Kerhuel, L; Luzi, A; Mrozek, S1
Barnes, SL; Kang, H; Quarles, CC; Sanchez, V; Sorace, AG; Syed, AK; Yankeelov, TE1
He, T; Xing, Y; Yang, N; Zhang, W1
Crukley, C; Desjardins, L; Hadway, J; Lee, TY; Morrison, L; Stewart, E; Wang, Y1
Al-Shabrawey, M; Bartoli, M; Behzadian, MA; Caldwell, RB; Caldwell, RW; El-Remessy, AB; Istanboli, M; Labazi, M; Marcus, DM1
Ackerstaff, E; Carlin, S; Cho, H; Humm, JL; Koutcher, JA; Ling, CC; Lupu, ME; O'Donoghue, J; Rizwan, A; Wang, Y; Zanzonico, PB1
Fujibayashi, Y; Fujieda, S; Furukawa, T; Kobayashi, M; Kudo, T; Mori, T; Oh, M; Tanaka, T1
Boutrid, H; Cebulla, CM; Feuer, WJ; Jockovich, ME; Lampidis, TJ; Murray, TG; Piña, Y1
Baumann, M; Eckardt, A; Eicheler, W; Schuetze, C; Thames, H; Yaromina, A; Zips, D1
Busk, M; Bussink, J; Hansen, KV; Horsman, MR; Jakobsen, S; Overgaard, J; van der Kogel, A1
Aihara, K; Akaike, M; Fukuhara, Y; Gonzalez, FJ; Ishizawa, K; Izawa-Ishizawa, Y; Kanbara, T; Kitagawa, T; Kurobe, H; Lei, Y; Ono, S; Ripen, AM; Takahama, Y; Tamaki, T; Tomita, S; Ueki, M; Ueno, M; Urata, M; Yoshizumi, M1
Baumann, M; Flentje, M; Jakob, PM; Melkus, G; Mörchel, P; Yaromina, A; Zips, D1
Baumann, M; Dörfler, A; Eicheler, W; Hering, S; Leichtner, T; Thames, H; Yaromina, A; Zhou, X; Zips, D1
Boutrid, H; Celdran, M; Feuer, W; Hernandez, E; Houston, SK; Lampidis, TJ; Murray, TG; Piña, Y; Shi, W1
Babaev, AA; Golubiatnikov, GY; Ivanova, IP; Kamensky, VA; Maslennikova, AV; Orlova, AG; Plekhanov, VI; Prianikova, TI; Shakhova, NM; Snopova, LB; Turchin, IV1
Cecic, IK; Erler, JT; Felsher, D; Giaccia, AJ; Graves, EE; Le, QT; Sayles, L; Sweet-Cordero, A; Tran, PT; Vilalta, M1
Forsback, S; Heinonen, SE; Knuuti, J; Laine, VJ; Roivainen, A; Saraste, A; Saukko, P; Silvola, JM; Ylä-Herttuala, S1
Bifani, P; Dartois, V; Heng, Y; Hervé, M; Kiass, M; Mathys, V; Seah, PG; Siew, JY; Singhal, A; Tay, HC1
Combes, V; Grau, GE; Hempel, C; Hunt, NH; Kurtzhals, JA1
Bali, S; Bhutta, MF; Brown, SD; Cheeseman, MT; Hilton, H; Hough, TA; Parker, A; Pathak, P; Potter, PK; Purnell, T; Romero, MR; Tyrer, HE; Vizor, L; Vowell, K; Wells, S; Williams, D1
Civelek, AC; Huang, T; Jiang, H; Li, J; Li, XF; Ng, CK; Postel, GC; Shen, B1
Bachmann, S; Dietrich, A; Kaminski, H; Mathia, S; Mrowka, R; Mutig, K; Paliege, A; Rosenberger, C1
Angus, PW; Burrell, LM; Cooper, ME; Lew, RA; Paizis, G; Schembri, JM; Shaw, T; Smith, AI; Tikellis, C; Warner, FJ; Zuilli, A1
Aly, S; Bange, FC; Brandau, S; Ehlers, S; Keller, C; Malm, S; Malzan, A; Wagner, K1
Allen, SS; Barry, CE; Carrillo, J; Cho, SN; Eum, SY; Flynn, JL; Gonzales, J; Klein, E; Lee, EG; Lin, PL; Manjunatha, U; McMurray, DN; Park, SK; Raleigh, JA; Ray, SM; Taylor, K; Via, LE1
Arteel, GE; Iimuro, Y; Raleigh, JA; Thurman, RG; Yin, M1
Bernsen, HJ; Jeuken, JW; Peters, H; Raleigh, JA; Rijken, PF; van der Kogel, AJ; Wesseling, P1
Bussink, J; Kaanders, JH; Strik, AM; van der Kogel, AJ1
Thurman, RG1

Reviews

1 review(s) available for pimonidazole and Disease Models, Animal

ArticleYear
Sex-related liver injury due to alcohol involves activation of Kupffer cells by endotoxin.
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2000, Volume: 14 Suppl D

    Topics: Animals; Cell Hypoxia; Diet; Disease Models, Animal; Endotoxins; Ethanol; Female; Kupffer Cells; Lipopolysaccharide Receptors; Lipopolysaccharides; Liver Diseases, Alcoholic; Male; Nitroimidazoles; Radiation-Sensitizing Agents; Rats; Sex Factors; Tumor Necrosis Factor-alpha

2000

Other Studies

38 other study(ies) available for pimonidazole and Disease Models, Animal

ArticleYear
Effects of Photodynamic Therapy with Redaporfin on Tumor Oxygenation and Blood Flow in a Lung Cancer Mouse Model.
    Scientific reports, 2019, 09-02, Volume: 9, Issue:1

    Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Kaplan-Meier Estimate; Lung Neoplasms; Mice, Inbred C57BL; Nitroimidazoles; Oxygen; Perfusion; Photochemotherapy; Porphyrins; Sulfonamides; Tissue Distribution; Tumor Hypoxia; Vascular Endothelial Growth Factor A

2019
Detection of Low Oxygen Microenvironments in a Murine Model of Invasive Pulmonary Aspergillosis Using Pimonidazole.
    Methods in molecular biology (Clifton, N.J.), 2021, Volume: 2260

    Topics: Animals; Aspergillus fumigatus; Cell Hypoxia; Cellular Microenvironment; Disease Models, Animal; Fluorescent Antibody Technique; Host-Pathogen Interactions; Invasive Pulmonary Aspergillosis; Lung; Mice; Microscopy, Fluorescence; Nitroimidazoles; Oxygen

2021
In Vivo Imaging of Retinal Hypoxia Using HYPOX-4-Dependent Fluorescence in a Mouse Model of Laser-Induced Retinal Vein Occlusion (RVO).
    Investigative ophthalmology & visual science, 2017, 07-01, Volume: 58, Issue:9

    Topics: Animals; Disease Models, Animal; Fluorescein Angiography; Fluoresceins; Fluorescent Dyes; Hypoxia; Image Processing, Computer-Assisted; Macular Edema; Male; Mice; Mice, Inbred C57BL; Nitroimidazoles; Radiation-Sensitizing Agents; Retinal Neovascularization; Retinal Vein; Retinal Vein Occlusion; Tomography, Optical Coherence

2017
Evaluation of Vascularity, Blood Perfusion, and Oxygen Tension in Tumor Xenografts with Fluorescent Microscopy.
    Methods in molecular biology (Clifton, N.J.), 2018, Volume: 1741

    Topics: Animals; Disease Models, Animal; Fluorescent Antibody Technique; Heterografts; Humans; Hypoxia; Mice; Microscopy, Fluorescence; Neoplasm Staging; Neoplasms; Neovascularization, Pathologic; Nitroimidazoles; Oxygen

2018
Detection of cellular hypoxia by pimonidazole adduct immunohistochemistry in kidney disease: methodological pitfalls and their solution.
    American journal of physiology. Renal physiology, 2019, 08-01, Volume: 317, Issue:2

    Topics: Acute Kidney Injury; Animals; Antibodies, Monoclonal; Antibody Specificity; Artifacts; Cell Hypoxia; Disease Models, Animal; False Positive Reactions; Immunohistochemistry; Kidney; Nitroimidazoles; Polycystic Kidney Diseases; Predictive Value of Tests; Rats, Inbred Lew; Rats, Sprague-Dawley; Renal Insufficiency, Chronic; Reperfusion Injury; Reproducibility of Results

2019
Remote post-conditioning reduces hypoxic damage early after experimental stroke.
    Neurological research, 2013, Volume: 35, Issue:4

    Topics: Animals; Blotting, Western; Disease Models, Animal; Femoral Vein; Hypoxia, Brain; Male; Nitroimidazoles; Radiation-Sensitizing Agents; Rats; Rats, Wistar; Reperfusion Injury; Stroke

2013
Intrahepatic microcirculatory disorder, parenchymal hypoxia and NOX4 upregulation result in zonal differences in hepatocyte apoptosis following lipopolysaccharide- and D-galactosamine-induced acute liver failure in rats.
    International journal of molecular medicine, 2014, Volume: 33, Issue:2

    Topics: Aldehydes; Animals; Apoptosis; Caspase 3; Disease Models, Animal; Fluconazole; Galactosamine; Hepatocytes; Hypoxia-Inducible Factor 1; Lipopolysaccharides; Liver; Liver Failure, Acute; Macrophages; Male; Microcirculation; NADPH Oxidase 4; NADPH Oxidases; Nitroimidazoles; Oxidative Stress; Rats; Rats, Wistar; Rhodamines; Up-Regulation

2014
Renal oxygenation in acute renal ischemia-reperfusion injury.
    American journal of physiology. Renal physiology, 2014, May-01, Volume: 306, Issue:9

    Topics: Acute Kidney Injury; Animals; Biomarkers; Cell Hypoxia; Disease Models, Animal; Fluorescence; Glomerular Filtration Rate; Hemoglobins; Immunohistochemistry; Kidney; Laser-Doppler Flowmetry; Male; Models, Cardiovascular; Nitroimidazoles; Oxygen; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Renal Circulation; Reperfusion Injury; Reproducibility of Results; Severity of Illness Index; Time Factors

2014
Immunohistochemical evidence of stress and inflammatory markers in mouse models of cutaneous leishmaniosis.
    Archives of dermatological research, 2015, Volume: 307, Issue:8

    Topics: Animals; Biomarkers; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Immunohistochemistry; Inflammation; Leishmania; Leishmaniasis, Cutaneous; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nitric Oxide; Nitroimidazoles; p38 Mitogen-Activated Protein Kinases; Vascular Endothelial Growth Factor A

2015
The Effects of Pulsed Radiation Therapy on Tumor Oxygenation in 2 Murine Models of Head and Neck Squamous Cell Carcinoma.
    International journal of radiation oncology, biology, physics, 2015, Jul-15, Volume: 92, Issue:4

    Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Coloring Agents; Disease Models, Animal; Female; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Heterografts; Mice; Mice, Nude; Misonidazole; Neoplasm Recurrence, Local; Nitroimidazoles; Oxygen Consumption; Positron-Emission Tomography; Radiopharmaceuticals; Squamous Cell Carcinoma of Head and Neck; Tumor Burden

2015
Cerebral and extracerebral vulnerability to hypoxic insults after diffuse traumatic brain injury in rats.
    Brain research, 2016, 09-01, Volume: 1646

    Topics: Animals; Arterial Pressure; Brain; Brain Injuries, Traumatic; Disease Models, Animal; Hypotension; Hypoxia; Hypoxia, Brain; Kidney; Liver; Male; Myocardium; Nitroimidazoles; Rats; Rats, Sprague-Dawley

2016
Quantitative [
    Molecular imaging and biology, 2017, Volume: 19, Issue:1

    Topics: Animals; Biomarkers, Tumor; Cell Line, Tumor; Disease Models, Animal; Female; Fluorescent Antibody Technique; Mammary Neoplasms, Animal; Misonidazole; Nitroimidazoles; Positron-Emission Tomography; Receptor, ErbB-2; Trastuzumab; Tumor Burden; Tumor Hypoxia

2017
Silencing of galectin-1 inhibits retinal neovascularization and ameliorates retinal hypoxia in a murine model of oxygen-induced ischemic retinopathy.
    Experimental eye research, 2017, Volume: 159

    Topics: Animals; Animals, Newborn; Blotting, Western; Disease Models, Animal; Galectin 1; Gene Silencing; Hypoxia; Intravitreal Injections; Ischemia; Mice; Mice, Inbred C57BL; Nitroimidazoles; Oxygen; Real-Time Polymerase Chain Reaction; Retinal Neovascularization; RNA; RNA, Messenger

2017
Assessment of intratumor hypoxia by integrated 18F-FDG PET / perfusion CT in a liver tumor model.
    PloS one, 2017, Volume: 12, Issue:3

    Topics: Animals; Disease Models, Animal; Fluorodeoxyglucose F18; Glucose; Humans; Hypoxia; Liver Neoplasms; Male; Neovascularization, Pathologic; Nitroimidazoles; Oxygen Consumption; Perfusion; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Rabbits

2017
HMG-CoA reductase inhibitors (statin) prevents retinal neovascularization in a model of oxygen-induced retinopathy.
    Investigative ophthalmology & visual science, 2009, Volume: 50, Issue:10

    Topics: Animals; Blotting, Western; Capillaries; Disease Models, Animal; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Indoles; Infant, Newborn; Intercellular Adhesion Molecule-1; Lipid Peroxidation; Mice; Nitroimidazoles; Oxygen; Phosphorylation; Retinal Neovascularization; Retinal Vessels; Retinopathy of Prematurity; STAT3 Transcription Factor; Superoxides; Vascular Endothelial Growth Factor A

2009
Noninvasive multimodality imaging of the tumor microenvironment: registered dynamic magnetic resonance imaging and positron emission tomography studies of a preclinical tumor model of tumor hypoxia.
    Neoplasia (New York, N.Y.), 2009, Volume: 11, Issue:3

    Topics: Animals; Autoradiography; Cell Hypoxia; Disease Models, Animal; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Misonidazole; Nitroimidazoles; Positron-Emission Tomography; Prostatic Neoplasms; Radiopharmaceuticals; Rats

2009
Radio-copper-labeled Cu-ATSM: an indicator of quiescent but clonogenic cells under mild hypoxia in a Lewis lung carcinoma model.
    Nuclear medicine and biology, 2009, Volume: 36, Issue:4

    Topics: Animals; Autoradiography; Bromodeoxyuridine; Carcinoma, Lewis Lung; Cell Proliferation; Colony-Forming Units Assay; Coordination Complexes; Copper Radioisotopes; Disease Models, Animal; Fluorodeoxyglucose F18; Hypoxia; Image Processing, Computer-Assisted; Immunohistochemistry; Ki-67 Antigen; Male; Mice; Nitroimidazoles; Organometallic Compounds; Positron-Emission Tomography; Staining and Labeling; Thiosemicarbazones

2009
Increased hypoxia following vessel targeting in a murine model of retinoblastoma.
    Investigative ophthalmology & visual science, 2009, Volume: 50, Issue:12

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Carboplatin; Disease Models, Animal; Hypoxia; Mice; Mice, Transgenic; Microscopy, Confocal; Neovascularization, Pathologic; Nitroimidazoles; Pregnadienediols; Retinal Neoplasms; Retinoblastoma

2009
Core needle biopsies for determination of the microenvironment in individual tumours for longitudinal radiobiological studies.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2009, Volume: 92, Issue:3

    Topics: Animals; Biopsy, Needle; Carcinoma, Squamous Cell; Confidence Intervals; Disease Models, Animal; Dose Fractionation, Radiation; Dose-Response Relationship, Radiation; Environment; Female; Humans; Hypoxia; Immunohistochemistry; Longitudinal Studies; Male; Mice; Mice, Nude; Neoplasm Transplantation; Nitroimidazoles; Probability; Radiobiology; Random Allocation; Reference Values

2009
Can hypoxia-PET map hypoxic cell density heterogeneity accurately in an animal tumor model at a clinically obtainable image contrast?
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2009, Volume: 92, Issue:3

    Topics: Animals; Carcinoma, Squamous Cell; Cell Count; Cell Hypoxia; Disease Models, Animal; Female; Hypoxia; Mice; Mice, Inbred C3H; Nitroimidazoles; Oxygen; Positron-Emission Tomography; Radiopharmaceuticals; Random Allocation; Sensitivity and Specificity; Tissue Distribution

2009
Role of hypoxia-inducible factor 1alpha in T cells as a negative regulator in development of vascular remodeling.
    Arteriosclerosis, thrombosis, and vascular biology, 2010, Volume: 30, Issue:2

    Topics: Animals; Antibody Formation; Arteriosclerosis; Cell Hypoxia; Cell Proliferation; Chemokine CXCL12; Chemotaxis, Leukocyte; Cytokines; Disease Models, Animal; Femoral Artery; Hyperplasia; Hypoxia-Inducible Factor 1, alpha Subunit; Immunity, Cellular; Immunohistochemistry; Lymphocyte Activation; Male; Mice; Mice, Knockout; Nitroimidazoles; Receptors, Antigen, T-Cell; T-Lymphocytes; Thymus Gland; Time Factors; Tunica Intima

2010
Correlating quantitative MR measurements of standardized tumor lines with histological parameters and tumor control dose.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2010, Volume: 96, Issue:1

    Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Disease Models, Animal; Dose Fractionation, Radiation; Dose-Response Relationship, Radiation; Humans; Immunohistochemistry; Lactic Acid; Magnetic Resonance Imaging; Mice; Mice, Nude; Neoplasm Transplantation; Nitroimidazoles; Oxygen Consumption; Radiation Dosage; Radiation-Sensitizing Agents; Sensitivity and Specificity; Transplantation, Heterologous

2010
Radiobiological hypoxia, histological parameters of tumour microenvironment and local tumour control after fractionated irradiation.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2010, Volume: 96, Issue:1

    Topics: Animals; Carcinoma, Squamous Cell; Cell Division; Cell Hypoxia; Confidence Intervals; Disease Models, Animal; Dose Fractionation, Radiation; Dose-Response Relationship, Radiation; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; Nitroimidazoles; Radiation Tolerance; Radiation-Sensitizing Agents; Radiobiology; Transplantation, Heterologous; Tumor Microenvironment

2010
Focal, periocular delivery of 2-deoxy-D-glucose as adjuvant to chemotherapy for treatment of advanced retinoblastoma.
    Investigative ophthalmology & visual science, 2010, Volume: 51, Issue:12

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Deoxyglucose; Disease Models, Animal; Drug Delivery Systems; Hypoxia; Mice; Mice, Transgenic; Microscopy, Fluorescence; Nitroimidazoles; Retinal Neoplasms; Retinoblastoma; Tumor Burden

2010
Comparative study of tumor hypoxia by diffuse optical spectroscopy and immunohistochemistry in two tumor models.
    Journal of biophotonics, 2010, Volume: 3, Issue:12

    Topics: Animals; Biomarkers, Tumor; Brain Neoplasms; Diffusion; Disease Models, Animal; Female; Hemoglobins; Hypoxia; Immunohistochemistry; Lymph Nodes; Male; Medical Oncology; Nitroimidazoles; Optical Devices; Oxygen; Radiation-Sensitizing Agents; Rats; Spectrum Analysis

2010
Hypoxia in models of lung cancer: implications for targeted therapeutics.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2010, Oct-01, Volume: 16, Issue:19

    Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Electrodes; Histones; Humans; Lung Neoplasms; Male; Mice; Mice, Nude; Neoplasms, Experimental; Nitrogen Mustard Compounds; Nitroimidazoles; Oxygen; Positron-Emission Tomography; Proto-Oncogene Proteins c-myc; ras Proteins

2010
Detection of hypoxia by [18F]EF5 in atherosclerotic plaques in mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2011, Volume: 31, Issue:5

    Topics: Analysis of Variance; Animals; Aorta; Apolipoprotein B-100; Atherosclerosis; Autoradiography; Disease Models, Animal; Etanidazole; Female; Fluorine Radioisotopes; Genotype; Hydrocarbons, Fluorinated; Hypoxia; Immunohistochemistry; Insulin-Like Growth Factor II; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitroimidazoles; Phenotype; Positron-Emission Tomography; Radiopharmaceuticals; Receptors, LDL; Tissue Distribution

2011
Mycobacterium tuberculosis infection induces hypoxic lung lesions in the rat.
    Tuberculosis (Edinburgh, Scotland), 2011, Volume: 91, Issue:4

    Topics: Animals; Disease Models, Animal; Female; Granuloma; Hypoxia; Immunohistochemistry; Lung; Mycobacterium tuberculosis; Nitroimidazoles; Rats; Tuberculosis, Pulmonary

2011
CNS hypoxia is more pronounced in murine cerebral than noncerebral malaria and is reversed by erythropoietin.
    The American journal of pathology, 2011, Volume: 179, Issue:4

    Topics: Animals; Brain; Disease Models, Animal; Erythropoietin; Female; Fluorescent Dyes; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Malaria, Cerebral; Mice; Nitroimidazoles; Parasitemia; Plasmodium berghei; Poly(ADP-ribose) Polymerases; Survival Analysis; Treatment Outcome

2011
HIF-VEGF pathways are critical for chronic otitis media in Junbo and Jeff mouse mutants.
    PLoS genetics, 2011, Volume: 7, Issue:10

    Topics: Animals; Blister; Body Fluids; Cell Hypoxia; Disease Models, Animal; Ear, Middle; Gene Expression Regulation; Hearing Loss; HSP90 Heat-Shock Proteins; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Indoles; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Mutant Strains; Nitroimidazoles; Otitis Media with Effusion; Phthalazines; Pyridines; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Signal Transduction; Sunitinib; Vascular Endothelial Growth Factor A

2011
Tumor microenvironment-dependent 18F-FDG, 18F-fluorothymidine, and 18F-misonidazole uptake: a pilot study in mouse models of human non-small cell lung cancer.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2012, Volume: 53, Issue:8

    Topics: Animals; Biological Transport; Bromodeoxyuridine; Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Dideoxynucleosides; Disease Models, Animal; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Lung Neoplasms; Mice; Misonidazole; Necrosis; Nitroimidazoles; Pilot Projects; Positron-Emission Tomography; Radioactive Tracers; Tumor Microenvironment

2012
Chronic activation of vasopressin V2 receptor signalling lowers renal medullary oxygen levels in rats.
    Acta physiologica (Oxford, England), 2013, Volume: 207, Issue:4

    Topics: Animals; Deamino Arginine Vasopressin; Disease Models, Animal; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Kidney Medulla; Nitroimidazoles; Oxygen; Rats; Rats, Brattleboro; Rats, Sprague-Dawley; Receptors, Vasopressin; Signal Transduction; Vasopressins

2013
Chronic liver injury in rats and humans upregulates the novel enzyme angiotensin converting enzyme 2.
    Gut, 2005, Volume: 54, Issue:12

    Topics: Angiotensin I; Angiotensin-Converting Enzyme 2; Animals; Aorta, Thoracic; Carboxypeptidases; Cell Hypoxia; Cells, Cultured; Chronic Disease; Disease Models, Animal; Female; Hepatitis C, Chronic; Hepatocytes; Humans; Immunoenzyme Techniques; Liver; Liver Cirrhosis; Male; Nitroimidazoles; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Up-Regulation; Vasodilation

2005
Oxygen status of lung granulomas in Mycobacterium tuberculosis-infected mice.
    The Journal of pathology, 2006, Volume: 210, Issue:3

    Topics: Animals; Biomarkers; Disease Models, Animal; Electrodes; Female; Granuloma; Hypoxia; Immunohistochemistry; Lung; Mice; Mice, Inbred C57BL; Mutation; Mycobacterium tuberculosis; Necrosis; Nitrates; Nitroimidazoles; Oxygen; Time Factors; Tuberculosis, Pulmonary

2006
Tuberculous granulomas are hypoxic in guinea pigs, rabbits, and nonhuman primates.
    Infection and immunity, 2008, Volume: 76, Issue:6

    Topics: Animals; Antitubercular Agents; Disease Models, Animal; Granuloma; Guinea Pigs; Humans; Hypoxia; Immunohistochemistry; Lung; Macaca fascicularis; Metronidazole; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mycobacterium tuberculosis; Nitroimidazoles; Oxygen; Rabbits; Radiation-Sensitizing Agents; Tuberculosis, Pulmonary

2008
Chronic enteral ethanol treatment causes hypoxia in rat liver tissue in vivo.
    Hepatology (Baltimore, Md.), 1997, Volume: 25, Issue:4

    Topics: Animals; Aspartate Aminotransferases; Cell Hypoxia; Disease Models, Animal; Ethanol; Liver; Liver Diseases, Alcoholic; Male; Nitroimidazoles; Rats; Rats, Wistar

1997
Hypoxia in a human intracerebral glioma model.
    Journal of neurosurgery, 2000, Volume: 93, Issue:3

    Topics: Animals; Brain Neoplasms; Cell Division; Disease Models, Animal; Glioma; Hypoxia; Mice; Mice, Inbred BALB C; Microcirculation; Nitroimidazoles; Radiation-Sensitizing Agents

2000
Effects of nicotinamide and carbogen on oxygenation in human tumor xenografts measured with luminescense based fiber-optic probes.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2000, Volume: 57, Issue:1

    Topics: Analysis of Variance; Animals; Carbon Dioxide; Cell Hypoxia; Disease Models, Animal; Fiber Optic Technology; Humans; Linear Models; Luminescent Measurements; Niacinamide; Nitroimidazoles; Optical Fibers; Oxygen; Radiation-Sensitizing Agents; Sensitivity and Specificity; Transplantation, Heterologous; Tumor Cells, Cultured

2000